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$210+ Cheap flights from Knoxville (TYS) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/7. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — JAN
Jan 22 — Jan 291
Wed 1/22
Wed 1/29
1 adult, Economy
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Cheap flight deals from Knoxville to Mississippi

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mississippi (USMS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 17, 2025.

Round-trip from

$214
(Delta)

One-way from

$210
(American Airlines)
From Knoxville McGhee Tyson to Mississippi
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One-way flight from Knoxville McGhee Tyson to Mississippi
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Find flight deals from Knoxville to Mississippi

Cheapest flights from Knoxville to Mississippi
Explore the most affordable flight options available from Knoxville to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 17, 2025.

This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/267:17 pmTYS - MEM
1 stop5h 00mDelta
Mon 3/35:57 pmMEM - TYS
1 stop4h 50mDelta
Deal found 1/16$214
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/25:45 amTYS - JAN
1 stop3h 58mDelta
Sat 2/85:55 amJAN - TYS
1 stop4h 28mDelta
Deal found 1/16$219
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/135:45 amTYS - GPT
1 stop4h 39mDelta
Thu 2/206:30 amGPT - TYS
1 stop3h 53mDelta
Deal found 1/16$229
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/96:17 pmTYS - BTR
1 stop5h 28mAmerican Airlines
Sat 2/155:30 amBTR - TYS
1 stop5h 01mAmerican Airlines
Deal found 1/15$229
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/16:00 pmTYS - GPT
1 stop5h 06mAmerican Airlines
Mon 3/36:28 pmGPT - TYS
1 stop4h 29mAmerican Airlines
Deal found 1/16$254
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2411:40 amTYS - JAN
1 stop5h 27mUnited Airlines
Mon 1/2712:00 pmJAN - TYS
1 stop5h 08mUnited Airlines
Deal found 1/16$279
This Mytrip deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/176:25 pmTYS - MEM
1 stop14h 22mMultiple Airlines
Thu 3/208:22 amMEM - TYS
1 stop11h 49mMultiple Airlines
Deal found 1/16$298
This American Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/186:11 pmTYS - MEM
1 stop6h 48mAmerican Airlines
Tue 1/216:05 pmMEM - TYS
1 stop4h 53mAmerican Airlines
Deal found 1/16$299
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/247:17 pmTYS - BTR
1 stop4h 06mDelta
Tue 1/286:00 amBTR - TYS
1 stop4h 23mDelta
Deal found 1/16$319
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/166:00 pmTYS - MOB
1 stop5h 15mAmerican Airlines
Tue 2/253:40 pmMOB - TYS
1 stop4h 38mAmerican Airlines
Deal found 1/15$386
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/236:45 amTYS - BTR
1 stop5h 25mUnited Airlines
Mon 1/2712:05 pmBTR - TYS
1 stop5h 03mUnited Airlines
Deal found 1/16$389
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/135:45 amTYS - MOB
1 stop3h 58mDelta
Mon 2/177:04 pmMOB - TYS
1 stop3h 43mDelta
Deal found 1/16$404

Find flights from Knoxville to Mississippi within your budget

Customize your flight search to find flights from Knoxville to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Wed 2/26

7:17 pm-11:17 pm

1 stop5h 00m

Memphis

Mon 3/3

5:57 pm-11:47 pm

1 stop4h 50m

$214

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Sun 2/2

5:45 am-8:43 am

1 stop3h 58m

Jackson-Evers Intl

Sat 2/8

5:55 am-11:23 am

1 stop4h 28m

$219

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sun 2/9

6:17 pm-10:45 pm

1 stop5h 28m

Baton Rouge Ryan

Sat 2/15

5:30 am-11:31 am

1 stop5h 01m

$229

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

Thu 2/13

5:45 am-9:24 am

1 stop4h 39m

Gulfport Biloxi Regional

Thu 2/20

6:30 am-11:23 am

1 stop3h 53m

$229

KnoxvilleGulfport

TYS - GPT

TYSGPT

Knoxville McGhee Tyson

Sat 3/1

6:00 pm-10:06 pm

1 stop5h 06m

Gulfport Biloxi Regional

Mon 3/3

6:28 pm-11:57 pm

1 stop4h 29m

$254

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Mon 3/17

6:25 pm-7:47 am

1 stop14h 22m

Memphis

Thu 3/20

8:22 am-9:11 pm

1 stop11h 49m

$298

KnoxvilleJackson

TYS - JAN

TYSJAN

Knoxville McGhee Tyson

Thu 1/30

6:45 am-11:21 am

1 stop5h 36m

Jackson-Evers Intl

Mon 2/3

5:18 pm-11:46 pm

1 stop5h 28m

$299

KnoxvilleMemphis

TYS - MEM

TYSMEM

Knoxville McGhee Tyson

Wed 4/16

7:59 pm-11:30 pm

1 stop4h 31m

Memphis

Mon 4/21

2:40 pm-9:24 pm

1 stop5h 44m

$304

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Sun 2/16

6:00 pm-10:15 pm

1 stop5h 15m

Mobile

Tue 2/25

3:40 pm-9:18 pm

1 stop4h 38m

$386

KnoxvilleMobile

TYS - MOB

TYSMOB

Knoxville McGhee Tyson

Thu 2/13

5:45 am-8:43 am

1 stop3h 58m

Mobile

Mon 2/17

7:04 pm-11:47 pm

1 stop3h 43m

$404

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Showing 1-10 of 22 results
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Best time to book a flight from Knoxville to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Mississippi

Get recent, data-driven insights about flights from Knoxville to Mississippi including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $371). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MS?

Find hourly flight availability from Knoxville to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 17, 2025.

When flying from Knoxville to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mississippi by month

Plan your trip to Mississippi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

Temperature in Mississippi by month

Plan your trip to Mississippi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated January 17, 2025.
To help decide which airline to fly from Knoxville to Mississippi, see what other customers have to say about Delta, American Airlines and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,511 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,511 reviews
Delta
8.0
Very good
8,511 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
8,965 reviews
Delta
8.0
Very good
8,511 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,511 reviews

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mississippi?

    Most people fly from Knoxville McGhee Tyson (TYS) if they book a flight from Knoxville to Mississippi. Knoxville McGhee Tyson is conveniently located just 11.3 mi from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Mississippi one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $210. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Knoxville to Mississippi for a low price.

  • What are the most popular routes from Knoxville to Mississippi?

    While some choose either Knoxville McGhee Tyson - Memphis or Knoxville McGhee Tyson - Mobile, Knoxville McGhee Tyson - Baton Rouge Ryan is the most popular route from Knoxville to Mississippi.

  • Can I find deals for flights from Knoxville to Mississippi that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mississippi.

  • Can I find deals for business class flights from Knoxville to Mississippi?

    Yes. Cheapflights offers flight deals from Knoxville to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Mississippi (average of $371). Flying from Knoxville to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Knoxville to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Mississippi

Discover the top 2 airlines that operate flights from Knoxville to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$217Average$320FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$224Average$348FlexibilityNo cancel feeOn-time71%
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