HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$212+ Cheap flights from Spartanburg, SC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/11. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
abr. 8 — abr. 151
mar. 4/8
mar. 4/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Spartanburg to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Spartanburg to Panama City Tocumen Intl are usually found in September or May, booked 51 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Spartanburg to Panama City

Keep the following information in mind while searching for Spartanburg to Panama City flight deals. Data was last updated abril 3, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$390
(Avianca Connect)

One-way from

$212
(Delta)

Popular in

December

Cheapest in

September

Average price

$523
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
Search Deals
From Spartanburg to Panama City Tocumen Intl
Search Deals
One-way flight from Spartanburg to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($115 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($30 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Spartanburg to Panama City

Cheapest flights from Spartanburg to Panama City
Explore the most affordable flight options available from Spartanburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 3, 2025.

This Avianca Connect deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/210:19 pmCLT - PTY
2 stops21h 56mMultiple Airlines
jue. 5/83:20 amPTY - CLT
2 stops15h 09mMultiple Airlines
Deal found 4/2$390
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/106:13 amCLT - PTY
1 stop13h 24mUnited Airlines
lun. 4/1410:00 amPTY - CLT
1 stop10h 59mUnited Airlines
Deal found 4/2$417
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/16:01 amCLT - PTY
1 stop7h 14mAmerican Airlines
jue. 5/81:20 pmPTY - CLT
2 stops16h 08mAmerican Airlines
Deal found 4/2$422
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/135:30 amCLT - PTY
1 stop8h 24mDelta
jue. 8/282:12 pmPTY - CLT
1 stop7h 13mDelta
Deal found 3/31$447
This Avianca deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/16:00 amCLT - PTY
2 stops19h 10mAvianca
jue. 5/85:25 pmPTY - CLT
2 stops15h 20mAvianca
Deal found 4/2$840

Cheapflights Fare Finder

Customize your flight search to find flights from Spartanburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 3, 2025.
Use the filters below to find and compare flights from Spartanburg to Panama City that are best for you.

Fly from

Spartanburg

Fly to

Panama City

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

vie. 5/2

10:19 pm-7:15 pm

2 stops21h 56m

Panama City Tocumen Intl

jue. 5/8

3:20 am-7:29 pm

2 stops15h 09m

$390

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 4/10

6:13 am-6:37 pm

1 stop13h 24m

Panama City Tocumen Intl

lun. 4/14

10:00 am-9:59 pm

1 stop10h 59m

$417

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 5/1

6:01 am-12:15 pm

1 stop7h 14m

Panama City Tocumen Intl

jue. 5/8

1:20 pm-6:28 am

2 stops16h 08m

$422

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

vie. 4/25

7:10 am-12:55 pm

1 stop6h 45m

Panama City Tocumen Intl

sáb. 5/3

7:30 am-7:52 pm

1 stop11h 22m

$453

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

jue. 5/1

6:00 am-12:10 am

2 stops19h 10m

Panama City Tocumen Intl

jue. 5/8

5:25 pm-9:45 am

2 stops15h 20m

$840

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

vie. 4/11

9:44 am-7:27 pm

1 stop10h 43m

$212

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

dom. 6/29

6:35 am-1:50 pm

1 stop8h 15m

$231

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

vie. 4/11

10:19 pm-7:15 pm

2 stops21h 56m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Best time to book a flight from Spartanburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Panama City

How far ahead should I book a flight from Spartanburg to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Panama City. Price data was last updated on March 28, 2025.

The best time to book flights from Spartanburg to Panama City is 51 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Spartanburg to Panama City?

Currently, October is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $478). Flying from Spartanburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to PTY?

Find hourly flight availability from Spartanburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Spartanburg to Panama City as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated abril 3, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Spartanburg to Panama City. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

8.0

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

8.0

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,619 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

8.0

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

8.0

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.7
Okay
2,304 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Boarding

8.2

Crew

8.5

Comfort

8.0

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spartanburg?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Spartanburg to Panama City. You should not have trouble finding flights to Tocumen Intl from Spartanburg; the airport handles an average of 0 inbound flights from Spartanburg per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Spartanburg. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • Can I find deals for flights from Spartanburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Panama City.

  • Can I find deals for business class flights from Spartanburg to Panama City?

    Yes. Cheapflights offers flight deals from Spartanburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $478). Flying from Spartanburg to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Spartanburg to Panama City

Discover the top 3 airlines that operate flights from Spartanburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$458FlexibilityNo cancel feeOn-time69%
DeltaCheapest$281Average$610FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$352Average$577FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.