HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$119+ Cheap flights from Portland, ME (PWM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
abr. 20 — abr. 271
dom. 4/20
dom. 4/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Portland to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Portland to Missouri

Keep the following information in mind while searching for Portland to Missouri flight deals. Data was last updated abril 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$198
(Booking.com)

One-way from

$119
(Frontier)

Popular in

April

Cheapest in

January

Average price

$780
Provider with most accurate pricing for Portland-Kansas City flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Kansas City flights.
Search Deals
From Portland to Missouri
Search Deals
One-way flight from Portland to Missouri
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Portland to Missouri

Cheapest flights from Portland to Missouri
Explore the most affordable flight options available from Portland to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 15, 2025.

This Booking.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 5/118:23 pmPWM - STL
1 stop28h 43mFrontier
mié. 5/145:45 pmSTL - PWM
1 stop25h 44mFrontier
Deal found 4/15$198
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2812:08 pmPWM - STL
1 stop10h 44mAmerican Airlines
mié. 6/41:59 pmSTL - PWM
1 stop8h 06mAmerican Airlines
Deal found 4/14$275
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/105:00 pmPWM - STL
1 stop5h 31mDelta
mar. 5/1311:32 amSTL - PWM
2 stops10h 49mDelta
Deal found 4/14$290
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/281:40 pmPWM - MCI
1 stop7h 40mDelta
mar. 6/33:48 pmMCI - PWM
1 stop7h 11mDelta
Deal found 4/14$299
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/295:20 amPWM - SGF
1 stop7h 03mDelta
sáb. 5/33:30 pmSGF - PWM
1 stop7h 29mDelta
Deal found 4/14$319
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/304:56 pmPWM - MCI
1 stop7h 18mUnited Airlines
sáb. 8/25:40 pmMCI - PWM
1 stop5h 19mUnited Airlines
Deal found 4/15$335
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/410:35 amPWM - MCI
1 stop5h 40mSouthwest
lun. 9/85:35 amMCI - PWM
2 stops8h 00mSouthwest
Deal found 4/14$340
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/22:30 pmPWM - STL
1 stop6h 40mSouthwest
mar. 5/66:15 amSTL - PWM
1 stop4h 15mSouthwest
Deal found 4/15$366
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2811:07 amPWM - MCI
2 stops8h 58mAmerican Airlines
mar. 6/35:45 pmMCI - PWM
1 stop5h 10mAmerican Airlines
Deal found 4/14$378
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/75:18 pmPWM - SGF
1 stop5h 22mAmerican Airlines
mié. 8/137:11 amSGF - PWM
1 stop6h 57mAmerican Airlines
Deal found 4/14$384
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/76:00 amPWM - SGF
2 stops17h 00mUnited Airlines
mié. 8/1311:23 amSGF - PWM
2 stops11h 36mUnited Airlines
Deal found 4/15$512
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/293:28 pmPWM - STL
1 stop8h 47mUnited Airlines
sáb. 5/38:00 amSTL - PWM
1 stop5h 38mUnited Airlines
Deal found 4/14$527

Cheapflights Fare Finder

Customize your flight search to find flights from Portland to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 15, 2025.
Use the filters below to find and compare flights from Portland to Missouri that are best for you.

Fly from

Portland

Fly to

Missouri

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

dom. 5/11

8:23 pm-12:06 am

1 stop28h 43m

Lambert-St Louis

mié. 5/14

5:45 pm-8:29 pm

1 stop25h 44m

$198

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

mié. 5/28

12:08 pm-9:52 pm

1 stop10h 44m

Lambert-St Louis

mié. 6/4

1:59 pm-11:05 pm

1 stop8h 06m

$275

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

sáb. 5/10

5:00 pm-9:31 pm

1 stop5h 31m

Lambert-St Louis

mar. 5/13

11:32 am-11:21 pm

2 stops10h 49m

$290

PortlandKansas City

PWM - MCI

PWMMCI

Portland

mié. 5/28

1:40 pm-8:20 pm

1 stop7h 40m

Kansas City

mar. 6/3

3:48 pm-11:59 pm

1 stop7h 11m

$299

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

mar. 4/29

5:20 am-11:23 am

1 stop7h 03m

Springfield-Branson

sáb. 5/3

3:30 pm-11:59 pm

1 stop7h 29m

$319

PortlandKansas City

PWM - MCI

PWMMCI

Portland

mié. 7/30

4:56 pm-11:14 pm

1 stop7h 18m

Kansas City

sáb. 8/2

5:40 pm-11:59 pm

1 stop5h 19m

$335

PortlandKansas City

PWM - MCI

PWMMCI

Portland

jue. 9/4

10:35 am-3:15 pm

1 stop5h 40m

Kansas City

lun. 9/8

5:35 am-2:35 pm

2 stops8h 00m

$340

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

vie. 5/2

2:30 pm-8:10 pm

1 stop6h 40m

Lambert-St Louis

mar. 5/6

6:15 am-11:30 am

1 stop4h 15m

$366

PortlandKansas City

PWM - MCI

PWMMCI

Portland

mié. 5/28

11:07 am-7:05 pm

2 stops8h 58m

Kansas City

mar. 6/3

5:45 pm-11:55 pm

1 stop5h 10m

$378

PortlandSpringfield

PWM - SGF

PWMSGF

Portland

jue. 8/7

5:18 pm-9:40 pm

1 stop5h 22m

Springfield-Branson

mié. 8/13

7:11 am-3:08 pm

1 stop6h 57m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Showing 1-10 of 23 results
1
2
3

Best time to book a flight from Portland to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Missouri

What is the cheapest month to book a flight from Portland, Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to MO?

Find hourly flight availability from Portland to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 15, 2025.

When flying from Portland, Maine to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated abril 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and United Airlines from Portland to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,279 reviews
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,917 reviews
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,658 reviews
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,281 reviews
Southwest
8.0
Very good
4,279 reviews

Comfort

8.0

Overall

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Portland to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Portland to Missouri?

    Located just 2.9 mi from the city center, Portland (PWM) is the airport most travelers will use when flying to Missouri from Portland.

  • What are the cheapest airlines to fly from Portland, Maine to Missouri one-way?

    One-way options have recently been found by users for as low as $119 on Frontier. Other airlines that offer cheap prices include Delta from $168 and Southwest from $205 one-way.

  • What are the most popular routes from Portland, Maine to Missouri?

    When deciding which route to take from Portland, Maine to Missouri consider Portland - Lambert-St Louis, Portland - Kansas City or Portland - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Portland to Missouri that include hotel bookings?

    Yes. In addition to deals on Portland to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Missouri.

  • Can I find deals for business class flights from Portland to Missouri?

    Yes. Cheapflights offers flight deals from Portland to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Portland, Maine to Missouri (average of $311). Flying from Portland, Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Portland to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Boston to Orlando flights
Boston to Los Angeles flights
Boston to Las Vegas flights
Boston to Fort Lauderdale flights
Boston to Miami flights
Boston to Dulles Intl flights
Boston to O'Hare Intl flights
Boston to Tampa flights
Boston to San Francisco flights
Boston to Seattle flights
Boston to Sky Harbor Intl flights
Boston to Dallas/Fort Worth flights
Boston to Reagan-National flights
Boston to Denver flights
Boston to Baltimore flights
Boston to Hobby flights
Boston to West Palm Beach flights
Boston to Newark flights
Boston to Philadelphia flights
Boston to LaGuardia flights
Boston to Nashville flights
Boston to Atlanta flights
Boston to Fort Myers flights
Boston to Charleston flights
Boston to Charlotte flights
Boston to Austin flights
Boston to George Bush Intcntl flights
Boston to New Orleans flights
Boston to John F Kennedy Intl flights
Boston to Minneapolis flights
Boston to San Diego flights
Boston to Raleigh flights
Boston to Midway flights
Boston to Salt Lake City flights
Boston to Portland flights
Boston to Pittsburgh flights
Boston to Savannah flights
Boston to Myrtle Beach flights
Boston to Detroit flights
Boston to Cincinnati flights
Boston to Cleveland flights
Boston to Richmond flights
Boston to Columbus flights
Boston to Honolulu flights
Boston to Indianapolis flights
Boston to Sarasota flights
Boston to Ontario flights
Boston to Jacksonville flights
Boston to Burbank flights
Boston to Kansas City flights

Top 4 airlines flying from Portland to Missouri

Discover the top 4 airlines that operate flights from Portland to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$449FlexibilityNo cancel feeOn-time71%
DeltaCheapest$255Average$434FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$267Average$531FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$351Average$509FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.