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Missouri

$296+ Cheap flights from Panama to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — STL
Apr 7 — Apr 141
Mon 4/7
Mon 4/14
1 adult, Economy
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Cheap flight deals from Panama to Missouri

Keep the following information in mind while searching for Panama to Missouri flight deals. Data was last updated April 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$449
(Delta)

One-way from

$296
(Delta)

Popular in

September

Cheapest in

April

Average price

$478
Provider with most accurate pricing for Panama City Tocumen Intl-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Kansas City flights.
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From Panama to Missouri
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One-way flight from Panama to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama to Missouri

Cheapest flights from Panama to Missouri
Explore the most affordable flight options available from Panama to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2025.

This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/62:20 pmPTY - STL
1 stop9h 16mDelta
Tue 5/136:00 amSTL - PTY
1 stop6h 48mDelta
Deal found 4/1$449
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1910:00 amPTY - STL
1 stop29h 49mUnited Airlines
Sat 6/75:27 pmSTL - PTY
2 stops20h 47mUnited Airlines
Deal found 3/31$493
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/191:20 pmPTY - STL
1 stop28h 09mAmerican Airlines
Sat 6/78:05 pmSTL - PTY
2 stops18h 20mAmerican Airlines
Deal found 4/1$506
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/37:55 amPTY - MCI
1 stop14h 31mUnited Airlines
Tue 4/86:20 amMCI - PTY
1 stop12h 17mUnited Airlines
Deal found 4/1$511
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/12:14 pmPTY - MCI
1 stop9h 43mDelta
Mon 10/66:00 amMCI - PTY
1 stop6h 47mDelta
Deal found 4/1$518
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/161:20 pmPTY - SGF
2 stops19h 27mAmerican Airlines
Fri 5/237:17 pmSGF - PTY
2 stops17h 02mAmerican Airlines
Deal found 4/1$606
This United Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/163:20 pmPTY - SGF
2 stops23h 25mUnited Airlines
Fri 5/238:35 amSGF - PTY
1 stop7h 37mUnited Airlines
Deal found 4/1$691
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/162:13 pmPTY - SGF
1 stop8h 04mDelta
Fri 5/2312:00 pmSGF - PTY
1 stop7h 53mDelta
Deal found 4/1$706
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/61:50 pmPTY - MCI
2 stops18h 44mAmerican Airlines
Sat 9/136:35 pmMCI - PTY
2 stops17h 50mAmerican Airlines
Deal found 4/1$1,469
This Expedia deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/243:20 amPTY - STL
2 stops35h 56mMultiple Airlines
Tue 7/2910:00 amSTL - PTY
2 stops24h 25mMultiple Airlines
Deal found 4/1$1,694
This Avianca deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/53:25 amPTY - STL
2 stops13h 58mAvianca
Tue 5/138:25 amSTL - PTY
2 stops15h 45mAvianca
Deal found 4/1$3,228

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
Use the filters below to find and compare flights from Panama to Missouri that are best for you.

Fly from

Panama

Fly to

Missouri

Route

Depart

Return

Price

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Tue 5/6

2:20 pm-11:36 pm

1 stop9h 16m

Lambert-St Louis

Tue 5/13

6:00 am-12:48 pm

1 stop6h 48m

$449

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/19

10:00 am-3:49 pm

1 stop29h 49m

Lambert-St Louis

Sat 6/7

5:27 pm-2:14 pm

2 stops20h 47m

$493

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/19

1:20 pm-5:29 pm

1 stop28h 09m

Lambert-St Louis

Sat 6/7

8:05 pm-2:25 pm

2 stops18h 20m

$506

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sun 4/20

10:00 am-6:55 pm

1 stop8h 55m

Kansas City

Fri 4/25

6:20 am-4:12 pm

1 stop9h 52m

$518

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Fri 5/16

1:20 pm-8:47 am

2 stops19h 27m

Springfield-Branson

Fri 5/23

7:17 pm-12:19 pm

2 stops17h 02m

$606

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Fri 5/16

3:20 pm-2:45 pm

2 stops23h 25m

Springfield-Branson

Fri 5/23

8:35 am-4:12 pm

1 stop7h 37m

$691

Panama CitySpringfield

PTY - SGF

PTYSGF

Panama City Tocumen Intl

Fri 5/16

2:13 pm-10:17 pm

1 stop8h 04m

Springfield-Branson

Fri 5/23

12:00 pm-7:53 pm

1 stop7h 53m

$706

Panama CityKansas City

PTY - MCI

PTYMCI

Panama City Tocumen Intl

Sat 9/6

1:50 pm-8:34 am

2 stops18h 44m

Kansas City

Sat 9/13

6:35 pm-12:25 pm

2 stops17h 50m

$1,469

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Thu 7/24

3:20 am-3:16 pm

2 stops35h 56m

Lambert-St Louis

Tue 7/29

10:00 am-10:25 am

2 stops24h 25m

$1,694

Panama CitySt. Louis

PTY - STL

PTYSTL

Panama City Tocumen Intl

Mon 5/5

3:25 am-5:23 pm

2 stops13h 58m

Lambert-St Louis

Tue 5/13

8:25 am-12:10 am

2 stops15h 45m

$3,228

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 13 results
1
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Best time to book a flight from Panama to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Missouri

What is the cheapest month to book a flight from Panama to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MO?

Find hourly flight availability from Panama to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 2, 2025.
Read through reviews of airlines operating flights from Panama to Missouri, such as Delta, United Airlines and American Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,899 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,615 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Avianca
6.7
Okay
2,301 reviews
Delta
8.0
Very good
7,899 reviews

Boarding

8.2

Comfort

8.0

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Panama to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Missouri.

  • Can I find deals for business class flights from Panama to Missouri?

    Yes. Cheapflights offers flight deals from Panama to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama to Missouri (average of $311). Flying from Panama to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Missouri

Discover the top 2 airlines that operate flights from Panama to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$354Average$602FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$420Average$616FlexibilityNo cancel feeOn-time69%

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