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$144+ Cheap flights from Iowa to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Feb 28 — Mar 71
Fri 2/28
Fri 3/7
1 adult, Economy
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Cheap flight deals from Iowa to Mississippi

Keep the following information in mind while searching for Iowa to Mississippi flight deals. Data was last updated February 23, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(Delta)

One-way from

$144
(American Airlines)

Popular in

March

Cheapest in

December

Average price

$568
Provider with most accurate pricing for Des Moines-Jackson-Evers Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Jackson-Evers Intl flights.
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From Iowa to Mississippi
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One-way flight from Iowa to Mississippi
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Highest demand for flights based on searches. 15% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Iowa to Mississippi

Cheapest flights from Iowa to Mississippi
Explore the most affordable flight options available from Iowa to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2025.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/85:47 amMLI - MEM
1 stop5h 20mDelta
Wed 3/124:51 pmMEM - MLI
1 stop5h 38mDelta
Deal found 2/20$239
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/96:30 pmDSM - MOB
1 stop4h 26mDelta
Sun 7/135:55 amMOB - DSM
1 stop4h 19mDelta
Deal found 2/20$244
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/84:22 pmMLI - MEM
1 stop7h 22mAmerican Airlines
Wed 3/122:47 pmMEM - MLI
2 stops7h 29mAmerican Airlines
Deal found 2/20$244
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/81:59 pmDSM - MOB
1 stop7h 26mAmerican Airlines
Tue 4/155:20 amMOB - DSM
1 stop7h 53mAmerican Airlines
Deal found 2/22$245
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/115:40 pmOMA - MEM
1 stop4h 30mDelta
Wed 3/196:00 amMEM - OMA
1 stop4h 15mDelta
Deal found 2/21$257
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/16:30 amMLI - MOB
2 stops9h 38mUnited Airlines
Sat 4/59:15 amMOB - MLI
2 stops7h 32mUnited Airlines
Deal found 2/22$259
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/911:26 amCID - GPT
2 stops10h 16mAmerican Airlines
Wed 4/1612:42 pmGPT - CID
2 stops9h 38mAmerican Airlines
Deal found 2/22$259
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/151:50 pmOMA - MEM
1 stop6h 19mAmerican Airlines
Tue 4/292:40 pmMEM - OMA
2 stops7h 51mAmerican Airlines
Deal found 2/22$262
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/35:00 amCID - MOB
1 stop6h 50mAmerican Airlines
Mon 3/106:09 pmMOB - CID
1 stop5h 06mAmerican Airlines
Deal found 2/21$284
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/71:50 pmOMA - MOB
1 stop7h 35mAmerican Airlines
Sat 4/1212:46 pmMOB - OMA
2 stops9h 45mAmerican Airlines
Deal found 2/22$289
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/311:30 amCID - MOB
2 stops10h 30mUnited Airlines
Mon 3/1012:50 pmMOB - CID
2 stops8h 46mUnited Airlines
Deal found 2/21$330
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/35:30 amCID - MOB
1 stop6h 32mDelta
Mon 3/105:07 pmMOB - CID
1 stop5h 16mDelta
Deal found 2/21$344

Find flights from Iowa to Mississippi within your budget

Customize your flight search to find flights from Iowa to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.

Fly from

Iowa

Fly to

Mississippi

Route

Depart

Return

Price

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Wed 4/9

5:50 am-10:59 am

1 stop5h 09m

Memphis

Wed 4/16

4:42 pm-10:25 pm

1 stop5h 43m

$199

MolineMemphis

MLI - MEM

MLIMEM

Moline Quad-City

Wed 4/9

11:21 am-8:09 pm

2 stops8h 48m

Memphis

Wed 4/16

12:22 pm-5:58 pm

1 stop5h 36m

$204

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 4/8

1:59 pm-9:25 pm

1 stop7h 26m

Mobile

Tue 4/15

5:20 am-1:13 pm

1 stop7h 53m

$245

Cedar RapidsGulfport

CID - GPT

CIDGPT

Cedar Rapids

Tue 4/1

12:04 pm-10:03 pm

2 stops9h 59m

Gulfport Biloxi Regional

Sat 4/5

4:55 pm-10:19 pm

1 stop5h 24m

$254

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Tue 3/11

5:40 pm-10:10 pm

1 stop4h 30m

Memphis

Wed 3/19

6:00 am-10:15 am

1 stop4h 15m

$257

MolineMobile

MLI - MOB

MLIMOB

Moline Quad-City

Tue 4/1

6:30 am-4:08 pm

2 stops9h 38m

Mobile

Sat 4/5

9:15 am-4:47 pm

2 stops7h 32m

$259

Cedar RapidsGulfport

CID - GPT

CIDGPT

Cedar Rapids

Wed 4/9

11:26 am-9:42 pm

2 stops10h 16m

Gulfport Biloxi Regional

Wed 4/16

12:42 pm-10:20 pm

2 stops9h 38m

$259

OmahaMemphis

OMA - MEM

OMAMEM

Omaha Eppley Airfield

Tue 4/15

1:50 pm-8:09 pm

1 stop6h 19m

Memphis

Tue 4/29

2:40 pm-10:31 pm

2 stops7h 51m

$262

OmahaMobile

OMA - MOB

OMAMOB

Omaha Eppley Airfield

Mon 4/7

1:50 pm-9:25 pm

1 stop7h 35m

Mobile

Sat 4/12

12:46 pm-10:31 pm

2 stops9h 45m

$289

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 3/25

6:30 pm-10:48 pm

1 stop4h 18m

Mobile

Mon 3/31

5:07 pm-10:56 pm

1 stop5h 49m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/22

Showing 1-10 of 37 results
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Best time to book a flight from Iowa to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Iowa to Mississippi

Get recent, data-driven insights about flights from Iowa to Mississippi including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Iowa to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Mississippi by month

Plan your trip to Mississippi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

Temperature in Mississippi by month

Plan your trip to Mississippi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated February 23, 2025.
Read through reviews of airlines operating flights from Iowa to Mississippi, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,396 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,203 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,754 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,396 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Iowa to Mississippi one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $144. Delta flights start at $220 while deals on United Airlines start at $564 one-way.

  • Can I find deals for flights from Iowa to Mississippi that include hotel bookings?

    Yes. In addition to deals on Iowa to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Mississippi.

  • Can I find deals for business class flights from Iowa to Mississippi?

    Yes. Cheapflights offers flight deals from Iowa to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Mississippi (average of $371). Flying from Iowa to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Iowa to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Iowa to Mississippi

Discover the top 2 airlines that operate flights from Iowa to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$330FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$376FlexibilityNo cancel feeOn-time71%
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