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$72+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated February 20, 2025.

Round-trip from

$210
(Booking.com)

One-way from

$72
(Mytrip)
From Portland to Missouri
Search Deals
One-way flight from Portland to Missouri
Search Deals

Find flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/109:29 pmPWM - STL
1 stop27h 37mFrontier
Thu 5/155:47 pmSTL - PWM
1 stop25h 53mFrontier
Deal found 2/20$210
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/145:30 amPWM - SGF
1 stop6h 55mDelta
Sun 3/233:29 pmSGF - PWM
1 stop7h 29mDelta
Deal found 2/19$269
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2812:06 pmPWM - MCI
1 stop23h 29mMultiple Airlines
Sun 3/212:15 pmMCI - PWM
2 stops28h 23mMultiple Airlines
Deal found 2/19$291
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/102:02 pmPWM - STL
1 stop8h 25mAmerican Airlines
Tue 5/134:37 pmSTL - PWM
1 stop6h 18mAmerican Airlines
Deal found 2/19$317
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:30 pmPWM - SGF
1 stop6h 22mAmerican Airlines
Tue 8/126:40 pmSGF - PWM
1 stop4h 55mAmerican Airlines
Deal found 2/20$324
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/124:30 pmPWM - STL
1 stop5h 22mDelta
Sat 3/156:50 amSTL - PWM
1 stop4h 26mDelta
Deal found 2/20$348
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2912:30 pmPWM - STL
2 stops8h 25mSouthwest
Fri 5/95:45 amSTL - PWM
1 stop4h 20mSouthwest
Deal found 2/20$357
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:15 amPWM - MCI
1 stop5h 37mDelta
Sun 3/236:15 amMCI - PWM
1 stop5h 01mDelta
Deal found 2/19$392
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/105:38 amPWM - MCI
1 stop7h 17mAmerican Airlines
Sat 4/125:07 amMCI - PWM
2 stops9h 11mAmerican Airlines
Deal found 2/19$397
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/106:05 amPWM - STL
1 stop7h 14mUnited Airlines
Tue 5/131:10 pmSTL - PWM
2 stops9h 49mUnited Airlines
Deal found 2/19$403
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/164:40 pmPWM - MCI
1 stop7h 55mSouthwest
Mon 5/195:50 amMCI - PWM
2 stops9h 05mSouthwest
Deal found 2/19$512
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/136:00 amPWM - SGF
1 stop5h 50mUnited Airlines
Thu 3/204:59 pmSGF - PWM
2 stops16h 38mUnited Airlines
Deal found 2/19$525

Find flights from Portland to Missouri within your budget

Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/10

9:29 pm-12:06 am

1 stop27h 37m

Lambert-St Louis

Thu 5/15

5:47 pm-8:40 pm

1 stop25h 53m

$210

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Fri 3/14

5:30 am-11:25 am

1 stop6h 55m

Springfield-Branson

Sun 3/23

3:29 pm-11:58 pm

1 stop7h 29m

$269

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/10

2:02 pm-9:27 pm

1 stop8h 25m

Lambert-St Louis

Tue 5/13

4:37 pm-11:55 pm

1 stop6h 18m

$317

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 8/7

6:30 pm-11:52 pm

1 stop6h 22m

Springfield-Branson

Tue 8/12

6:40 pm-12:35 am

1 stop4h 55m

$324

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 3/12

4:30 pm-8:52 pm

1 stop5h 22m

Lambert-St Louis

Sat 3/15

6:50 am-12:16 pm

1 stop4h 26m

$348

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 4/29

12:30 pm-7:55 pm

2 stops8h 25m

Lambert-St Louis

Fri 5/9

5:45 am-11:05 am

1 stop4h 20m

$357

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 3/19

6:15 am-10:52 am

1 stop5h 37m

Kansas City

Sun 3/23

6:15 am-12:16 pm

1 stop5h 01m

$392

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Thu 4/10

5:38 am-11:55 am

1 stop7h 17m

Kansas City

Sat 4/12

5:07 am-3:18 pm

2 stops9h 11m

$397

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/10

6:05 am-12:19 pm

1 stop7h 14m

Lambert-St Louis

Tue 5/13

1:10 pm-11:59 pm

2 stops9h 49m

$403

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Fri 5/16

4:40 pm-11:35 pm

1 stop7h 55m

Kansas City

Mon 5/19

5:50 am-3:55 pm

2 stops9h 05m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 19 results
1
2

Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Portland to Missouri

Get recent, data-driven insights about flights from Portland to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from Portland, Maine to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 20, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Portland to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Frontier
6.0
Okay
3,355 reviews
Southwest
8.1
Very good
4,411 reviews

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Comfort

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $72 on Frontier. Other airlines that offer cheap prices include American Airlines from $169 and Delta from $204 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Kansas City, Portland - Lambert-St Louis or Portland - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$459FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$547FlexibilityNo cancel feeOn-time69%
DeltaCheapest$292Average$462FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$351Average$508FlexibilityNo cancel feeOn-time63%
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