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Missouri

$273+ Cheap flights from Panama to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
abr. 27 — may. 41
dom. 4/27
dom. 5/4
1 adult, Economy
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Cheap flight deals from Panama to Missouri

Keep the following information in mind while searching for Panama to Missouri flight deals. Data was last updated abril 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$416
(Delta)

One-way from

$273
(Kiwi.com)

Popular in

September

Cheapest in

April

Average price

$478
Provider with most accurate pricing for Panama City Tocumen Intl-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Kansas City flights.
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From Panama to Missouri
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One-way flight from Panama to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama to Missouri

Cheapest flights from Panama to Missouri
Explore the most affordable flight options available from Panama to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 22, 2025.

This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/12:23 pmPTY - MCI
1 stop9h 45mDelta
vie. 8/18:00 amMCI - PTY
1 stop11h 08mDelta
Deal found 4/21$416
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/21:20 pmPTY - STL
2 stops23h 47mAmerican Airlines
jue. 6/54:37 pmSTL - PTY
2 stops21h 48mAmerican Airlines
Deal found 4/22$422
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/11:50 pmPTY - MCI
2 stops20h 25mAmerican Airlines
vie. 8/17:20 pmMCI - PTY
2 stops18h 55mAmerican Airlines
Deal found 4/21$429
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/23:20 pmPTY - STL
1 stop19h 19mUnited Airlines
jue. 6/55:55 pmSTL - PTY
1 stop22h 17mUnited Airlines
Deal found 4/22$433
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/13:20 pmPTY - MCI
1 stop22h 58mUnited Airlines
vie. 8/16:27 pmMCI - PTY
2 stops19h 47mUnited Airlines
Deal found 4/21$443
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/272:12 pmPTY - STL
1 stop9h 27mDelta
vie. 9/56:00 amSTL - PTY
1 stop6h 54mDelta
Deal found 4/21$474
This Avianca Connect deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/73:20 amPTY - MCI
2 stops19h 21mMultiple Airlines
vie. 5/165:46 amMCI - PTY
2 stops18h 24mMultiple Airlines
Deal found 4/21$622
This Mytrip deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/73:20 amPTY - STL
3 stops32h 50mMultiple Airlines
lun. 5/122:30 pmSTL - PTY
3 stops33h 40mMultiple Airlines
Deal found 4/21$1,002
This KAYAK deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/2410:05 pmPTY - STL
2 stops35h 53mAvianca
lun. 4/288:25 amSTL - PTY
3 stops28h 10mAvianca
Deal found 4/21$1,943

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
Use the filters below to find and compare flights from Panama to Missouri that are best for you.

Fly from

Panama

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mar. 7/1

2:23 pm-12:08 am

1 stop9h 45m

Kansas City

vie. 8/1

8:00 am-7:08 pm

1 stop11h 08m

$416

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

lun. 6/2

1:20 pm-1:07 pm

2 stops23h 47m

Lambert-St Louis

jue. 6/5

4:37 pm-2:25 pm

2 stops21h 48m

$422

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mar. 7/1

1:50 pm-10:15 am

2 stops20h 25m

Kansas City

vie. 8/1

7:20 pm-2:15 pm

2 stops18h 55m

$429

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

lun. 6/2

3:20 pm-10:39 am

1 stop19h 19m

Lambert-St Louis

jue. 6/5

5:55 pm-4:12 pm

1 stop22h 17m

$433

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mar. 7/1

3:20 pm-2:18 pm

1 stop22h 58m

Kansas City

vie. 8/1

6:27 pm-2:14 pm

2 stops19h 47m

$443

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 8/27

2:12 pm-11:39 pm

1 stop9h 27m

Lambert-St Louis

vie. 9/5

6:00 am-12:54 pm

1 stop6h 54m

$474

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

mié. 5/7

3:20 am-10:41 pm

2 stops19h 21m

Kansas City

vie. 5/16

5:46 am-12:10 am

2 stops18h 24m

$622

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

mié. 5/7

3:20 am-12:10 pm

3 stops32h 50m

Lambert-St Louis

lun. 5/12

2:30 pm-12:10 am

3 stops33h 40m

$1,002

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

dom. 6/1

3:20 am-9:56 am

2 stops30h 36m

Lambert-St Louis

jue. 6/5

8:15 am-12:10 am

2 stops15h 55m

$2,411

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

jue. 5/15

9:21 pm-10:31 am

2 stops13h 10m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/21

Showing 1-10 of 17 results
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Best time to book a flight from Panama to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Missouri

What is the cheapest month to book a flight from Panama to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MO?

Find hourly flight availability from Panama to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 22, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated abril 22, 2025.
Read through reviews of airlines operating flights from Panama to Missouri, such as Delta, United Airlines and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,683 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,319 reviews
Delta
8.0
Very good
7,920 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Panama to Missouri one-way?

    One-way options have recently been found by users for as low as $292 on Delta. Other airlines that offer cheap prices include United Airlines from $359 and American Airlines from $377 one-way.

  • Can I find deals for flights from Panama to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Missouri.

  • Can I find deals for business class flights from Panama to Missouri?

    Yes. Cheapflights offers flight deals from Panama to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Missouri

Discover the top 2 airlines that operate flights from Panama to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$252Average$554FlexibilityNo cancel feeOn-time69%
DeltaCheapest$354Average$558FlexibilityNo cancel feeOn-timeN/A

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