What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $106. However, be on the lookout for offers from Allegiant Air and United Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.

What are the most popular routes from Des Moines to North Carolina?

Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Myrtle Beach Intl or Des Moines - Norfolk when deciding on the best route from Des Moines to North Carolina.

What are the most popular airlines that fly from Des Moines to North Carolina?

Consider American Airlines, Delta or United Airlines when booking your flight. These represent the most popular airlines when flying from Des Moines to North Carolina.

How far in advance should I book a flight from Des Moines to North Carolina?

Find a great deal and save up to 93% by booking at least 25 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Des Moines to North Carolina within the next two weeks, with the cheapest ticket starting at $342.

What is the cheapest month to fly from Des Moines to North Carolina?

Flights from Des Moines to North Carolina lean towards being more expensive in March. Prices are generally better when you fly from Des Moines to North Carolina in September, with the cheapest ticket starting at $305.

What airport do you fly from for flights from Des Moines to North Carolina?

Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to North Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

Can I find deals for business class flights from Des Moines to North Carolina?

Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$94+ Flights from Des Moines to North Carolina

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Cheap flight deals from Des Moines to North Carolina

Most accurate provider	FlightHub 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$229 (Mytrip)
One-way from	$94 (Mytrip)
Popular in	March
Cheapest in	September
Average price	$386
Good round-trip deal	$363 or less
Good one-way deal	$154 or less

Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.

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From Des Moines to North Carolina

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One-way flight from Des Moines to North Carolina

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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Des Moines to North Carolina.

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Price to beat on a one-way flight from Des Moines to North Carolina.

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Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Thu 5/298:30 amDSM - ORF

1 stop8h 37mAllegiant Air

Thu 6/53:50 pmORF - DSM

1 stop17h 35mAllegiant Air

Deal found 4/14

$226

Fri 5/96:00 amDSM - AVL

1 stop16h 39mAllegiant Air

Sat 5/109:56 pmAVL - DSM

1 stop18h 02mAllegiant Air

Deal found 4/15

$229

Wed 4/307:27 pmDSM - CLT

1 stop19h 38mFrontier

Sun 5/45:06 pmCLT - DSM

1 stop26h 24mFrontier

Deal found 4/15

$231

Thu 5/296:35 pmDSM - AVL

1 stop4h 09mDelta

Fri 5/3012:40 pmAVL - DSM

1 stop7h 26mDelta

Deal found 4/14

$237

Thu 5/296:35 pmDSM - TYS

1 stop4h 16mDelta

Thu 6/56:50 amTYS - DSM

1 stop4h 29mDelta

Deal found 4/14

$243

Thu 9/46:20 amDSM - GSO

1 stop4h 21mDelta

Sun 9/75:25 amGSO - DSM

1 stop5h 49mDelta

Deal found 4/14

$249

Fri 5/308:35 amDSM - CLT

1 stop7h 12mMultiple Airlines

Fri 6/64:32 pmCLT - DSM

1 stop25h 46mMultiple Airlines

Deal found 4/15

$253

Fri 5/168:30 amDSM - ORF

1 stop28h 46mMultiple Airlines

Mon 5/1912:13 pmORF - DSM

1 stop10h 11mMultiple Airlines

Deal found 4/14

$257

Thu 5/297:15 pmDSM - MYR

1 stop23h 38mMultiple Airlines

Thu 6/57:06 pmMYR - DSM

1 stop20h 39mMultiple Airlines

Deal found 4/14

$257

Tue 4/2911:38 amDSM - TYS

1 stop4h 06mUnited Airlines

Sat 5/34:14 pmTYS - DSM

1 stop8h 25mUnited Airlines

Deal found 4/14

$259

Tue 4/293:34 pmDSM - GSO

1 stop5h 02mUnited Airlines

Sat 5/35:34 pmGSO - DSM

1 stop5h 18mUnited Airlines

Deal found 4/14

$259

Sat 7/265:26 pmDSM - ILM

1 stop5h 33mAmerican Airlines

Wed 7/307:47 pmILM - DSM

1 stop4h 14mAmerican Airlines

Deal found 4/13

$259

Best flights from Des Moines to North Carolina
Discover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 15, 2025.

Fri 5/96:00 amDSM - AVL

1 stop16h 39mAllegiant Air

Sat 5/109:56 pmAVL - DSM

1 stop18h 02mAllegiant Air

Deal found 4/15

$229

Wed 4/307:27 pmDSM - CLT

1 stop19h 38mFrontier

Sun 5/45:06 pmCLT - DSM

1 stop26h 24mFrontier

Deal found 4/15

$231

Thu 5/296:35 pmDSM - AVL

1 stop4h 09mDelta

Fri 5/3012:40 pmAVL - DSM

1 stop7h 26mDelta

Deal found 4/14

$237

Wed 5/1412:48 pmDSM - TYS

1 stop8h 07mAmerican Airlines

Sat 5/177:00 amTYS - DSM

1 stop6h 05mAmerican Airlines

Deal found 4/15

$249

Fri 5/306:00 amDSM - MYR

1 stop9h 37mMultiple Airlines

Fri 6/66:12 pmMYR - DSM

1 stop24h 06mMultiple Airlines

Deal found 4/15

$249

Tue 4/2911:38 amDSM - TYS

1 stop4h 06mUnited Airlines

Sat 5/34:14 pmTYS - DSM

1 stop8h 25mUnited Airlines

Deal found 4/14

$259

Tue 5/135:40 amDSM - RDU

2 stops7h 20mSouthwest

Tue 5/206:50 pmRDU - DSM

1 stop4h 15mSouthwest

Deal found 4/14

$276

Thu 5/296:35 pmDSM - TYS

1 stop4h 16mDelta

Thu 6/56:50 amTYS - DSM

1 stop4h 29mDelta

Deal found 4/14

$243

Fri 5/308:35 amDSM - CLT

1 stop7h 12mMultiple Airlines

Fri 6/64:32 pmCLT - DSM

1 stop25h 46mMultiple Airlines

Deal found 4/15

$253

Tue 4/293:34 pmDSM - GSO

1 stop5h 02mUnited Airlines

Sat 5/35:34 pmGSO - DSM

1 stop5h 18mUnited Airlines

Deal found 4/14

$259

Sat 7/126:00 amDSM - TYS

1 stop14h 40mAllegiant Air

Sat 7/197:30 amTYS - DSM

1 stop17h 07mAllegiant Air

Deal found 4/14

$265

Thu 9/46:20 amDSM - GSO

1 stop4h 21mDelta

Sun 9/75:25 amGSO - DSM

1 stop5h 49mDelta

Deal found 4/14

$249

Last-minute flights from Des Moines to North Carolina
Discover last-minute flight deals from Des Moines to North Carolina. Data last updated April 15, 2025 and is based on user searches.

Mon 4/213:53 pmDSM - TYS

1 stop22h 29mAllegiant Air

Wed 4/2312:59 pmTYS - DSM

1 stop22h 23mAllegiant Air

Deal found 4/14

$313

Mon 4/216:30 amDSM - CLT

2 stops26h 55mMultiple Airlines

Fri 4/2510:30 amCLT - DSM

1 stop13h 25mMultiple Airlines

Deal found 4/14

$366

Mon 4/211:59 pmDSM - CLT

Nonstop2h 25mAmerican Airlines

Sat 4/2611:59 amCLT - DSM

Nonstop2h 14mAmerican Airlines

Deal found 4/14

$535

Mon 4/213:34 pmDSM - CLT

1 stop4h 52mUnited Airlines

Sat 4/266:36 amCLT - DSM

1 stop4h 44mUnited Airlines

Deal found 4/14

$555

Mon 4/211:59 pmDSM - TYS

1 stop4h 07mAmerican Airlines

Wed 4/236:05 pmTYS - DSM

2 stops6h 39mAmerican Airlines

Deal found 4/14

$615

Tue 4/227:25 amDSM - ORF

1 stop8h 08mAmerican Airlines

Mon 4/285:54 amORF - DSM

1 stop14h 07mAmerican Airlines

Deal found 4/15

$585

Tue 4/225:40 amDSM - ORF

2 stops10h 25mSouthwest

Mon 4/283:15 pmORF - DSM

1 stop7h 55mSouthwest

Deal found 4/15

$592

Wed 4/235:40 amDSM - CLT

1 stop6h 40mSouthwest

Wed 4/233:40 pmCLT - DSM

1 stop7h 25mSouthwest

Deal found 4/14

$390

Fri 4/257:27 pmDSM - RDU

1 stop20h 22mFrontier

Sun 4/275:49 pmRDU - DSM

1 stop25h 48mFrontier

Deal found 4/15

$330

Fri 4/251:31 pmDSM - RDU

2 stops20h 13mMultiple Airlines

Sun 4/275:35 pmRDU - DSM

2 stops30h 38mMultiple Airlines

Deal found 4/15

$517

Fri 4/255:29 pmDSM - RDU

1 stop6h 03mAmerican Airlines

Mon 4/286:00 amRDU - DSM

1 stop6h 21mAmerican Airlines

Deal found 4/14

$572

Fri 4/253:34 pmDSM - RDU

1 stop4h 58mUnited Airlines

Mon 4/281:20 pmRDU - DSM

2 stops9h 32mUnited Airlines

Deal found 4/14

$577

One-way flights from Des Moines to North Carolina
Search for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated April 15, 2025.

Mon 6/168:35 amDSM - RDU

1 stop8h 06mMultiple Airlines

Deal found 4/15

$94

Fri 4/257:27 pmDSM - RDU

1 stop20h 22mFrontier

Deal found 4/14

$106

Wed 5/217:30 pmDSM - CLT

1 stop20h 02mFrontier

Deal found 4/14

$116

Sun 6/17:15 pmDSM - MYR

1 stop23h 38mMultiple Airlines

Deal found 4/15

$123

Sun 6/18:30 amDSM - MYR

2 stops28h 25mAllegiant Air

Deal found 4/15

$134

Tue 5/131:40 pmDSM - ORF

1 stop8h 50mUnited Airlines

Deal found 4/14

$136

Tue 5/136:45 amDSM - RDU

1 stop7h 20mAmerican Airlines

Deal found 4/15

$136

Tue 5/1311:26 amDSM - RDU

2 stops11h 20mUnited Airlines

Deal found 4/15

$141

Wed 6/187:11 amDSM - RDU

1 stop6h 43mDelta

Deal found 4/15

$149

Fri 5/3012:48 pmDSM - MYR

1 stop5h 14mAmerican Airlines

Deal found 4/15

$149

Sun 5/1111:26 amDSM - CLT

1 stop5h 55mDelta

Deal found 4/14

$154

Fri 4/253:53 pmDSM - AVL

1 stop22h 15mAllegiant Air

Deal found 4/14

$156

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Fri 5/9

6:00 am-11:39 pm

1 stop16h 39m

Asheville Regional

Sat 5/10

9:56 pm-2:58 pm

1 stop18h 02m

$229

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Wed 4/30

7:27 pm-4:05 pm

1 stop19h 38m

Charlotte Douglas

Sun 5/4

5:06 pm-6:30 pm

1 stop26h 24m

$231

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Thu 5/29

6:35 pm-11:44 pm

1 stop4h 09m

Asheville Regional

Fri 5/30

12:40 pm-7:06 pm

1 stop7h 26m

$237

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 5/29

6:35 pm-11:51 pm

1 stop4h 16m

Knoxville McGhee Tyson

Thu 6/5

6:50 am-10:19 am

1 stop4h 29m

$243

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Wed 5/14

12:48 pm-9:55 pm

1 stop8h 07m

Knoxville McGhee Tyson

Sat 5/17

7:00 am-12:05 pm

1 stop6h 05m

$249

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Thu 9/4

6:20 am-11:41 am

1 stop4h 21m

Greensboro/H. Point

Sun 9/7

5:25 am-10:14 am

1 stop5h 49m

$249

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/30

8:35 am-4:47 pm

1 stop7h 12m

Charlotte Douglas

Fri 6/6

4:32 pm-5:18 pm

1 stop25h 46m

$253

Des MoinesMyrtle Beach

DSM - MYR

DSMMYR

Des Moines

Thu 5/29

7:15 pm-7:53 pm

1 stop23h 38m

Myrtle Beach Intl

Thu 6/5

7:06 pm-2:45 pm

1 stop20h 39m

$257

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Tue 4/29

11:38 am-4:44 pm

1 stop4h 06m

Knoxville McGhee Tyson

Sat 5/3

4:14 pm-11:39 pm

1 stop8h 25m

$259

Des MoinesGreensboro

DSM - GSO

DSMGSO

Des Moines

Tue 4/29

3:34 pm-9:36 pm

1 stop5h 02m

Greensboro/H. Point

Sat 5/3

5:34 pm-9:52 pm

1 stop5h 18m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 54 results

...

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Rainfall in North Carolina by month

In terms of precipitation, rainfall in North Carolina ranges from 3.0 - 4.2 inches per month. August is typically the wettest month, when rainfall can reach 4.2 in. April is typically the driest time to visit North Carolina when rainfall is around 3.0 in.

Temperature in North Carolina by month

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing North Carolina

To help decide which airline to fly from Des Moines to North Carolina, see what other customers have to say about Alaska Airlines, Southwest and Delta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Alaska Airlines

8.0

Very good

9,871 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Southwest

8.0

Very good

4,279 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Delta

8.0

Very good

7,918 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

United Airlines

7.4

Good

8,658 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Allegiant Air

7.3

Good

734 reviews

Alaska Airlines

8.0

Very good

9,871 reviews

Reviews

1 / 20

4.0

Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

What airport do you fly from for flights from Des Moines to North Carolina?
Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.
What are the cheapest airlines to fly from Des Moines to North Carolina one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $106. However, be on the lookout for offers from Allegiant Air and United Airlines, as they are both options that can get you from Des Moines to North Carolina for a low price.
What are the most popular routes from Des Moines to North Carolina?
Most travelers choose Des Moines - Charlotte Douglas, Des Moines - Myrtle Beach Intl or Des Moines - Norfolk when deciding on the best route from Des Moines to North Carolina.
Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?
Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to North Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.
Can I find deals for business class flights from Des Moines to North Carolina?
Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to North Carolina?
Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $206). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Des Moines to North Carolina

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$131	Average$344	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$208	Average$360	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$229	Average$426	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$312	Average$431	FlexibilityNo cancel fee	On-time63%

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$94+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to North Carolina with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated April 15, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North CarolinaExplore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

Rainfall in North Carolina by month

Plan your trip to North Carolina by taking into account the average rainfall totals by month.

Temperature in North Carolina by month

Plan your trip to North Carolina by taking into account the average temperature totals by month.

Reviews of airlines servicing North Carolina

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to North Carolina?

What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

What are the most popular routes from Des Moines to North Carolina?

Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

How can I find direct flights from Des Moines to North Carolina?

Can I find deals for business class flights from Des Moines to North Carolina?

What is the cheapest month to book a flight from Des Moines to North Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Des Moines to North Carolina

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Travel Smart

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.