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Panama City

$109+ Cheap flights from Missouri to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — ECP
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Missouri to Panama City

Keep the following information in mind while searching for Missouri to Panama City flight deals. Data was last updated February 22, 2025.

Round-trip from

$217
(Delta)

One-way from

$109
(Delta)

Good round-trip deal

$405 or less
From Missouri to Panama City NW Florida Beaches
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One-way flight from Missouri to Panama City NW Florida Beaches
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Price to beat on a round-trip flight from Missouri to Panama City NW Florida Beaches.
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Find flight deals from Missouri to Panama City

Cheapest flights from Missouri to Panama City
Explore the most affordable flight options available from Missouri to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/95:30 pmMCI - ECP
1 stop5h 35mDelta
Tue 4/156:38 pmECP - MCI
1 stop5h 21mDelta
Deal found 2/21$217
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/95:37 amMCI - ECP
2 stops7h 53mAmerican Airlines
Tue 4/153:38 pmECP - MCI
1 stop6h 26mAmerican Airlines
Deal found 2/21$222
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/115:00 pmMCI - ECP
1 stop5h 05mSouthwest
Mon 4/144:40 pmECP - MCI
1 stop6h 15mSouthwest
Deal found 2/21$237
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/214:55 pmSGF - ECP
1 stop4h 57mUnited Airlines
Fri 3/289:00 amECP - SGF
1 stop7h 15mUnited Airlines
Deal found 2/21$250
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/92:57 pmMCI - ECP
1 stop5h 12mUnited Airlines
Tue 4/152:25 pmECP - MCI
1 stop7h 35mUnited Airlines
Deal found 2/22$287
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/63:05 pmSTL - ECP
Nonstop1h 45mSouthwest
Mon 3/1010:10 amECP - STL
Nonstop1h 55mSouthwest
Deal found 2/20$313
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/114:30 pmSGF - ECP
1 stop4h 02mAmerican Airlines
Sat 3/1511:02 amECP - SGF
1 stop5h 25mAmerican Airlines
Deal found 2/21$339
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/117:12 pmSTL - ECP
1 stop3h 53mDelta
Tue 4/156:00 amECP - STL
1 stop5h 45mDelta
Deal found 2/21$353
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/246:00 amSTL - ECP
2 stops8h 01mAmerican Airlines
Mon 3/313:42 pmECP - STL
1 stop7h 02mAmerican Airlines
Deal found 2/22$373
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/115:35 pmSTL - ECP
2 stops20h 18mUnited Airlines
Tue 4/156:15 amECP - STL
2 stops8h 27mUnited Airlines
Deal found 2/21$449
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/153:29 pmSGF - ECP
1 stop4h 12mDelta
Fri 3/216:00 amECP - SGF
1 stop5h 25mDelta
Deal found 2/22$719

Find flights from Missouri to Panama City within your budget

Customize your flight search to find flights from Missouri to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Missouri

Fly to

Panama City

Route

Depart

Return

Price

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 4/9

5:30 pm-11:05 pm

1 stop5h 35m

Panama City NW Florida Beaches

Tue 4/15

6:38 pm-11:59 pm

1 stop5h 21m

$217

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 4/9

5:37 am-1:30 pm

2 stops7h 53m

Panama City NW Florida Beaches

Tue 4/15

3:38 pm-10:04 pm

1 stop6h 26m

$222

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Fri 4/11

5:00 pm-10:05 pm

1 stop5h 05m

Panama City NW Florida Beaches

Mon 4/14

4:40 pm-10:55 pm

1 stop6h 15m

$237

SpringfieldPanama City

SGF - ECP

SGFECP

Springfield-Branson

Fri 3/21

4:55 pm-9:52 pm

1 stop4h 57m

Panama City NW Florida Beaches

Fri 3/28

9:00 am-4:15 pm

1 stop7h 15m

$250

Kansas CityPanama City

MCI - ECP

MCIECP

Kansas City

Wed 4/9

2:57 pm-8:09 pm

1 stop5h 12m

Panama City NW Florida Beaches

Tue 4/15

2:25 pm-10:00 pm

1 stop7h 35m

$287

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Thu 3/6

3:05 pm-4:50 pm

Nonstop1h 45m

Panama City NW Florida Beaches

Mon 3/10

10:10 am-12:05 pm

Nonstop1h 55m

$313

SpringfieldPanama City

SGF - ECP

SGFECP

Springfield-Branson

Tue 3/11

4:30 pm-8:32 pm

1 stop4h 02m

Panama City NW Florida Beaches

Sat 3/15

11:02 am-4:27 pm

1 stop5h 25m

$339

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Fri 4/11

7:12 pm-11:05 pm

1 stop3h 53m

Panama City NW Florida Beaches

Tue 4/15

6:00 am-11:45 am

1 stop5h 45m

$353

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Mon 3/24

6:00 am-2:01 pm

2 stops8h 01m

Panama City NW Florida Beaches

Mon 3/31

3:42 pm-10:44 pm

1 stop7h 02m

$373

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

Fri 4/11

5:35 pm-1:53 pm

2 stops20h 18m

Panama City NW Florida Beaches

Tue 4/15

6:15 am-2:42 pm

2 stops8h 27m

$449

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 19 results
1
2

Best time to book a flight from Missouri to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Missouri to Panama City

Get recent, data-driven insights about flights from Missouri to Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Missouri to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Missouri to Panama City, Florida (average of $346). Flying from Missouri to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to ECP?

Find hourly flight availability from Missouri to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

When flying from Missouri to Panama City, Florida, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated February 22, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Missouri to Panama City. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,396 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Comfort

8.1

Crew

8.7

Food

7.1

Entertainment

7.6

Overall

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Missouri?

    For a flight from Missouri to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city.

  • What are the cheapest airlines to fly from Missouri to Panama City, Florida one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $109. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Missouri to Panama City, Florida for a low price.

  • What are the most popular routes from Missouri to Panama City, Florida?

    When deciding which route to take from Missouri to Panama City, Florida consider Kansas City - Panama City NW Florida Beaches, Lambert-St Louis - Panama City NW Florida Beaches or Springfield-Branson - Panama City NW Florida Beaches as they are the most popular.

  • What are the cheapest flights from Missouri to Panama City, Florida?

    Looking for the cheapest flight from Missouri to Panama City, Florida? While on average our users pay $493, our data indicates the cheapest price to be $353. The most popular route (Kansas City - Panama City NW Florida Beaches), is priced around $217.

  • Can I find deals for flights from Missouri to Panama City that include hotel bookings?

    Yes. In addition to deals on Missouri to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Panama City.

  • Can I find deals for business class flights from Missouri to Panama City?

    Yes. Cheapflights offers flight deals from Missouri to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Panama City, Florida (average of $346). Flying from Missouri to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 5 airlines flying from Missouri to Panama City

Discover the top 5 airlines that operate flights from Missouri to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$186Average$394FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$192Average$231FlexibilityNo cancel feeOn-time88%
American AirlinesCheapest$208Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$304Average$478FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$316Average$475FlexibilityNo cancel feeOn-time63%
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