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$49+ Cheap flights from Indiana to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
IND — STL
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
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Cheap flight deals from Indiana to Missouri

Keep the following information in mind while searching for Indiana to Missouri flight deals. Data was last updated April 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$91
(American Airlines)

One-way from

$49
(Southwest)

Popular in

February

Cheapest in

September

Average price

$422

Good round-trip deal

$309 or less

Good one-way deal

$151 or less
Provider with most accurate pricing for Indianapolis-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Indianapolis-Kansas City flights.
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From Indiana to Missouri
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One-way flight from Indiana to Missouri
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Highest demand for flights based on searches. 15% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Indiana to Missouri.
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Price to beat on a one-way flight from Indiana to Missouri.
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Find flight deals from Indiana to Missouri

Cheapest flights from Indiana to Missouri
Explore the most affordable flight options available from Indiana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 24, 2025.

This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:30 pmORD - STL
Nonstop1h 21mAmerican Airlines
Mon 5/197:30 pmSTL - ORD
Nonstop1h 20mAmerican Airlines
Deal found 4/23$91
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:45 amMDW - STL
1 stop5h 00mSouthwest
Mon 5/194:10 pmSTL - MDW
1 stop3h 50mSouthwest
Deal found 4/23$97
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/214:00 pmORD - STL
1 stop6h 10mSouthwest
Wed 5/282:20 pmSTL - ORD
1 stop7h 10mSouthwest
Deal found 4/23$97
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:20 pmORD - STL
Nonstop1h 27mUnited Airlines
Mon 5/199:40 amSTL - ORD
Nonstop1h 30mUnited Airlines
Deal found 4/23$137
This Southern / Mokulele deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southern / Mokulele is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/158:25 amORD - STL
1 stop11h 45mSouthern / Mokulele
Sun 5/1812:15 pmSTL - ORD
1 stop19h 25mSouthern / Mokulele
Deal found 4/23$140
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:39 amIND - MCI
1 stop7h 19mAmerican Airlines
Tue 5/276:33 pmMCI - IND
1 stop4h 30mAmerican Airlines
Deal found 4/23$159
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/167:29 pmCVG - STL
1 stop5h 45mFrontier
Mon 5/195:45 pmSTL - CVG
1 stop6h 14mFrontier
Deal found 4/22$160
This Frontier deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/45:03 pmORD - STL
1 stop6h 34mFrontier
Wed 6/115:35 pmSTL - ORD
1 stop13h 34mFrontier
Deal found 4/22$162
This CheapOair deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/32:44 pmMDW - STL
1 stop19h 24mFrontier
Wed 6/48:11 pmSTL - MDW
1 stop24h 42mFrontier
Deal found 4/23$163
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/234:10 pmCVG - MCI
1 stop8h 49mAmerican Airlines
Mon 7/285:44 amMCI - CVG
1 stop8h 39mAmerican Airlines
Deal found 4/23$171
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/212:07 pmIND - MCI
1 stop3h 43mDelta
Tue 5/275:48 pmMCI - IND
1 stop5h 11mDelta
Deal found 4/22$177
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/410:25 amMDW - STL
1 stop4h 10mDelta
Wed 6/116:00 amSTL - MDW
1 stop5h 59mDelta
Deal found 4/22$177

Cheapflights Fare Finder

Customize your flight search to find flights from Indiana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from Indiana to Missouri that are best for you.

Fly from

Indiana

Fly to

Missouri

Route

Depart

Return

Price

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Tue 5/13

1:59 pm-3:21 pm

Nonstop1h 22m

Lambert-St Louis

Tue 5/13

7:30 pm-8:50 pm

Nonstop1h 20m

$91

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 5/15

5:45 am-10:45 am

1 stop5h 00m

Lambert-St Louis

Mon 5/19

4:10 pm-8:00 pm

1 stop3h 50m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 5/21

5:45 pm-11:00 pm

1 stop5h 15m

Lambert-St Louis

Wed 5/28

5:20 am-10:45 am

1 stop5h 25m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 5/15

2:20 pm-3:47 pm

Nonstop1h 27m

Lambert-St Louis

Mon 5/19

9:40 am-11:10 am

Nonstop1h 30m

$137

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Fri 5/23

8:25 am-8:10 pm

1 stop11h 45m

Lambert-St Louis

Sun 5/25

12:15 pm-3:50 pm

1 stop3h 35m

$140

IndianapolisKansas City

IND - MCI

INDMCI

Indianapolis

Tue 5/20

5:39 am-11:58 am

1 stop7h 19m

Kansas City

Tue 5/27

6:33 pm-12:03 am

1 stop4h 30m

$159

CincinnatiSt. Louis

CVG - STL

CVGSTL

Cincinnati Cinci./N. Kentucky

Fri 5/16

7:29 pm-12:14 am

1 stop5h 45m

Lambert-St Louis

Mon 5/19

5:45 pm-12:59 am

1 stop6h 14m

$160

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Wed 6/4

5:03 pm-11:37 pm

1 stop6h 34m

Lambert-St Louis

Wed 6/11

5:35 pm-7:09 am

1 stop13h 34m

$162

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 6/3

2:44 pm-10:08 am

1 stop19h 24m

Lambert-St Louis

Wed 6/4

8:11 pm-8:53 pm

1 stop24h 42m

$163

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Sat 5/24

5:03 pm-11:44 pm

1 stop6h 41m

Lambert-St Louis

Sun 5/25

12:15 pm-7:40 am

1 stop19h 25m

$164

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/23

Showing 1-10 of 60 results
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Best time to book a flight from Indiana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to Missouri

What is the cheapest month to book a flight from Indiana to Missouri?

Currently, August is the cheapest month in which you can book a flight from Indiana to Missouri (average of $311). Flying from Indiana to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to MO?

Find hourly flight availability from Indiana to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 24, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indiana to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 24, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Indiana to Missouri to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,918 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Southwest
8.0
Very good
4,286 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,920 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,685 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,918 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Entertainment

7.1

Comfort

7.9

Food

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Indiana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Indiana to Missouri one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $49. United Airlines flights start at $68 while deals on Southern / Mokulele start at $73 one-way.

  • Can I find deals for flights from Indiana to Missouri that include hotel bookings?

    Yes. In addition to deals on Indiana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to Missouri.

  • Can I find deals for business class flights from Indiana to Missouri?

    Yes. Cheapflights offers flight deals from Indiana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Indiana to Missouri (average of $311). Flying from Indiana to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Indiana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Indiana to Missouri

Discover the top 4 airlines that operate flights from Indiana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$164Average$394FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$186Average$360FlexibilityNo cancel feeOn-time71%
DeltaCheapest$198Average$343FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$256Average$356FlexibilityNo cancel feeOn-time63%

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