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$186+ Cheap flights from Buffalo (BUF) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/31. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Buffalo to Panama

Keep the following information in mind while searching for Buffalo to Panama flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$467
(Delta)

One-way from

$186
(Delta)

Popular in

March

Cheapest in

October

Average price

$510
Provider with most accurate pricing for Buffalo-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Panama City Tocumen Intl flights.
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From Buffalo to Panama
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One-way flight from Buffalo to Panama
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Buffalo to Panama

Cheapest flights from Buffalo to Panama
Explore the most affordable flight options available from Buffalo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:00 amBUF - PTY
1 stop7h 55mDelta
Wed 4/22:20 pmPTY - BUF
1 stop8h 47mDelta
Deal found 2/20$467
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1910:30 amBUF - PTY
2 stops28h 15mUnited Airlines
Wed 4/210:55 pmPTY - BUF
2 stops17h 00mUnited Airlines
Deal found 2/20$472
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1911:24 amBUF - PTY
1 stop9h 04mMultiple Airlines
Tue 4/13:20 amPTY - BUF
2 stops30h 04mMultiple Airlines
Deal found 2/20$714
This Avianca deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/197:00 amBUF - PTY
2 stops18h 20mAvianca
Tue 4/13:20 amPTY - BUF
2 stops16h 51mAvianca
Deal found 2/20$1,112

Find flights from Buffalo to Panama within your budget

Customize your flight search to find flights from Buffalo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Buffalo

Fly to

Panama

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/19

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 4/2

2:20 pm-12:07 am

1 stop8h 47m

$467

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/19

10:30 am-1:45 pm

2 stops28h 15m

Panama City Tocumen Intl

Wed 4/2

10:55 pm-4:55 pm

2 stops17h 00m

$472

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/19

11:24 am-7:28 pm

1 stop9h 04m

Panama City Tocumen Intl

Tue 4/1

3:20 am-10:24 am

2 stops30h 04m

$714

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 3/19

7:00 am-12:20 am

2 stops18h 20m

Panama City Tocumen Intl

Tue 4/1

3:20 am-9:11 pm

2 stops16h 51m

$1,112

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/31

6:00 am-12:55 pm

1 stop7h 55m

$186

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/31

7:45 pm-6:37 pm

2 stops23h 52m

$192

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/31

11:24 am-10:32 am

3 stops24h 08m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Best time to book a flight from Buffalo to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Buffalo to Panama

Get recent, data-driven insights about flights from Buffalo to Panama including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Buffalo to Panama?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PA?

Find hourly flight availability from Buffalo to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to Panama as you normally would.

Rainfall in Panama by month

Plan your trip to Panama by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

Temperature in Panama by month

Plan your trip to Panama by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 22, 2025.
Delta
8.0
Very good
8,203 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Delta
8.0
Very good
8,203 reviews
Delta
8.0
Very good
8,203 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

United Airlines
7.4
Good
8,754 reviews
Delta
8.0
Very good
8,203 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Avianca
6.8
Okay
2,425 reviews
Delta
8.0
Very good
8,203 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.9

Overall

8.0

Food

7.3

Crew

8.5

Reviews

1 / 20

10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Panama?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Panama.

  • Can I find deals for flights from Buffalo to Panama that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama.

  • Can I find deals for business class flights from Buffalo to Panama?

    Yes. Cheapflights offers flight deals from Buffalo to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama (average of $478). Flying from Buffalo to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Buffalo to Panama

Discover the top 2 airlines that operate flights from Buffalo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$421Average$596FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$455Average$623FlexibilityNo cancel feeOn-time69%
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