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Missouri

$49+ Cheap flights from Iowa to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheap flight deals from Iowa to Missouri

Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated April 17, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$252
(Delta)

One-way from

$49
(Southwest)

Good round-trip deal

$339 or less

Good one-way deal

$163 or less
Provider with most accurate pricing for Des Moines-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Kansas City flights.
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From Iowa to Missouri
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One-way flight from Iowa to Missouri
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Price to beat on a round-trip flight from Iowa to Missouri.
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Price to beat on a one-way flight from Iowa to Missouri.
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Find flight deals from Iowa to Missouri

Cheapest flights from Iowa to Missouri
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Booking.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:51 pmOMA - STL
1 stop13h 20mFrontier
Sat 8/167:29 pmSTL - OMA
1 stop23h 24mFrontier
Deal found 4/17$193
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/246:51 pmCID - MCI
1 stop4h 58mAmerican Airlines
Mon 4/285:36 pmMCI - CID
1 stop4h 44mAmerican Airlines
Deal found 4/16$239
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/95:30 pmDSM - STL
1 stop5h 56mDelta
Sun 5/116:00 amSTL - DSM
1 stop6h 27mDelta
Deal found 4/16$252
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/36:00 amOMA - STL
Nonstop1h 15mSouthwest
Thu 6/59:30 amSTL - OMA
Nonstop1h 15mSouthwest
Deal found 4/17$256
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/96:30 pmDSM - MCI
1 stop5h 15mSouthwest
Thu 6/125:10 amMCI - DSM
2 stops5h 20mSouthwest
Deal found 4/16$273
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:32 amDSM - STL
1 stop16h 20mAmerican Airlines
Thu 5/225:00 amSTL - DSM
1 stop18h 39mAmerican Airlines
Deal found 4/17$275
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/711:30 amOMA - STL
1 stop4h 17mUnited Airlines
Fri 5/95:29 pmSTL - OMA
1 stop3h 54mUnited Airlines
Deal found 4/15$281
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:00 amDSM - STL
Nonstop1h 05mSouthwest
Sun 9/1410:40 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 4/16$286
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/198:00 amOMA - SGF
1 stop6h 38mUnited Airlines
Sun 4/208:00 amSGF - OMA
1 stop6h 25mUnited Airlines
Deal found 4/17$289
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1612:43 pmOMA - STL
1 stop6h 46mAmerican Airlines
Sun 5/185:19 amSTL - OMA
1 stop6h 34mAmerican Airlines
Deal found 4/16$331
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/22:28 pmDSM - MCI
2 stops24h 58mMultiple Airlines
Sun 5/46:14 pmMCI - DSM
1 stop28h 07mMultiple Airlines
Deal found 4/16$347
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:55 pmOMA - MCI
1 stop5h 30mSouthwest
Fri 5/306:50 amMCI - OMA
1 stop6h 25mSouthwest
Deal found 4/17$357

Cheapflights Fare Finder

Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.

Fly from

Iowa

Fly to

Missouri

Route

Depart

Return

Price

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 8/12

7:51 pm-9:11 am

1 stop13h 20m

Lambert-St Louis

Sat 8/16

7:29 pm-6:53 pm

1 stop23h 24m

$193

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 5/9

5:30 pm-11:26 pm

1 stop5h 56m

Lambert-St Louis

Sun 5/11

6:00 am-12:27 pm

1 stop6h 27m

$252

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 6/3

6:00 am-7:15 am

Nonstop1h 15m

Lambert-St Louis

Thu 6/5

9:30 am-10:45 am

Nonstop1h 15m

$256

Cedar RapidsKansas City

CID - MCI

CIDMCI

Cedar Rapids

Fri 8/15

7:57 pm-11:59 pm

1 stop4h 02m

Kansas City

Sun 8/17

6:18 pm-10:45 pm

1 stop4h 27m

$269

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Mon 6/9

6:30 pm-11:45 pm

1 stop5h 15m

Kansas City

Thu 6/12

5:10 am-10:30 am

2 stops5h 20m

$273

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 5/15

5:32 am-9:52 pm

1 stop16h 20m

Lambert-St Louis

Thu 5/22

5:00 am-11:39 pm

1 stop18h 39m

$275

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 9/12

6:00 am-7:05 am

Nonstop1h 05m

Lambert-St Louis

Sun 9/14

10:40 pm-11:50 pm

Nonstop1h 10m

$286

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Wed 7/9

11:28 am-3:47 pm

1 stop4h 19m

Lambert-St Louis

Mon 7/14

8:00 am-2:22 pm

1 stop6h 22m

$316

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 5/16

12:43 pm-7:29 pm

1 stop6h 46m

Lambert-St Louis

Sun 5/18

5:19 am-11:53 am

1 stop6h 34m

$331

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Fri 5/2

2:28 pm-3:26 pm

2 stops24h 58m

Kansas City

Sun 5/4

6:14 pm-10:21 pm

1 stop28h 07m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 43 results
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Best time to book a flight from Iowa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Missouri

What is the cheapest month to book a flight from Iowa to Missouri?

Currently, August is the cheapest month in which you can book a flight from Iowa to Missouri (average of $311). Flying from Iowa to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MO?

Find hourly flight availability from Iowa to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

When flying from Iowa to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 17, 2025.
Get a feel of what it's like to fly with Alaska Airlines, Southwest and Delta from Iowa to Missouri by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,882 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,280 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,917 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,667 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,882 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Iowa to Missouri flight route?

    Within the past month, 23 users have taken a look at flights from Iowa to Missouri.

  • What are the cheapest airlines to fly from Iowa to Missouri one-way?

    One-way options have recently been found by users for as low as $49 on Southwest. Other airlines that offer cheap prices include United Airlines from $80 and Delta from $89 one-way.

  • Can I find deals for flights from Iowa to Missouri that include hotel bookings?

    Yes. In addition to deals on Iowa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Missouri.

  • Can I find deals for business class flights from Iowa to Missouri?

    Yes. Cheapflights offers flight deals from Iowa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Missouri (average of $311). Flying from Iowa to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Missouri

Discover the top 4 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$117Average$310FlexibilityNo cancel feeOn-time63%
DeltaCheapest$155Average$470FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$340FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$340FlexibilityNo cancel feeOn-time71%

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