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$81+ Cheap flights from Des Moines (DSM) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Jan 21 — Jan 281
Tue 1/21
Tue 1/28
1 adult, Economy
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Cheap flight deals from Des Moines to Missouri

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Missouri (USMO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 16, 2025.

Round-trip from

$309
(Southwest)

One-way from

$81
(Frontier)
From Des Moines to Missouri
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One-way flight from Des Moines to Missouri
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Find flight deals from Des Moines to Missouri

Cheapest flights from Des Moines to Missouri
Explore the most affordable flight options available from Des Moines to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

This Southwest deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/215:30 amDSM - STL
Nonstop1h 20mSouthwest
Tue 2/2510:00 amSTL - DSM
1 stop9h 00mSouthwest
Deal found 1/16$309
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/16:00 pmDSM - STL
1 stop4h 14mAmerican Airlines
Sat 3/85:37 pmSTL - DSM
1 stop6h 12mAmerican Airlines
Deal found 1/15$310
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/217:00 amDSM - STL
1 stop3h 59mDelta
Tue 2/256:43 amSTL - DSM
2 stops9h 47mDelta
Deal found 1/16$314
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/13:04 pmDSM - STL
3 stops21h 06mMultiple Airlines
Sat 3/810:24 amSTL - DSM
2 stops25h 27mMultiple Airlines
Deal found 1/15$453
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/18:00 amDSM - STL
2 stops12h 44mUnited Airlines
Sat 3/88:00 amSTL - DSM
1 stop6h 52mUnited Airlines
Deal found 1/15$472
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/145:13 pmDSM - MCI
1 stop19h 24mUnited Airlines
Sun 2/169:00 amMCI - DSM
1 stop14h 30mUnited Airlines
Deal found 1/15$512
This Southwest deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/158:00 amDSM - MCI
2 stops11h 10mSouthwest
Wed 3/196:25 amMCI - DSM
1 stop5h 00mSouthwest
Deal found 1/15$522
This Mytrip deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/156:30 pmDSM - MCI
3 stops21h 47mMultiple Airlines
Wed 3/195:12 pmMCI - DSM
1 stop15h 00mMultiple Airlines
Deal found 1/15$724

Find flights from Des Moines to Missouri within your budget

Customize your flight search to find flights from Des Moines to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 2/21

5:30 am-6:50 am

Nonstop1h 20m

Lambert-St Louis

Tue 2/25

10:00 am-7:00 pm

1 stop9h 00m

$309

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 3/1

6:00 pm-10:14 pm

1 stop4h 14m

Lambert-St Louis

Sat 3/8

5:37 pm-11:49 pm

1 stop6h 12m

$310

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 2/21

7:00 am-10:59 am

1 stop3h 59m

Lambert-St Louis

Tue 2/25

6:43 am-4:30 pm

2 stops9h 47m

$314

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 3/1

3:04 pm-12:10 pm

3 stops21h 06m

Lambert-St Louis

Sat 3/8

10:24 am-11:51 am

2 stops25h 27m

$453

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 3/1

8:00 am-8:44 pm

2 stops12h 44m

Lambert-St Louis

Sat 3/8

8:00 am-2:52 pm

1 stop6h 52m

$472

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Fri 2/14

5:13 pm-12:37 pm

1 stop19h 24m

Kansas City

Sun 2/16

9:00 am-11:30 pm

1 stop14h 30m

$512

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Sat 3/15

8:00 am-7:10 pm

2 stops11h 10m

Kansas City

Wed 3/19

6:25 am-11:25 am

1 stop5h 00m

$522

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Sat 3/15

6:30 pm-4:17 pm

3 stops21h 47m

Kansas City

Wed 3/19

5:12 pm-8:12 am

1 stop15h 00m

$724

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 3/19

6:57 pm-7:58 am

1 stop13h 01m

$81

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Mon 2/24

6:10 am-11:25 am

1 stop5h 15m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 15 results
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Best time to book a flight from Des Moines to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Missouri

Get recent, data-driven insights about flights from Des Moines to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Missouri?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Missouri (average of $311). Flying from Des Moines to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MO?

Find hourly flight availability from Des Moines to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 16, 2025.
Read reviews from past customers who have flown United Airlines and Southwest from Des Moines to Missouri. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,659 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,511 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,965 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,435 reviews
Southwest
8.1
Very good
4,659 reviews

Boarding

8.2

Food

7.2

Overall

8.1

Comfort

8.1

Crew

8.7

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Missouri?

    Des Moines (DSM) is the airport you will fly out of if you book a flight from Des Moines to Missouri. It is only a 3.6 mi journey to Des Moines (DSM) from Des Moines’s city center.

  • How popular is this Des Moines to Missouri flight route?

    The Des Moines to Missouri flight path was viewed by 8 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Des Moines to Missouri one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $81. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from Des Moines to Missouri for a low price.

  • What are the cheapest flights from Des Moines to Missouri?

    The cheapest flight price from Des Moines to Missouri is $174. On average you can expect to pay $383. The most popular route, (Des Moines - Lambert-St Louis), can usually be booked for $309.

  • Can I find deals for flights from Des Moines to Missouri that include hotel bookings?

    Yes. In addition to deals on Des Moines to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Missouri.

  • Can I find deals for business class flights from Des Moines to Missouri?

    Yes. Cheapflights offers flight deals from Des Moines to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Missouri (average of $311). Flying from Des Moines to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Des Moines to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Omaha to Honolulu flights
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Omaha to Reagan-National flights
Omaha to Fort Lauderdale flights
Omaha to Nashville flights
Omaha to Newark flights

Top 3 airlines flying from Des Moines to Missouri

Discover the top 3 airlines that operate flights from Des Moines to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$155Average$470FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$168Average$326FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$257Average$435FlexibilityNo cancel feeOn-time71%
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