What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $97. However, be on the lookout for offers from American Airlines and Frontier, as they are both options that can get you from Des Moines to North Carolina for a low price.

What are the most popular routes from Des Moines to North Carolina?

Most travelers choose Des Moines - Myrtle Beach Intl, Des Moines - Charlotte Douglas or Des Moines - Raleigh-Durham when deciding on the best route from Des Moines to North Carolina.

What are the cheapest flights from Des Moines to North Carolina?

On average you can expect to pay $807 for a flight from Des Moines to North Carolina. The cheapest flight overall is $135 while the most popular route, (Des Moines - Myrtle Beach Intl) is currently priced at $260.

What are the most popular airlines that fly from Des Moines to North Carolina?

Consider American Airlines, Delta or Frontier when booking your flight. These represent the most popular airlines when flying from Des Moines to North Carolina.

How far in advance should I book a flight from Des Moines to North Carolina?

Find a great deal and save up to 44% by booking at least 39 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Des Moines to North Carolina within the next two weeks, with the cheapest ticket starting at $342.

What is the cheapest month to fly from Des Moines to North Carolina?

Flights from Des Moines to North Carolina lean towards being more expensive in March. Prices are generally better when you fly from Des Moines to North Carolina in April, with the cheapest ticket starting at $193.

What airport do you fly from for flights from Des Moines to North Carolina?

Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to North Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.

Can I find deals for business class flights from Des Moines to North Carolina?

Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$97+ Flights from Des Moines to North Carolina

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Cheap flight deals from Des Moines to North Carolina

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$224 (American Airlines)
One-way from	$97 (Mytrip)
Popular in	March
Cheapest in	April
Average price	$441
Good round-trip deal	$357 or less
Good one-way deal	$149 or less

Provider with most accurate pricing for Des Moines-Charlotte Douglas flight deals.

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Provider most trusted by Cheapflights users for Des Moines-Charlotte Douglas flights.

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From Des Moines to North Carolina

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One-way flight from Des Moines to North Carolina

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High demand for flights, 2% potential price rise

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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).

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Average for round-trip flights in March 2025

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Price to beat on a round-trip flight from Des Moines to North Carolina.

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Price to beat on a one-way flight from Des Moines to North Carolina.

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Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

Fri 7/46:00 amDSM - AVL

1 stop4h 24mAmerican Airlines

Thu 7/102:23 pmAVL - DSM

1 stop6h 00mAmerican Airlines

Deal found 3/25

$224

Mon 4/73:50 pmDSM - AVL

1 stop17h 58mAllegiant Air

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mAllegiant Air

Deal found 3/24

$234

Thu 5/83:59 pmDSM - TYS

1 stop21h 28mAllegiant Air

Thu 5/1512:01 pmTYS - DSM

1 stop26h 57mAllegiant Air

Deal found 3/24

$240

Fri 4/118:17 pmDSM - CLT

1 stop21h 40mFrontier

Thu 4/1710:20 pmCLT - DSM

1 stop21h 57mFrontier

Deal found 3/24

$240

Thu 9/47:25 amDSM - GSO

1 stop5h 37mDelta

Sun 9/75:25 amGSO - DSM

1 stop5h 49mDelta

Deal found 3/25

$249

Mon 4/286:25 pmDSM - AVL

1 stop4h 25mDelta

Sat 5/36:05 amAVL - DSM

1 stop5h 36mDelta

Deal found 3/24

$249

Mon 4/71:31 pmDSM - AVL

2 stops31h 14mMultiple Airlines

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mMultiple Airlines

Deal found 3/24

$250

Sat 5/246:30 amDSM - CLT

1 stop4h 41mDelta

Sat 5/316:35 pmCLT - DSM

1 stop4h 55mDelta

Deal found 3/24

$253

Fri 5/92:28 pmDSM - CLT

2 stops24h 23mMultiple Airlines

Fri 5/164:32 pmCLT - DSM

1 stop5h 23mMultiple Airlines

Deal found 3/25

$254

Tue 4/157:20 amDSM - ILM

1 stop7h 56mDelta

Wed 4/234:00 pmILM - DSM

1 stop7h 38mDelta

Deal found 3/25

$259

Tue 4/156:45 amDSM - ILM

2 stops7h 52mAmerican Airlines

Wed 4/235:00 amILM - DSM

2 stops9h 41mAmerican Airlines

Deal found 3/25

$269

Wed 9/105:25 amDSM - TYS

1 stop6h 49mAmerican Airlines

Sun 9/147:44 amTYS - DSM

1 stop5h 41mAmerican Airlines

Deal found 3/25

$279

Best flights from Des Moines to North Carolina
Discover carefully curated flight deals from Des Moines to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2025.

Fri 7/46:00 amDSM - AVL

1 stop4h 24mAmerican Airlines

Thu 7/102:23 pmAVL - DSM

1 stop6h 00mAmerican Airlines

Deal found 3/25

$224

Mon 4/73:50 pmDSM - AVL

1 stop17h 58mAllegiant Air

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mAllegiant Air

Deal found 3/24

$234

Fri 4/118:17 pmDSM - CLT

1 stop21h 40mFrontier

Thu 4/1710:20 pmCLT - DSM

1 stop21h 57mFrontier

Deal found 3/24

$240

Mon 4/286:25 pmDSM - AVL

1 stop4h 25mDelta

Sat 5/36:05 amAVL - DSM

1 stop5h 36mDelta

Deal found 3/24

$249

Mon 4/71:31 pmDSM - AVL

2 stops31h 14mMultiple Airlines

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mMultiple Airlines

Deal found 3/24

$250

Mon 5/125:30 pmDSM - RDU

1 stop3h 55mSouthwest

Wed 5/146:50 pmRDU - DSM

1 stop4h 15mSouthwest

Deal found 3/25

$297

Fri 5/23:34 pmDSM - RDU

2 stops7h 12mUnited Airlines

Mon 5/56:00 amRDU - DSM

2 stops9h 38mUnited Airlines

Deal found 3/25

$327

Thu 5/83:59 pmDSM - TYS

1 stop21h 28mAllegiant Air

Thu 5/1512:01 pmTYS - DSM

1 stop26h 57mAllegiant Air

Deal found 3/24

$240

Sat 5/246:30 amDSM - CLT

1 stop4h 41mDelta

Sat 5/316:35 pmCLT - DSM

1 stop4h 55mDelta

Deal found 3/24

$253

Fri 5/92:28 pmDSM - CLT

2 stops24h 23mMultiple Airlines

Fri 5/164:32 pmCLT - DSM

1 stop5h 23mMultiple Airlines

Deal found 3/25

$254

Tue 4/156:45 amDSM - ILM

2 stops7h 52mAmerican Airlines

Wed 4/235:00 amILM - DSM

2 stops9h 41mAmerican Airlines

Deal found 3/25

$269

Tue 4/157:20 amDSM - ILM

1 stop7h 56mDelta

Wed 4/234:00 pmILM - DSM

1 stop7h 38mDelta

Deal found 3/25

$259

Last-minute flights from Des Moines to North Carolina
Discover last-minute flight deals from Des Moines to North Carolina. Data last updated March 26, 2025 and is based on user searches.

Mon 3/316:00 amDSM - ORF

1 stop7h 23mMultiple Airlines

Wed 4/210:45 amORF - DSM

3 stops29h 21mMultiple Airlines

Deal found 3/25

$479

Mon 3/3111:38 amDSM - ORF

3 stops10h 52mUnited Airlines

Tue 4/11:29 pmORF - DSM

2 stops9h 23mUnited Airlines

Deal found 3/25

$911

Tue 4/17:25 amDSM - ORF

1 stop7h 35mSouthwest

Mon 4/72:45 pmORF - DSM

1 stop9h 15mSouthwest

Deal found 3/25

$557

Thu 4/31:27 pmDSM - CLT

2 stops26h 03mMultiple Airlines

Sun 4/66:07 pmCLT - DSM

1 stop19h 34mMultiple Airlines

Deal found 3/25

$438

Thu 4/35:06 amDSM - CLT

1 stop5h 33mAmerican Airlines

Sun 4/68:39 pmCLT - DSM

Nonstop2h 28mAmerican Airlines

Deal found 3/25

$485

Thu 4/310:22 amDSM - CLT

1 stop7h 02mDelta

Sun 4/66:04 amCLT - DSM

1 stop4h 33mDelta

Deal found 3/25

$495

Thu 4/36:45 pmDSM - RDU

1 stop3h 45mSouthwest

Sat 4/511:40 amRDU - DSM

1 stop5h 00mSouthwest

Deal found 3/25

$557

Thu 4/33:40 pmDSM - CLT

2 stops7h 19mUnited Airlines

Sun 4/65:32 pmCLT - DSM

1 stop5h 20mUnited Airlines

Deal found 3/25

$570

Fri 4/48:17 pmDSM - RDU

1 stop19h 07mFrontier

Sun 4/67:42 pmRDU - DSM

1 stop24h 37mFrontier

Deal found 3/25

$298

Fri 4/47:30 amDSM - RDU

1 stop25h 33mMultiple Airlines

Sun 4/66:55 pmRDU - DSM

3 stops29h 13mMultiple Airlines

Deal found 3/25

$394

Mon 4/73:50 pmDSM - AVL

1 stop17h 58mAllegiant Air

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mAllegiant Air

Deal found 3/24

$234

Mon 4/71:31 pmDSM - AVL

2 stops31h 14mMultiple Airlines

Thu 4/245:47 pmAVL - DSM

1 stop6h 09mMultiple Airlines

Deal found 3/24

$250

One-way flights from Des Moines to North Carolina
Search for one-way flight options from Des Moines to North Carolina. Find affordable one-way fares based on user searches. Data last updated March 26, 2025.

Sun 4/63:56 pmDSM - TYS

1 stop21h 35mAllegiant Air

Deal found 3/25

$97

Thu 4/108:30 amDSM - AVL

1 stop12h 33mAllegiant Air

Deal found 3/25

$105

Sun 5/252:01 pmDSM - CLT

Nonstop2h 22mAmerican Airlines

Deal found 3/25

$122

Fri 4/188:17 pmDSM - CLT

1 stop21h 40mFrontier

Deal found 3/25

$126

Sat 5/245:30 pmDSM - CLT

1 stop5h 01mDelta

Deal found 3/25

$127

Mon 4/71:31 pmDSM - AVL

2 stops31h 14mMultiple Airlines

Deal found 3/24

$130

Fri 5/97:20 pmDSM - RDU

1 stop20h 08mFrontier

Deal found 3/25

$140

Thu 5/158:00 amDSM - CLT

2 stops32h 39mMultiple Airlines

Deal found 3/25

$146

Wed 4/232:12 pmDSM - RDU

1 stop7h 02mAmerican Airlines

Deal found 3/25

$149

Wed 8/137:07 amDSM - MYR

1 stop4h 08mAmerican Airlines

Deal found 3/24

$149

Thu 5/81:27 pmDSM - RDU

2 stops24h 31mMultiple Airlines

Deal found 3/25

$170

Sat 4/125:22 pmDSM - AVL

1 stop5h 17mDelta

Deal found 3/24

$176

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Fri 7/4

6:00 am-11:24 am

1 stop4h 24m

Asheville Regional

Thu 7/10

2:23 pm-7:23 pm

1 stop6h 00m

$224

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Mon 4/7

3:50 pm-10:48 am

1 stop17h 58m

Asheville Regional

Thu 4/24

5:47 pm-10:56 pm

1 stop6h 09m

$234

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 4/11

8:17 pm-6:57 pm

1 stop21h 40m

Charlotte Douglas

Thu 4/17

10:20 pm-7:17 pm

1 stop21h 57m

$240

Des MoinesKnoxville

DSM - TYS

DSMTYS

Des Moines

Thu 5/8

3:59 pm-2:27 pm

1 stop21h 28m

Knoxville McGhee Tyson

Thu 5/15

12:01 pm-1:58 pm

1 stop26h 57m

$240

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Mon 4/28

6:25 pm-11:50 pm

1 stop4h 25m

Asheville Regional

Sat 5/3

6:05 am-10:41 am

1 stop5h 36m

$249

Des MoinesAsheville

DSM - AVL

DSMAVL

Des Moines

Mon 4/7

1:31 pm-9:45 pm

2 stops31h 14m

Asheville Regional

Thu 4/24

5:47 pm-10:56 pm

1 stop6h 09m

$250

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Sat 5/24

6:30 am-12:11 pm

1 stop4h 41m

Charlotte Douglas

Sat 5/31

6:35 pm-10:30 pm

1 stop4h 55m

$253

Des MoinesCharlotte

DSM - CLT

DSMCLT

Des Moines

Fri 5/9

2:28 pm-3:51 pm

2 stops24h 23m

Charlotte Douglas

Fri 5/16

4:32 pm-8:55 pm

1 stop5h 23m

$254

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Tue 4/15

7:20 am-4:16 pm

1 stop7h 56m

Wilmington New Hanover County

Wed 4/23

4:00 pm-10:38 pm

1 stop7h 38m

$259

Des MoinesWilmington

DSM - ILM

DSMILM

Des Moines

Tue 4/15

6:45 am-3:37 pm

2 stops7h 52m

Wilmington New Hanover County

Wed 4/23

5:00 am-1:41 pm

2 stops9h 41m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/25

Showing 1-10 of 57 results

...

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $248). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to NC?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to North Carolina as you normally would.

Rainfall in North Carolina by month

In terms of precipitation, rainfall in North Carolina ranges from 3.0 - 4.2 inches per month. August is typically the wettest month, when rainfall can reach 4.2 in. April is typically the driest time to visit North Carolina when rainfall is around 3.0 in.

Temperature in North Carolina by month

If weather is an important factor for your trip to North Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing North Carolina

To help decide which airline to fly from Des Moines to North Carolina, see what other customers have to say about Southwest, Delta and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

8.1

Very good

4,274 reviews

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta

8.0

Very good

7,891 reviews

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines

7.4

Good

8,608 reviews

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Allegiant Air

7.3

Good

730 reviews

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.1

Very good

4,274 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What airport do you fly from for flights from Des Moines to North Carolina?
Most people fly from Des Moines (DSM) if they book a flight from Des Moines to North Carolina. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.
What are the cheapest airlines to fly from Des Moines to North Carolina one-way?
The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $97. However, be on the lookout for offers from American Airlines and Frontier, as they are both options that can get you from Des Moines to North Carolina for a low price.
What are the most popular routes from Des Moines to North Carolina?
Most travelers choose Des Moines - Myrtle Beach Intl, Des Moines - Charlotte Douglas or Des Moines - Raleigh-Durham when deciding on the best route from Des Moines to North Carolina.
What are the cheapest flights from Des Moines to North Carolina?
On average you can expect to pay $807 for a flight from Des Moines to North Carolina. The cheapest flight overall is $135 while the most popular route, (Des Moines - Myrtle Beach Intl) is currently priced at $260.
Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?
Yes. In addition to deals on Des Moines to North Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to North Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to North Carolina.
Can I find deals for business class flights from Des Moines to North Carolina?
Yes. Cheapflights offers flight deals from Des Moines to North Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to North Carolina?
Currently, August is the cheapest month in which you can book a flight from Des Moines to North Carolina (average of $248). Flying from Des Moines to North Carolina in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Des Moines to North Carolina

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$131	Average$360	FlexibilityNo cancel fee	On-timeN/A
Frontier	Cheapest$140	Average$226	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$196	Average$363	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$229	Average$428	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$312	Average$431	FlexibilityNo cancel fee	On-time63%

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$97+ Cheap flights from Des Moines (DSM) to North Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to North Carolina with Cheapflights

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Cheap flight deals from Des Moines to North Carolina

Keep the following information in mind while searching for Des Moines to North Carolina flight deals. Data was last updated March 26, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Des Moines to North Carolina

Cheapest flights from Des Moines to North CarolinaExplore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to North Carolina that are best for you.

Best time to book a flight from Des Moines to North Carolina

Have a flexible travel schedule? Discover the best time to fly to North Carolina from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to North Carolina

What is the cheapest month to book a flight from Des Moines to North Carolina?

What is the cheapest time of day to fly from DSM to NC?

Find hourly flight availability from Des Moines to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

Rainfall in North Carolina by month

Plan your trip to North Carolina by taking into account the average rainfall totals by month.

Temperature in North Carolina by month

Plan your trip to North Carolina by taking into account the average temperature totals by month.

Reviews of airlines servicing North Carolina

Related info for your journey

Find useful and relevant information for your journey from Des Moines to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to North Carolina?

What are the cheapest airlines to fly from Des Moines to North Carolina one-way?

What are the most popular routes from Des Moines to North Carolina?

What are the cheapest flights from Des Moines to North Carolina?

Can I find deals for flights from Des Moines to North Carolina that include hotel bookings?

How can I find direct flights from Des Moines to North Carolina?

Can I find deals for business class flights from Des Moines to North Carolina?

What is the cheapest month to book a flight from Des Moines to North Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to North Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Des Moines to North Carolina

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Cheapest flights from Des Moines to North Carolina
Explore the most affordable flight options available from Des Moines to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.