What are the cheapest airlines to fly from Maine to Missouri one-way?

To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $114. Allegiant Air flights start at $143 while deals on Spirit Airlines start at $145 one-way.

How far in advance should I book a flight from Maine to Missouri?

Travelers have found it’s best to book a flight 44 days in advance to save up to 135% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 44 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from Maine to Missouri 1-2 weeks in advance for as low as $583, or $745 for flights within the next 24 hours.

What is the cheapest month to fly from Maine to Missouri?

Due to multiple factors, expect to potentially pay more when booking in April. For low rates, January can be a great choice for travel to Missouri. Flights to Missouri from Maine in January are about $466 on average during January, but can be found for as low as $348.

Can I find deals for flights from Maine to Missouri that include hotel bookings?

Yes. In addition to deals on Maine to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Maine to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Missouri.

Can I find deals for business class flights from Maine to Missouri?

Yes. Cheapflights offers flight deals from Maine to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$114+ Flights from Maine to Missouri

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Cheap flight deals from Maine to Missouri

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$208 (Booking.com)
One-way from	$114 (Expedia)
Popular in	April
Cheapest in	January
Average price	$780

Provider with most accurate pricing for Portland-Kansas City flight deals.

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Provider most trusted by Cheapflights users for Portland-Kansas City flights.

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From Maine to Missouri

Search Deals

One-way flight from Maine to Missouri

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($65 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($29 potential savings vs. average RT price).

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Average for round-trip flights in April 2025

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Find flight deals from Maine to Missouri

Cheapest flights from Maine to Missouri
Explore the most affordable flight options available from Maine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Mon 5/129:30 pmPWM - STL

1 stop27h 36mFrontier

Thu 5/155:45 pmSTL - PWM

1 stop25h 55mFrontier

Deal found 3/31

$208

Wed 10/154:59 pmBGR - STL

1 stop7h 30mAmerican Airlines

Sat 10/189:36 amSTL - BGR

1 stop4h 47mAmerican Airlines

Deal found 3/31

$259

Sat 4/261:47 pmBOS - SGF

1 stop9h 32mAmerican Airlines

Fri 5/3012:25 pmSGF - BOS

1 stop10h 19mAmerican Airlines

Deal found 3/30

$275

Wed 5/214:01 pmPWM - STL

1 stop5h 57mAmerican Airlines

Wed 5/284:01 pmSTL - PWM

1 stop6h 54mAmerican Airlines

Deal found 3/31

$285

Mon 4/285:06 amBOS - MCI

1 stop11h 20mSpirit Airlines

Wed 4/303:59 pmMCI - BOS

1 stop16h 31mSpirit Airlines

Deal found 3/31

$285

Wed 5/216:05 amPWM - STL

2 stops9h 30mDelta

Wed 5/286:00 amSTL - PWM

1 stop5h 57mDelta

Deal found 3/31

$290

Tue 5/135:30 amPWM - MCI

1 stop7h 40mDelta

Tue 5/205:26 pmMCI - PWM

1 stop5h 33mDelta

Deal found 3/31

$299

Wed 5/215:45 amBOS - MCI

1 stop9h 05mMultiple Airlines

Sun 5/2510:15 amMCI - BOS

2 stops24h 45mMultiple Airlines

Deal found 3/31

$300

Fri 9/54:57 pmBOS - MCI

1 stop7h 31mUnited Airlines

Sat 9/67:30 amMCI - BOS

1 stop5h 36mUnited Airlines

Deal found 3/31

$314

Sat 5/35:38 amPWM - MCI

1 stop7h 17mAmerican Airlines

Tue 5/61:48 pmMCI - PWM

1 stop7h 57mAmerican Airlines

Deal found 3/31

$318

Wed 4/99:55 amBOS - STL

3 stops33h 46mMultiple Airlines

Mon 4/149:50 amSTL - BOS

3 stops25h 46mMultiple Airlines

Deal found 3/30

$319

Sat 5/39:30 amBOS - MCI

Nonstop3h 43mDelta

Sat 5/1011:55 amMCI - BOS

Nonstop3h 09mDelta

Deal found 4/1

$319

Best flights from Maine to Missouri
Discover carefully curated flight deals from Maine to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2025.

Mon 5/129:30 pmPWM - STL

1 stop27h 36mFrontier

Thu 5/155:45 pmSTL - PWM

1 stop25h 55mFrontier

Deal found 3/31

$208

Sat 4/261:47 pmBOS - SGF

1 stop9h 32mAmerican Airlines

Fri 5/3012:25 pmSGF - BOS

1 stop10h 19mAmerican Airlines

Deal found 3/30

$275

Mon 4/285:06 amBOS - MCI

1 stop11h 20mSpirit Airlines

Wed 4/303:59 pmMCI - BOS

1 stop16h 31mSpirit Airlines

Deal found 3/31

$285

Wed 5/216:05 amPWM - STL

2 stops9h 30mDelta

Wed 5/286:00 amSTL - PWM

1 stop5h 57mDelta

Deal found 3/31

$290

Wed 5/215:45 amBOS - MCI

1 stop9h 05mMultiple Airlines

Sun 5/2510:15 amMCI - BOS

2 stops24h 45mMultiple Airlines

Deal found 3/31

$300

Fri 9/54:57 pmBOS - MCI

1 stop7h 31mUnited Airlines

Sat 9/67:30 amMCI - BOS

1 stop5h 36mUnited Airlines

Deal found 3/31

$314

Tue 5/207:05 amBOS - STL

Nonstop2h 55mSouthwest

Sat 5/246:45 pmSTL - BOS

Nonstop2h 30mSouthwest

Deal found 3/31

$327

Thu 5/111:39 amBOS - STL

1 stop24h 52mSun Country Air

Sun 5/48:00 amSTL - BOS

1 stop14h 04mSun Country Air

Deal found 3/30

$370

Thu 6/2611:24 amBGR - MCI

1 stop8h 47mAllegiant Air

Thu 7/37:59 pmMCI - BGR

1 stop21h 34mAllegiant Air

Deal found 3/31

$404

Thu 5/15:20 pmBOS - STL

1 stop31h 39mAlaska Airlines

Tue 5/66:30 amSTL - BOS

1 stop16h 29mAlaska Airlines

Deal found 3/31

$503

Wed 5/214:01 pmPWM - STL

1 stop5h 57mAmerican Airlines

Wed 5/284:01 pmSTL - PWM

1 stop6h 54mAmerican Airlines

Deal found 3/31

$285

Tue 5/135:30 amPWM - MCI

1 stop7h 40mDelta

Tue 5/205:26 pmMCI - PWM

1 stop5h 33mDelta

Deal found 3/31

$299

Last-minute flights from Maine to Missouri
Discover last-minute flight deals from Maine to Missouri. Data last updated April 1, 2025 and is based on user searches.

Wed 4/26:00 amBOS - STL

1 stop18h 46mFrontier

Sun 4/64:57 pmSTL - BOS

1 stop6h 50mFrontier

Deal found 4/1

$338

Tue 4/812:20 pmBOS - MCI

1 stop7h 24mAmerican Airlines

Tue 4/157:15 amMCI - BOS

1 stop8h 20mAmerican Airlines

Deal found 3/31

$461

Tue 4/811:14 amBOS - STL

1 stop7h 38mSpirit Airlines

Thu 4/246:10 pmSTL - BOS

1 stop15h 17mSpirit Airlines

Deal found 3/31

$493

Tue 4/83:00 pmBOS - MCI

2 stops8h 50mSouthwest

Tue 4/154:45 pmMCI - BOS

1 stop4h 40mSouthwest

Deal found 3/31

$549

Wed 4/99:55 amBOS - STL

3 stops33h 46mMultiple Airlines

Mon 4/149:50 amSTL - BOS

3 stops25h 46mMultiple Airlines

Deal found 3/30

$319

Wed 4/94:20 pmBOS - SGF

1 stop28h 18mMultiple Airlines

Sun 4/138:23 pmSGF - BOS

3 stops36h 07mMultiple Airlines

Deal found 3/31

$365

Wed 4/912:39 pmBGR - STL

1 stop5h 42mAmerican Airlines

Sun 4/136:13 amSTL - BGR

1 stop4h 53mAmerican Airlines

Deal found 3/31

$414

Wed 4/96:10 amBOS - SGF

1 stop10h 24mAmerican Airlines

Sun 4/135:25 amSGF - BOS

1 stop10h 17mAmerican Airlines

Deal found 3/31

$490

Wed 4/96:30 amBOS - STL

Nonstop3h 12mAmerican Airlines

Sun 4/136:13 amSTL - BOS

1 stop4h 00mAmerican Airlines

Deal found 4/1

$497

Thu 4/107:48 pmBOS - MCI

2 stops20h 38mMultiple Airlines

Sun 4/139:50 amMCI - BOS

2 stops31h 53mMultiple Airlines

Deal found 3/31

$366

Thu 4/106:25 amBOS - MCI

Nonstop3h 50mDelta

Mon 4/212:59 pmMCI - BOS

1 stop6h 32mDelta

Deal found 4/1

$529

Thu 4/109:30 amBOS - MCI

2 stops12h 09mUnited Airlines

Sun 4/1310:05 amMCI - BOS

1 stop25h 43mUnited Airlines

Deal found 3/30

$561

One-way flights from Maine to Missouri
Search for one-way flight options from Maine to Missouri. Find affordable one-way fares based on user searches. Data last updated April 1, 2025.

Tue 4/153:05 pmPWM - STL

1 stop9h 41mFrontier

Deal found 3/31

$114

Sat 5/2412:51 pmBOS - MCI

1 stop8h 36mAllegiant Air

Deal found 3/31

$143

Wed 6/186:10 amBOS - MCI

2 stops37h 15mSpirit Airlines

Deal found 3/31

$145

Thu 5/296:00 amBOS - STL

1 stop7h 20mUnited Airlines

Deal found 3/31

$147

Wed 5/73:49 pmBOS - STL

3 stops29h 21mMultiple Airlines

Deal found 3/31

$148

Tue 5/65:00 amBOS - MCI

1 stop9h 10mSouthwest

Deal found 4/1

$151

Tue 6/37:05 amBOS - STL

Nonstop2h 55mSouthwest

Deal found 3/31

$152

Sun 5/48:30 amBOS - MCI

1 stop12h 00mSun Country Air

Deal found 3/31

$153

Sat 6/147:59 pmBOS - STL

2 stops20h 23mSpirit Airlines

Deal found 3/31

$154

Wed 6/259:40 amBOS - STL

1 stop15h 09mFrontier

Deal found 3/31

$157

Sat 5/310:54 pmBOS - MCI

2 stops19h 30mMultiple Airlines

Deal found 4/1

$157

Thu 5/227:49 amBOS - MCI

1 stop8h 12mAmerican Airlines

Deal found 4/1

$160

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Mon 5/12

9:30 pm-12:06 am

1 stop27h 36m

Lambert-St Louis

Thu 5/15

5:45 pm-8:40 pm

1 stop25h 55m

$208

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

Sat 4/26

1:47 pm-10:19 pm

1 stop9h 32m

Springfield-Branson

Fri 5/30

12:25 pm-11:44 pm

1 stop10h 19m

$275

BostonKansas City

BOS - MCI

BOSMCI

Boston Logan Intl

Mon 4/28

5:06 am-3:26 pm

1 stop11h 20m

Kansas City

Wed 4/30

3:59 pm-9:30 am

1 stop16h 31m

$285

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/21

4:01 pm-8:58 pm

1 stop5h 57m

Lambert-St Louis

Wed 5/28

4:01 pm-11:55 pm

1 stop6h 54m

$285

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 5/21

6:05 am-2:35 pm

2 stops9h 30m

Lambert-St Louis

Wed 5/28

6:00 am-12:57 pm

1 stop5h 57m

$290

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Tue 5/13

5:30 am-12:10 pm

1 stop7h 40m

Kansas City

Tue 5/20

5:26 pm-11:59 pm

1 stop5h 33m

$299

BostonKansas City

BOS - MCI

BOSMCI

Boston Logan Intl

Wed 5/21

5:45 am-1:50 pm

1 stop9h 05m

Kansas City

Sun 5/25

10:15 am-12:00 pm

2 stops24h 45m

$300

BostonKansas City

BOS - MCI

BOSMCI

Boston Logan Intl

Fri 9/5

4:57 pm-11:28 pm

1 stop7h 31m

Kansas City

Sat 9/6

7:30 am-2:06 pm

1 stop5h 36m

$314

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Sat 5/3

5:38 am-11:55 am

1 stop7h 17m

Kansas City

Tue 5/6

1:48 pm-10:45 pm

1 stop7h 57m

$318

BostonKansas City

BOS - MCI

BOSMCI

Boston Logan Intl

Sat 5/3

9:30 am-12:13 pm

Nonstop3h 43m

Kansas City

Sat 5/10

11:55 am-4:04 pm

Nonstop3h 09m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 60 results

...

Best time to book a flight from Maine to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Maine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to Missouri

What is the cheapest month to book a flight from Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Maine to Missouri (average of $311). Flying from Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to MO?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Maine to Missouri as you normally would.

Rainfall in Missouri by month

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Maine to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Alaska Airlines

8.0

Very good

9,820 reviews

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Southwest

8.0

Very good

4,277 reviews

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Delta

8.0

Very good

7,898 reviews

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

United Airlines

7.4

Good

8,615 reviews

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Allegiant Air

7.3

Good

731 reviews

Alaska Airlines

8.0

Very good

9,820 reviews

Reviews

1 / 20

10.0

Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

What are the cheapest airlines to fly from Maine to Missouri one-way?
To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $114. Allegiant Air flights start at $143 while deals on Spirit Airlines start at $145 one-way.
Can I find deals for flights from Maine to Missouri that include hotel bookings?
Yes. In addition to deals on Maine to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Maine to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Missouri.
Can I find deals for business class flights from Maine to Missouri?
Yes. Cheapflights offers flight deals from Maine to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Maine to Missouri?
Currently, August is the cheapest month in which you can book a flight from Maine to Missouri (average of $311). Flying from Maine to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Maine to Missouri

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$208	Average$480	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$255	Average$399	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$267	Average$532	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$351	Average$509	FlexibilityNo cancel fee	On-time63%

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$114+ Cheap flights from Maine to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Maine to Missouri with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Maine to Missouri

Keep the following information in mind while searching for Maine to Missouri flight deals. Data was last updated April 1, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Maine to Missouri

Cheapest flights from Maine to MissouriExplore the most affordable flight options available from Maine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Explore the most affordable flight options available from Maine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Maine to Missouri that are best for you.

Best time to book a flight from Maine to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Maine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Maine to Missouri

What is the cheapest month to book a flight from Maine to Missouri?

What is the cheapest time of day to fly from ME to MO?

Find hourly flight availability from Maine to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Maine to Missouri to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Maine to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines to fly from Maine to Missouri one-way?

Can I find deals for flights from Maine to Missouri that include hotel bookings?

How can I find direct flights from Maine to Missouri?

Can I find deals for business class flights from Maine to Missouri?

What is the cheapest month to book a flight from Maine to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Maine to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Maine to Missouri

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Travel Smart

Cheapest flights from Maine to Missouri
Explore the most affordable flight options available from Maine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.