HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$442+ Cheap flights from Buffalo (BUF) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Buffalo to Panama City with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$461
(Delta)

Popular in

March

Cheapest in

October

Average price

$780
Provider with most accurate pricing for Buffalo-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Panama City Tocumen Intl flights.
Search Deals
From Buffalo to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($9 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
Search Deals

Find flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/17:45 pmBUF - PTY
2 stops23h 52mUnited Airlines
Tue 4/83:20 pmPTY - BUF
2 stops17h 34mUnited Airlines
Deal found 3/25$442
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1012:20 pmBUF - PTY
1 stop8h 33mDelta
Sat 5/172:13 pmPTY - BUF
1 stop8h 40mDelta
Deal found 3/26$461
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/125:46 pmBUF - PTY
2 stops19h 29mAmerican Airlines
Sat 4/191:05 pmPTY - BUF
2 stops21h 56mAmerican Airlines
Deal found 3/27$768
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/111:24 amBUF - PTY
1 stop10h 03mMultiple Airlines
Tue 4/89:34 amPTY - BUF
2 stops23h 50mMultiple Airlines
Deal found 3/25$1,017
This Expedia deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/17:45 pmBUF - PTY
2 stops29h 25mAvianca
Mon 4/73:25 amPTY - BUF
2 stops38h 22mAvianca
Deal found 3/25$1,031
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:00 amBUF - PTY
1 stop8h 31mCopa Airlines
Tue 4/89:13 amPTY - BUF
1 stop8h 34mCopa Airlines
Deal found 3/25$1,655

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Buffalo

Fly to

Panama City

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 5/10

12:20 pm-7:53 pm

1 stop8h 33m

Panama City Tocumen Intl

Sat 5/17

2:13 pm-11:53 pm

1 stop8h 40m

$461

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 8/8

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Wed 8/13

3:20 pm-9:54 am

2 stops17h 34m

$502

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 4/12

5:46 pm-12:15 pm

2 stops19h 29m

Panama City Tocumen Intl

Sat 4/19

1:05 pm-12:01 pm

2 stops21h 56m

$768

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 5/10

6:45 am-12:10 am

2 stops18h 25m

Panama City Tocumen Intl

Fri 5/16

3:25 am-9:22 pm

2 stops16h 57m

$1,071

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 8/21

8:25 pm-10:10 am

2 stops14h 45m

Panama City Tocumen Intl

Sat 8/30

3:20 am-6:21 pm

2 stops14h 01m

$1,090

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Compare providers for flights from Buffalo to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*1 star
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars
SmartFaresPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama City

What is the cheapest month to book a flight from Buffalo to Panama City?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $478). Flying from Buffalo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PTY?

Find hourly flight availability from Buffalo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

It’s optimal to fly from Buffalo to Panama City in the afternoon. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight in the morning.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 28, 2025.
See what other customers who have flown with Delta, United Airlines and American Airlines from Buffalo to Panama City have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,300 reviews
Delta
8.0
Very good
7,897 reviews

Comfort

8.0

Crew

8.5

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to Panama City round-trip?

    Delta, at $461, was found to be the cheapest airline from Buffalo to Panama City.Alternate airlines to your destination round-trip include United Airlines and American Airlines. Delta is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $478). Flying from Buffalo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Buffalo to Panama City

Discover the top 2 airlines that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$421Average$609FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$455Average$623FlexibilityNo cancel feeOn-time69%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.