HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Ohio

$80+ Cheap flights from Knoxville (TYS) to Ohio

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CLE
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Ohio with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Ohio

Keep the following information in mind while searching for Knoxville to Ohio flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$172
(Mytrip)

One-way from

$80
(American Airlines)

Popular in

March

Cheapest in

February

Average price

$263
Provider with most accurate pricing for Knoxville McGhee Tyson-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Cleveland Hopkins Intl flights.
Search Deals
From Knoxville McGhee Tyson to Ohio
Search Deals
One-way flight from Knoxville McGhee Tyson to Ohio
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($60 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals

Find flight deals from Knoxville to Ohio

Cheapest flights from Knoxville to Ohio
Explore the most affordable flight options available from Knoxville to Ohio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:20 amTYS - DTW
1 stop18h 39mMultiple Airlines
Wed 4/97:27 pmDTW - TYS
1 stop17h 26mMultiple Airlines
Deal found 2/19$172
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:00 amTYS - CLE
1 stop13h 34mMultiple Airlines
Mon 3/248:06 pmCLE - TYS
1 stop27h 25mMultiple Airlines
Deal found 2/19$181
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:00 amTYS - CVG
1 stop17h 04mAllegiant Air
Mon 3/106:30 amCVG - TYS
1 stop8h 03mAllegiant Air
Deal found 2/19$189
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/126:00 amTYS - PIT
1 stop10h 36mMultiple Airlines
Sun 4/2712:02 pmPIT - TYS
1 stop26h 25mMultiple Airlines
Deal found 2/20$193
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/246:50 pmTYS - DTW
1 stop4h 32mAmerican Airlines
Thu 3/277:58 pmDTW - TYS
1 stop4h 05mAmerican Airlines
Deal found 2/19$199
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/75:30 amTYS - PIT
1 stop4h 22mDelta
Sat 5/106:00 amPIT - TYS
1 stop5h 33mDelta
Deal found 2/20$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1211:59 amTYS - CLE
1 stop6h 03mDelta
Wed 3/196:05 amCLE - TYS
1 stop6h 03mDelta
Deal found 2/19$199
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/187:50 amTYS - CMH
1 stop5h 38mDelta
Tue 3/256:07 pmCMH - TYS
1 stop3h 21mDelta
Deal found 2/19$199
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/197:15 amTYS - CMH
1 stop10h 10mMultiple Airlines
Sun 3/239:36 pmCMH - TYS
2 stops23h 37mMultiple Airlines
Deal found 2/20$213
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/285:30 amTYS - CVG
1 stop4h 54mDelta
Mon 9/15:55 pmCVG - TYS
1 stop5h 52mDelta
Deal found 2/19$219
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/75:50 amTYS - CLE
2 stops8h 57mUnited Airlines
Sun 5/115:54 pmCLE - TYS
1 stop4h 51mUnited Airlines
Deal found 2/20$220
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:18 amTYS - PIT
1 stop3h 19mAmerican Airlines
Sun 8/246:16 pmPIT - TYS
1 stop3h 19mAmerican Airlines
Deal found 2/20$229

Find flights from Knoxville to Ohio within your budget

Customize your flight search to find flights from Knoxville to Ohio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Knoxville

Fly to

Ohio

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 4/3

6:20 am-12:59 am

1 stop18h 39m

Detroit Metropolitan Wayne County

Wed 4/9

7:27 pm-12:53 pm

1 stop17h 26m

$172

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Thu 3/20

6:00 am-7:34 pm

1 stop13h 34m

Cleveland Hopkins Intl

Mon 3/24

8:06 pm-11:31 pm

1 stop27h 25m

$181

KnoxvilleCincinnati

TYS - CVG

TYSCVG

Knoxville McGhee Tyson

Thu 3/6

6:00 am-11:04 pm

1 stop17h 04m

Cincinnati Cinci./N. Kentucky

Mon 3/10

6:30 am-2:33 pm

1 stop8h 03m

$189

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Sat 4/12

6:00 am-4:36 pm

1 stop10h 36m

Pittsburgh

Sun 4/27

12:02 pm-2:27 pm

1 stop26h 25m

$193

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 3/24

6:50 pm-11:22 pm

1 stop4h 32m

Detroit Metropolitan Wayne County

Thu 3/27

7:58 pm-12:03 am

1 stop4h 05m

$199

KnoxvillePittsburgh

TYS - PIT

TYSPIT

Knoxville McGhee Tyson

Wed 5/7

5:30 am-9:52 am

1 stop4h 22m

Pittsburgh

Sat 5/10

6:00 am-11:33 am

1 stop5h 33m

$199

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 3/12

11:59 am-6:02 pm

1 stop6h 03m

Cleveland Hopkins Intl

Wed 3/19

6:05 am-12:08 pm

1 stop6h 03m

$199

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 3/18

7:50 am-1:28 pm

1 stop5h 38m

Columbus

Tue 3/25

6:07 pm-9:28 pm

1 stop3h 21m

$199

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 3/19

7:15 am-5:25 pm

1 stop10h 10m

Columbus

Sun 3/23

9:36 pm-9:13 pm

2 stops23h 37m

$213

KnoxvilleCleveland

TYS - CLE

TYSCLE

Knoxville McGhee Tyson

Wed 5/7

5:50 am-2:47 pm

2 stops8h 57m

Cleveland Hopkins Intl

Sun 5/11

5:54 pm-10:45 pm

1 stop4h 51m

$220

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Showing 1-10 of 39 results
1
2
3
4

Best time to book a flight from Knoxville to Ohio

Have a flexible travel schedule? Discover the best time to fly to Ohio from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Ohio

Get recent, data-driven insights about flights from Knoxville to Ohio including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Ohio?

Currently, April is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $250). Flying from Knoxville to Ohio in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to OH?

Find hourly flight availability from Knoxville to Ohio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Knoxville to Ohio, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Ohio by month

Plan your trip to Ohio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Ohio ranges from 2.3 - 3.8 inches per month. September is typically the wettest month, when rainfall can reach 3.8 in. February is typically the driest time to visit Ohio when rainfall is around 2.3 in.

Temperature in Ohio by month

Plan your trip to Ohio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Ohio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Ohio

Get insights into the airlines that provide service to Ohio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Ohio. Reviews last updated February 20, 2025.
To help decide which airline to fly from Knoxville to Ohio, see what other customers have to say about Delta, United Airlines and Allegiant Air. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.3
Good
765 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Ohio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Ohio?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Ohio. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Ohio one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $80. Allegiant Air flights start at $99 while deals on Delta start at $200 one-way.

  • What are the most popular routes from Knoxville to Ohio?

    The most popular flight routes from Knoxville to Ohio are Knoxville McGhee Tyson - Detroit Metropolitan Wayne County, Knoxville McGhee Tyson - Cleveland Hopkins Intl and Knoxville McGhee Tyson - Columbus.

  • Can I find deals for flights from Knoxville to Ohio that include hotel bookings?

    Yes. In addition to deals on Knoxville to Ohio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Ohio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Ohio.

  • Can I find deals for business class flights from Knoxville to Ohio?

    Yes. Cheapflights offers flight deals from Knoxville to Ohio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Ohio?

    Currently, April is the cheapest month in which you can book a flight from Knoxville to Ohio (average of $250). Flying from Knoxville to Ohio in June is currently the most expensive (average of $290). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Ohio

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to LaGuardia flights
Nashville to Orlando flights
Nashville to Las Vegas flights
Nashville to Miami flights
Nashville to Los Angeles flights
Nashville to John F Kennedy Intl flights
Nashville to Denver flights
Nashville to Seattle flights
Nashville to Newark flights
Nashville to Fort Lauderdale flights
Nashville to Dallas/Fort Worth flights
Nashville to O'Hare Intl flights
Nashville to Sky Harbor Intl flights
Memphis to Las Vegas flights
Nashville to Reagan-National flights
Memphis to LaGuardia flights
Nashville to Tampa flights
Memphis to Hobby flights
Memphis to Orlando flights
Nashville to San Francisco flights
Nashville to Dulles Intl flights
Nashville to Baltimore flights
Memphis to Miami flights
Nashville to Salt Lake City flights
Nashville to Austin flights
Memphis to John F Kennedy Intl flights
Memphis to Los Angeles flights
Memphis to O'Hare Intl flights
Nashville to Boston flights
Memphis to Newark flights
Memphis to Denver flights
Nashville to Hobby flights
Memphis to Dallas/Fort Worth flights
Knoxville to LaGuardia flights
Memphis to George Bush Intcntl flights
Nashville to Honolulu flights
Knoxville to Hobby flights
Chattanooga to Orlando flights
Knoxville to Denver flights
Nashville to George Bush Intcntl flights
Nashville to Philadelphia flights
Memphis to Atlanta flights
Memphis to Sky Harbor Intl flights
Nashville to Portland flights
Knoxville to Dulles Intl flights
Knoxville to George Bush Intcntl flights
Memphis to Seattle flights
Knoxville to Dallas/Fort Worth flights
Nashville to Ontario flights
Knoxville to John F Kennedy Intl flights

Top 3 airlines flying from Knoxville to Ohio

Discover the top 3 airlines that operate flights from Knoxville to Ohio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$304FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$444FlexibilityNo cancel feeOn-time69%
DeltaCheapest$218Average$310FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.