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Panama City

$115+ Cheap flights from South Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
huhti 9 — huhti 161
ke 4/9
ke 4/16
1 adult, Economy
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Cheap flight deals from South Carolina to Panama City

Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated huhtikuu 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$219
(Delta)

One-way from

$115
(Delta)

Popular in

May

Cheapest in

September

Average price

$355
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
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From South Carolina to Panama City NW Florida Beaches
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One-way flight from South Carolina to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 19% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on huhtikuu 4, 2025.

This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 8/134:00 pmAGS - ECP
1 stop4h 36mDelta
ti 8/196:00 amECP - AGS
1 stop4h 00mDelta
Deal found 4/3$219
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 5/75:40 amCLT - ECP
1 stop3h 36mDelta
su 5/119:12 amECP - CLT
1 stop4h 44mDelta
Deal found 4/3$253
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 9/263:42 pmGSP - ECP
1 stop4h 56mDelta
ma 9/294:10 pmECP - GSP
1 stop4h 11mDelta
Deal found 4/2$268
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ke 9/310:25 amGSP - ECP
1 stop6h 15mSouthwest
su 9/78:00 amECP - GSP
2 stops13h 05mSouthwest
Deal found 4/2$292
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/296:25 amCLT - ECP
1 stop5h 25mSouthwest
la 5/312:05 pmECP - CLT
2 stops8h 15mSouthwest
Deal found 4/3$298
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 6/148:30 pmCHS - ECP
1 stop4h 19mAmerican Airlines
ti 6/175:26 amECP - CHS
1 stop3h 57mAmerican Airlines
Deal found 4/3$302
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 7/256:16 pmMYR - ECP
1 stop6h 37mAmerican Airlines
ma 7/286:55 pmECP - MYR
1 stop4h 00mAmerican Airlines
Deal found 4/3$307
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 7/259:12 amCLT - ECP
Nonstop1h 56mAmerican Airlines
ma 8/46:55 pmECP - CLT
Nonstop1h 50mAmerican Airlines
Deal found 4/4$342
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti 4/155:06 pmCAE - ECP
1 stop5h 47mDelta
la 4/197:30 amECP - CAE
1 stop5h 25mDelta
Deal found 4/4$344
This Southwest deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pe 7/257:10 pmMYR - ECP
1 stop4h 05mSouthwest
ma 7/286:15 amECP - MYR
2 stops10h 00mSouthwest
Deal found 4/3$362
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
la 4/191:01 pmGSP - ECP
1 stop4h 22mAmerican Airlines
ke 4/234:55 pmECP - GSP
1 stop5h 43mAmerican Airlines
Deal found 4/4$363
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
su 4/205:35 amCHS - ECP
1 stop3h 51mDelta
pe 4/256:38 pmECP - CHS
1 stop4h 20mDelta
Deal found 4/4$377

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated huhtikuu 4, 2025.
Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

South Carolina

Fly to

Panama City

Route

Depart

Return

Price

AugustaPanama City

AGS - ECP

AGSECP

Augusta Bush Field

ke 8/13

4:00 pm-7:36 pm

1 stop4h 36m

Panama City NW Florida Beaches

ti 8/19

6:00 am-11:00 am

1 stop4h 00m

$219

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

ke 5/7

5:40 am-8:16 am

1 stop3h 36m

Panama City NW Florida Beaches

su 5/11

9:12 am-2:56 pm

1 stop4h 44m

$253

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

pe 9/26

3:42 pm-7:38 pm

1 stop4h 56m

Panama City NW Florida Beaches

ma 9/29

4:10 pm-9:21 pm

1 stop4h 11m

$268

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

ke 9/3

10:25 am-3:40 pm

1 stop6h 15m

Panama City NW Florida Beaches

su 9/7

8:00 am-10:05 pm

2 stops13h 05m

$292

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

ti 4/29

6:25 am-10:50 am

1 stop5h 25m

Panama City NW Florida Beaches

la 5/3

12:05 pm-9:20 pm

2 stops8h 15m

$298

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

la 6/14

8:30 pm-11:49 pm

1 stop4h 19m

Panama City NW Florida Beaches

ti 6/17

5:26 am-10:23 am

1 stop3h 57m

$302

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

pe 7/25

6:16 pm-11:53 pm

1 stop6h 37m

Panama City NW Florida Beaches

ma 7/28

6:55 pm-11:55 pm

1 stop4h 00m

$307

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

to 6/26

1:18 pm-2:00 pm

Nonstop1h 42m

Panama City NW Florida Beaches

su 6/29

7:02 pm-9:50 pm

Nonstop1h 48m

$343

ColumbiaPanama City

CAE - ECP

CAEECP

Columbia Metropolitan

ti 4/15

5:06 pm-9:53 pm

1 stop5h 47m

Panama City NW Florida Beaches

la 4/19

7:30 am-1:55 pm

1 stop5h 25m

$344

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

pe 7/25

7:10 pm-10:15 pm

1 stop4h 05m

Panama City NW Florida Beaches

ma 7/28

6:15 am-5:15 pm

2 stops10h 00m

$362

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/4

Showing 1-10 of 30 results
1
2
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Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Panama City

What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ECP?

Find hourly flight availability from South Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated huhtikuu 4, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Panama City, Florida as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated huhtikuu 4, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Panama City. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,276 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,276 reviews
Southwest
8.0
Very good
4,276 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,901 reviews
Southwest
8.0
Very good
4,276 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,621 reviews
Southwest
8.0
Very good
4,276 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,276 reviews

Entertainment

7.6

Comfort

8.0

Crew

8.6

Boarding

8.2

Overall

8.0

Food

7.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Carolina?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Carolina to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • What are the cheapest airlines to fly from South Carolina to Panama City, Florida one-way?

    $115 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on Southwest and American Airlines, with prices starting from $122 and $364, respectively.

  • What are the most popular routes from South Carolina to Panama City, Florida?

    While some choose either Charleston - Panama City NW Florida Beaches or Columbia Metropolitan - Panama City NW Florida Beaches, Charlotte Douglas - Panama City NW Florida Beaches is the most popular route from South Carolina to Panama City, Florida.

  • Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.

  • Can I find deals for business class flights from South Carolina to Panama City?

    Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
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Top 3 airlines flying from South Carolina to Panama City

Discover the top 3 airlines that operate flights from South Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated huhtikuu 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$102Average$401FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$351FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$411FlexibilityNo cancel feeOn-time63%

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