HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
North Carolina

$81+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — CLT
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to North Carolina with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$243
(Frontier)

One-way from

$81
(Frontier)

Popular in

March

Cheapest in

September

Average price

$377

Good round-trip deal

$376 or less

Good one-way deal

$199 or less
Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.
Search Deals
From Des Moines to North Carolina
Search Deals
One-way flight from Des Moines to North Carolina
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2025
Search Deals
Price to beat on a round-trip flight from Des Moines to North Carolina.
Search Deals
Price to beat on a one-way flight from Des Moines to North Carolina.
Search Deals

Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/148:00 amDSM - TYS
1 stop11h 39mAllegiant Air
Fri 4/1811:13 amTYS - DSM
1 stop12h 08mAllegiant Air
Deal found 2/20$237
This Frontier deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/287:17 pmDSM - CLT
1 stop10h 51mFrontier
Mon 3/38:08 amCLT - DSM
1 stop11h 06mFrontier
Deal found 2/20$243
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/81:32 pmDSM - AVL
1 stop20h 21mAllegiant Air
Wed 3/122:45 pmAVL - DSM
1 stop7h 53mAllegiant Air
Deal found 2/21$245
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/55:22 pmDSM - TYS
1 stop5h 20mDelta
Wed 4/95:45 amTYS - DSM
1 stop5h 52mDelta
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/113:23 pmDSM - CLT
1 stop4h 12mAmerican Airlines
Fri 3/148:30 pmCLT - DSM
Nonstop2h 34mAmerican Airlines
Deal found 2/21$253
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/512:49 pmDSM - TYS
2 stops7h 34mAmerican Airlines
Wed 4/912:14 pmTYS - DSM
1 stop5h 29mAmerican Airlines
Deal found 2/19$254
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/271:00 pmDSM - AVL
1 stop4h 54mAmerican Airlines
Sun 3/306:04 pmAVL - DSM
1 stop5h 03mAmerican Airlines
Deal found 2/20$254
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:30 pmDSM - ILM
1 stop4h 32mDelta
Fri 9/1212:15 pmILM - DSM
1 stop8h 38mDelta
Deal found 2/21$259
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/175:59 pmDSM - CLT
1 stop4h 35mDelta
Mon 3/245:21 pmCLT - DSM
1 stop4h 59mDelta
Deal found 2/21$263
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/211:12 pmDSM - ILM
2 stops8h 28mAmerican Airlines
Sun 5/258:15 pmILM - DSM
1 stop4h 43mAmerican Airlines
Deal found 2/22$264
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/141:31 pmDSM - TYS
2 stops28h 01mMultiple Airlines
Fri 4/1811:13 amTYS - DSM
1 stop12h 08mMultiple Airlines
Deal found 2/20$265
This Mytrip deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/77:30 amDSM - CLT
1 stop16h 02mMultiple Airlines
Mon 4/147:00 amCLT - DSM
1 stop8h 00mMultiple Airlines
Deal found 2/21$266

Find flights from Des Moines to North Carolina within your budget

Customize your flight search to find flights from Des Moines to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Des Moines

Fly to

North Carolina

Route

Depart

Return

Price

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 4/14

8:00 am-8:39 pm

1 stop11h 39m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-10:21 pm

1 stop12h 08m

$237

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 3/22

2:07 pm-5:30 pm

Nonstop2h 23m

Charlotte Douglas

Sat 3/29

9:25 pm-10:56 pm

Nonstop2h 31m

$243

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Sat 3/8

1:32 pm-10:53 am

1 stop20h 21m

Asheville Regional

Wed 3/12

2:45 pm-9:38 pm

1 stop7h 53m

$245

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 4/5

5:22 pm-11:42 pm

1 stop5h 20m

Knoxville McGhee Tyson

Wed 4/9

5:45 am-10:37 am

1 stop5h 52m

$249

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Sat 4/5

12:49 pm-9:23 pm

2 stops7h 34m

Knoxville McGhee Tyson

Wed 4/9

12:14 pm-4:43 pm

1 stop5h 29m

$254

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Thu 3/27

1:00 pm-6:54 pm

1 stop4h 54m

Asheville Regional

Sun 3/30

6:04 pm-10:07 pm

1 stop5h 03m

$254

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 3/17

5:59 pm-11:34 pm

1 stop4h 35m

Charlotte Douglas

Mon 3/24

5:21 pm-9:20 pm

1 stop4h 59m

$263

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Wed 5/21

1:12 pm-10:40 pm

2 stops8h 28m

Wilmington New Hanover County

Sun 5/25

8:15 pm-11:58 pm

1 stop4h 43m

$264

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Mon 4/14

1:31 pm-6:32 pm

2 stops28h 01m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-10:21 pm

1 stop12h 08m

$265

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Mon 4/7

7:30 am-12:32 am

1 stop16h 02m

Charlotte Douglas

Mon 4/14

7:00 am-2:00 pm

1 stop8h 00m

$266

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 49 results
1
2
3
...
5

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to North Carolina

Get recent, data-driven insights about flights from Des Moines to North Carolina including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $248). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Weekly flight availability from Des Moines to North Carolina

Explore weekly flight availability from Des Moines to North Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 22, 2025.

The most flights from DSM to USNC are scheduled on a Monday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (2 on average).

Rainfall in North Carolina by month

Plan your trip to North Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in North Carolina ranges from 3.0 - 4.2 inches per month. August is typically the wettest month, when rainfall can reach 4.2 in. April is typically the driest time to visit North Carolina when rainfall is around 3.0 in.

Temperature in North Carolina by month

Plan your trip to North Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing North Carolina

Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated February 22, 2025.
To help decide which airline to fly from Des Moines to North Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,396 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Entertainment

7.6

Crew

8.7

Comfort

8.1

Overall

8.1

Food

7.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to North Carolina?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $81. However, be on the lookout for offers from Allegiant Air and American Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.

  • What are the most popular routes from Des Moines to North Carolina?

    Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Raleigh-Durham or Des Moines - Myrtle Beach Intl when deciding on the best route from Des Moines to North Carolina.

  • What are the cheapest flights from Des Moines to North Carolina?

    On average you can expect to pay $779 for a flight from Des Moines to North Carolina. The cheapest flight overall is $159 while the most popular route, (Des Moines - Charlotte Douglas) is currently priced at $212.

  • Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

    Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to North Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

  • Can I find deals for business class flights from Des Moines to North Carolina?

    Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to North Carolina?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $248). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to Denver flights
Cedar Rapids to Denver flights
Omaha to Dallas/Fort Worth flights
Omaha to Las Vegas flights
Omaha to Seattle flights
Cedar Rapids to Sky Harbor Intl flights
Des Moines to Sky Harbor Intl flights
Omaha to Orlando flights
Omaha to Denver flights
Des Moines to Dallas/Fort Worth flights
Omaha to Sky Harbor Intl flights
Cedar Rapids to Dallas/Fort Worth flights
Omaha to O'Hare Intl flights
Des Moines to Las Vegas flights
Cedar Rapids to Orlando flights
Des Moines to O'Hare Intl flights
Omaha to Miami flights
Des Moines to John F Kennedy Intl flights
Des Moines to Seattle flights
Omaha to San Francisco flights
Des Moines to LaGuardia flights
Des Moines to Orlando flights
Des Moines to Miami flights
Omaha to Salt Lake City flights
Cedar Rapids to Seattle flights
Moline to Denver flights
Des Moines to Atlanta flights
Omaha to John F Kennedy Intl flights
Moline to Sky Harbor Intl flights
Omaha to Hobby flights
Omaha to LaGuardia flights
Omaha to Los Angeles flights
Cedar Rapids to Atlanta flights
Omaha to Atlanta flights
Cedar Rapids to John F Kennedy Intl flights
Omaha to San Diego flights
Omaha to Nashville flights
Cedar Rapids to Reagan-National flights
Des Moines to Reagan-National flights
Omaha to Philadelphia flights
Omaha to Reagan-National flights
Omaha to Newark flights
Cedar Rapids to Las Vegas flights
Cedar Rapids to Tampa flights
Moline to Orlando flights
Cedar Rapids to LaGuardia flights
Omaha to Tampa flights
Cedar Rapids to Miami flights
Cedar Rapids to Newark flights
Omaha to Love Field flights

Top 5 airlines flying from Des Moines to North Carolina

Discover the top 5 airlines that operate flights from Des Moines to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$359FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$146Average$196FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$196Average$393FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$218Average$429FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$361Average$436FlexibilityNo cancel feeOn-time63%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.