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$78+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — STL
Mar 30 — Apr 61
Sun 3/30
Sun 4/6
1 adult, Economy
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Cheap flight deals from Detroit to Missouri

Keep the following information in mind while searching for Detroit to Missouri flight deals. Data was last updated March 25, 2025.

Round-trip from

$245
(Delta)

One-way from

$78
(FlightHub)

Good round-trip deal

$279 or less

Good one-way deal

$160 or less
From Detroit Metropolitan Wayne County to Missouri
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One-way flight from Detroit Metropolitan Wayne County to Missouri
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Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Missouri.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Missouri.
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Find flight deals from Detroit to Missouri

Cheapest flights from Detroit to Missouri
Explore the most affordable flight options available from Detroit to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 25, 2025.

This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/228:55 amDTW - STL
Nonstop1h 40mDelta
Thu 5/292:15 pmSTL - DTW
Nonstop1h 31mDelta
Deal found 3/23$245
This FlightHub deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/169:58 pmDTW - STL
1 stop27h 08mFrontier
Sun 5/185:47 pmSTL - DTW
1 stop23h 13mFrontier
Deal found 3/23$247
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/712:20 pmDTW - STL
1 stop21h 55mMultiple Airlines
Wed 5/1412:15 pmSTL - DTW
3 stops35h 14mMultiple Airlines
Deal found 3/23$248
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/185:25 amDTW - STL
1 stop6h 59mAmerican Airlines
Sun 4/209:18 amSTL - DTW
1 stop4h 25mAmerican Airlines
Deal found 3/22$250
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/197:10 amDTW - STL
Nonstop1h 35mSouthwest
Mon 4/214:35 pmSTL - DTW
1 stop3h 25mSouthwest
Deal found 3/24$251
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2111:38 amDTW - MCI
2 stops13h 49mSpirit Airlines
Tue 6/246:43 pmMCI - DTW
1 stop12h 24mSpirit Airlines
Deal found 3/24$281
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/165:18 pmDTW - STL
1 stop16h 57mSpirit Airlines
Sun 5/1810:10 amSTL - DTW
2 stops29h 03mSpirit Airlines
Deal found 3/24$284
This Mytrip deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/252:53 pmDTW - MCI
3 stops25h 33mMultiple Airlines
Sun 4/2710:25 amMCI - DTW
1 stop21h 18mMultiple Airlines
Deal found 3/22$298
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:20 amDTW - MCI
2 stops7h 20mSouthwest
Fri 5/305:25 amMCI - DTW
1 stop3h 35mSouthwest
Deal found 3/22$322
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2911:45 amDTW - MCI
1 stop7h 00mAmerican Airlines
Thu 5/13:49 pmMCI - DTW
1 stop7h 15mAmerican Airlines
Deal found 3/24$327
This Mytrip deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/176:20 amDTW - SGF
1 stop14h 18mMultiple Airlines
Sat 4/263:07 pmSGF - DTW
1 stop13h 46mMultiple Airlines
Deal found 3/23$327
This Booking.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/298:27 pmDTW - MCI
1 stop24h 08mFrontier
Mon 3/318:35 pmMCI - DTW
1 stop16h 17mFrontier
Deal found 3/24$328

Cheapflights Fare Finder

Customize your flight search to find flights from Detroit to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Missouri that are best for you.

Fly from

Detroit

Fly to

Missouri

Route

Depart

Return

Price

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Thu 5/22

8:55 am-9:35 am

Nonstop1h 40m

Lambert-St Louis

Thu 5/29

2:15 pm-4:46 pm

Nonstop1h 31m

$245

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 5/16

9:58 pm-12:06 am

1 stop27h 08m

Lambert-St Louis

Sun 5/18

5:47 pm-6:00 pm

1 stop23h 13m

$247

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Wed 5/7

12:20 pm-9:15 am

1 stop21h 55m

Lambert-St Louis

Wed 5/14

12:15 pm-12:29 am

3 stops35h 14m

$248

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 4/18

5:25 am-11:24 am

1 stop6h 59m

Lambert-St Louis

Sun 4/20

9:18 am-2:43 pm

1 stop4h 25m

$250

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Sat 4/19

7:10 am-7:45 am

Nonstop1h 35m

Lambert-St Louis

Mon 4/21

4:35 pm-9:00 pm

1 stop3h 25m

$251

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Sat 6/21

11:38 am-12:27 am

2 stops13h 49m

Kansas City

Tue 6/24

6:43 pm-8:07 am

1 stop12h 24m

$281

DetroitSt. Louis

DTW - STL

DTWSTL

Detroit Metropolitan Wayne County

Fri 5/16

5:18 pm-9:15 am

1 stop16h 57m

Lambert-St Louis

Sun 5/18

10:10 am-4:13 pm

2 stops29h 03m

$284

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Fri 4/25

2:53 pm-3:26 pm

3 stops25h 33m

Kansas City

Sun 4/27

10:25 am-8:43 am

1 stop21h 18m

$298

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Sat 5/24

6:20 am-12:40 pm

2 stops7h 20m

Kansas City

Fri 5/30

5:25 am-10:00 am

1 stop3h 35m

$322

DetroitKansas City

DTW - MCI

DTWMCI

Detroit Metropolitan Wayne County

Tue 4/29

11:45 am-5:45 pm

1 stop7h 00m

Kansas City

Thu 5/1

3:49 pm-12:04 am

1 stop7h 15m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 37 results
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Best time to book a flight from Detroit to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Missouri

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Missouri?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Missouri (average of $311). Flying from Detroit Metropolitan Wayne County Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to MO?

Find hourly flight availability from Detroit to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 25, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to Missouri

Explore weekly flight availability from Detroit to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 25, 2025.

The most flights from DTW to USMO are scheduled on a Monday (15 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (12 on average).

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 25, 2025.
To help decide which airline to fly from Detroit to Missouri, see what other customers have to say about Alaska Airlines, Southwest and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Alaska Airlines
8.0
Very good
9,785 reviews
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Southwest
8.0
Very good
4,272 reviews
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
Delta
8.0
Very good
7,890 reviews
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
United Airlines
7.4
Good
8,605 reviews
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,785 reviews

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.1

Comfort

7.9

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Cheri,Jan 2025

FAT - SEA

Very friendly. I really liked that they had water for us in cartons not plastic. Impressed with Alaska Airlines, First time I had flown them

Related info for your journey

Find useful and relevant information for your journey from Detroit to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Missouri?

    For a flight from Detroit to Missouri, you will be flying from Detroit Metropolitan Wayne County. Detroit Metropolitan Wayne County (DTW) is just 17.3 mi from the center of the city.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to Missouri one-way?

    $78 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on American Airlines and Frontier, with prices starting from $97 and $110, respectively.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to Missouri?

    When deciding which route to take from Detroit Metropolitan Wayne County Airport to Missouri consider Detroit Metropolitan Wayne County - Kansas City, Detroit Metropolitan Wayne County - Lambert-St Louis or Detroit Metropolitan Wayne County - Springfield-Branson as they are the most popular.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Missouri?

    Before booking your flight to Missouri from Detroit Metropolitan Wayne County Airport, check out the most reliable airlines to get you to your destination on time: SkyWest Airlines (100%), Endeavor Airlines (100%), Aeromexico( 89%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Missouri?

    Looking for the cheapest flight from Detroit Metropolitan Wayne County Airport to Missouri? While on average our users pay $297, our data indicates the cheapest price to be $109. The most popular route (Detroit Metropolitan Wayne County - Kansas City), is priced around $158.

  • Can I find deals for flights from Detroit to Missouri that include hotel bookings?

    Yes. In addition to deals on Detroit to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Missouri.

  • Can I find deals for business class flights from Detroit to Missouri?

    Yes. Cheapflights offers flight deals from Detroit to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Missouri (average of $311). Flying from Detroit Metropolitan Wayne County Airport to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Detroit to Missouri

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Top 6 airlines flying from Detroit to Missouri

Discover the top 6 airlines that operate flights from Detroit to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$49Average$201FlexibilityNo cancel feeOn-time65%
FrontierCheapest$124Average$200FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$179Average$441FlexibilityNo cancel feeOn-time71%
DeltaCheapest$199Average$371FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$245Average$350FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$298Average$536FlexibilityNo cancel feeOn-time69%
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