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$462+ Cheap flights from Knoxville (TYS) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PTY
ene. 22 — ene. 291
mié. 1/22
mié. 1/29
1 adult, Economy
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Cheap flight deals from Knoxville to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$462
(American Airlines)

Popular in

December

Cheapest in

March

Average price

$511
Provider with most accurate pricing for Knoxville McGhee Tyson-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Panama City Tocumen Intl flights.
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From Knoxville McGhee Tyson to Panama City Tocumen Intl
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High demand for flights, 24% potential price rise
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Best time to find cheap flights, 6% potential price drop
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Average for round-trip flights in January 2025
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Find flight deals from Knoxville to Panama City

Cheapest flights from Knoxville to Panama City
Explore the most affordable flight options available from Knoxville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 17, 2025.

This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/58:28 pmTYS - PTY
2 stops17h 02mAmerican Airlines
vie. 5/91:50 pmPTY - TYS
2 stops19h 16mAmerican Airlines
Deal found 1/16$462
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/57:00 amTYS - PTY
1 stop12h 37mUnited Airlines
vie. 5/93:20 pmPTY - TYS
1 stop25h 21mUnited Airlines
Deal found 1/16$536
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/279:16 pmTYS - PTY
2 stops23h 44mMultiple Airlines
sáb. 3/812:03 pmPTY - TYS
1 stop10h 49mMultiple Airlines
Deal found 1/15$561
This Avianca deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/306:20 amTYS - PTY
2 stops18h 40mAvianca
vie. 1/313:19 amPTY - TYS
2 stops16h 17mAvianca
Deal found 1/16$837

Find flights from Knoxville to Panama City within your budget

Customize your flight search to find flights from Knoxville to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 17, 2025.

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Fly to

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Route

Depart

Return

Price

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

lun. 5/5

8:28 pm-12:30 pm

2 stops17h 02m

Panama City Tocumen Intl

vie. 5/9

1:50 pm-10:06 am

2 stops19h 16m

$462

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

lun. 5/5

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

vie. 5/9

3:20 pm-5:41 pm

1 stop25h 21m

$536

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

jue. 2/27

9:16 pm-9:00 pm

2 stops23h 44m

Panama City Tocumen Intl

sáb. 3/8

12:03 pm-10:52 pm

1 stop10h 49m

$561

KnoxvillePanama City

TYS - PTY

TYSPTY

Knoxville McGhee Tyson

jue. 1/30

6:20 am-1:00 am

2 stops18h 40m

Panama City Tocumen Intl

vie. 1/31

3:19 am-7:36 pm

2 stops16h 17m

$837

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Compare providers for flights from Knoxville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Panama City

Get recent, data-driven insights about flights from Knoxville to Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Panama City?

Currently, October is the cheapest month in which you can book a flight from Knoxville to Panama City (average of $478). Flying from Knoxville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to PTY?

Find hourly flight availability from Knoxville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated enero 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Panama City as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated enero 17, 2025.
United Airlines
7.4
Good
8,964 reviews

Entertainment

7.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.7

Reviews

1 / 10

United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!

United Airlines
7.4
Good
8,964 reviews
United Airlines
7.4
Good
8,964 reviews

Entertainment

7.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.7

Reviews

1 / 10

United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!

American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,964 reviews

Entertainment

7.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.7

Reviews

1 / 10

United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!

Avianca
6.9
Okay
2,572 reviews
United Airlines
7.4
Good
8,964 reviews

Entertainment

7.1

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Food

6.7

Reviews

1 / 10

United Airlines flights seem to always use a bus to/from the boarding gate to the plane. Can they not get their own gate? This time there was no lift when leaving the plane and people in wheelchairs somehow had to climb down the steps to the ground to get to the bus. I udon’t know how some managed that!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Knoxville to Panama City round-trip?

    Flying on American Airlines is currently your cheapest option to Panama City, with prices starting at $462. Additional round-trip tickets that might be worth considering are offered by United Airlines and Avianca, with the lowest prices starting at $536 and $837, respectively. American Airlines is currently priced 20% below the average price you’ll pay for this route.

  • Can I find deals for flights from Knoxville to Panama City that include hotel bookings?

    Yes. In addition to deals on Knoxville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama City.

  • Can I find deals for business class flights from Knoxville to Panama City?

    Yes. Cheapflights offers flight deals from Knoxville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Knoxville to Panama City (average of $478). Flying from Knoxville to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Panama City

Discover the top 3 airlines that operate flights from Knoxville to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$281Average$754FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$368Average$625FlexibilityNo cancel feeOn-time71%
DeltaCheapest$427Average$548FlexibilityNo cancel feeOn-timeN/A
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