Panama City

$173+ Cheap flights from Iowa to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PTY
Feb 28 — Mar 71
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Cheap flight deals from Iowa to Panama City

Keep the following information in mind while searching for Iowa to Panama City flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$416
(United)

One-way from

$173
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$550
Provider with most accurate pricing for Des Moines-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Des Moines-Panama City Tocumen Intl flights.
From Iowa to Panama City Tocumen Intl
One-way flight from Iowa to Panama City Tocumen Intl
Highest demand for flights based on searches. 17% potential increase in price ($105 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($26 potential savings vs. average RT price).
Average for round-trip flights in February 2025

Find flight deals from Iowa to Panama City

Cheapest flights from Iowa to Panama City
Explore the most affordable flight options available from Iowa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/235:55 pmDSM - PTY
2 stops19h 07mDelta
Tue 3/43:27 pmPTY - DSM
2 stops26h 45mDelta
Deal found 2/22$404
This United deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/248:00 amDSM - PTY
1 stop10h 38mUnited Airlines
Tue 3/48:55 amPTY - DSM
1 stop14h 35mUnited Airlines
Deal found 2/23$411
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:17 pmOMA - PTY
2 stops21h 08mAmerican Airlines
Tue 11/44:20 pmPTY - OMA
1 stop8h 30mAmerican Airlines
Deal found 2/21$506
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/257:26 pmCID - PTY
2 stops19h 06mAmerican Airlines
Mon 3/313:30 pmPTY - CID
2 stops26h 23mAmerican Airlines
Deal found 2/22$506
This United deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:00 amOMA - PTY
1 stop7h 45mUnited Airlines
Tue 11/44:40 pmPTY - OMA
1 stop30h 30mUnited Airlines
Deal found 2/21$511
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:35 amOMA - PTY
1 stop7h 12mDelta
Wed 10/292:12 pmPTY - OMA
1 stop9h 41mDelta
Deal found 2/21$521
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/85:26 pmCID - PTY
2 stops20h 48mUnited Airlines
Tue 4/153:20 pmPTY - CID
2 stops19h 16mUnited Airlines
Deal found 2/22$526
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:13 pmDSM - PTY
2 stops18h 02mAmerican Airlines
Sat 5/311:20 pmPTY - DSM
2 stops21h 53mAmerican Airlines
Deal found 2/22$556
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/255:30 amCID - PTY
1 stop7h 25mDelta
Mon 3/312:20 pmPTY - CID
1 stop8h 03mDelta
Deal found 2/22$842
This Mytrip deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/77:30 amDSM - PTY
2 stops13h 40mMultiple Airlines
Sun 4/133:20 amPTY - DSM
3 stops19h 53mMultiple Airlines
Deal found 2/22$865
This flugladen.de deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/88:00 amDSM - PTY
2 stops16h 10mAvianca
Mon 4/143:25 amPTY - DSM
2 stops18h 27mAvianca
Deal found 2/22$1,128
This Travelocity deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/253:31 pmOMA - PTY
3 stops42h 54mMultiple Airlines
Wed 10/293:40 pmPTY - OMA
2 stops23h 21mMultiple Airlines
Deal found 2/21$12,296

Find flights from Iowa to Panama City within your budget

Customize your flight search to find flights from Iowa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

Iowa

Fly to

Panama City

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 3/11

7:45 am-6:38 pm

1 stop10h 53m

Panama City Tocumen Intl

Tue 3/18

3:40 pm-2:32 pm

2 stops22h 52m

$416

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Tue 3/25

7:26 pm-2:32 pm

2 stops19h 06m

Panama City Tocumen Intl

Mon 3/31

3:30 pm-5:53 pm

2 stops26h 23m

$506

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Fri 3/21

6:11 pm-12:15 pm

2 stops18h 04m

Panama City Tocumen Intl

Mon 3/24

3:30 pm-11:58 am

2 stops20h 28m

$518

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Tue 4/8

5:26 pm-2:14 pm

2 stops20h 48m

Panama City Tocumen Intl

Tue 4/15

3:20 pm-10:36 am

2 stops19h 16m

$526

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

6:13 pm-12:15 pm

2 stops18h 02m

Panama City Tocumen Intl

Sat 5/31

1:20 pm-11:13 am

2 stops21h 53m

$556

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

Fri 3/21

6:15 am-4:07 pm

1 stop9h 52m

Panama City Tocumen Intl

Mon 3/24

7:55 am-10:30 pm

1 stop14h 35m

$719

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Tue 3/25

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

Mon 3/31

2:20 pm-10:23 pm

1 stop8h 03m

$842

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 4/7

7:30 am-9:10 pm

2 stops13h 40m

Panama City Tocumen Intl

Sun 4/13

3:20 am-11:13 pm

3 stops19h 53m

$865

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 5/24

5:35 am-12:48 pm

1 stop7h 13m

Panama City Tocumen Intl

Sat 5/31

8:00 am-5:50 pm

1 stop9h 50m

$891

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Tue 4/8

8:00 am-12:10 am

2 stops16h 10m

Panama City Tocumen Intl

Mon 4/14

3:25 am-9:52 pm

2 stops18h 27m

$1,128

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/23

Showing 1-10 of 16 results
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Best time to book a flight from Iowa to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Panama City

Get recent, data-driven insights about flights from Iowa to Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Panama City?

Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to PTY?

Find hourly flight availability from Iowa to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

When flying from Iowa to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 23, 2025.
Read through reviews of airlines operating flights from Iowa to Panama City, such as Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good
8.0
Very good

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

8.0
Very good

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

8.0

Food

7.3

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Panama City from Iowa?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly into when you book flights from Iowa to Panama City.

  • What are the cheapest airlines to fly from Iowa to Panama City one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $173. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from Iowa to Panama City for a low price.

  • What are the most popular routes from Iowa to Panama City?

  • Can I find deals for flights from Iowa to Panama City that include hotel bookings?

    Yes. In addition to deals on Iowa to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Panama City.

  • Can I find deals for business class flights from Iowa to Panama City?

    Yes. Cheapflights offers flight deals from Iowa to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Iowa to Panama City (average of $478). Flying from Iowa to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Iowa to Panama City

Discover the top 3 airlines that operate flights from Iowa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$329Average$596FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$337Average$516FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$354Average$544FlexibilityNo cancel feeOn-time71%
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