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$139+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Feb 26 — Mar 51
Wed 2/26
Wed 3/5
1 adult, Economy
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Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated February 21, 2025.

Round-trip from

$139
(Mytrip)
From Buffalo to Missouri
Search Deals

Find flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 21, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/211:24 amBUF - STL
1 stop13h 22mFrontier
Sat 4/54:57 pmSTL - BUF
1 stop16h 27mFrontier
Deal found 2/20$139
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/196:00 amBUF - SGF
1 stop6h 22mAmerican Airlines
Tue 3/255:33 amSGF - BUF
1 stop4h 16mAmerican Airlines
Deal found 2/20$199
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/36:00 amBUF - STL
1 stop9h 48mAmerican Airlines
Sat 4/56:13 amSTL - BUF
1 stop5h 08mAmerican Airlines
Deal found 2/20$275
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:00 amBUF - MCI
1 stop5h 52mDelta
Tue 3/252:50 pmMCI - BUF
1 stop8h 30mDelta
Deal found 2/21$297
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/26:00 amBUF - STL
2 stops7h 20mUnited Airlines
Sat 4/53:40 pmSTL - BUF
2 stops7h 04mUnited Airlines
Deal found 2/20$298
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/174:20 pmBUF - MCI
2 stops7h 10mAmerican Airlines
Tue 3/253:55 pmMCI - BUF
1 stop7h 25mAmerican Airlines
Deal found 2/21$302
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/206:00 amBUF - SGF
1 stop6h 25mDelta
Tue 3/253:29 pmSGF - BUF
1 stop7h 38mDelta
Deal found 2/20$308
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/55:50 amBUF - MCI
2 stops6h 40mSouthwest
Sat 8/910:30 amMCI - BUF
1 stop3h 45mSouthwest
Deal found 2/19$347
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/305:35 amBUF - STL
2 stops7h 45mSouthwest
Mon 7/145:25 amSTL - BUF
1 stop4h 00mSouthwest
Deal found 2/20$352
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/812:03 pmBUF - STL
1 stop5h 34mDelta
Sun 3/96:50 amSTL - BUF
1 stop4h 20mDelta
Deal found 2/20$367
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:52 pmBUF - MCI
1 stop5h 07mUnited Airlines
Tue 3/1111:36 amMCI - BUF
1 stop4h 19mUnited Airlines
Deal found 2/20$388
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2910:28 amBUF - SGF
2 stops12h 32mUnited Airlines
Thu 7/313:06 pmSGF - BUF
1 stop4h 25mUnited Airlines
Deal found 2/20$579

Find flights from Buffalo to Missouri within your budget

Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 4/2

11:24 am-11:46 pm

1 stop13h 22m

Lambert-St Louis

Sat 4/5

4:57 pm-10:24 am

1 stop16h 27m

$139

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Wed 3/19

6:00 am-11:22 am

1 stop6h 22m

Springfield-Branson

Tue 3/25

5:33 am-10:49 am

1 stop4h 16m

$199

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 4/3

6:00 am-2:48 pm

1 stop9h 48m

Lambert-St Louis

Sat 4/5

6:13 am-12:21 pm

1 stop5h 08m

$275

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Mon 3/17

6:00 am-10:52 am

1 stop5h 52m

Kansas City

Tue 3/25

2:50 pm-12:20 am

1 stop8h 30m

$297

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 4/2

6:00 am-12:20 pm

2 stops7h 20m

Lambert-St Louis

Sat 4/5

3:40 pm-11:44 pm

2 stops7h 04m

$298

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Mon 3/17

4:20 pm-10:30 pm

2 stops7h 10m

Kansas City

Tue 3/25

3:55 pm-12:20 am

1 stop7h 25m

$302

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Thu 3/20

6:00 am-11:25 am

1 stop6h 25m

Springfield-Branson

Tue 3/25

3:29 pm-12:07 am

1 stop7h 38m

$308

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Tue 8/5

5:50 am-11:30 am

2 stops6h 40m

Kansas City

Sat 8/9

10:30 am-3:15 pm

1 stop3h 45m

$347

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 6/30

5:35 am-12:20 pm

2 stops7h 45m

Lambert-St Louis

Mon 7/14

5:25 am-10:25 am

1 stop4h 00m

$352

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 3/8

12:03 pm-4:37 pm

1 stop5h 34m

Lambert-St Louis

Sun 3/9

6:50 am-12:10 pm

1 stop4h 20m

$367

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Buffalo to Missouri

Get recent, data-driven insights about flights from Buffalo to Missouri including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 21, 2025.

When flying from Buffalo to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 21, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Buffalo to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,401 reviews
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Frontier
6.0
Okay
3,354 reviews
Southwest
8.1
Very good
4,401 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $149. American Airlines flights start at $154 while deals on Southwest start at $179 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Kansas City or Buffalo - Springfield-Branson, Buffalo - Lambert-St Louis is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Buffalo to Missouri

Discover the top 6 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$125Average$228FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$197Average$267FlexibilityNo cancel feeOn-time62%
DeltaCheapest$237Average$381FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$387FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$286Average$520FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$296Average$471FlexibilityNo cancel feeOn-time63%
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