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$197+ Cheap flights from Knoxville (TYS) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — STL
Nov 26 — Dec 31
Tue 11/26
Tue 12/3
1 adult, Economy
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Cheap flight deals from Knoxville to Missouri

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missouri (USMO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 21, 2024.

Find flight deals from Knoxville to Missouri

Cheapest flights from Knoxville to Missouri
Explore the most affordable flight options available from Knoxville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 21, 2024.

This Delta deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/125:20 amTYS - STL
1 stop5h 02mDelta
Sat 12/147:15 amSTL - TYS
1 stop5h 04mDelta
Deal found 11/20$218
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/189:07 amTYS - STL
2 stops8h 14mAmerican Airlines
Wed 12/255:03 amSTL - TYS
1 stop3h 56mAmerican Airlines
Deal found 11/20$223
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/65:45 amTYS - STL
1 stop5h 31mUnited Airlines
Tue 12/108:25 amSTL - TYS
1 stop5h 15mUnited Airlines
Deal found 11/21$238
This Delta deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/35:30 amTYS - MCI
1 stop4h 55mDelta
Sat 12/76:15 amMCI - TYS
1 stop4h 28mDelta
Deal found 11/19$258
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/57:00 amTYS - SGF
1 stop7h 56mUnited Airlines
Sun 12/88:00 amSGF - TYS
1 stop4h 23mUnited Airlines
Deal found 11/20$283
This American Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/255:24 amTYS - MCI
1 stop8h 16mAmerican Airlines
Sun 12/295:32 amMCI - TYS
1 stop4h 37mAmerican Airlines
Deal found 11/20$293
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/55:30 amTYS - SGF
1 stop7h 08mAmerican Airlines
Sun 12/86:03 pmSGF - TYS
1 stop5h 18mAmerican Airlines
Deal found 11/19$298
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/214:30 pmTYS - MCI
1 stop8h 14mUnited Airlines
Mon 11/256:30 amMCI - TYS
1 stop6h 17mUnited Airlines
Deal found 11/20$338
This Mytrip deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/196:30 amTYS - MCI
1 stop12h 35mMultiple Airlines
Sun 12/227:11 pmMCI - TYS
3 stops21h 23mMultiple Airlines
Deal found 11/21$402
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/25:44 pmTYS - STL
2 stops23h 42mMultiple Airlines
Thu 12/54:26 pmSTL - TYS
2 stops18h 34mMultiple Airlines
Deal found 11/20$455
This United Airlines deal was found by Cheapflights users on 11/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/227:00 amTYS - JLN
1 stop17h 14mUnited Airlines
Sun 11/247:40 amJLN - TYS
1 stop4h 45mUnited Airlines
Deal found 11/21$561
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/197:33 pmTYS - SGF
2 stops24h 45mAllegiant Air
Thu 12/269:02 amSGF - TYS
1 stop8h 04mAllegiant Air
Deal found 11/19$625

Find flights from Knoxville to Missouri within your budget

Customize your flight search to find flights from Knoxville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.

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Route

Depart

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Price

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 1/29

5:45 am-9:53 am

1 stop5h 08m

Kansas City

Sat 2/1

7:10 am-5:16 pm

1 stop9h 06m

$216

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 12/12

5:20 am-9:22 am

1 stop5h 02m

Lambert-St Louis

Sat 12/14

7:15 am-1:19 pm

1 stop5h 04m

$218

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Wed 12/18

9:07 am-4:21 pm

2 stops8h 14m

Lambert-St Louis

Wed 12/25

5:03 am-9:59 am

1 stop3h 56m

$223

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 1/9

5:47 pm-9:45 pm

1 stop4h 58m

Lambert-St Louis

Sun 1/12

5:30 pm-10:36 pm

1 stop4h 06m

$224

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 1/29

5:23 am-9:48 am

1 stop5h 25m

Kansas City

Sun 2/2

10:09 am-6:21 pm

1 stop7h 12m

$228

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Thu 12/5

7:00 am-1:56 pm

1 stop7h 56m

Springfield-Branson

Sun 12/8

8:00 am-1:23 pm

1 stop4h 23m

$283

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 1/29

2:35 pm-8:29 pm

1 stop6h 54m

Kansas City

Sat 2/1

9:55 am-7:36 pm

2 stops8h 41m

$283

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Thu 12/5

5:30 am-11:38 am

1 stop7h 08m

Springfield-Branson

Sun 12/8

6:03 pm-12:21 am

1 stop5h 18m

$298

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Thu 12/19

6:30 am-6:05 pm

1 stop12h 35m

Kansas City

Sun 12/22

7:11 pm-5:34 pm

3 stops21h 23m

$402

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Mon 12/2

5:44 pm-4:26 pm

2 stops23h 42m

Lambert-St Louis

Thu 12/5

4:26 pm-12:00 pm

2 stops18h 34m

$455

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/20

Showing 1-10 of 22 results
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Best time to book a flight from Knoxville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Missouri

Get recent, data-driven insights about flights from Knoxville to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Missouri?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Missouri (average of $308). Flying from Knoxville to Missouri in March is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MO?

Find hourly flight availability from Knoxville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 21, 2024.

When flying from Knoxville to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 21, 2024.
Get a feel of what it's like to fly with American Airlines, United Airlines and Delta from Knoxville to Missouri by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,755 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,755 reviews
Delta
8.0
Very good
8,755 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
9,172 reviews
Delta
8.0
Very good
8,755 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.4
Good
850 reviews
Delta
8.0
Very good
8,755 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,755 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Missouri?

    For a flight from Knoxville to Missouri, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Knoxville to Missouri one-way?

    $200 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Allegiant Air, with prices starting from $219 and $246, respectively.

  • What are the most popular routes from Knoxville to Missouri?

    While some choose either Knoxville McGhee Tyson - Lambert-St Louis or Knoxville McGhee Tyson - Springfield-Branson, Knoxville McGhee Tyson - Kansas City is the most popular route from Knoxville to Missouri.

  • Can I find deals for flights from Knoxville to Missouri that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missouri.

  • Can I find deals for business class flights from Knoxville to Missouri?

    Yes. Cheapflights offers flight deals from Knoxville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Missouri?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Missouri (average of $308). Flying from Knoxville to Missouri in March is currently the most expensive (average of $357). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Missouri

Discover the top 3 airlines that operate flights from Knoxville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,612,795 searches. Data last updated November 21, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$303FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$212Average$324FlexibilityNo cancel feeOn-time71%
DeltaCheapest$213Average$349FlexibilityNo cancel feeOn-timeN/A
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