HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$497+ Cheap flights from Buffalo (BUF) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/27. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
abr. 22 — abr. 291
mar. 4/22
mar. 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Buffalo to Panama

Keep the following information in mind while searching for Buffalo to Panama flight deals. Data was last updated abril 17, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$497
(Delta)

Popular in

March

Cheapest in

April

Average price

$455
Provider with most accurate pricing for Buffalo-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Panama City Tocumen Intl flights.
Search Deals
From Buffalo to Panama
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Buffalo to Panama

Cheapest flights from Buffalo to Panama
Explore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 17, 2025.

This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/277:46 pmBUF - PTY
1 stop18h 22mDelta
mar. 8/262:12 pmPTY - BUF
1 stop8h 47mDelta
Deal found 4/16$497
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/306:00 amBUF - PTY
2 stops13h 37mUnited Airlines
vie. 8/2910:55 pmPTY - BUF
2 stops20h 36mUnited Airlines
Deal found 4/16$546
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/277:53 pmBUF - PTY
2 stops19h 32mAmerican Airlines
vie. 8/293:16 pmPTY - BUF
2 stops20h 29mAmerican Airlines
Deal found 4/16$552
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/19:51 amBUF - PTY
1 stop25h 44mMultiple Airlines
jue. 5/89:34 amPTY - BUF
2 stops22h 27mMultiple Airlines
Deal found 4/17$957
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/127:55 pmBUF - PTY
3 stops17h 40mAvianca
lun. 5/1910:05 pmPTY - BUF
2 stops22h 17mAvianca
Deal found 4/16$1,019

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
Use the filters below to find and compare flights from Buffalo to Panama that are best for you.

Fly from

Buffalo

Fly to

Panama

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

vie. 6/27

7:46 pm-1:08 pm

1 stop18h 22m

Panama City Tocumen Intl

sáb. 8/30

2:12 pm-11:59 pm

1 stop8h 47m

$497

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

lun. 6/30

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

vie. 8/29

10:55 pm-8:31 pm

2 stops20h 36m

$546

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

vie. 6/27

7:53 pm-2:25 pm

2 stops19h 32m

Panama City Tocumen Intl

vie. 8/29

3:16 pm-12:45 pm

2 stops20h 29m

$552

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

jue. 5/1

9:51 am-10:35 am

1 stop25h 44m

Panama City Tocumen Intl

jue. 5/8

9:34 am-9:01 am

2 stops22h 27m

$957

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

lun. 5/12

7:55 pm-12:35 pm

3 stops17h 40m

Panama City Tocumen Intl

lun. 5/19

10:05 pm-9:22 pm

2 stops22h 17m

$1,019

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Best time to book a flight from Buffalo to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama

What is the cheapest month to book a flight from Buffalo to Panama?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PA?

Find hourly flight availability from Buffalo to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated abril 17, 2025.
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,316 reviews
Delta
8.0
Very good
7,916 reviews

Boarding

8.2

Comfort

7.9

Overall

8.0

Food

7.3

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Panama?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Panama.

  • Can I find deals for flights from Buffalo to Panama that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama.

  • Can I find deals for business class flights from Buffalo to Panama?

    Yes. Cheapflights offers flight deals from Buffalo to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San José flights
John F Kennedy Intl to Panama City flights
Newark to San José flights
Newark to Panama City flights
John F Kennedy Intl to Guatemala City flights
John F Kennedy Intl to San Salvador flights
Newark to Liberia flights
John F Kennedy Intl to Liberia flights
LaGuardia to San José flights
Newark to Guatemala City flights
LaGuardia to Panama City flights
Newark to San Salvador flights
LaGuardia to Liberia flights
Newark to Philip S.W.Goldson flights
LaGuardia to Guatemala City flights
LaGuardia to Philip S.W.Goldson flights
John F Kennedy Intl to Philip S.W.Goldson flights
John F Kennedy Intl to San Pedro Sula flights
LaGuardia to San Salvador flights
Newark to San Pedro Sula flights
John F Kennedy Intl to Managua flights
LaGuardia to San Pedro Sula flights
Newark to Managua flights
LaGuardia to Managua flights
Newark to Coxen Hole flights
John F Kennedy Intl to Coxen Hole flights
LaGuardia to Coxen Hole flights
Rochester to San José flights
Stewart to San José flights
Buffalo to San José flights
Albany to San José flights
Syracuse to San José flights
Syracuse to Liberia flights
White Plains to Philip S.W.Goldson flights
Syracuse to Panama City flights
Albany to Panama City flights
Buffalo to Philip S.W.Goldson flights
Rochester to Panama City flights
Stewart to Guatemala City flights
White Plains to San Salvador flights
Rochester to Liberia flights
White Plains to Panama City flights
Buffalo to Panama City flights
John F Kennedy Intl to David flights
Albany to Liberia flights
Ithaca to San José flights
Syracuse to Philip S.W.Goldson flights
Rochester to Philip S.W.Goldson flights
Syracuse to Guatemala City flights
White Plains to Liberia flights

Top 2 airlines flying from Buffalo to Panama

Discover the top 2 airlines that operate flights from Buffalo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$421Average$587FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$455Average$594FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.