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$114+ Cheap flights from Panama City, FL (ECP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — STL
Mar 30 — Apr 61
Sun 3/30
Sun 4/6
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated March 25, 2025.

Round-trip from

$237
(Delta)

One-way from

$114
(American Airlines)

Good round-trip deal

$353 or less

Good one-way deal

$208 or less
From Panama City NW Florida Beaches to Missouri
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One-way flight from Panama City NW Florida Beaches to Missouri
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Missouri.
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Missouri.
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:47 amECP - MCI
1 stop5h 11mAmerican Airlines
Wed 6/412:28 pmMCI - ECP
1 stop6h 23mAmerican Airlines
Deal found 3/24$245
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/86:40 amECP - SGF
1 stop7h 07mAmerican Airlines
Tue 4/159:10 amSGF - ECP
1 stop5h 41mAmerican Airlines
Deal found 3/22$254
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/169:12 amECP - STL
1 stop5h 23mDelta
Mon 5/191:09 pmSTL - ECP
1 stop4h 55mDelta
Deal found 3/23$297
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/164:29 pmECP - STL
1 stop4h 57mAmerican Airlines
Mon 5/196:00 amSTL - ECP
2 stops7h 49mAmerican Airlines
Deal found 3/23$329
This Delta deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:15 amECP - MCI
1 stop4h 55mDelta
Sun 5/117:00 amMCI - ECP
1 stop6h 04mDelta
Deal found 3/25$331
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/126:05 pmECP - MCI
1 stop3h 45mSouthwest
Sat 4/193:45 pmMCI - ECP
Nonstop2h 00mSouthwest
Deal found 3/24$385
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/113:15 pmECP - STL
1 stop4h 15mSouthwest
Tue 7/157:50 pmSTL - ECP
Nonstop1h 45mSouthwest
Deal found 3/23$405
This United deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/56:30 amECP - STL
3 stops33h 17mUnited Airlines
Mon 5/128:30 amSTL - ECP
1 stop6h 09mUnited Airlines
Deal found 3/23$514
This United deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:00 pmECP - MCI
1 stop5h 39mUnited Airlines
Sun 5/113:10 pmMCI - ECP
3 stops22h 03mUnited Airlines
Deal found 3/25$525

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Wed 5/28

6:47 am-11:58 am

1 stop5h 11m

Kansas City

Wed 6/4

12:28 pm-6:51 pm

1 stop6h 23m

$245

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

Tue 4/8

6:40 am-1:47 pm

1 stop7h 07m

Springfield-Branson

Tue 4/15

9:10 am-2:51 pm

1 stop5h 41m

$254

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 5/16

9:12 am-2:35 pm

1 stop5h 23m

Lambert-St Louis

Mon 5/19

1:09 pm-6:04 pm

1 stop4h 55m

$297

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 5/16

4:29 pm-9:26 pm

1 stop4h 57m

Lambert-St Louis

Mon 5/19

6:00 am-1:49 pm

2 stops7h 49m

$329

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Thu 5/8

7:15 am-12:10 pm

1 stop4h 55m

Kansas City

Sun 5/11

7:00 am-1:04 pm

1 stop6h 04m

$331

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Sat 4/12

6:05 pm-9:50 pm

1 stop3h 45m

Kansas City

Sat 4/19

3:45 pm-5:45 pm

Nonstop2h 00m

$385

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Fri 7/11

3:15 pm-7:30 pm

1 stop4h 15m

Lambert-St Louis

Tue 7/15

7:50 pm-9:35 pm

Nonstop1h 45m

$405

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Mon 5/5

6:30 am-3:47 pm

3 stops33h 17m

Lambert-St Louis

Mon 5/12

8:30 am-2:39 pm

1 stop6h 09m

$514

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

Thu 5/8

1:00 pm-6:39 pm

1 stop5h 39m

Kansas City

Sun 5/11

3:10 pm-1:13 pm

3 stops22h 03m

$525

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

Wed 4/30

2:27 pm-9:24 pm

1 stop6h 57m

$114

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 17 results
1
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Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City, Florida to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 25, 2025.
Read through reviews of airlines operating flights from Panama City to Missouri, such as Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,272 reviews

Crew

8.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,272 reviews
Southwest
8.0
Very good
4,272 reviews

Crew

8.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,890 reviews
Southwest
8.0
Very good
4,272 reviews

Crew

8.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,605 reviews
Southwest
8.0
Very good
4,272 reviews

Crew

8.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,272 reviews

Crew

8.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    If you book a flight to Missouri from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to Missouri one-way?

    One-way options have recently been found by users for as low as $114 on American Airlines. Other airlines that offer cheap prices include Delta from $119 and United Airlines from $128 one-way.

  • What are the most popular routes from Panama City, Florida to Missouri?

    Most travelers choose Panama City NW Florida Beaches - Lambert-St Louis, Panama City NW Florida Beaches - Kansas City or Panama City NW Florida Beaches - Springfield-Branson when deciding on the best route from Panama City, Florida to Missouri.

  • What are the cheapest flights from Panama City, Florida to Missouri?

    The cheapest flight price from Panama City, Florida to Missouri is $119. On average you can expect to pay $331. The most popular route, (Panama City NW Florida Beaches - Lambert-St Louis), can usually be booked for $297.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Panama City to Missouri

Discover the top 4 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$378FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$242Average$441FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$258Average$353FlexibilityNo cancel feeOn-time69%
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