How popular is this Massachusetts to Panama City flight route?

Within the past month, 203 users have taken a look at flights from Massachusetts to Panama City Tocumen Intl.

What are the cheapest airlines to fly from Massachusetts to Panama City one-way?

The cheapest airlines for a one-way flight from Massachusetts to Panama City are Avianca ($199), American Airlines ($243), and Delta ($263).

What are the most popular routes from Massachusetts to Panama City?

While some choose either Hartford Bradley Intl - Panama City Tocumen Intl or Albany Intl - Panama City Tocumen Intl, Boston Logan Intl - Panama City Tocumen Intl is the most popular route from Massachusetts to Panama City.

What are the cheapest flights from Massachusetts to Panama City?

Looking at all options, your cheapest flight can be booked for $167. While the most popular route (Boston Logan Intl - Panama City Tocumen Intl) can be booked for $422 on average our data indicates $1,276 when flying from Massachusetts to Panama City.

What are the most popular airlines that fly from Massachusetts to Panama City?

American Airlines, Avianca and Copa Airlines are the most popular airlines when flying from Massachusetts to Panama City.

How far in advance should I book a flight from Massachusetts to Panama City?

Users have found that booking a flight from Massachusetts to Panama City at least 18 days early can save you up to 38% on average compared to booking a flight this week. If booking 18 days before your flight isn’t an option for you, users have found flights from Massachusetts to Panama City for as little as $480 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $628 for flights departing within the next 3 days.

What is the cheapest month to fly from Massachusetts to Panama City?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, October can be a great choice for travel to Panama City. Flights to Panama City from Massachusetts in October are about $589 on average during October, but can be found for as low as $454.

What airport do you fly into for flights to Panama City from Massachusetts?

Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Massachusetts to Panama City.

Can I find deals for flights from Massachusetts to Panama City that include hotel bookings?

Yes. In addition to deals on Massachusetts to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Massachusetts to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Panama City.

Can I find deals for business class flights from Massachusetts to Panama City?

Yes. Cheapflights offers flight deals from Massachusetts to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$199+ Flights from Massachusetts to Panama City

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Cheap flight deals from Massachusetts to Panama City

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$461 (Delta)
One-way from	$199 (Cheapflightsfares)
Popular in	December
Cheapest in	October
Average price	$632
Good round-trip deal	$502 or less
Good one-way deal	$218 or less

Provider with most accurate pricing for Boston Logan Intl-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Boston Logan Intl-Panama City Tocumen Intl flights.

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From Massachusetts to Panama City Tocumen Intl

Search Deals

One-way flight from Massachusetts to Panama City Tocumen Intl

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($55 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($27 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Massachusetts to Panama City Tocumen Intl.

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Price to beat on a one-way flight from Massachusetts to Panama City Tocumen Intl.

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Find flight deals from Massachusetts to Panama City

Cheapest flights from Massachusetts to Panama City
Explore the most affordable flight options available from Massachusetts to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Mon 5/56:05 amALB - PTY

1 stop7h 50mDelta

Thu 5/82:13 pmPTY - ALB

1 stop8h 48mDelta

Deal found 4/1

$461

Sun 4/137:30 pmALB - PTY

2 stops21h 42mUnited Airlines

Wed 4/163:20 pmPTY - ALB

2 stops22h 06mUnited Airlines

Deal found 3/31

$466

Thu 4/176:15 amBDL - PTY

2 stops13h 22mUnited Airlines

Tue 4/223:20 pmPTY - BDL

2 stops21h 45mUnited Airlines

Deal found 4/1

$480

Fri 5/166:10 amBOS - PTY

2 stops16h 00mMultiple Airlines

Thu 5/223:20 amPTY - BOS

2 stops19h 09mMultiple Airlines

Deal found 4/1

$483

Mon 5/195:12 pmALB - PTY

2 stops20h 07mAmerican Airlines

Wed 6/41:20 pmPTY - ALB

2 stops10h 38mAmerican Airlines

Deal found 4/1

$484

Wed 6/44:50 pmBOS - PTY

1 stop18h 35mAvianca

Sat 6/148:10 pmPTY - BOS

1 stop17h 45mAvianca

Deal found 3/31

$491

Mon 4/76:39 pmBOS - PTY

2 stops18h 36mAmerican Airlines

Tue 4/151:15 pmPTY - BOS

2 stops18h 28mAmerican Airlines

Deal found 3/31

$492

Tue 5/205:44 amBDL - PTY

1 stop7h 35mAmerican Airlines

Sat 5/241:20 pmPTY - BDL

1 stop8h 53mAmerican Airlines

Deal found 4/1

$493

Thu 5/223:55 pmBOS - PTY

Nonstop5h 46mCopa Airlines

Sat 5/3112:39 pmPTY - BOS

Nonstop5h 47mCopa Airlines

Deal found 4/1

$516

Sat 9/66:00 amBDL - PTY

1 stop7h 54mDelta

Sat 9/132:14 pmPTY - BDL

1 stop8h 32mDelta

Deal found 4/1

$551

Thu 9/117:40 amBOS - PTY

1 stop11h 57mUnited Airlines

Tue 9/169:45 amPTY - BOS

1 stop10h 10mUnited Airlines

Deal found 3/31

$573

Thu 4/1712:55 pmBDL - PTY

2 stops33h 15mMultiple Airlines

Mon 4/213:25 amPTY - BDL

3 stops29h 02mMultiple Airlines

Deal found 4/1

$608

Best flights from Massachusetts to Panama City
Discover carefully curated flight deals from Massachusetts to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2025.

Mon 5/56:05 amALB - PTY

1 stop7h 50mDelta

Thu 5/82:13 pmPTY - ALB

1 stop8h 48mDelta

Deal found 4/1

$461

Sun 4/137:30 pmALB - PTY

2 stops21h 42mUnited Airlines

Wed 4/163:20 pmPTY - ALB

2 stops22h 06mUnited Airlines

Deal found 3/31

$466

Fri 5/166:10 amBOS - PTY

2 stops16h 00mMultiple Airlines

Thu 5/223:20 amPTY - BOS

2 stops19h 09mMultiple Airlines

Deal found 4/1

$483

Mon 5/195:12 pmALB - PTY

2 stops20h 07mAmerican Airlines

Wed 6/41:20 pmPTY - ALB

2 stops10h 38mAmerican Airlines

Deal found 4/1

$484

Wed 6/44:50 pmBOS - PTY

1 stop18h 35mAvianca

Sat 6/148:10 pmPTY - BOS

1 stop17h 45mAvianca

Deal found 3/31

$491

Thu 5/223:55 pmBOS - PTY

Nonstop5h 46mCopa Airlines

Sat 5/3112:39 pmPTY - BOS

Nonstop5h 47mCopa Airlines

Deal found 4/1

$516

Wed 4/164:49 pmBDL - PTY

2 stops26h 48mUnited Airlines

Mon 4/213:20 pmPTY - BDL

2 stops18h 20mUnited Airlines

Deal found 3/31

$480

Tue 5/205:44 amBDL - PTY

1 stop7h 35mAmerican Airlines

Sat 5/241:20 pmPTY - BDL

1 stop8h 53mAmerican Airlines

Deal found 4/1

$493

Sat 9/66:00 amBDL - PTY

1 stop7h 54mDelta

Sat 9/132:14 pmPTY - BDL

1 stop8h 32mDelta

Deal found 3/31

$551

Thu 4/1712:55 pmBDL - PTY

2 stops33h 15mMultiple Airlines

Mon 4/213:25 amPTY - BDL

3 stops29h 02mMultiple Airlines

Deal found 4/1

$608

Thu 9/117:40 amBOS - PTY

1 stop11h 57mUnited Airlines

Tue 9/169:45 amPTY - BOS

1 stop10h 10mUnited Airlines

Deal found 3/31

$573

Thu 6/268:11 pmBOS - PTY

2 stops19h 14mAmerican Airlines

Sun 6/291:50 pmPTY - BOS

1 stop23h 38mAmerican Airlines

Deal found 3/30

$592

Last-minute flights from Massachusetts to Panama City
Discover last-minute flight deals from Massachusetts to Panama City. Data last updated April 2, 2025 and is based on user searches.

Sun 4/66:00 amBOS - PTY

2 stops13h 37mUnited Airlines

Sat 4/129:45 amPTY - BOS

2 stops13h 14mUnited Airlines

Deal found 3/30

$968

Mon 4/76:39 pmBOS - PTY

2 stops18h 36mAmerican Airlines

Tue 4/151:15 pmPTY - BOS

2 stops18h 28mAmerican Airlines

Deal found 3/31

$492

Mon 4/78:28 amBOS - PTY

Nonstop6h 05mCopa Airlines

Sat 4/1212:39 pmPTY - BOS

Nonstop5h 41mCopa Airlines

Deal found 3/31

$949

Tue 4/89:00 amBOS - PTY

1 stop16h 10mMultiple Airlines

Tue 4/1510:05 pmPTY - BOS

2 stops24h 41mMultiple Airlines

Deal found 3/31

$486

Tue 4/87:40 pmBDL - PTY

2 stops21h 32mUnited Airlines

Fri 4/187:55 amPTY - BDL

2 stops25h 45mUnited Airlines

Deal found 4/1

$498

Tue 4/86:00 amBDL - PTY

1 stop7h 58mDelta

Fri 4/182:20 pmPTY - BDL

1 stop8h 39mDelta

Deal found 4/1

$645

Tue 4/85:40 amBDL - PTY

1 stop7h 35mAmerican Airlines

Fri 4/181:15 pmPTY - BDL

2 stops17h 42mAmerican Airlines

Deal found 4/1

$765

Wed 4/94:50 pmBOS - PTY

1 stop18h 35mAvianca

Mon 4/215:25 pmPTY - BOS

1 stop12h 50mAvianca

Deal found 3/31

$625

Sun 4/137:30 pmALB - PTY

2 stops21h 42mUnited Airlines

Wed 4/163:20 pmPTY - ALB

2 stops22h 06mUnited Airlines

Deal found 3/31

$466

Thu 4/176:15 amBDL - PTY

2 stops13h 22mUnited Airlines

Tue 4/223:20 pmPTY - BDL

2 stops21h 45mUnited Airlines

Deal found 4/1

$480

Thu 4/1712:55 pmBDL - PTY

2 stops33h 15mMultiple Airlines

Mon 4/213:25 amPTY - BDL

3 stops29h 02mMultiple Airlines

Deal found 4/1

$608

Wed 4/304:50 pmBOS - PTY

1 stop18h 35mAvianca

Wed 5/145:25 pmPTY - BOS

1 stop12h 50mAvianca

Deal found 3/31

$506

One-way flights from Massachusetts to Panama City
Search for one-way flight options from Massachusetts to Panama City. Find affordable one-way fares based on user searches. Data last updated April 2, 2025.

Sat 5/109:00 amBOS - PTY

1 stop16h 10mAvianca

Deal found 4/1

$199

Sat 5/104:49 pmBOS - PTY

2 stops29h 21mMultiple Airlines

Deal found 4/1

$208

Sun 6/225:34 pmBDL - PTY

2 stops21h 51mAmerican Airlines

Deal found 4/2

$243

Sat 6/712:36 pmBDL - PTY

1 stop8h 17mDelta

Deal found 4/2

$263

Fri 5/2312:27 pmBDL - PTY

2 stops36h 43mMultiple Airlines

Deal found 4/1

$307

Tue 7/226:26 pmBOS - PTY

2 stops19h 28mAmerican Airlines

Deal found 4/1

$459

Tue 7/226:59 pmBOS - PTY

3 stops20h 15mUnited Airlines

Deal found 4/1

$465

Sat 5/108:47 amBOS - PTY

Nonstop5h 46mCopa Airlines

Deal found 4/1

$671

Sat 6/76:00 amBDL - PTY

3 stops31h 35mAvianca

Deal found 4/2

$730

Cheapflights Fare Finder

Use the filters below to find and compare flights from Massachusetts to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Mon 5/5

6:05 am-12:55 pm

1 stop7h 50m

Panama City Tocumen Intl

Thu 5/8

2:13 pm-12:01 am

1 stop8h 48m

$461

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Sun 4/13

7:30 pm-4:12 pm

2 stops21h 42m

Panama City Tocumen Intl

Wed 4/16

3:20 pm-2:26 pm

2 stops22h 06m

$466

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Wed 4/16

4:49 pm-6:37 pm

2 stops26h 48m

Panama City Tocumen Intl

Mon 4/21

3:20 pm-10:40 am

2 stops18h 20m

$480

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Fri 5/16

6:10 am-9:10 pm

2 stops16h 00m

Panama City Tocumen Intl

Thu 5/22

3:20 am-11:29 pm

2 stops19h 09m

$483

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Mon 5/19

5:12 pm-12:19 pm

2 stops20h 07m

Panama City Tocumen Intl

Wed 6/4

1:20 pm-12:58 am

2 stops10h 38m

$484

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Wed 6/4

4:50 pm-10:25 am

1 stop18h 35m

Panama City Tocumen Intl

Sat 6/14

8:10 pm-2:55 pm

1 stop17h 45m

$491

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Tue 5/20

5:44 am-12:19 pm

1 stop7h 35m

Panama City Tocumen Intl

Sat 5/24

1:20 pm-11:13 pm

1 stop8h 53m

$493

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 5/22

3:55 pm-8:41 pm

Nonstop5h 46m

Panama City Tocumen Intl

Sat 5/31

12:39 pm-7:26 pm

Nonstop5h 47m

$516

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Sat 9/6

6:00 am-12:54 pm

1 stop7h 54m

Panama City Tocumen Intl

Sat 9/13

2:14 pm-11:46 pm

1 stop8h 32m

$551

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 9/11

7:40 am-6:37 pm

1 stop11h 57m

Panama City Tocumen Intl

Tue 9/16

9:45 am-8:55 pm

1 stop10h 10m

$573

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 23 results

Best time to book a flight from Massachusetts to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Massachusetts with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Panama City

What is the cheapest month to book a flight from Massachusetts to Panama City?

Currently, October is the cheapest month in which you can book a flight from Massachusetts to Panama City (average of $478). Flying from Massachusetts to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to PTY?

When flying from Massachusetts to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Massachusetts to Panama City. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,898 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,400 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,615 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Avianca

6.7

Okay

2,302 reviews

Delta

8.0

Very good

7,898 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Panama City from Massachusetts?
Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Massachusetts to Panama City.
How popular is this Massachusetts to Panama City flight route?
Within the past month, 203 users have taken a look at flights from Massachusetts to Panama City Tocumen Intl.
What are the cheapest airlines to fly from Massachusetts to Panama City one-way?
The cheapest airlines for a one-way flight from Massachusetts to Panama City are Avianca ($199), American Airlines ($243), and Delta ($263).
What are the most popular routes from Massachusetts to Panama City?
While some choose either Hartford Bradley Intl - Panama City Tocumen Intl or Albany Intl - Panama City Tocumen Intl, Boston Logan Intl - Panama City Tocumen Intl is the most popular route from Massachusetts to Panama City.
What are the cheapest flights from Massachusetts to Panama City?
Looking at all options, your cheapest flight can be booked for $167. While the most popular route (Boston Logan Intl - Panama City Tocumen Intl) can be booked for $422 on average our data indicates $1,276 when flying from Massachusetts to Panama City.
Can I find deals for flights from Massachusetts to Panama City that include hotel bookings?
Yes. In addition to deals on Massachusetts to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Massachusetts to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Panama City.
Can I find deals for business class flights from Massachusetts to Panama City?
Yes. Cheapflights offers flight deals from Massachusetts to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Massachusetts to Panama City?
Currently, October is the cheapest month in which you can book a flight from Massachusetts to Panama City (average of $478). Flying from Massachusetts to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Massachusetts to Panama City

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$387	Average$645	FlexibilityNo cancel fee	On-time71%
Avianca	Cheapest$408	Average$497	FlexibilityNo cancel fee	On-time71%
Copa Airlines	Cheapest$450	Average$578	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$469	Average$589	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$492	Average$616	FlexibilityNo cancel fee	On-time69%

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$199+ Cheap flights from Massachusetts to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Massachusetts to Panama City with Cheapflights

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Cheap flight deals from Massachusetts to Panama City

Keep the following information in mind while searching for Massachusetts to Panama City flight deals. Data was last updated April 2, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Massachusetts to Panama City

Cheapest flights from Massachusetts to Panama CityExplore the most affordable flight options available from Massachusetts to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Explore the most affordable flight options available from Massachusetts to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Massachusetts to Panama City that are best for you.

Best time to book a flight from Massachusetts to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Massachusetts with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Panama City

What is the cheapest month to book a flight from Massachusetts to Panama City?

What is the cheapest time of day to fly from MA to PTY?

Find hourly flight availability from Massachusetts to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Massachusetts to Panama City. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Panama City from Massachusetts?

How popular is this Massachusetts to Panama City flight route?

What are the cheapest airlines to fly from Massachusetts to Panama City one-way?

What are the most popular routes from Massachusetts to Panama City?

What are the cheapest flights from Massachusetts to Panama City?

Can I find deals for flights from Massachusetts to Panama City that include hotel bookings?

How can I find direct flights from Massachusetts to Panama City?

Can I find deals for business class flights from Massachusetts to Panama City?

What is the cheapest month to book a flight from Massachusetts to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Massachusetts to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Massachusetts to Panama City

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Cheapest flights from Massachusetts to Panama City
Explore the most affordable flight options available from Massachusetts to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.