What are the cheapest airlines flying from Knoxville to Panama City, Florida round-trip?

Our cheapest airline available from Knoxville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $389 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $436 and $528 round-trip. You may be able to fly from Knoxville to Panama City, Florida for 34% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Knoxville to Panama City, Florida one-way?

The cheapest airlines for a one-way flight from Knoxville to Panama City, Florida are Delta ($279), American Airlines ($478), and United Airlines ($664).

What is the cheapest day to fly from Knoxville to Panama City, Florida?

Travelers seeking maximum savings on their Knoxville to Panama City, Florida flight should consider departing on Saturday afternoons when fares are most often at their lowest. Thursday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What is the cheapest day to fly round-trip from Knoxville to Panama City, Florida?

Friday flights are found to be more expensive to fly from Knoxville to Panama City, Florida. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Panama City, Florida.

How far in advance should I book a flight from Knoxville to Panama City, Florida?

Users have found that booking a flight from Knoxville to Panama City, Florida at least 25 days early can save you up to 76% on average compared to booking a flight this week. If booking 25 days before your flight isn’t an option for you, users have found flights from Knoxville to Panama City, Florida for as little as $608 when booking for a departure date within the next two weeks. You can also check prices now. Some users have found airline tickets as low as $723 for flights departing within the next 3 days.

What is the cheapest month to fly from Knoxville to Panama City, Florida?

Flights from Knoxville to Panama City, Florida lean towards being more expensive in March. Prices are generally better when you fly from Knoxville to Panama City, Florida in August, with the cheapest ticket starting at $358.

Most accurate provider : When it comes to deals on Knoxville-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Panama City, Florida flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Knoxville-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Knoxville to Panama City that include hotel bookings?

Yes. In addition to deals on Knoxville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Knoxville to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama City.

Can I find deals for business class flights from Knoxville to Panama City?

Yes. Cheapflights offers flight deals from Knoxville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$279+ Flights from Knoxville to Panama City, FL

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1. Tell us where you want to go

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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The best prices from Knoxville McGhee Tyson to Panama City NW Florida Beaches are usually found in August or September, booked 86 days in advance, depart on a Tuesday or Friday and return on a Tuesday

Cheap flight deals from Knoxville to Panama City

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$389 (Delta)
One-way from	$279 (Delta)
Popular in	March
Cheapest in	August
Average price	$618

Provider with most accurate pricing for Knoxville McGhee Tyson-Panama City NW Florida Beaches flight deals.

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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Panama City NW Florida Beaches flights.

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From Knoxville McGhee Tyson to Panama City NW Florida Beaches

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One-way flight from Knoxville McGhee Tyson to Panama City NW Florida Beaches

Search Deals

Highest demand for flights based on searches. 26% potential increase in price ($215 potential increase over avg. RT price).

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Cheapest flight prices on average. 8% potential price decrease ($49 potential savings vs. average RT price).

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Average for round-trip flights in February 2025

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Find flight deals from Knoxville to Panama City

Cheapest flights from Knoxville to Panama City
Explore the most affordable flight options available from Knoxville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Wed 4/27:23 pmTYS - ECP

1 stop4h 41mDelta

Sun 4/66:50 pmECP - TYS

1 stop3h 52mDelta

Deal found 2/19

$389

Sat 4/55:15 amTYS - ECP

2 stops12h 08mAmerican Airlines

Tue 4/811:05 amECP - TYS

1 stop9h 43mAmerican Airlines

Deal found 2/19

$436

Mon 4/77:00 amTYS - ECP

1 stop14h 09mUnited Airlines

Fri 4/114:58 pmECP - TYS

2 stops28h 24mUnited Airlines

Deal found 2/19

$528

Best flights from Knoxville to Panama City
Discover carefully curated flight deals from Knoxville to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2025.

Wed 4/27:23 pmTYS - ECP

1 stop4h 41mDelta

Sun 4/66:50 pmECP - TYS

1 stop3h 52mDelta

Deal found 2/19

$389

Sat 4/55:15 amTYS - ECP

2 stops12h 08mAmerican Airlines

Tue 4/811:05 amECP - TYS

1 stop9h 43mAmerican Airlines

Deal found 2/19

$436

Mon 4/77:00 amTYS - ECP

1 stop14h 09mUnited Airlines

Fri 4/114:58 pmECP - TYS

2 stops28h 24mUnited Airlines

Deal found 2/19

$528

Last-minute flights from Knoxville to Panama City
Discover last-minute flight deals from Knoxville to Panama City. Data last updated February 20, 2025 and is based on user searches.

Wed 3/512:46 pmTYS - ECP

1 stop3h 43mAmerican Airlines

Sat 5/242:38 pmECP - TYS

1 stop5h 40mAmerican Airlines

Deal found 2/19

$499

Wed 3/55:35 pmTYS - ECP

2 stops19h 59mUnited Airlines

Sat 5/245:07 pmECP - TYS

2 stops16h 02mUnited Airlines

Deal found 2/19

$545

Thu 3/135:45 amTYS - ECP

1 stop5h 32mDelta

Wed 3/199:18 amECP - TYS

1 stop3h 32mDelta

Deal found 2/18

$419

One-way flights from Knoxville to Panama City
Search for one-way flight options from Knoxville to Panama City. Find affordable one-way fares based on user searches. Data last updated February 20, 2025.

Mon 3/172:35 pmTYS - ECP

1 stop6h 06mDelta

Deal found 2/19

$279

Thu 2/277:35 amTYS - ECP

2 stops7h 17mAmerican Airlines

Deal found 2/19

$478

Thu 2/277:00 amTYS - ECP

3 stops13h 57mUnited Airlines

Deal found 2/20

$664

Find flights from Knoxville to Panama City within your budget

Fly from

Fly to

Route

Depart

Return

Price

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Wed 4/2

7:23 pm-11:04 pm

1 stop4h 41m

Panama City NW Florida Beaches

Sun 4/6

6:50 pm-11:42 pm

1 stop3h 52m

$389

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Sat 4/5

5:15 am-4:23 pm

2 stops12h 08m

Panama City NW Florida Beaches

Tue 4/8

11:05 am-9:48 pm

1 stop9h 43m

$436

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Mon 4/7

7:00 am-8:09 pm

1 stop14h 09m

Panama City NW Florida Beaches

Fri 4/11

4:58 pm-10:22 pm

2 stops28h 24m

$528

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Mon 3/17

2:35 pm-7:41 pm

1 stop6h 06m

$279

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Thu 2/27

7:35 am-1:52 pm

2 stops7h 17m

$478

KnoxvillePanama City

TYS - ECP

TYSECP

Knoxville McGhee Tyson

Thu 2/27

7:00 am-7:57 pm

3 stops13h 57m

$664

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/19

Compare providers for flights from Knoxville to Panama City

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Panama City in February.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Knoxville-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Panama City, Florida flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Knoxville-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Knoxville with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Panama City

Get recent, data-driven insights about flights from Knoxville to Panama City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Knoxville to Panama City, Florida?

The price you pay for your flight from Knoxville to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Knoxville to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Panama City, Florida (average of $346). Flying from Knoxville to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to ECP?

It’s typically best to fly out from Knoxville to Panama City, Florida in the morning. Doing so could potentially save you 11% on the flight price compared to flying at noon, which is usually more expensive.

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Delta

8.0

Very good

8,219 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

United Airlines

7.4

Good

8,765 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

8,219 reviews

Reviews

1 / 20

2.0

Mediocre

Joseph,Aug 2023

MSP - MCO

Related info for your journey

What are the cheapest airlines flying from Knoxville to Panama City, Florida round-trip?
Our cheapest airline available from Knoxville to Panama City, Florida is Delta. Our recent data shows that you can find tickets from as low as $389 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $436 and $528 round-trip. You may be able to fly from Knoxville to Panama City, Florida for 34% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Knoxville to Panama City, Florida one-way?
The cheapest airlines for a one-way flight from Knoxville to Panama City, Florida are Delta ($279), American Airlines ($478), and United Airlines ($664).
Can I find deals for flights from Knoxville to Panama City that include hotel bookings?
Yes. In addition to deals on Knoxville to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Knoxville to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Panama City.
Can I find deals for business class flights from Knoxville to Panama City?
Yes. Cheapflights offers flight deals from Knoxville to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Knoxville to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Panama City, Florida (average of $346). Flying from Knoxville to Panama City, Florida in March is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 2 airlines flying from Knoxville to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$358	Average$535	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$398	Average$595	FlexibilityNo cancel fee	On-time71%

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$279+ Cheap flights from Knoxville to Panama City, FL (TYS - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Knoxville to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

The best prices from Knoxville McGhee Tyson to Panama City NW Florida Beaches are usually found in August or September, booked 86 days in advance, depart on a Tuesday or Friday and return on a Tuesday

Cheap flight deals from Knoxville to Panama City

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Knoxville to Panama City

Cheapest flights from Knoxville to Panama CityExplore the most affordable flight options available from Knoxville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Explore the most affordable flight options available from Knoxville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

Find flights from Knoxville to Panama City within your budget

Compare providers for flights from Knoxville to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Panama City in February.

Best time to book a flight from Knoxville to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Knoxville with our price prediction graph.

Travel insights for flights from Knoxville to Panama City

Get recent, data-driven insights about flights from Knoxville to Panama City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Knoxville to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Panama City. Price data was last updated on February 14, 2025.

What is the cheapest month to book a flight from Knoxville to Panama City, Florida?

What is the cheapest time of day to fly from TYS to ECP?

Find hourly flight availability from Knoxville to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Knoxville to Panama City, Florida round-trip?

What are the cheapest airlines to fly from Knoxville to Panama City, Florida one-way?

Can I find deals for flights from Knoxville to Panama City that include hotel bookings?

How can I find direct flights from Knoxville to Panama City?

Can I find deals for business class flights from Knoxville to Panama City?

What is the cheapest month to book a flight from Knoxville to Panama City, Florida?

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Alternative routes for Knoxville to Panama City

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Top 2 airlines flying from Knoxville to Panama City

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Cheapest flights from Knoxville to Panama City
Explore the most affordable flight options available from Knoxville to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.