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$161+ Cheap flights from Charleston (CHS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheap flight deals from Charleston to Panama

Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$387
(United)

One-way from

$161
(Delta)

Popular in

March

Cheapest in

July

Average price

$642
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
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From Charleston to Panama
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One-way flight from Charleston to Panama
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Highest demand for flights based on searches. 17% potential increase in price ($110 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Charleston to Panama

Cheapest flights from Charleston to Panama
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This United deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:00 amCHS - PTY
1 stop12h 37mUnited Airlines
Mon 5/1210:00 amPTY - CHS
1 stop10h 40mUnited Airlines
Deal found 3/31$387
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:30 pmCHS - PTY
2 stops18h 49mAmerican Airlines
Thu 5/221:20 pmPTY - CHS
2 stops9h 55mAmerican Airlines
Deal found 3/30$410
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/59:43 amCHS - PTY
2 stops15h 27mMultiple Airlines
Sat 6/73:20 amPTY - CHS
3 stops31h 13mMultiple Airlines
Deal found 3/31$632

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Charleston

Fly to

Panama

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/8

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 5/12

10:00 am-9:40 pm

1 stop10h 40m

$387

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 5/15

6:30 pm-12:19 pm

2 stops18h 49m

Panama City Tocumen Intl

Thu 5/22

1:20 pm-12:15 am

2 stops9h 55m

$410

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/5

9:43 am-12:10 am

2 stops15h 27m

Panama City Tocumen Intl

Sat 6/7

3:20 am-11:33 am

3 stops31h 13m

$632

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 5/19

6:37 am-12:48 pm

1 stop7h 11m

$161

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/5

7:00 am-6:37 pm

1 stop12h 37m

$174

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/5

8:30 pm-1:00 pm

2 stops17h 30m

$194

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 6/5

9:43 am-12:45 am

3 stops40h 02m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Best time to book a flight from Charleston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama

What is the cheapest month to book a flight from Charleston to Panama?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $478). Flying from Charleston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PA?

Find hourly flight availability from Charleston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated April 2, 2025.
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,615 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Entertainment

7.9

Crew

8.5

Boarding

8.2

Comfort

8.0

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Panama?

    For a flight from Charleston to Panama, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • What are the cheapest airlines to fly from Charleston to Panama one-way?

    The cheapest airlines for a one-way flight from Charleston to Panama are Delta ($161), United Airlines ($174), and American Airlines ($194).

  • Can I find deals for flights from Charleston to Panama that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama.

  • Can I find deals for business class flights from Charleston to Panama?

    Yes. Cheapflights offers flight deals from Charleston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $478). Flying from Charleston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to San José flights
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Charleston to Panama City flights
Greenville to Guatemala City flights
Myrtle Beach to San José flights
Savannah to San José flights
Augusta to San José flights
Myrtle Beach to Philip S.W.Goldson flights
Charleston to Coxen Hole flights
Augusta to Panama City flights
Greenville to San Salvador flights
Charleston to Managua flights
Savannah to Liberia flights
Greenville to Liberia flights
Myrtle Beach to Panama City flights
Savannah to Guatemala City flights
Myrtle Beach to Managua flights
Charleston to San Salvador flights
Columbia to Guatemala City flights
Greenville to San Pedro Sula flights
Savannah to Philip S.W.Goldson flights
Savannah to San Salvador flights
Myrtle Beach to Coxen Hole flights
Columbia to Philip S.W.Goldson flights
Myrtle Beach to Guatemala City flights
Charlotte to Tegucigalpa flights
Savannah to Coxen Hole flights
Savannah to San Pedro Sula flights
Augusta to Guatemala City flights
Charleston to Tegucigalpa flights
Augusta to Philip S.W.Goldson flights

Top 3 airlines flying from Charleston to Panama

Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$301Average$411FlexibilityNo cancel feeOn-time69%
DeltaCheapest$331Average$541FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$351Average$547FlexibilityNo cancel feeOn-time71%

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