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$49+ Cheap flights from Des Moines (DSM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
mar. 30 — abr. 61
dom. 3/30
dom. 4/6
1 adult, Economy
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Cheap flight deals from Des Moines to Missouri

Keep the following information in mind while searching for Des Moines to Missouri flight deals. Data was last updated marzo 25, 2025.

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Good round-trip deal

$357 or less

Good one-way deal

$179 or less
From Des Moines to Missouri
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One-way flight from Des Moines to Missouri
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Price to beat on a round-trip flight from Des Moines to Missouri.
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Price to beat on a one-way flight from Des Moines to Missouri.
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Find flight deals from Des Moines to Missouri

Cheapest flights from Des Moines to Missouri
Explore the most affordable flight options available from Des Moines to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 25, 2025.

This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/146:00 amDSM - STL
Nonstop1h 05mSouthwest
lun. 4/149:55 pmSTL - DSM
Nonstop1h 10mSouthwest
Deal found 3/23$97
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/76:13 pmDSM - STL
1 stop3h 39mAmerican Airlines
mié. 5/147:30 pmSTL - DSM
1 stop4h 09mAmerican Airlines
Deal found 3/24$139
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/266:30 amDSM - STL
1 stop6h 31mDelta
sáb. 4/265:33 pmSTL - DSM
1 stop3h 40mDelta
Deal found 3/24$177
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/73:20 pmDSM - STL
1 stop6h 43mUnited Airlines
mié. 5/146:30 amSTL - DSM
1 stop4h 00mUnited Airlines
Deal found 3/23$237
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/143:40 pmDSM - MCI
1 stop8h 50mSouthwest
mar. 4/225:50 amMCI - DSM
1 stop5h 45mSouthwest
Deal found 3/24$255
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/83:44 pmDSM - STL
3 stops28h 26mMultiple Airlines
jue. 5/1510:10 amSTL - DSM
1 stop29h 43mMultiple Airlines
Deal found 3/24$387
This Mytrip deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/287:30 amDSM - MCI
1 stop7h 56mMultiple Airlines
dom. 3/306:50 pmMCI - DSM
1 stop27h 42mMultiple Airlines
Deal found 3/24$522
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/85:45 amDSM - MCI
1 stop14h 54mUnited Airlines
sáb. 4/129:08 amMCI - DSM
1 stop11h 31mUnited Airlines
Deal found 3/24$612

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 25, 2025.
Use the filters below to find and compare flights from Des Moines to Missouri that are best for you.

Fly from

Des Moines

Fly to

Missouri

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

lun. 4/14

6:00 am-7:05 am

Nonstop1h 05m

Lambert-St Louis

lun. 4/14

9:55 pm-11:05 pm

Nonstop1h 10m

$97

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

mié. 5/7

6:13 pm-9:52 pm

1 stop3h 39m

Lambert-St Louis

mié. 5/14

7:30 pm-11:39 pm

1 stop4h 09m

$139

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

sáb. 4/26

6:30 am-1:01 pm

1 stop6h 31m

Lambert-St Louis

sáb. 4/26

5:33 pm-9:13 pm

1 stop3h 40m

$177

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

mié. 5/7

3:20 pm-10:03 pm

1 stop6h 43m

Lambert-St Louis

mié. 5/14

6:30 am-10:30 am

1 stop4h 00m

$237

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

lun. 4/14

3:40 pm-12:30 am

1 stop8h 50m

Kansas City

mar. 4/22

5:50 am-11:35 am

1 stop5h 45m

$255

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

jue. 5/8

3:44 pm-8:10 pm

3 stops28h 26m

Lambert-St Louis

jue. 5/15

10:10 am-3:53 pm

1 stop29h 43m

$387

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

mar. 4/8

5:45 am-8:39 pm

1 stop14h 54m

Kansas City

sáb. 4/12

9:08 am-8:39 pm

1 stop11h 31m

$612

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

jue. 4/24

6:00 am-7:05 am

Nonstop1h 05m

$49

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

vie. 4/25

6:14 pm-11:33 pm

1 stop5h 19m

$70

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

jue. 4/24

8:00 am-2:42 pm

1 stop6h 42m

$89

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 15 results
1
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Best time to book a flight from Des Moines to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Missouri

What is the cheapest month to book a flight from Des Moines to Missouri?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Missouri (average of $311). Flying from Des Moines to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MO?

Find hourly flight availability from Des Moines to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated marzo 25, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated marzo 25, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Missouri. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.0
Very good
4,272 reviews
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,890 reviews
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,605 reviews
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,273 reviews
Southwest
8.0
Very good
4,272 reviews

Overall

8.0

Food

7.1

Comfort

8.0

Boarding

8.2

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Missouri?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Missouri. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • How popular is this Des Moines to Missouri flight route?

    The Des Moines to Missouri flight path was viewed by 20 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Des Moines to Missouri one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Des Moines to Missouri for a low price.

  • What are the cheapest flights from Des Moines to Missouri?

    The cheapest flight price from Des Moines to Missouri is $78. On average you can expect to pay $316. The most popular route, (Des Moines - Lambert-St Louis), can usually be booked for $132.

  • Can I find deals for flights from Des Moines to Missouri that include hotel bookings?

    Yes. In addition to deals on Des Moines to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Missouri.

  • Can I find deals for business class flights from Des Moines to Missouri?

    Yes. Cheapflights offers flight deals from Des Moines to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Missouri (average of $311). Flying from Des Moines to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Cedar Rapids to Orlando flights
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Omaha to Dulles Intl flights
Moline to Dallas/Fort Worth flights
Omaha to Hobby flights
Omaha to Fort Lauderdale flights
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Des Moines to Salt Lake City flights
Des Moines to San Francisco flights
Cedar Rapids to John F Kennedy Intl flights
Moline to Denver flights
Moline to Orlando flights
Des Moines to Dulles Intl flights
Omaha to San Diego flights
Cedar Rapids to Miami flights
Omaha to Portland flights

Top 2 airlines flying from Des Moines to Missouri

Discover the top 2 airlines that operate flights from Des Moines to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$127Average$312FlexibilityNo cancel feeOn-time63%
DeltaCheapest$155Average$470FlexibilityNo cancel feeOn-timeN/A
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