HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$290+ Cheap flights from the Cayman Islands to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — STL
Apr 29 — May 61
Tue 4/29
Tue 5/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Cayman Islands to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Cayman Islands to Missouri

Keep the following information in mind while searching for Cayman Islands to Missouri flight deals. Data was last updated April 24, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars
Provider with most accurate pricing for George Town Owen Roberts Intl-Kansas City flight deals.
Search Deals
Provider most trusted by Cheapflights users for George Town Owen Roberts Intl-Kansas City flights.
Search Deals

Find flight deals from Cayman Islands to Missouri

One-way flights from Cayman Islands to Missouri
Search for one-way flight options from Cayman Islands to Missouri. Find affordable one-way fares based on user searches. Data last updated April 24, 2025.

This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/41:35 pmGCM - MCI
2 stops32h 12mUnited Airlines
Deal found 4/24$290
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/42:00 pmGCM - MCI
1 stop9h 02mAmerican Airlines
Deal found 4/23$299
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1412:50 pmGCM - MCI
1 stop8h 10mDelta
Deal found 4/23$317
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/412:40 pmGCM - MCI
3 stops26h 46mMultiple Airlines
Deal found 4/23$450

Cheapflights Fare Finder

Customize your flight search to find flights from Cayman Islands to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
Use the filters below to find and compare flights from the Cayman Islands to Missouri that are best for you.

Fly from

Cayman Islands

Fly to

Missouri

Route

Depart

Return

Price

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Sun 5/4

1:35 pm-9:47 pm

2 stops32h 12m

$290

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Sun 5/4

2:00 pm-11:02 pm

1 stop9h 02m

$299

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Mon 7/14

12:50 pm-9:00 pm

1 stop8h 10m

$317

George TownKansas City

GCM - MCI

GCMMCI

George Town Owen Roberts Intl

Sun 5/4

12:40 pm-3:26 pm

3 stops26h 46m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/24

Best time to book a flight from Cayman Islands to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to Missouri

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 24, 2025.
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,920 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,685 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,920 reviews

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Cayman Islands to Missouri one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $290. Users have also found prices from $299 and $317 on American Airlines and Delta, respectively.

  • Can I find deals for flights from Cayman Islands to Missouri that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to Missouri.

  • Can I find deals for business class flights from Cayman Islands to Missouri?

    Yes. Cheapflights offers flight deals from Cayman Islands to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cayman Islands to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Cayman Islands to Missouri (average of $311). Flying from Cayman Islands to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cayman Islands to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Luis Munoz Marin Intl to Orlando flights
Santo Domingo to John F Kennedy Intl flights
Luis Munoz Marin Intl to John F Kennedy Intl flights
Santo Domingo to Newark flights
Santiago de los Caballeros to John F Kennedy Intl flights
Luis Munoz Marin Intl to Newark flights
Santiago de los Caballeros to Newark flights
Luis Munoz Marin Intl to Fort Lauderdale flights
Luis Munoz Marin Intl to Miami flights
Luis Munoz Marin Intl to Tampa flights
Luis Munoz Marin Intl to LaGuardia flights
Luis Munoz Marin Intl to O'Hare Intl flights
Luis Munoz Marin Intl to Philadelphia flights
Santo Domingo to Boston flights
Luis Munoz Marin Intl to Boston flights
Santo Domingo to LaGuardia flights
Santo Domingo to Orlando flights
Luis Munoz Marin Intl to Hartford flights
Kingston to John F Kennedy Intl flights
Ponce to Orlando flights
Luis Munoz Marin Intl to Seattle flights
Port of Spain to John F Kennedy Intl flights
Luis Munoz Marin Intl to Hobby flights
Luis Munoz Marin Intl to Atlanta flights
Luis Munoz Marin Intl to Dulles Intl flights
Luis Munoz Marin Intl to Reagan-National flights
Santo Domingo to Miami flights
Luis Munoz Marin Intl to Baltimore flights
Aguadilla to Orlando flights
Luis Munoz Marin Intl to Dallas/Fort Worth flights
Luis Munoz Marin Intl to George Bush Intcntl flights
Port of Spain to Miami flights
Bridgetown to John F Kennedy Intl flights
Luis Munoz Marin Intl to Raleigh flights
Santo Domingo to Fort Lauderdale flights
Montego Bay to John F Kennedy Intl flights
Luis Munoz Marin Intl to Las Vegas flights
Punta Cana to John F Kennedy Intl flights
Luis Munoz Marin Intl to Denver flights
Luis Munoz Marin Intl to Midway flights
Luis Munoz Marin Intl to Los Angeles flights
Santiago de los Caballeros to LaGuardia flights
Santo Domingo to Atlanta flights
Kingston to Fort Lauderdale flights
Nassau to Miami flights
Oranjestad to Miami flights
Luis Munoz Marin Intl to Charlotte flights
Santiago de los Caballeros to Orlando flights
Luis Munoz Marin Intl to Jacksonville flights
Montego Bay to Newark flights

Top airline flying from Cayman Islands to Missouri

Discover the top airline that operate flights from Cayman Islands to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$418Average$478FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.