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$128+ Cheap flights from South Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from South Carolina to Panama City

Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$217
(Delta)

One-way from

$128
(American Airlines)

Popular in

May

Cheapest in

September

Average price

$452
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
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From South Carolina to Panama City NW Florida Beaches
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One-way flight from South Carolina to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 23% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/253:59 pmCHS - ECP
1 stop4h 42mDelta
Wed 4/21:54 pmECP - CHS
1 stop6h 16mDelta
Deal found 2/22$217
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/256:00 amCHS - ECP
2 stops9h 01mAmerican Airlines
Wed 4/22:41 pmECP - CHS
1 stop6h 36mAmerican Airlines
Deal found 2/22$222
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/125:05 pmGSP - ECP
1 stop3h 30mDelta
Wed 5/147:45 amECP - GSP
1 stop6h 11mDelta
Deal found 2/21$255
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/166:00 amCLT - ECP
1 stop3h 26mDelta
Thu 4/246:00 amECP - CLT
1 stop3h 25mDelta
Deal found 2/21$293
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/135:45 pmCLT - ECP
1 stop5h 50mSouthwest
Tue 3/189:00 amECP - CLT
2 stops11h 50mSouthwest
Deal found 2/21$298
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/105:20 pmMYR - ECP
1 stop5h 30mSouthwest
Wed 4/162:55 pmECP - MYR
1 stop5h 40mSouthwest
Deal found 2/22$311
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/13:10 pmCLT - ECP
Nonstop1h 43mAmerican Airlines
Wed 4/92:27 pmECP - CLT
Nonstop1h 37mAmerican Airlines
Deal found 2/22$313
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/235:40 amCAE - ECP
1 stop3h 51mDelta
Sat 3/296:51 pmECP - CAE
1 stop3h 47mDelta
Deal found 2/21$338
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/106:00 amMYR - ECP
1 stop3h 31mDelta
Wed 4/166:00 amECP - MYR
1 stop3h 37mDelta
Deal found 2/22$377
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/245:25 pmCHS - ECP
1 stop5h 40mSouthwest
Mon 4/286:25 amECP - CHS
1 stop4h 30mSouthwest
Deal found 2/22$411
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:36 amCLT - ECP
2 stops14h 33mUnited Airlines
Wed 4/94:58 pmECP - CLT
2 stops23h 54mUnited Airlines
Deal found 2/22$526
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:40 amGSP - ECP
1 stop3h 48mAmerican Airlines
Sat 5/104:25 pmECP - GSP
1 stop3h 52mAmerican Airlines
Deal found 2/22$554

Find flights from South Carolina to Panama City within your budget

Customize your flight search to find flights from South Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

South Carolina

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 3/25

3:59 pm-7:41 pm

1 stop4h 42m

Panama City NW Florida Beaches

Wed 4/2

1:54 pm-9:10 pm

1 stop6h 16m

$217

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 3/25

6:00 am-2:01 pm

2 stops9h 01m

Panama City NW Florida Beaches

Wed 4/2

2:41 pm-10:17 pm

1 stop6h 36m

$222

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Mon 5/12

5:05 pm-7:35 pm

1 stop3h 30m

Panama City NW Florida Beaches

Wed 5/14

7:45 am-2:56 pm

1 stop6h 11m

$255

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Wed 4/16

6:00 am-8:26 am

1 stop3h 26m

Panama City NW Florida Beaches

Thu 4/24

6:00 am-10:25 am

1 stop3h 25m

$293

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Thu 3/13

5:45 pm-10:35 pm

1 stop5h 50m

Panama City NW Florida Beaches

Tue 3/18

9:00 am-9:50 pm

2 stops11h 50m

$298

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 4/10

5:20 pm-9:50 pm

1 stop5h 30m

Panama City NW Florida Beaches

Wed 4/16

2:55 pm-9:35 pm

1 stop5h 40m

$311

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Tue 4/1

3:10 pm-3:53 pm

Nonstop1h 43m

Panama City NW Florida Beaches

Wed 4/9

2:27 pm-5:04 pm

Nonstop1h 37m

$313

ColumbiaPanama City

CAE - ECP

CAEECP

Columbia Metropolitan

Sun 3/23

5:40 am-8:31 am

1 stop3h 51m

Panama City NW Florida Beaches

Sat 3/29

6:51 pm-11:38 pm

1 stop3h 47m

$338

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Thu 4/10

6:00 am-8:31 am

1 stop3h 31m

Panama City NW Florida Beaches

Wed 4/16

6:00 am-10:37 am

1 stop3h 37m

$377

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 4/24

5:25 pm-10:05 pm

1 stop5h 40m

Panama City NW Florida Beaches

Mon 4/28

6:25 am-11:55 am

1 stop4h 30m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 28 results
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Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Panama City

Get recent, data-driven insights about flights from South Carolina to Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ECP?

Find hourly flight availability from South Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Panama City, Florida as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 23, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Panama City. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Comfort

8.1

Food

7.1

Crew

8.7

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,395 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Comfort

8.1

Food

7.1

Crew

8.7

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Comfort

8.1

Food

7.1

Crew

8.7

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Comfort

8.1

Food

7.1

Crew

8.7

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,395 reviews

Boarding

8.2

Comfort

8.1

Food

7.1

Crew

8.7

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Carolina?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Carolina to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • What are the cheapest airlines to fly from South Carolina to Panama City, Florida one-way?

    $128 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $154 and $198, respectively.

  • What are the most popular routes from South Carolina to Panama City, Florida?

    While some choose either Greenville - Panama City NW Florida Beaches or Charleston - Panama City NW Florida Beaches, Charlotte Douglas - Panama City NW Florida Beaches is the most popular route from South Carolina to Panama City, Florida.

  • Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.

  • Can I find deals for business class flights from South Carolina to Panama City?

    Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
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Alternative routes for South Carolina to Panama City

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Top 3 airlines flying from South Carolina to Panama City

Discover the top 3 airlines that operate flights from South Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$102Average$396FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$399FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$376FlexibilityNo cancel feeOn-time63%
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