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$55+ Cheap flights from Durham, NC to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — STL
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Durham to Missouri

Discover tips and strategies to find the most affordable flight options for your journey from Durham (DU8) to Missouri (USMO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$130
(FlightHub)

One-way from

$55
(Frontier)
From Durham to Missouri
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One-way flight from Durham to Missouri
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Find flight deals from Durham to Missouri

Cheapest flights from Durham to Missouri
Explore the most affordable flight options available from Durham to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This FlightHub deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2810:16 pmRDU - STL
1 stop26h 27mFrontier
Mon 3/35:20 pmSTL - RDU
1 stop26h 56mFrontier
Deal found 1/21$130
This CheapOair deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/212:17 pmRDU - MCI
1 stop25h 46mMultiple Airlines
Mon 2/248:35 pmMCI - RDU
1 stop18h 45mMultiple Airlines
Deal found 1/19$197
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/197:00 amRDU - SGF
1 stop5h 22mAmerican Airlines
Wed 3/263:52 pmSGF - RDU
1 stop5h 03mAmerican Airlines
Deal found 1/20$199
This FlightHub deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/39:59 pmRDU - STL
1 stop26h 32mMultiple Airlines
Thu 2/64:28 pmSTL - RDU
1 stop16h 23mMultiple Airlines
Deal found 1/20$211
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/310:46 amRDU - STL
1 stop28h 57mSpirit Airlines
Thu 2/64:28 pmSTL - RDU
1 stop19h 53mSpirit Airlines
Deal found 1/21$239
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/55:30 amRDU - MCI
1 stop5h 33mDelta
Sat 2/86:15 amMCI - RDU
1 stop5h 01mDelta
Deal found 1/21$277
This Delta deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:30 amRDU - STL
1 stop5h 05mDelta
Mon 5/195:40 pmSTL - RDU
1 stop3h 55mDelta
Deal found 1/21$277
This CheapOair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/142:17 pmRDU - MCI
1 stop25h 46mSpirit Airlines
Fri 2/214:17 pmMCI - RDU
1 stop16h 47mSpirit Airlines
Deal found 1/21$283
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/295:20 pmRDU - MCI
1 stop6h 05mSouthwest
Fri 5/25:35 pmMCI - RDU
1 stop3h 50mSouthwest
Deal found 1/21$297
This Southwest deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/228:00 pmRDU - STL
1 stop4h 00mSouthwest
Tue 2/258:55 amSTL - RDU
1 stop8h 15mSouthwest
Deal found 1/21$297
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2210:10 amRDU - STL
1 stop8h 50mAmerican Airlines
Tue 2/257:30 amSTL - RDU
1 stop3h 26mAmerican Airlines
Deal found 1/21$312
This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/89:30 amRDU - STL
1 stop6h 01mUnited Airlines
Thu 3/136:30 amSTL - RDU
1 stop6h 43mUnited Airlines
Deal found 1/21$331

Find flights from Durham to Missouri within your budget

Customize your flight search to find flights from Durham to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Fri 2/28

10:16 pm-11:43 pm

1 stop26h 27m

Lambert-St Louis

Mon 3/3

5:20 pm-9:16 pm

1 stop26h 56m

$130

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Fri 2/28

10:16 pm-11:43 pm

1 stop26h 27m

Lambert-St Louis

Sun 3/2

4:00 pm-1:12 pm

1 stop20h 12m

$174

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Fri 2/21

2:17 pm-3:03 pm

1 stop25h 46m

Kansas City

Mon 2/24

8:35 pm-4:20 pm

1 stop18h 45m

$197

RaleighSpringfield

RDU - SGF

RDUSGF

Raleigh-Durham

Wed 3/19

7:00 am-11:22 am

1 stop5h 22m

Springfield-Branson

Wed 3/26

3:52 pm-9:55 pm

1 stop5h 03m

$199

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Mon 2/3

10:46 am-2:43 pm

1 stop28h 57m

Lambert-St Louis

Thu 2/6

4:28 pm-1:21 pm

1 stop19h 53m

$239

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Wed 2/5

5:30 am-10:03 am

1 stop5h 33m

Kansas City

Sat 2/8

6:15 am-12:16 pm

1 stop5h 01m

$277

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Thu 5/15

10:30 am-2:35 pm

1 stop5h 05m

Lambert-St Louis

Mon 5/19

5:40 pm-10:35 pm

1 stop3h 55m

$277

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Fri 2/14

2:17 pm-3:03 pm

1 stop25h 46m

Kansas City

Fri 2/21

4:17 pm-10:04 am

1 stop16h 47m

$283

RaleighKansas City

RDU - MCI

RDUMCI

Raleigh-Durham

Tue 4/29

5:20 pm-10:25 pm

1 stop6h 05m

Kansas City

Fri 5/2

5:35 pm-10:25 pm

1 stop3h 50m

$297

RaleighSt. Louis

RDU - STL

RDUSTL

Raleigh-Durham

Sat 2/22

8:00 pm-11:00 pm

1 stop4h 00m

Lambert-St Louis

Tue 2/25

8:55 am-6:10 pm

1 stop8h 15m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 33 results
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Best time to book a flight from Durham to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Durham to Missouri

Get recent, data-driven insights about flights from Durham to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Durham to Missouri?

Currently, August is the cheapest month in which you can book a flight from Durham to Missouri (average of $311). Flying from Durham to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to MO?

Find hourly flight availability from Durham to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Durham to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Durham to Missouri

Explore weekly flight availability from Durham to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2025.

The most flights from DU8 to USMO are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 21, 2025.
To help decide which airline to fly from Durham to Missouri, see what other customers have to say about Frontier, Southwest and Spirit Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Alaska Airlines
8.0
Very good
9,706 reviews
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,985 reviews
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,662 reviews

Crew

8.7

Overall

8.1

Food

7.2

Boarding

8.2

Comfort

8.1

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Durham to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Durham to Missouri flight route?

    Within the past month, 8 users have taken a look at flights from Durham to Missouri.

  • What are the cheapest airlines to fly from Durham to Missouri one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $55. Delta flights start at $139 while deals on United Airlines start at $144 one-way.

  • What are the most popular routes from Durham to Missouri?

    When deciding which route to take from Durham to Missouri consider Raleigh-Durham - Kansas City, Raleigh-Durham - Lambert-St Louis or Raleigh-Durham - Springfield-Branson as they are the most popular.

  • What are the cheapest flights from Durham to Missouri?

    Looking for the cheapest flight from Durham to Missouri? While on average our users pay $381, our data indicates the cheapest price to be $169. The most popular route (Raleigh-Durham - Kansas City), is priced around $217.

  • Can I find deals for flights from Durham to Missouri that include hotel bookings?

    Yes. In addition to deals on Durham to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Missouri.

  • Can I find deals for business class flights from Durham to Missouri?

    Yes. Cheapflights offers flight deals from Durham to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Durham to Missouri (average of $311). Flying from Durham to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Durham to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Durham to Missouri

Discover the top 6 airlines that operate flights from Durham to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$85Average$176FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$176Average$374FlexibilityNo cancel feeOn-time63%
Spirit AirlinesCheapest$191Average$222FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$198Average$434FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$216Average$425FlexibilityNo cancel feeOn-time71%
DeltaCheapest$218Average$377FlexibilityNo cancel feeOn-timeN/A
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