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$159+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Mar 30 — Apr 61
Sun 3/30
Sun 4/6
1 adult, Economy
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Cheap flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated March 25, 2025.

Round-trip from

$268
(Booking.com)

One-way from

$159
(American Airlines)
From Portland to Missouri
Search Deals
One-way flight from Portland to Missouri
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Find flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1210:12 amPWM - STL
1 stop14h 34mFrontier
Sun 4/134:57 pmSTL - PWM
1 stop20h 13mFrontier
Deal found 3/24$268
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2812:08 pmPWM - STL
1 stop12h 43mAmerican Airlines
Wed 6/41:59 pmSTL - PWM
1 stop8h 06mAmerican Airlines
Deal found 3/24$291
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/76:30 pmPWM - SGF
1 stop6h 22mAmerican Airlines
Tue 8/126:40 pmSGF - PWM
1 stop4h 55mAmerican Airlines
Deal found 3/24$294
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:00 pmPWM - STL
2 stops7h 26mDelta
Tue 5/135:40 pmSTL - PWM
1 stop5h 19mDelta
Deal found 3/24$322
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:45 amPWM - MCI
1 stop8h 16mAmerican Airlines
Tue 6/33:51 pmMCI - PWM
1 stop6h 14mAmerican Airlines
Deal found 3/24$335
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:30 amPWM - MCI
1 stop7h 40mDelta
Sat 5/315:26 pmMCI - PWM
1 stop5h 33mDelta
Deal found 3/24$336
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/105:30 amPWM - STL
2 stops8h 05mSouthwest
Mon 6/165:05 pmSTL - PWM
1 stop6h 00mSouthwest
Deal found 3/24$357
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/96:15 amPWM - STL
2 stops10h 32mUnited Airlines
Mon 4/148:00 amSTL - PWM
1 stop5h 53mUnited Airlines
Deal found 3/24$374
This United deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/610:05 amPWM - SGF
2 stops11h 12mUnited Airlines
Tue 8/125:45 amSGF - PWM
2 stops12h 42mUnited Airlines
Deal found 3/24$440
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/711:45 amPWM - MCI
1 stop7h 00mUnited Airlines
Thu 4/103:29 pmMCI - PWM
1 stop5h 06mUnited Airlines
Deal found 3/24$507
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/75:30 pmPWM - MCI
2 stops7h 35mSouthwest
Thu 4/105:10 amMCI - PWM
1 stop7h 30mSouthwest
Deal found 3/24$512
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:16 pmPWM - STL
3 stops15h 59mMultiple Airlines
Sun 5/1110:10 amSTL - PWM
2 stops26h 57mMultiple Airlines
Deal found 3/24$606

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 4/12

10:12 am-11:46 pm

1 stop14h 34m

Lambert-St Louis

Sun 4/13

4:57 pm-2:10 pm

1 stop20h 13m

$268

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/28

12:08 pm-11:51 pm

1 stop12h 43m

Lambert-St Louis

Wed 6/4

1:59 pm-11:05 pm

1 stop8h 06m

$291

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Thu 8/7

6:30 pm-11:52 pm

1 stop6h 22m

Springfield-Branson

Tue 8/12

6:40 pm-12:35 am

1 stop4h 55m

$294

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 5/10

5:00 pm-11:26 pm

2 stops7h 26m

Lambert-St Louis

Tue 5/13

5:40 pm-11:59 pm

1 stop5h 19m

$322

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 5/28

7:45 am-3:01 pm

1 stop8h 16m

Kansas City

Tue 6/3

3:51 pm-11:05 pm

1 stop6h 14m

$335

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Tue 5/27

5:30 am-12:10 pm

1 stop7h 40m

Kansas City

Sat 5/31

5:26 pm-11:59 pm

1 stop5h 33m

$336

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 6/10

5:30 am-12:35 pm

2 stops8h 05m

Lambert-St Louis

Mon 6/16

5:05 pm-12:05 am

1 stop6h 00m

$357

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 4/9

6:15 am-3:47 pm

2 stops10h 32m

Lambert-St Louis

Tue 4/15

3:40 pm-9:35 pm

1 stop4h 55m

$374

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

Wed 8/6

10:05 am-8:17 pm

2 stops11h 12m

Springfield-Branson

Tue 8/12

5:45 am-7:27 pm

2 stops12h 42m

$440

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Mon 4/7

11:45 am-5:45 pm

1 stop7h 00m

Kansas City

Thu 4/10

3:29 pm-9:35 pm

1 stop5h 06m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 19 results
1
2

Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.

When flying from Portland, Maine to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 25, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Portland to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,272 reviews
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,890 reviews
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,605 reviews
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,273 reviews
Southwest
8.0
Very good
4,272 reviews

Boarding

8.2

Comfort

8.0

Entertainment

7.6

Overall

8.0

Food

7.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $159 on American Airlines. Other airlines that offer cheap prices include United Airlines from $162 and Southwest from $444 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Lambert-St Louis, Portland - Springfield-Branson or Portland - Kansas City as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Portland to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$464FlexibilityNo cancel feeOn-time71%
DeltaCheapest$255Average$430FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$552FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$351Average$508FlexibilityNo cancel feeOn-time63%
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