How popular is this Pennsylvania to Missouri flight route?

Flights from Pennsylvania to Missouri have been viewed 39 times in the past calendar month.

How long is the flight from Pennsylvania to Missouri?

A quick flight from Pennsylvania to Missouri can take about 3h 02m. Spirit Airlines provides one of the quickest options available for as low as $241. There are 869 mi between Pennsylvania and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Pennsylvania to Missouri one-way?

One-way options have recently been found by users for as low as $70 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $80 and American Airlines from $89 one-way.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?

Yes. In addition to deals on Pennsylvania to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Pennsylvania to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Missouri.

Can I find deals for business class flights from Pennsylvania to Missouri?

Yes. Cheapflights offers flight deals from Pennsylvania to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$51+ Flights from Pennsylvania to Missouri

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Find cheap flights from Pennsylvania to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Pennsylvania to Missouri

Cheapest flights from Pennsylvania to Missouri
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Wed 12/3110:30 pmEWR - STL

1 stop12h 10mFrontier

Thu 1/110:42 amSTL - EWR

1 stop9h 53mFrontier

Deal found 12/12

$188

Wed 12/3110:30 pmEWR - STL

2 stops36h 15mMultiple Airlines

Wed 1/148:32 pmSTL - EWR

1 stop10h 21mMultiple Airlines

Deal found 12/12

$214

Wed 12/315:23 pmEWR - MCI

1 stop24h 47mMultiple Airlines

Mon 1/511:38 amMCI - EWR

1 stop19h 22mMultiple Airlines

Deal found 12/13

$238

Wed 12/319:59 pmEWR - STL

Nonstop2h 58mUnited Airlines

Wed 1/147:00 amSTL - EWR

Nonstop2h 37mUnited Airlines

Deal found 12/12

$241

Thu 12/259:54 pmEWR - STL

Nonstop2h 49mUnited Airlines

Wed 12/315:02 pmSTL - EWR

1 stop5h 13mUnited Airlines

Deal found 12/12

$251

Wed 12/316:00 amEWR - STL

1 stop7h 27mUnited Airlines

Wed 12/315:02 pmSTL - EWR

1 stop5h 13mUnited Airlines

Deal found 12/12

$261

Thu 12/255:50 pmIAD - STL

Nonstop2h 32mUnited Airlines

Thu 1/18:15 amSTL - IAD

Nonstop2h 09mUnited Airlines

Deal found 12/13

$262

Wed 12/3111:30 amEWR - STL

1 stop5h 57mUnited Airlines

Thu 1/17:00 amSTL - EWR

Nonstop2h 34mUnited Airlines

Deal found 12/12

$271

Thu 12/258:30 amDCA - STL

1 stop5h 44mAmerican Airlines

Wed 12/316:02 amSTL - DCA

Nonstop2h 08mAmerican Airlines

Deal found 12/13

$272

Thu 12/255:31 pmIAD - MCI

1 stop5h 19mUnited Airlines

Thu 1/15:46 pmMCI - IAD

Nonstop2h 34mUnited Airlines

Deal found 12/14

$276

Thu 12/181:24 pmJFK - STL

1 stop19h 48mFrontier

Sun 1/410:10 pmSTL - JFK

1 stop30h 19mFrontier

Deal found 12/12

$282

Wed 12/319:10 amLGA - STL

Nonstop2h 54mAmerican Airlines

Wed 1/143:30 pmSTL - LGA

Nonstop2h 29mAmerican Airlines

Deal found 12/12

$283

Best flights from Pennsylvania to Missouri
Discover carefully curated flight deals from Pennsylvania to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 14, 2025.

Thu 1/86:59 pmEWR - MCI

1 stop16h 32mSpirit Airlines

Mon 1/1211:26 amMCI - EWR

2 stops11h 04mSpirit Airlines

Deal found 12/12

$163

Thu 2/195:00 amEWR - MCI

1 stop11h 29mMultiple Airlines

Sun 2/2210:14 amMCI - EWR

1 stop12h 33mMultiple Airlines

Deal found 12/13

$201

Sun 3/810:30 pmEWR - MCI

1 stop18h 50mFrontier

Wed 3/1111:40 amMCI - EWR

1 stop12h 23mFrontier

Deal found 12/12

$241

Tue 1/139:57 pmEWR - STL

Nonstop3h 02mUnited Airlines

Sat 1/177:00 amSTL - EWR

Nonstop2h 37mUnited Airlines

Deal found 12/13

$241

Sat 2/2110:30 amDCA - STL

1 stop7h 25mSouthwest

Wed 2/2510:15 amSTL - DCA

2 stops6h 45mSouthwest

Deal found 12/11

$260

Tue 1/136:00 amEWR - STL

1 stop6h 05mDelta

Wed 1/146:35 amSTL - EWR

1 stop4h 34mDelta

Deal found 12/12

$261

Sat 1/1011:59 amDCA - MCI

1 stop7h 04mAmerican Airlines

Tue 1/1310:43 amMCI - DCA

Nonstop2h 35mAmerican Airlines

Deal found 12/14

$279

Fri 2/275:00 amEWR - MCI

1 stop11h 29mSpirit Airlines

Mon 3/94:24 pmMCI - EWR

1 stop6h 25mSpirit Airlines

Deal found 12/14

$251

Wed 12/3110:15 amEWR - STL

1 stop7h 12mUnited Airlines

Wed 1/147:00 amSTL - EWR

Nonstop2h 37mUnited Airlines

Deal found 12/12

$251

Wed 1/711:00 amDCA - STL

2 stops7h 05mSouthwest

Sat 1/107:40 amSTL - DCA

1 stop4h 40mSouthwest

Deal found 12/13

$260

Sat 1/176:00 amEWR - STL

1 stop4h 39mDelta

Sun 1/187:10 amSTL - EWR

1 stop6h 47mDelta

Deal found 12/13

$261

Sat 1/105:50 pmIAD - STL

Nonstop2h 37mUnited Airlines

Sat 1/179:57 amSTL - IAD

1 stop5h 03mUnited Airlines

Deal found 12/13

$261

Sat 1/178:00 amDCA - STL

1 stop7h 48mFrontier

Mon 1/197:36 pmSTL - DCA

1 stop25h 23mFrontier

Deal found 12/13

$291

Sat 1/1010:19 pmEWR - MCI

2 stops37h 12mSpirit Airlines

Sat 1/175:04 pmMCI - EWR

1 stop15h 56mSpirit Airlines

Deal found 12/14

$265

Fri 1/1612:53 pmLGA - STL

Nonstop3h 04mAmerican Airlines

Mon 1/1911:27 amSTL - LGA

Nonstop2h 28mAmerican Airlines

Deal found 12/14

$293

Mon 2/233:55 pmDCA - STL

1 stop5h 00mSouthwest

Wed 2/253:05 pmSTL - DCA

Nonstop2h 00mSouthwest

Deal found 12/12

$275

Tue 1/136:15 pmIAD - STL

1 stop6h 24mDelta

Thu 1/156:35 amSTL - IAD

1 stop4h 14mDelta

Deal found 12/14

$285

Sat 1/108:40 amIAD - STL

Nonstop2h 33mUnited Airlines

Mon 1/128:30 amSTL - IAD

Nonstop2h 10mUnited Airlines

Deal found 12/12

$265

Fri 2/277:31 amLGA - STL

1 stop6h 15mAmerican Airlines

Sun 3/13:32 pmSTL - LGA

Nonstop2h 27mAmerican Airlines

Deal found 12/14

$303

Sat 1/1012:45 pmDCA - STL

2 stops8h 25mSouthwest

Mon 1/128:20 amSTL - DCA

Nonstop1h 55mSouthwest

Deal found 12/12

$280

Sat 1/178:00 amIAD - MCI

1 stop5h 42mDelta

Mon 1/196:18 pmMCI - IAD

1 stop5h 06mDelta

Deal found 12/13

$287

Fri 2/68:35 amEWR - STL

Nonstop3h 06mUnited Airlines

Sat 2/76:06 pmSTL - EWR

Nonstop2h 44mUnited Airlines

Deal found 12/13

$267

Sat 1/109:55 amLGA - MCI

1 stop7h 14mMultiple Airlines

Sat 1/175:04 pmMCI - LGA

2 stops17h 16mMultiple Airlines

Deal found 12/13

$356

Sun 1/187:55 amJFK - STL

1 stop8h 09mAmerican Airlines

Thu 1/229:54 amSTL - JFK

1 stop4h 03mAmerican Airlines

Deal found 12/13

$313

Fri 1/1612:00 pmDCA - STL

Nonstop2h 35mSouthwest

Tue 1/206:20 amSTL - DCA

2 stops8h 05mSouthwest

Deal found 12/13

$287

Mon 3/211:48 amEWR - STL

1 stop6h 54mDelta

Wed 3/47:10 amSTL - EWR

1 stop4h 49mDelta

Deal found 12/13

$287

Thu 12/258:15 amIAD - STL

1 stop7h 11mUnited Airlines

Thu 1/18:15 amSTL - IAD

Nonstop2h 09mUnited Airlines

Deal found 12/13

$272

Fri 2/275:10 pmJFK - STL

1 stop5h 31mAmerican Airlines

Sun 3/17:00 amSTL - JFK

1 stop5h 29mAmerican Airlines

Deal found 12/14

$313

Fri 1/166:35 pmDCA - STL

Nonstop2h 30mSouthwest

Sun 1/1810:15 amSTL - DCA

2 stops6h 45mSouthwest

Deal found 12/12

$287

Sun 1/186:00 amEWR - STL

1 stop4h 39mDelta

Thu 1/227:10 amSTL - EWR

1 stop6h 44mDelta

Deal found 12/13

$287

Last-minute flights from Pennsylvania to Missouri
Discover last-minute flight deals from Pennsylvania to Missouri. Data last updated December 14, 2025 and is based on user searches.

Wed 1/75:51 amEWR - MCI

1 stop12h 19mSpirit Airlines

Mon 1/1211:26 amMCI - EWR

1 stop8h 48mSpirit Airlines

Deal found 12/13

$143

Thu 1/85:25 amEWR - STL

1 stop10h 23mMultiple Airlines

Sun 1/115:11 pmSTL - EWR

1 stop15h 49mMultiple Airlines

Deal found 12/12

$144

Thu 1/86:59 pmEWR - MCI

1 stop16h 32mSpirit Airlines

Mon 1/1211:26 amMCI - EWR

1 stop26h 44mSpirit Airlines

Deal found 12/14

$147

Sat 1/103:30 pmEWR - STL

1 stop8h 03mMultiple Airlines

Wed 2/118:17 pmSTL - EWR

1 stop27h 51mMultiple Airlines

Deal found 12/12

$143

Mon 1/126:00 pmEWR - STL

1 stop29h 34mMultiple Airlines

Mon 1/198:32 pmSTL - EWR

1 stop25h 58mMultiple Airlines

Deal found 12/13

$139

Tue 1/135:40 pmEWR - STL

1 stop14h 11mMultiple Airlines

Sat 1/178:32 pmSTL - EWR

1 stop27h 41mMultiple Airlines

Deal found 12/13

$130

Fri 1/165:40 pmEWR - STL

1 stop14h 11mMultiple Airlines

Mon 1/198:32 pmSTL - EWR

1 stop25h 58mMultiple Airlines

Deal found 12/13

$127

Fri 1/236:00 amEWR - MCI

1 stop6h 50mFrontier

Sun 1/2511:00 amMCI - EWR

1 stop9h 35mFrontier

Deal found 12/12

$128

Fri 1/2310:30 pmEWR - STL

1 stop9h 21mFrontier

Sun 1/255:42 pmSTL - EWR

1 stop16h 07mFrontier

Deal found 12/12

$141

Fri 1/3011:44 amEWR - STL

1 stop12h 49mFrontier

Tue 2/35:42 pmSTL - EWR

1 stop16h 07mFrontier

Deal found 12/12

$133

Fri 1/3010:30 pmEWR - STL

1 stop9h 21mMultiple Airlines

Mon 2/25:42 pmSTL - EWR

1 stop15h 18mMultiple Airlines

Deal found 12/13

$142

Fri 1/3012:00 pmEWR - STL

2 stops19h 51mMultiple Airlines

Tue 2/35:42 pmSTL - EWR

1 stop16h 07mMultiple Airlines

Deal found 12/12

$150

One-way flights from Pennsylvania to Missouri
Search for one-way flight options from Pennsylvania to Missouri. Find affordable one-way fares based on user searches. Data last updated December 14, 2025.

Tue 1/205:40 pmEWR - STL

1 stop14h 11mMultiple Airlines

Deal found 12/12

$51

Tue 1/2710:30 pmEWR - STL

1 stop9h 21mFrontier

Deal found 12/12

$56

Tue 1/135:40 pmEWR - STL

1 stop14h 11mMultiple Airlines

Deal found 12/12

$57

Fri 1/1610:08 pmIAD - STL

1 stop9h 43mFrontier

Deal found 12/14

$62

Fri 1/2310:30 pmEWR - STL

1 stop9h 21mFrontier

Deal found 12/14

$62

Wed 2/118:00 amDCA - MCI

1 stop8h 44mFrontier

Deal found 12/14

$63

Wed 2/118:00 amDCA - STL

1 stop8h 53mFrontier

Deal found 12/14

$63

Fri 1/3010:30 pmEWR - STL

1 stop9h 21mFrontier

Deal found 12/14

$63

Thu 1/86:00 amIAD - STL

1 stop9h 48mFrontier

Deal found 12/14

$64

Sat 2/281:00 pmDCA - MCI

1 stop7h 46mFrontier

Deal found 12/14

$64

Sat 1/248:00 amDCA - STL

1 stop7h 46mFrontier

Deal found 12/14

$64

Sun 2/85:40 pmEWR - STL

1 stop14h 11mMultiple Airlines

Deal found 12/13

$64

Find flight deals from Pennsylvania to Missouri

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$108 (Kiwi.com)
One-way from	$51 (Kiwi.com)
Popular in	May
Cheapest in	August
Average price	$462
Good round-trip deal	$348 or less
Good one-way deal	$200 or less

Provider with most accurate pricing for Philadelphia-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Philadelphia-Lambert-St Louis flights.

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From Pennsylvania to Missouri

Search Deals

One-way flight from Pennsylvania to Missouri

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($35 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Pennsylvania to Missouri.

Search Deals

Price to beat on a one-way flight from Pennsylvania to Missouri.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Thu 1/8

6:59 pm-10:31 am

1 stop16h 32m

Kansas City

Mon 1/12

11:26 am-11:30 pm

2 stops11h 04m

$163

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Thu 2/19

5:00 am-3:29 pm

1 stop11h 29m

Kansas City

Sun 2/22

10:14 am-11:47 pm

1 stop12h 33m

$201

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Sun 3/8

10:30 pm-4:20 pm

1 stop18h 50m

Kansas City

Wed 3/11

11:40 am-1:03 am

1 stop12h 23m

$241

NewarkSt. Louis

EWR - STL

EWRSTL

Newark

Tue 1/13

9:57 pm-11:59 pm

Nonstop3h 02m

Lambert-St Louis

Sat 1/17

7:00 am-10:37 am

Nonstop2h 37m

$241

NewarkKansas City

EWR - MCI

EWRMCI

Newark

Fri 2/27

5:00 am-3:29 pm

1 stop11h 29m

Kansas City

Mon 3/9

4:24 pm-11:49 pm

1 stop6h 25m

$251

NewarkSt. Louis

EWR - STL

EWRSTL

Newark

Wed 12/31

10:15 am-4:27 pm

1 stop7h 12m

Lambert-St Louis

Wed 1/14

7:00 am-10:37 am

Nonstop2h 37m

$251

Washington, D.C.St. Louis

DCA - STL

DCASTL

Washington, D.C. Reagan-National

Sat 2/21

10:30 am-4:55 pm

1 stop7h 25m

Lambert-St Louis

Wed 2/25

10:15 am-6:00 pm

2 stops6h 45m

$260

Washington, D.C.St. Louis

DCA - STL

DCASTL

Washington, D.C. Reagan-National

Wed 1/7

11:00 am-5:05 pm

2 stops7h 05m

Lambert-St Louis

Sat 1/10

7:40 am-1:20 pm

1 stop4h 40m

$260

NewarkSt. Louis

EWR - STL

EWRSTL

Newark

Tue 1/13

6:00 am-11:05 am

1 stop6h 05m

Lambert-St Louis

Wed 1/14

6:35 am-12:09 pm

1 stop4h 34m

$261

NewarkSt. Louis

EWR - STL

EWRSTL

Newark

Sat 1/17

6:00 am-9:39 am

1 stop4h 39m

Lambert-St Louis

Sun 1/18

7:10 am-2:57 pm

1 stop6h 47m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results

...

Best time to book a flight from Pennsylvania to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Missouri

What is the cheapest month to book a flight from Pennsylvania to Missouri?

Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $128). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MO?

It’s optimal to fly from Pennsylvania to Missouri in the evening. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Pennsylvania to Missouri?

Travelers seeking maximum savings on their Pennsylvania to Missouri flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Pennsylvania to Missouri

The most flights from USPA to USMO are scheduled on a Friday (10 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).

Reviews of airlines servicing Missouri

Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,092 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,052 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,080 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Pennsylvania to Missouri flight route?
Flights from Pennsylvania to Missouri have been viewed 39 times in the past calendar month.
How long is the flight from Pennsylvania to Missouri?
A quick flight from Pennsylvania to Missouri can take about 3h 02m. Spirit Airlines provides one of the quickest options available for as low as $241. There are 869 mi between Pennsylvania and Missouri. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Pennsylvania to Missouri one-way?
One-way options have recently been found by users for as low as $70 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $80 and American Airlines from $89 one-way.
Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?
Yes. In addition to deals on Pennsylvania to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Pennsylvania to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pennsylvania to Missouri.
Can I find deals for business class flights from Pennsylvania to Missouri?
Yes. Cheapflights offers flight deals from Pennsylvania to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Pennsylvania to Missouri?
Currently, February is the cheapest month in which you can book a flight from Pennsylvania to Missouri (average of $128). Flying from Pennsylvania to Missouri in June is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Pennsylvania to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$95	Average$303	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$130	Average$246	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$171	Average$406	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$219	Average$365	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$241	Average$408	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$248	Average$423	FlexibilityNo cancel fee	On-time69%

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$51+ Cheap flights from Pennsylvania to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Pennsylvania to Missouri with Cheapflights

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3. Compare prices and book

Cheap flight deals from Pennsylvania to Missouri

Cheapest flights from Pennsylvania to MissouriExplore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.

Find flight deals from Pennsylvania to Missouri

Keep the following information in mind while searching for Pennsylvania to Missouri flight deals. Data was last updated December 14, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Pennsylvania to Missouri that are best for you.

Best time to book a flight from Pennsylvania to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Pennsylvania with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Pennsylvania to Missouri

What is the cheapest month to book a flight from Pennsylvania to Missouri?

What is the cheapest time of day to fly from PA to MO?

Find hourly flight availability from Pennsylvania to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 14, 2025.

What is the cheapest day to fly from Pennsylvania to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Pennsylvania to Missouri. Price data was last updated on December 16, 2024.

Weekly flight availability from Pennsylvania to Missouri

Reviews of airlines servicing Missouri

Read through reviews of airlines operating flights from Pennsylvania to Missouri, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Pennsylvania to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Pennsylvania to Missouri flight route?

How long is the flight from Pennsylvania to Missouri?

What are the cheapest airlines to fly from Pennsylvania to Missouri one-way?

Can I find deals for flights from Pennsylvania to Missouri that include hotel bookings?

How can I find direct flights from Pennsylvania to Missouri?

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Cheapest flights from Pennsylvania to Missouri
Explore the most affordable flight options available from Pennsylvania to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 14, 2025.