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$313+ Cheap flights from Panama City (PTY) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$413
(American Airlines)

One-way from

$313
(Delta)

Popular in

September

Cheapest in

April

Average price

$478
Provider with most accurate pricing for Panama City Tocumen Intl-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Kansas City flights.
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From Panama City Tocumen Intl to Missouri
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One-way flight from Panama City Tocumen Intl to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/21:50 pmPTY - STL
2 stops22h 23mAmerican Airlines
Mon 7/75:14 pmSTL - PTY
2 stops19h 40mAmerican Airlines
Deal found 4/17$413
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/27:55 amPTY - STL
1 stop14h 20mUnited Airlines
Thu 6/58:25 amSTL - PTY
1 stop7h 47mUnited Airlines
Deal found 4/16$442
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/272:12 pmPTY - STL
1 stop9h 27mDelta
Fri 9/56:00 amSTL - PTY
1 stop6h 54mDelta
Deal found 4/17$463
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:14 pmPTY - MCI
1 stop9h 43mDelta
Mon 10/66:00 amMCI - PTY
1 stop6h 47mDelta
Deal found 4/16$518
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1410:00 amPTY - SGF
1 stop8h 15mUnited Airlines
Fri 5/166:15 amSGF - PTY
1 stop12h 22mUnited Airlines
Deal found 4/15$582
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/313:20 pmPTY - MCI
2 stops17h 44mUnited Airlines
Sat 6/72:56 pmMCI - PTY
1 stop23h 18mUnited Airlines
Deal found 4/16$582
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/141:20 pmPTY - SGF
2 stops19h 27mAmerican Airlines
Fri 5/164:09 pmSGF - PTY
2 stops20h 10mAmerican Airlines
Deal found 4/15$609
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/241:20 pmPTY - MCI
2 stops25h 41mAmerican Airlines
Sun 6/16:33 pmMCI - PTY
2 stops17h 46mAmerican Airlines
Deal found 4/16$610
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/13:20 amPTY - STL
2 stops20h 29mMultiple Airlines
Thu 6/510:10 amSTL - PTY
1 stop10h 09mMultiple Airlines
Deal found 4/16$621
This KAYAK deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/13:20 amPTY - STL
2 stops14h 40mAvianca
Thu 6/58:15 amSTL - PTY
2 stops15h 55mAvianca
Deal found 4/17$2,993

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 7/2

1:50 pm-12:13 pm

2 stops22h 23m

Lambert-St Louis

Mon 7/7

5:14 pm-12:54 pm

2 stops19h 40m

$413

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 6/2

7:55 am-10:15 pm

1 stop14h 20m

Lambert-St Louis

Thu 6/5

8:25 am-4:12 pm

1 stop7h 47m

$442

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Wed 8/27

2:12 pm-11:39 pm

1 stop9h 27m

Lambert-St Louis

Fri 9/5

6:00 am-12:54 pm

1 stop6h 54m

$463

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Wed 10/1

3:20 pm-9:09 am

2 stops17h 49m

Kansas City

Mon 10/6

6:32 pm-6:37 pm

2 stops24h 05m

$518

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Wed 5/14

10:00 am-6:15 pm

1 stop8h 15m

Springfield-Branson

Fri 5/16

6:15 am-6:37 pm

1 stop12h 22m

$582

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Wed 5/14

1:20 pm-8:47 am

2 stops19h 27m

Springfield-Branson

Fri 5/16

4:09 pm-12:19 pm

2 stops20h 10m

$609

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sat 5/24

1:20 pm-3:01 pm

2 stops25h 41m

Kansas City

Sun 6/1

6:33 pm-12:19 pm

2 stops17h 46m

$610

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 6/1

3:20 am-11:49 pm

2 stops20h 29m

Lambert-St Louis

Thu 6/5

10:10 am-8:19 pm

1 stop10h 09m

$621

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Sun 6/1

3:20 am-6:00 pm

2 stops14h 40m

Lambert-St Louis

Thu 6/5

8:15 am-12:10 am

2 stops15h 55m

$2,993

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Wed 9/3

2:12 pm-11:53 pm

1 stop9h 41m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 12 results
1
2

Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 17, 2025.
To help decide which airline to fly from Panama City to Missouri, see what other customers have to say about Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,916 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,667 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,316 reviews
Delta
8.0
Very good
7,916 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    For a flight from Panama City to Missouri, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • What are the cheapest airlines to fly from Panama City to Missouri one-way?

    $313 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $322 and $4,401, respectively.

  • What are the most popular routes from Panama City to Missouri?

    The most popular flight routes from Panama City to Missouri are Panama City Tocumen Intl - Lambert-St Louis, Panama City Tocumen Intl - Kansas City and Panama City Tocumen Intl - Springfield-Branson.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Missouri

Discover the top 2 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$252Average$563FlexibilityNo cancel feeOn-time69%
DeltaCheapest$354Average$558FlexibilityNo cancel feeOn-timeN/A

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