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$100+ Cheap flights from St. Louis to Panama City, FL (STL - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ECP
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheapflights Tip: The best prices from Lambert-St Louis to Panama City NW Florida Beaches are usually found in September or July, booked 90 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from St. Louis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$209
(American Airlines)

One-way from

$100
(American Airlines)

Popular in

November

Cheapest in

September

Average price

$405

Good round-trip deal

$405 or less

Good one-way deal

$332 or less
Provider with most accurate pricing for Lambert-St Louis-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Panama City NW Florida Beaches flights.
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From Lambert-St Louis to Panama City NW Florida Beaches
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One-way flight from Lambert-St Louis to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Lambert-St Louis to Panama City NW Florida Beaches.
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Price to beat on a one-way flight from Lambert-St Louis to Panama City NW Florida Beaches.
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Find flight deals from St. Louis to Panama City

Cheapest flights from St. Louis to Panama City
Explore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/144:28 pmSTL - ECP
1 stop7h 25mAmerican Airlines
Sat 7/197:28 pmECP - STL
1 stop4h 46mAmerican Airlines
Deal found 4/27$209
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/315:00 pmSTL - ECP
1 stop4h 19mDelta
Thu 6/51:59 pmECP - STL
1 stop6h 40mDelta
Deal found 4/28$309
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2811:22 amSTL - ECP
1 stop4h 58mUnited Airlines
Mon 6/28:55 amECP - STL
1 stop7h 58mUnited Airlines
Deal found 4/27$315
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/67:30 amSTL - ECP
Nonstop1h 45mSouthwest
Wed 6/116:05 amECP - STL
Nonstop1h 50mSouthwest
Deal found 4/28$322

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from St. Louis to Panama City that are best for you.

Fly from

St. Louis

Fly to

Panama City

Route

Depart

Return

Price

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 6/9

4:37 pm-11:49 pm

1 stop7h 12m

Panama City NW Florida Beaches

Wed 6/18

7:02 pm-11:59 pm

1 stop4h 57m

$199

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 6/2

3:45 pm-9:50 pm

1 stop6h 05m

Panama City NW Florida Beaches

Wed 6/11

6:05 am-7:55 am

Nonstop1h 50m

$305

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Sat 5/31

5:00 pm-9:19 pm

1 stop4h 19m

Panama City NW Florida Beaches

Thu 6/5

1:59 pm-8:39 pm

1 stop6h 40m

$309

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 5/28

11:22 am-4:20 pm

1 stop4h 58m

Panama City NW Florida Beaches

Mon 6/2

8:55 am-4:53 pm

1 stop7h 58m

$315

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Wed 7/30

4:45 pm-11:53 pm

1 stop7h 08m

$100

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 7/28

10:46 am-4:20 pm

1 stop5h 34m

$105

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Tue 6/3

6:50 pm-8:35 pm

Nonstop1h 45m

$139

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 6/2

8:10 am-7:11 pm

2 stops11h 01m

$167

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Compare providers for flights from St. Louis to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Panama City in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Panama City

How far ahead should I book a flight from St. Louis to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Panama City. Price data was last updated on April 25, 2025.

The price you pay for your flight from St. Louis to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 90 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Panama City, Florida (average of $346). Flying from St. Louis to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to ECP?

Find hourly flight availability from St. Louis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

It’s typically best to fly out from St. Louis to Panama City, Florida in the evening. Doing so could potentially save you 25% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from St. Louis to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Panama City. Price data was last updated on March 30, 2025.

Travelers seeking maximum savings on their St. Louis to Panama City, Florida flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 29, 2025.
To help decide which airline to fly from St. Louis to Panama City, see what other customers have to say about Southwest, Delta and United Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this St. Louis to Panama City, Florida flight route?

    The Lambert-St Louis to Panama City NW Florida Beaches flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from St. Louis to Panama City, Florida round-trip?

    Our cheapest airline available from St. Louis to Panama City, Florida is American Airlines. Our recent data shows that you can find tickets from as low as $209 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $309 and $315 round-trip. American Airlines is priced at 49% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from St. Louis to Panama City, Florida one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $100. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from St. Louis to Panama City, Florida for a low price.

  • What are the cheapest flights from St. Louis to Panama City, Florida?

    While on average a flight from St. Louis to Panama City, Florida is generally $441, our data shows the cheapest flight currently is $239. When looking at the most popular route, (Lambert-St Louis - Panama City NW Florida Beaches), you can expect to pay $313 for that flight.

  • Can I find deals for flights from St. Louis to Panama City that include hotel bookings?

    Yes. In addition to deals on St. Louis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama City.

  • Can I find deals for business class flights from St. Louis to Panama City?

    Yes. Cheapflights offers flight deals from St. Louis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from St. Louis to Panama City, Florida (average of $346). Flying from St. Louis to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from St. Louis to Panama City

Discover the top 5 airlines that operate flights from St. Louis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$192Average$233FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$223Average$360FlexibilityNo cancel feeOn-time71%
DeltaCheapest$278Average$404FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$282Average$435FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$347Average$450FlexibilityNo cancel feeOn-time63%

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