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$109+ Cheap flights from Panama City, FL (ECP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/18. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — STL
Feb 26 — Mar 51
Wed 2/26
Wed 3/5
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated February 21, 2025.

Round-trip from

$237
(Delta)

One-way from

$109
(Delta)

Good round-trip deal

$373 or less

Good one-way deal

$234 or less
From Panama City NW Florida Beaches to Missouri
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One-way flight from Panama City NW Florida Beaches to Missouri
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Missouri.
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Missouri.
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:34 pmECP - MCI
1 stop6h 11mDelta
Tue 3/112:27 pmMCI - ECP
1 stop3h 39mDelta
Deal found 2/20$237
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/73:38 pmECP - MCI
1 stop7h 24mAmerican Airlines
Tue 3/117:00 amMCI - ECP
2 stops8h 53mAmerican Airlines
Deal found 2/20$242
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:00 amECP - SGF
1 stop5h 23mDelta
Mon 5/53:30 pmSGF - ECP
1 stop4h 10mDelta
Deal found 2/19$249
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/302:27 pmECP - SGF
2 stops9h 21mAmerican Airlines
Sat 5/34:26 pmSGF - ECP
1 stop4h 11mAmerican Airlines
Deal found 2/19$254
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/610:10 amECP - STL
Nonstop1h 55mSouthwest
Tue 4/112:20 pmSTL - ECP
Nonstop1h 45mSouthwest
Deal found 2/21$313
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/107:25 amECP - MCI
1 stop4h 00mSouthwest
Sun 4/133:05 pmMCI - ECP
Nonstop2h 00mSouthwest
Deal found 2/20$327
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/35:01 pmECP - SGF
1 stop5h 14mUnited Airlines
Sun 5/48:50 amSGF - ECP
1 stop7h 29mUnited Airlines
Deal found 2/19$355
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/262:41 pmECP - STL
2 stops7h 37mAmerican Airlines
Fri 3/285:55 amSTL - ECP
2 stops6h 37mAmerican Airlines
Deal found 2/20$361
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/203:09 pmECP - STL
1 stop5h 27mUnited Airlines
Sun 5/258:10 amSTL - ECP
1 stop4h 56mUnited Airlines
Deal found 2/19$440
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/166:51 pmECP - STL
1 stop4h 40mDelta
Tue 3/186:00 amSTL - ECP
1 stop4h 17mDelta
Deal found 2/20$481

Find flights from Panama City to Missouri within your budget

Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Fri 3/7

5:34 pm-11:45 pm

1 stop6h 11m

Kansas City

Tue 3/11

2:27 pm-6:06 pm

1 stop3h 39m

$237

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Fri 3/7

3:38 pm-11:02 pm

1 stop7h 24m

Kansas City

Tue 3/11

7:00 am-3:53 pm

2 stops8h 53m

$242

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

Wed 4/30

6:00 am-11:23 am

1 stop5h 23m

Springfield-Branson

Mon 5/5

3:30 pm-7:40 pm

1 stop4h 10m

$249

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

Wed 4/30

2:27 pm-11:48 pm

2 stops9h 21m

Springfield-Branson

Sat 5/3

4:26 pm-8:37 pm

1 stop4h 11m

$254

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Thu 3/6

10:10 am-12:05 pm

Nonstop1h 55m

Lambert-St Louis

Tue 4/1

12:20 pm-2:05 pm

Nonstop1h 45m

$313

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Thu 4/10

7:25 am-11:25 am

1 stop4h 00m

Kansas City

Sun 4/13

3:05 pm-5:05 pm

Nonstop2h 00m

$327

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

Sat 5/3

5:01 pm-10:15 pm

1 stop5h 14m

Springfield-Branson

Sun 5/4

8:50 am-4:19 pm

1 stop7h 29m

$355

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Wed 3/26

2:41 pm-10:18 pm

2 stops7h 37m

Lambert-St Louis

Fri 3/28

5:55 am-12:32 pm

2 stops6h 37m

$361

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Tue 5/20

3:09 pm-8:36 pm

1 stop5h 27m

Lambert-St Louis

Sun 5/25

8:10 am-1:06 pm

1 stop4h 56m

$440

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Sun 3/16

6:51 pm-11:31 pm

1 stop4h 40m

Lambert-St Louis

Tue 3/18

6:00 am-10:17 am

1 stop4h 17m

$481

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 18 results
1
2

Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Missouri

Get recent, data-driven insights about flights from Panama City to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City, Florida to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 21, 2025.
Read through reviews of airlines operating flights from Panama City to Missouri, such as Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,401 reviews

Comfort

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,401 reviews
Southwest
8.1
Very good
4,401 reviews

Comfort

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,213 reviews
Southwest
8.1
Very good
4,401 reviews

Comfort

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,759 reviews
Southwest
8.1
Very good
4,401 reviews

Comfort

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,401 reviews

Comfort

8.1

Entertainment

7.6

Food

7.1

Crew

8.7

Overall

8.1

Boarding

8.2

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    If you book a flight to Missouri from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to Missouri one-way?

    One-way options have recently been found by users for as low as $109 on Delta. Other airlines that offer cheap prices include Southwest from $114 and United Airlines from $149 one-way.

  • What are the most popular routes from Panama City, Florida to Missouri?

    Most travelers choose Panama City NW Florida Beaches - Lambert-St Louis, Panama City NW Florida Beaches - Kansas City or Panama City NW Florida Beaches - Springfield-Branson when deciding on the best route from Panama City, Florida to Missouri.

  • What are the cheapest flights from Panama City, Florida to Missouri?

    The cheapest flight price from Panama City, Florida to Missouri is $156. On average you can expect to pay $335. The most popular route, (Panama City NW Florida Beaches - Lambert-St Louis), can usually be booked for $331.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Missouri

Discover the top 4 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$391FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$258Average$346FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$266Average$432FlexibilityNo cancel feeOn-time63%
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