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$70+ Cheap flights from Knoxville (TYS) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — STL
Dec 31 — Jan 71
Tue 12/31
Tue 1/7
1 adult, Economy
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Cheap flight deals from Knoxville to Missouri

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Missouri (USMO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 26, 2024.

Round-trip from

$109
(Frontier)

One-way from

$70
(Mytrip)
From Knoxville McGhee Tyson to Missouri
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One-way flight from Knoxville McGhee Tyson to Missouri
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Find flight deals from Knoxville to Missouri

Cheapest flights from Knoxville to Missouri
Explore the most affordable flight options available from Knoxville to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2024.

This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/276:41 pmTYS - MCI
1 stop5h 12mAmerican Airlines
Tue 12/311:35 pmMCI - TYS
1 stop7h 23mAmerican Airlines
Deal found 12/25$338
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/306:54 pmTYS - STL
1 stop5h 46mDelta
Mon 1/67:15 amSTL - TYS
1 stop5h 12mDelta
Deal found 12/25$473
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/276:01 pmTYS - SGF
1 stop4h 58mAmerican Airlines
Sun 12/2911:18 amSGF - TYS
1 stop7h 09mAmerican Airlines
Deal found 12/25$543
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2711:50 amTYS - MCI
2 stops11h 06mUnited Airlines
Tue 12/316:00 amMCI - TYS
2 stops7h 43mUnited Airlines
Deal found 12/25$549
This American Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/265:14 amTYS - STL
1 stop6h 31mAmerican Airlines
Thu 12/265:29 pmSTL - TYS
1 stop5h 51mAmerican Airlines
Deal found 12/24$816
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/306:55 amTYS - STL
1 stop4h 52mUnited Airlines
Mon 1/63:10 pmSTL - TYS
2 stops7h 49mUnited Airlines
Deal found 12/25$844
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2711:50 amTYS - SGF
2 stops11h 29mUnited Airlines
Sun 12/297:45 amSGF - TYS
2 stops10h 37mUnited Airlines
Deal found 12/25$1,048
This Mytrip deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/275:58 pmTYS - MCI
3 stops20h 20mMultiple Airlines
Mon 12/307:11 pmMCI - TYS
2 stops25h 15mMultiple Airlines
Deal found 12/25$1,085
This Mytrip deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/271:50 pmTYS - SGF
3 stops31h 21mMultiple Airlines
Sun 12/297:24 pmSGF - TYS
2 stops27h 08mMultiple Airlines
Deal found 12/25$1,411

Find flights from Knoxville to Missouri within your budget

Customize your flight search to find flights from Knoxville to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2024.

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Depart

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Price

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 1/23

4:19 pm-9:16 am

1 stop17h 57m

Lambert-St Louis

Wed 1/29

7:09 pm-3:19 pm

1 stop19h 10m

$109

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Fri 2/7

5:45 am-9:21 am

1 stop4h 36m

Lambert-St Louis

Mon 2/10

7:15 am-1:27 pm

1 stop5h 12m

$228

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Tue 2/25

6:36 pm-10:43 pm

1 stop5h 07m

Lambert-St Louis

Sat 3/1

3:40 pm-11:57 pm

2 stops7h 17m

$233

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Sat 3/29

5:45 am-11:25 am

1 stop6h 40m

Springfield-Branson

Mon 3/31

6:49 pm-11:37 pm

1 stop3h 48m

$248

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 1/29

2:07 pm-5:39 pm

1 stop4h 32m

Kansas City

Sun 2/2

7:10 am-4:13 pm

1 stop8h 03m

$248

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Wed 1/29

2:48 pm-10:22 pm

2 stops8h 34m

Kansas City

Sun 2/2

5:13 am-11:26 am

1 stop5h 13m

$253

KnoxvilleKansas City

TYS - MCI

TYSMCI

Knoxville McGhee Tyson

Thu 1/9

5:45 am-2:29 pm

2 stops9h 44m

Kansas City

Mon 1/13

3:26 pm-10:41 pm

1 stop6h 15m

$263

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Thu 1/30

5:45 am-3:38 pm

2 stops10h 53m

Lambert-St Louis

Sun 2/2

8:00 am-1:18 pm

1 stop4h 18m

$362

KnoxvilleSpringfield

TYS - SGF

TYSSGF

Knoxville McGhee Tyson

Sat 3/29

7:00 am-10:50 am

1 stop4h 50m

Springfield-Branson

Mon 3/31

3:13 pm-11:59 pm

2 stops7h 46m

$416

KnoxvilleSt. Louis

TYS - STL

TYSSTL

Knoxville McGhee Tyson

Sun 1/5

6:46 pm-6:41 pm

3 stops24h 55m

Lambert-St Louis

Sun 1/26

4:28 pm-2:28 pm

2 stops21h 00m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 19 results
1
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Best time to book a flight from Knoxville to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Missouri

Get recent, data-driven insights about flights from Knoxville to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Missouri?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Missouri (average of $311). Flying from Knoxville to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MO?

Find hourly flight availability from Knoxville to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2024.

When flying from Knoxville to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 26, 2024.
Get a feel of what it's like to fly with American Airlines, Delta and United Airlines from Knoxville to Missouri by reading reviews from past customers. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,570 reviews
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
9,002 reviews
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Allegiant Air
7.4
Good
817 reviews
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Frontier
6.1
Okay
3,465 reviews
Delta
8.0
Very good
8,570 reviews

Overall

8.0

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Missouri?

    For a flight from Knoxville to Missouri, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Knoxville to Missouri one-way?

    $70 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $209 and $278, respectively.

  • What are the most popular routes from Knoxville to Missouri?

    While some choose either Knoxville McGhee Tyson - Lambert-St Louis or Knoxville McGhee Tyson - Springfield-Branson, Knoxville McGhee Tyson - Kansas City is the most popular route from Knoxville to Missouri.

  • Can I find deals for flights from Knoxville to Missouri that include hotel bookings?

    Yes. In addition to deals on Knoxville to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Missouri.

  • Can I find deals for business class flights from Knoxville to Missouri?

    Yes. Cheapflights offers flight deals from Knoxville to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Missouri (average of $311). Flying from Knoxville to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Missouri

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Top 3 airlines flying from Knoxville to Missouri

Discover the top 3 airlines that operate flights from Knoxville to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2024.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$313FlexibilityNo cancel feeOn-time69%
DeltaCheapest$213Average$347FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$213Average$325FlexibilityNo cancel feeOn-time71%
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