$156+ Cheap flights from South Carolina to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from South Carolina to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Panama City
Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated March 31, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $364 (American Airlines) |
One-way from | $156 (Avianca Connect) |
Popular in | March |
Cheapest in | June |
Average price | $788 |
Find flight deals from South Carolina to Panama City
Cheapest flights from South Carolina to Panama CityExplore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Avianca Connect deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Mon 5/5
8:35 pm-12:19 pm
2 stops16h 44m
Panama City Tocumen Intl
Thu 5/8
1:20 pm-11:15 am
2 stops20h 55m
GreenvillePanama City
GSP - PTY
GSPPTY
Greenville
Mon 5/5
4:12 pm-6:37 pm
1 stop27h 25m
Panama City Tocumen Intl
Thu 5/8
3:20 pm-10:15 pm
1 stop29h 55m
CharlottePanama City
CLT - PTY
CLTPTY
Charlotte Douglas
Thu 5/15
6:00 am-9:10 pm
2 stops16h 10m
Panama City Tocumen Intl
Sun 5/18
5:25 pm-11:03 am
2 stops16h 38m
CharlestonPanama City
CHS - PTY
CHSPTY
Charleston
Thu 5/8
7:00 am-6:37 pm
1 stop12h 37m
Panama City Tocumen Intl
Mon 5/12
10:00 am-9:40 pm
1 stop10h 40m
SavannahPanama City
SAV - PTY
SAVPTY
Savannah/Hilton Head
Tue 4/29
6:52 am-12:15 pm
1 stop6h 23m
Panama City Tocumen Intl
Thu 5/8
1:20 pm-11:22 pm
1 stop9h 02m
CharlestonPanama City
CHS - PTY
CHSPTY
Charleston
Thu 5/8
4:10 pm-12:19 pm
2 stops21h 09m
Panama City Tocumen Intl
Mon 5/12
1:20 pm-10:45 am
2 stops20h 25m
CharlottePanama City
CLT - PTY
CLTPTY
Charlotte Douglas
Thu 4/10
6:13 am-4:12 pm
1 stop10h 59m
Panama City Tocumen Intl
Mon 4/14
7:55 am-9:59 pm
1 stop13h 04m
ColumbiaPanama City
CAE - PTY
CAEPTY
Columbia Metropolitan
Tue 8/12
5:30 am-2:15 pm
2 stops9h 45m
Panama City Tocumen Intl
Tue 8/26
3:16 pm-10:10 am
2 stops17h 54m
CharlottePanama City
CLT - PTY
CLTPTY
Charlotte Douglas
Mon 5/12
6:00 am-12:19 pm
1 stop7h 19m
Panama City Tocumen Intl
Mon 5/19
1:20 pm-6:28 am
2 stops16h 08m
AugustaPanama City
AGS - PTY
AGSPTY
Augusta Bush Field
Thu 4/10
12:42 pm-12:15 pm
2 stops24h 33m
Panama City Tocumen Intl
Sun 4/13
1:05 pm-7:14 am
2 stops17h 09m
Best time to book a flight from South Carolina to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Panama City
What is the cheapest month to book a flight from South Carolina to Panama City?
Currently, October is the cheapest month in which you can book a flight from South Carolina to Panama City (average of $478). Flying from South Carolina to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to PTY?
Find hourly flight availability from South Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.
When flying from South Carolina to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in Panama City by month
Plan your trip to Panama City by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.
Temperature in Panama City by month
Plan your trip to Panama City by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 31, 2025.
See what other customers who have flown with Delta, Copa Airlines and United Airlines from South Carolina to Panama City have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Crew
Comfort
Entertainment
Boarding
Food
Overall
Reviews
Aaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for South Carolina to Panama City
See prices for flight routes from nearby airports that may be better suited for you.
Top 3 airlines flying from South Carolina to Panama City
Discover the top 3 airlines that operate flights from South Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$281 | Average$396 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$331 | Average$626 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$351 | Average$562 | FlexibilityNo cancel fee | On-time71% |