HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$271+ Cheap flights from Charleston to Panama City, FL (CHS - ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Panama City

Cheapest flights from Charleston to Panama City
Explore the most affordable flight options available from Charleston to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:44 amCHS - ECP
1 stop4h 53mAmerican Airlines
lun. 12/294:09 pmECP - CHS
1 stop5h 02mAmerican Airlines
Deal found 12/11$405
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:35 amCHS - ECP
1 stop4h 42mDelta
lun. 12/298:02 amECP - CHS
1 stop6h 06mDelta
Deal found 12/9$438
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/215:25 amCHS - ECP
1 stop4h 12mDelta
jue. 12/258:02 amECP - CHS
1 stop6h 08mDelta
Deal found 12/9$457
This Southwest deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/216:10 amCHS - ECP
2 stops7h 00mSouthwest
jue. 12/254:25 pmECP - CHS
1 stop3h 50mSouthwest
Deal found 12/9$550
This Southwest deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/2011:35 amCHS - ECP
1 stop4h 20mSouthwest
mié. 12/2410:00 amECP - CHS
2 stops7h 40mSouthwest
Deal found 12/8$603

Find flight deals from Charleston to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$271
(Delta)

Popular in

May

Cheapest in

March

Average price

$481
Provider with most accurate pricing for Charleston-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Panama City NW Florida Beaches flights.
Search Deals
From Charleston to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Charleston to Panama City that are best for you.

Fly from

Charleston

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

jue. 1/15

5:25 am-9:12 am

1 stop4h 47m

Panama City NW Florida Beaches

dom. 1/18

6:00 am-11:48 am

1 stop4h 48m

$271

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

mié. 2/4

6:30 am-8:39 am

1 stop3h 09m

Panama City NW Florida Beaches

lun. 2/9

3:45 pm-8:57 pm

1 stop4h 12m

$295

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

mié. 1/14

6:00 am-5:33 pm

2 stops12h 33m

Panama City NW Florida Beaches

dom. 1/18

6:03 pm-11:07 pm

1 stop4h 04m

$299

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

mar. 1/20

9:05 am-6:10 pm

2 stops10h 05m

Panama City NW Florida Beaches

mié. 1/21

8:00 am-12:50 pm

1 stop3h 50m

$322

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

vie. 1/2

5:30 am-10:17 am

1 stop5h 47m

Panama City NW Florida Beaches

mié. 1/7

5:14 pm-11:55 pm

1 stop5h 41m

$335

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

mié. 2/4

9:27 am-5:33 pm

2 stops9h 06m

Panama City NW Florida Beaches

lun. 2/9

12:03 pm-4:56 pm

1 stop3h 53m

$336

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

lun. 1/5

5:30 pm-10:51 pm

1 stop6h 21m

Panama City NW Florida Beaches

lun. 1/12

7:20 am-11:48 am

1 stop3h 28m

$347

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

mié. 1/14

9:05 am-6:10 pm

2 stops10h 05m

Panama City NW Florida Beaches

dom. 1/18

8:00 am-3:50 pm

2 stops6h 50m

$352

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

jue. 1/8

6:55 am-2:55 pm

2 stops9h 00m

Panama City NW Florida Beaches

lun. 1/12

10:30 am-5:35 pm

1 stop6h 05m

$360

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

dom. 12/21

9:22 am-1:19 pm

1 stop4h 57m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 11 results
1
2

Compare providers for flights from Charleston to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Panama City in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Charleston-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Charleston-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama City

What is the cheapest month to book a flight from Charleston to Panama City, Florida?

Currently, September is the cheapest month in which you can book a flight from Charleston to Panama City, Florida (average of $138). Flying from Charleston to Panama City, Florida in May is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to ECP?

Find hourly flight availability from Charleston to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

One of the essential ways to save on airfare from Charleston to Panama City, Florida is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 28% on airfare.

How much does it cost to fly round-trip from Charleston to Panama City, Florida?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated diciembre 12, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,253 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,008 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,050 reviews
Southwest
7.9
Good
4,253 reviews

Entertainment

7.5

Overall

7.9

Comfort

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Charleston to Panama City, Florida?

    For as low as $271, Delta can have you in Panama City, Florida from Charleston in 4h 47m. Airlines will cover a distance of 381 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Charleston to Panama City, Florida round-trip?

    According to our current data, American Airlines ($216), Delta ($231), and Southwest ($283) offers the cheapest pricing from Charleston to Panama City, Florida. You may be able to fly from Charleston to Panama City, Florida for 41% less than the average price by searching for these airlines.

  • Can I find deals for flights from Charleston to Panama City that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama City.

  • Can I find deals for business class flights from Charleston to Panama City?

    Yes. Cheapflights offers flight deals from Charleston to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama City, Florida?

    Currently, September is the cheapest month in which you can book a flight from Charleston to Panama City, Florida (average of $138). Flying from Charleston to Panama City, Florida in May is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Miami flights
Charlotte to Orlando flights
Charlotte to Fort Lauderdale flights
Charlotte to Tampa flights
Charleston to Miami flights
Charlotte to Fort Myers flights
Charleston to Fort Lauderdale flights
Greenville to Miami flights
Charlotte to Sarasota flights
Charlotte to West Palm Beach flights
Columbia to Orlando flights
Charlotte to Key West flights
Charleston to Tampa flights
Charlotte to Jacksonville flights
Myrtle Beach to Fort Lauderdale flights
Columbia to Miami flights
Savannah to Miami flights
Myrtle Beach to Miami flights
Charleston to Orlando flights
Myrtle Beach to Orlando flights
Charlotte to Pensacola flights
Greenville to Orlando flights
Charlotte to Panama City flights
Charleston to Key West flights
Columbia to Tampa flights
Savannah to Fort Lauderdale flights
Charleston to Fort Myers flights
Greenville to Fort Lauderdale flights
Savannah to Orlando flights
Columbia to West Palm Beach flights
Myrtle Beach to Fort Myers flights
Myrtle Beach to Key West flights
Charlotte to Melbourne flights
Savannah to Fort Myers flights
Greenville to Sarasota flights
Greenville to Tampa flights
Charleston to Sarasota flights
Charlotte to Valparaiso flights
Charlotte to Tallahassee flights
Columbia to Fort Lauderdale flights
Savannah to Pensacola flights
Myrtle Beach to West Palm Beach flights
Augusta to Fort Lauderdale flights
Greenville to Key West flights
Augusta to Miami flights
Charleston to West Palm Beach flights
Savannah to Tampa flights
Greenville to West Palm Beach flights
Myrtle Beach to Tampa flights
Charlotte to St Petersburg flights

Top 3 airlines flying from Charleston to Panama City

Discover the top 3 airlines that operate flights from Charleston to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$216Average$361FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$369FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$283Average$447FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.