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Missouri

$78+ Cheap flights from South Carolina to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from South Carolina to Missouri

Keep the following information in mind while searching for South Carolina to Missouri flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$160
(CheapOair)

One-way from

$78
(Cheapflightsfares)

Popular in

December

Cheapest in

February

Average price

$408

Good round-trip deal

$388 or less
Provider with most accurate pricing for Myrtle Beach Intl-Kansas City flight deals.
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From South Carolina to Missouri
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One-way flight from South Carolina to Missouri
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Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from South Carolina to Missouri.
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Find flight deals from South Carolina to Missouri

Cheapest flights from South Carolina to Missouri
Explore the most affordable flight options available from South Carolina to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/164:21 pmCLT - STL
1 stop8h 53mFrontier
Sun 5/185:45 pmSTL - CLT
1 stop20h 46mFrontier
Deal found 3/30$160
This Booking.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:25 pmCLT - STL
1 stop6h 39mMultiple Airlines
Tue 4/296:10 pmSTL - CLT
1 stop5h 17mMultiple Airlines
Deal found 3/31$162
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/235:43 pmCLT - STL
1 stop24h 32mSpirit Airlines
Sun 4/276:10 pmSTL - CLT
1 stop14h 25mSpirit Airlines
Deal found 3/30$215
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/258:00 amCHS - SGF
1 stop4h 20mDelta
Thu 5/296:56 pmSGF - CHS
1 stop3h 48mDelta
Deal found 3/30$237
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:10 pmCHS - SGF
1 stop4h 47mAmerican Airlines
Sun 5/256:39 pmSGF - CHS
1 stop4h 36mAmerican Airlines
Deal found 3/31$249
This Mytrip deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2810:32 amCHS - MCI
1 stop6h 32mSpirit Airlines
Mon 5/54:59 pmMCI - CHS
1 stop15h 21mSpirit Airlines
Deal found 3/29$249
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/236:10 amCAE - STL
1 stop5h 33mAmerican Airlines
Sun 5/251:45 pmSTL - CAE
1 stop6h 18mAmerican Airlines
Deal found 3/30$254
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2610:57 amCLT - MCI
1 stop5h 29mSpirit Airlines
Sat 5/34:23 pmMCI - CLT
1 stop16h 13mSpirit Airlines
Deal found 3/31$254
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1711:23 amCLT - MCI
1 stop11h 07mMultiple Airlines
Sun 5/184:45 pmMCI - CLT
1 stop24h 21mMultiple Airlines
Deal found 3/30$258
This CheapOair deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/117:38 pmCLT - MCI
1 stop24h 59mFrontier
Sun 4/138:35 pmMCI - CLT
1 stop21h 22mFrontier
Deal found 3/30$260
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/131:35 pmCLT - MCI
Nonstop2h 26mAmerican Airlines
Sat 5/176:15 amMCI - CLT
Nonstop2h 23mAmerican Airlines
Deal found 3/29$263
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/14:20 pmCLT - STL
Nonstop2h 05mSouthwest
Tue 5/610:30 amSTL - CLT
Nonstop1h 50mSouthwest
Deal found 3/31$271

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Carolina to Missouri that are best for you.

Fly from

South Carolina

Fly to

Missouri

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 5/16

4:21 pm-12:14 am

1 stop8h 53m

Lambert-St Louis

Sun 5/18

5:45 pm-3:31 pm

1 stop20h 46m

$160

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 4/24

6:25 pm-12:04 am

1 stop6h 39m

Lambert-St Louis

Tue 4/29

6:10 pm-12:27 am

1 stop5h 17m

$162

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Tue 4/29

6:58 am-5:15 pm

1 stop11h 17m

Lambert-St Louis

Tue 5/6

6:10 pm-8:40 pm

2 stops25h 30m

$200

CharlestonSpringfield

CHS - SGF

CHSSGF

Charleston

Sun 5/25

8:00 am-11:20 am

1 stop4h 20m

Springfield-Branson

Thu 5/29

6:56 pm-11:44 pm

1 stop3h 48m

$237

CharlestonSpringfield

CHS - SGF

CHSSGF

Charleston

Sat 5/17

6:10 pm-9:57 pm

1 stop4h 47m

Springfield-Branson

Sun 5/25

6:39 pm-12:15 am

1 stop4h 36m

$249

CharlestonKansas City

CHS - MCI

CHSMCI

Charleston

Mon 4/28

10:32 am-4:04 pm

1 stop6h 32m

Kansas City

Mon 5/5

4:59 pm-9:20 am

1 stop15h 21m

$249

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Fri 5/23

6:10 am-10:43 am

1 stop5h 33m

Lambert-St Louis

Sun 5/25

1:45 pm-9:03 pm

1 stop6h 18m

$254

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 4/26

10:57 am-3:26 pm

1 stop5h 29m

Kansas City

Sat 5/3

4:23 pm-9:36 am

1 stop16h 13m

$254

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Sat 5/17

11:23 am-9:30 pm

1 stop11h 07m

Kansas City

Sun 5/18

4:45 pm-6:06 pm

1 stop24h 21m

$258

CharlotteKansas City

CLT - MCI

CLTMCI

Charlotte Douglas

Fri 4/11

7:38 pm-7:37 pm

1 stop24h 59m

Kansas City

Sun 4/13

8:35 pm-6:57 pm

1 stop21h 22m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Missouri

What is the cheapest month to book a flight from South Carolina to Missouri?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MO?

Find hourly flight availability from South Carolina to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 31, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from South Carolina to Missouri to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,275 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,899 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,614 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Allegiant Air
7.3
Good
731 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.2

Food

7.1

Overall

8.0

Comfort

8.1

Entertainment

7.6

Crew

8.7

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Missouri one-way?

    One-way options have recently been found by users for as low as $78 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $82 and Southwest from $128 one-way.

  • Can I find deals for flights from South Carolina to Missouri that include hotel bookings?

    Yes. In addition to deals on South Carolina to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Missouri.

  • Can I find deals for business class flights from South Carolina to Missouri?

    Yes. Cheapflights offers flight deals from South Carolina to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Missouri?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Missouri (average of $311). Flying from South Carolina to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from South Carolina to Missouri

Discover the top 5 airlines that operate flights from South Carolina to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$139Average$366FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$139Average$246FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$170Average$379FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$174Average$366FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$286Average$389FlexibilityNo cancel feeOn-time63%
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