HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$214+ Cheap flights from Des Moines (DSM) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — JAN
Feb 4 — Feb 111
Tue 2/4
Tue 2/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Mississippi with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Mississippi

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mississippi (USMS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$232
(United Airlines)

One-way from

$214
(Delta)

Popular in

January

Cheapest in

December

Average price

$639
Provider with most accurate pricing for Des Moines-Jackson-Evers Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Jackson-Evers Intl flights.
Search Deals
From Des Moines to Mississippi
Search Deals
One-way flight from Des Moines to Mississippi
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2025
Search Deals

Find flight deals from Des Moines to Mississippi

Cheapest flights from Des Moines to Mississippi
Explore the most affordable flight options available from Des Moines to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 30, 2025.

This United Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/73:25 pmDSM - MEM
1 stop6h 34mUnited Airlines
Mon 3/108:02 amMEM - DSM
1 stop6h 17mUnited Airlines
Deal found 1/29$232
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/253:23 pmDSM - MEM
2 stops8h 34mAmerican Airlines
Fri 3/287:46 amMEM - DSM
1 stop5h 54mAmerican Airlines
Deal found 1/29$237
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/155:34 amDSM - MEM
1 stop5h 33mDelta
Tue 2/184:11 pmMEM - DSM
1 stop6h 20mDelta
Deal found 1/29$247
This Delta deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/222:14 pmDSM - MOB
1 stop4h 04mDelta
Sat 4/266:00 amMOB - DSM
1 stop4h 16mDelta
Deal found 1/29$279
This Southwest deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/198:30 amDSM - MEM
2 stops11h 30mSouthwest
Mon 2/242:30 pmMEM - DSM
2 stops8h 30mSouthwest
Deal found 1/29$287
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/54:18 pmDSM - MOB
1 stop7h 04mAmerican Airlines
Sat 7/126:07 pmMOB - DSM
1 stop4h 28mAmerican Airlines
Deal found 1/29$294
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/235:45 amDSM - BTR
1 stop7h 38mDelta
Sat 3/296:00 amBTR - DSM
1 stop4h 40mDelta
Deal found 1/30$299
This United deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/56:20 amDSM - MOB
2 stops9h 49mUnited Airlines
Sat 7/124:55 pmMOB - DSM
1 stop5h 35mUnited Airlines
Deal found 1/29$324
This American Airlines deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/15:59 pmDSM - GPT
1 stop5h 22mAmerican Airlines
Mon 2/35:59 pmGPT - DSM
1 stop5h 20mAmerican Airlines
Deal found 1/29$349
This American Airlines deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/185:29 pmDSM - BTR
1 stop5h 17mAmerican Airlines
Mon 4/216:22 pmBTR - DSM
1 stop4h 32mAmerican Airlines
Deal found 1/30$479
This Delta deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/206:30 amDSM - GPT
2 stops10h 45mDelta
Mon 2/246:00 pmGPT - DSM
1 stop4h 31mDelta
Deal found 1/30$524
This Mytrip deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/126:23 pmDSM - GPT
2 stops23h 45mMultiple Airlines
Sun 3/166:48 pmGPT - DSM
2 stops20h 11mMultiple Airlines
Deal found 1/29$541

Find flights from Des Moines to Mississippi within your budget

Customize your flight search to find flights from Des Moines to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Fri 3/7

3:25 pm-9:59 pm

1 stop6h 34m

Memphis

Mon 3/10

8:02 am-2:19 pm

1 stop6h 17m

$232

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Tue 3/25

3:23 pm-11:57 pm

2 stops8h 34m

Memphis

Fri 3/28

7:46 am-1:40 pm

1 stop5h 54m

$237

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Sat 2/15

5:34 am-11:07 am

1 stop5h 33m

Memphis

Tue 2/18

4:11 pm-10:31 pm

1 stop6h 20m

$247

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Tue 4/22

2:14 pm-6:18 pm

1 stop4h 04m

Mobile

Sat 4/26

6:00 am-10:16 am

1 stop4h 16m

$279

Des MoinesMemphis

DSM - MEM

DSMMEM

Des Moines

Wed 2/19

8:30 am-8:00 pm

2 stops11h 30m

Memphis

Mon 2/24

2:30 pm-11:00 pm

2 stops8h 30m

$287

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 7/5

4:18 pm-11:22 pm

1 stop7h 04m

Mobile

Sat 7/12

6:07 pm-10:35 pm

1 stop4h 28m

$294

Des MoinesBaton Rouge

DSM - BTR

DSMBTR

Des Moines

Sun 3/23

5:45 am-1:23 pm

1 stop7h 38m

Baton Rouge Ryan

Sat 3/29

6:00 am-10:40 am

1 stop4h 40m

$299

Des MoinesMobile

DSM - MOB

DSMMOB

Des Moines

Sat 7/5

6:20 am-4:09 pm

2 stops9h 49m

Mobile

Sat 7/12

4:55 pm-10:30 pm

1 stop5h 35m

$324

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Mon 2/24

12:15 pm-10:08 pm

2 stops9h 53m

Gulfport Biloxi Regional

Fri 7/18

6:00 am-1:23 pm

1 stop7h 23m

$354

Des MoinesGulfport

DSM - GPT

DSMGPT

Des Moines

Sun 2/16

6:00 am-5:58 pm

2 stops11h 58m

Gulfport Biloxi Regional

Fri 2/21

6:21 am-7:21 pm

2 stops13h 00m

$437

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/30

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Des Moines to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Mississippi

Get recent, data-driven insights about flights from Des Moines to Mississippi including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mississippi (average of $371). Flying from Des Moines to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MS?

Find hourly flight availability from Des Moines to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mississippi as you normally would.

Rainfall in Mississippi by month

Plan your trip to Mississippi by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mississippi ranges from 2.2 - 5.6 inches per month. December is typically the wettest month, when rainfall can reach 5.6 in. October is typically the driest time to visit Mississippi when rainfall is around 2.2 in.

Temperature in Mississippi by month

Plan your trip to Mississippi by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mississippi, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated January 30, 2025.
To help decide which airline to fly from Des Moines to Mississippi, see what other customers have to say about Southwest, Delta and United Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.1

Entertainment

7.7

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,585 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.1

Entertainment

7.7

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,450 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.1

Entertainment

7.7

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,906 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.1

Entertainment

7.7

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,585 reviews

Boarding

8.2

Crew

8.7

Overall

8.1

Comfort

8.1

Food

7.1

Entertainment

7.7

Reviews

1 / 20

6.0
Good

Lauren,Dec 2024

MCI - DCA

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mississippi?

    If you book a flight to Mississippi from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • What are the cheapest airlines to fly from Des Moines to Mississippi one-way?

    The cheapest airlines for a one-way flight from Des Moines to Mississippi are Delta ($214), American Airlines ($414), and United Airlines ($1,384).

  • What are the most popular routes from Des Moines to Mississippi?

    When deciding which route to take from Des Moines to Mississippi consider Des Moines - Mobile, Des Moines - Memphis or Des Moines - Baton Rouge Ryan as they are the most popular.

  • Can I find deals for flights from Des Moines to Mississippi that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mississippi.

  • Can I find deals for business class flights from Des Moines to Mississippi?

    Yes. Cheapflights offers flight deals from Des Moines to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Mississippi (average of $371). Flying from Des Moines to Mississippi in March is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Sky Harbor Intl flights
Des Moines to Sky Harbor Intl flights
Des Moines to Denver flights
Cedar Rapids to Sky Harbor Intl flights
Cedar Rapids to Denver flights
Omaha to Las Vegas flights
Des Moines to Las Vegas flights
Omaha to Dallas/Fort Worth flights
Omaha to Orlando flights
Des Moines to Orlando flights
Omaha to Seattle flights
Omaha to Denver flights
Omaha to O'Hare Intl flights
Cedar Rapids to Orlando flights
Omaha to Miami flights
Omaha to Hobby flights
Omaha to LaGuardia flights
Cedar Rapids to Miami flights
Des Moines to Miami flights
Des Moines to LaGuardia flights
Des Moines to Seattle flights
Omaha to San Francisco flights
Des Moines to Dallas/Fort Worth flights
Cedar Rapids to Seattle flights
Cedar Rapids to Dallas/Fort Worth flights
Cedar Rapids to Las Vegas flights
Omaha to Los Angeles flights
Omaha to Salt Lake City flights
Moline to Sky Harbor Intl flights
Des Moines to John F Kennedy Intl flights
Des Moines to Atlanta flights
Omaha to Atlanta flights
Omaha to John F Kennedy Intl flights
Omaha to Reagan-National flights
Des Moines to Hobby flights
Omaha to George Bush Intcntl flights
Moline to Orlando flights
Cedar Rapids to Phoenix-Mesa Gateway flights
Des Moines to Reagan-National flights
Des Moines to O'Hare Intl flights
Cedar Rapids to Tampa flights
Des Moines to Tampa flights
Omaha to Newark flights
Des Moines to George Bush Intcntl flights
Omaha to Tampa flights
Cedar Rapids to Fort Myers flights
Cedar Rapids to Atlanta flights
Cedar Rapids to Nashville flights
Des Moines to Dulles Intl flights
Moline to Tampa flights

Top 2 airlines flying from Des Moines to Mississippi

Discover the top 2 airlines that operate flights from Des Moines to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$416FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$362FlexibilityNo cancel feeOn-time71%
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.