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$334+ Cheap flights from Panama City (PTY) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
Apr 5 — Apr 121
Sat 4/5
Sat 4/12
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$449
(United Airlines)

One-way from

$334
(Delta)

Popular in

September

Cheapest in

April

Average price

$554
Provider with most accurate pricing for Panama City Tocumen Intl-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Kansas City flights.
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From Panama City Tocumen Intl to Missouri
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One-way flight from Panama City Tocumen Intl to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/67:55 amPTY - STL
2 stops13h 53mUnited Airlines
Tue 5/136:30 amSTL - PTY
2 stops12h 07mUnited Airlines
Deal found 3/30$449
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/192:13 pmPTY - STL
1 stop9h 25mDelta
Sat 6/76:00 amSTL - PTY
1 stop6h 48mDelta
Deal found 3/30$493
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/191:20 pmPTY - STL
1 stop28h 09mAmerican Airlines
Sat 6/74:17 pmSTL - PTY
2 stops20h 43mAmerican Airlines
Deal found 3/30$506
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:55 amPTY - MCI
1 stop30h 15mUnited Airlines
Tue 4/86:45 pmMCI - PTY
2 stops21h 27mUnited Airlines
Deal found 3/30$511
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/301:20 pmPTY - MCI
2 stops21h 30mAmerican Airlines
Tue 7/15:45 pmMCI - PTY
2 stops19h 15mAmerican Airlines
Deal found 3/31$531
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:10 pmPTY - MCI
3 stops24h 02mMultiple Airlines
Sun 5/187:58 pmMCI - PTY
3 stops28h 12mMultiple Airlines
Deal found 3/31$669
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/89:50 amPTY - STL
3 stops33h 53mMultiple Airlines
Mon 5/125:15 pmSTL - PTY
3 stops30h 55mMultiple Airlines
Deal found 3/30$994
This Avianca deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/53:25 amPTY - STL
2 stops13h 58mAvianca
Tue 5/139:40 amSTL - PTY
2 stops14h 30mAvianca
Deal found 3/30$2,957

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 5/6

7:55 am-9:48 pm

2 stops13h 53m

Lambert-St Louis

Tue 5/13

6:30 am-6:37 pm

2 stops12h 07m

$449

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/19

2:13 pm-11:38 pm

1 stop9h 25m

Lambert-St Louis

Sat 6/7

6:00 am-12:48 pm

1 stop6h 48m

$493

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/19

1:20 pm-5:29 pm

1 stop28h 09m

Lambert-St Louis

Sat 6/7

4:17 pm-1:00 pm

2 stops20h 43m

$506

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sun 4/20

10:00 am-6:55 pm

1 stop8h 55m

Kansas City

Fri 4/25

6:45 pm-2:14 pm

2 stops19h 29m

$518

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Fri 5/30

1:20 pm-10:50 am

2 stops21h 30m

Kansas City

Tue 7/1

5:45 pm-1:00 pm

2 stops19h 15m

$531

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Thu 5/15

8:10 pm-8:12 pm

3 stops24h 02m

Kansas City

Sun 5/18

7:58 pm-12:10 am

3 stops28h 12m

$669

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 5/8

9:50 am-7:43 pm

3 stops33h 53m

Lambert-St Louis

Mon 5/12

5:15 pm-12:10 am

3 stops30h 55m

$994

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/5

3:25 am-5:23 pm

2 stops13h 58m

Lambert-St Louis

Tue 5/13

9:40 am-12:10 am

2 stops14h 30m

$2,957

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sun 6/15

8:10 am-4:23 pm

1 stop8h 13m

$334

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sun 6/15

3:20 pm-9:56 am

2 stops18h 36m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 11 results
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Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 31, 2025.
To help decide which airline to fly from Panama City to Missouri, see what other customers have to say about Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,614 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,301 reviews
Delta
8.0
Very good
7,899 reviews

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    For a flight from Panama City to Missouri, you will be flying from Tocumen Intl. Panama City Tocumen Intl (PTY) is just 11.4 mi from the center of the city.

  • What are the most popular routes from Panama City to Missouri?

    The most popular flight routes from Panama City to Missouri are Panama City Tocumen Intl - Lambert-St Louis, Panama City Tocumen Intl - Kansas City and Panama City Tocumen Intl - Springfield-Branson.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Missouri (average of $311). Flying from Panama City to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Missouri

Discover the top 2 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$354Average$602FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$420Average$616FlexibilityNo cancel feeOn-time69%
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