What are the cheapest airlines to fly from St. Louis to Mexico one-way?

For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $131. Users have also found prices from $165 and $180 on Delta and Frontier, respectively.

What are the most popular routes from St. Louis to Mexico?

The most popular route from St. Louis to Mexico is Lambert-St Louis - Cancun. You may also consider Lambert-St Louis - Cozumel or Lambert-St Louis - San José del Cabo Los Cabos.

What are the most popular airlines that fly from St. Louis to Mexico?

The most popular airlines flying from St. Louis to Mexico are American Airlines, Aeromexico and Delta. Something to consider prior to booking your flight.

How far in advance should I book a flight from St. Louis to Mexico?

Find a great deal and save up to 56% by booking at least 20 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from St. Louis to Mexico within the next two weeks, with the cheapest ticket starting at $510.

What is the cheapest month to fly from St. Louis to Mexico?

May can be a great time to fly to Mexico from St. Louis with a flight ticket averaging about $629. Cheapflights users have found deals in the month of May for as cheap as $503. The most expensive prices can be found in the month of December.

What airport do you fly from for flights from St. Louis to Mexico?

Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Mexico.

Can I find deals for flights from St. Louis to Mexico that include hotel bookings?

Yes. In addition to deals on St. Louis to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Mexico?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Mexico.

Can I find deals for business class flights from St. Louis to Mexico?

Yes. Cheapflights offers flight deals from St. Louis to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$356+ Flights from St. Louis to Mexico

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Cheap flight deals from St. Louis to Mexico

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$290 (Cheapflightsfares)
One-way from	$120 (Kiwi.com)
Popular in	December
Cheapest in	May
Average price	$596
Good round-trip deal	$407 or less
Good one-way deal	$179 or less

Provider with most accurate pricing for Lambert-St Louis-Mexico City Benito Juarez flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Mexico City Benito Juarez flights.

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From Lambert-St Louis to Mexico

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One-way flight from Lambert-St Louis to Mexico

Search Deals

Highest demand for flights based on searches. 5% potential increase in price ($33 potential increase over avg. RT price).

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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Price to beat on a round-trip flight from Lambert-St Louis to Mexico.

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Price to beat on a one-way flight from Lambert-St Louis to Mexico.

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Find flight deals from St. Louis to Mexico

Cheapest flights from St. Louis to Mexico
Explore the most affordable flight options available from St. Louis to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Thu 6/126:12 pmSTL - CUN

1 stop14h 43mSpirit Airlines

Thu 6/1910:00 amCUN - STL

1 stop7h 04mSpirit Airlines

Deal found 4/22

$290

Sat 5/175:45 pmSTL - CUN

1 stop14h 31mMultiple Airlines

Sat 5/249:12 amCUN - STL

1 stop14h 32mMultiple Airlines

Deal found 4/22

$315

Wed 6/1110:48 amSTL - CUN

2 stops12h 44mAeromexico

Wed 6/1812:39 pmCUN - STL

1 stop8h 01mAeromexico

Deal found 4/22

$344

Wed 5/286:00 amSTL - CUN

1 stop8h 25mDelta

Wed 6/412:30 pmCUN - STL

1 stop8h 19mDelta

Deal found 4/22

$359

Wed 5/78:15 pmSTL - GDL

2 stops29h 10mMultiple Airlines

Sat 5/108:09 amGDL - STL

1 stop14h 57mMultiple Airlines

Deal found 4/22

$366

Mon 5/56:00 amSTL - CUN

1 stop7h 03mFrontier

Sun 5/1112:37 pmCUN - STL

Nonstop3h 23mFrontier

Deal found 4/21

$373

Mon 9/225:15 amSTL - SJD

1 stop8h 55mUnited Airlines

Fri 9/261:46 pmSJD - STL

1 stop6h 14mUnited Airlines

Deal found 4/21

$385

Mon 9/226:00 amSTL - SJD

2 stops12h 01mDelta

Fri 9/266:01 amSJD - STL

2 stops15h 38mDelta

Deal found 4/21

$395

Wed 7/309:25 amSTL - CUN

1 stop7h 40mAmerican Airlines

Sun 8/37:40 amCUN - STL

1 stop11h 51mAmerican Airlines

Deal found 4/22

$404

Tue 5/135:45 pmSTL - MEX

1 stop26h 50mMultiple Airlines

Thu 5/156:00 amMEX - STL

2 stops14h 05mMultiple Airlines

Deal found 4/21

$423

Thu 5/11:30 pmSTL - MEX

1 stop10h 25mAir Canada

Tue 6/107:10 amMEX - STL

1 stop11h 48mAir Canada

Deal found 4/20

$430

Sat 5/38:48 amSTL - CUN

2 stops10h 32mUnited Airlines

Mon 5/53:30 pmCUN - STL

1 stop6h 33mUnited Airlines

Deal found 4/22

$439

Best flights from St. Louis to Mexico
Discover carefully curated flight deals from St. Louis to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2025.

Thu 6/126:12 pmSTL - CUN

1 stop14h 43mSpirit Airlines

Thu 6/1910:00 amCUN - STL

1 stop7h 04mSpirit Airlines

Deal found 4/22

$290

Sat 5/175:45 pmSTL - CUN

1 stop14h 31mMultiple Airlines

Sat 5/249:12 amCUN - STL

1 stop14h 32mMultiple Airlines

Deal found 4/22

$315

Wed 6/1110:48 amSTL - CUN

2 stops12h 44mAeromexico

Wed 6/1812:39 pmCUN - STL

1 stop8h 01mAeromexico

Deal found 4/22

$344

Wed 5/286:00 amSTL - CUN

2 stops12h 42mDelta

Wed 6/48:00 amCUN - STL

1 stop6h 35mDelta

Deal found 4/22

$359

Mon 5/56:00 amSTL - CUN

1 stop7h 03mFrontier

Sun 5/1112:37 pmCUN - STL

Nonstop3h 23mFrontier

Deal found 4/21

$373

Wed 7/309:25 amSTL - CUN

1 stop7h 40mAmerican Airlines

Sun 8/37:40 amCUN - STL

1 stop11h 51mAmerican Airlines

Deal found 4/22

$404

Thu 5/11:30 pmSTL - MEX

1 stop10h 25mAir Canada

Tue 6/107:10 amMEX - STL

1 stop11h 48mAir Canada

Deal found 4/20

$430

Sun 6/18:25 amSTL - CUN

1 stop13h 42mUnited Airlines

Fri 6/65:35 amCUN - STL

1 stop11h 18mUnited Airlines

Deal found 4/22

$449

Tue 6/1011:10 amSTL - CUN

Nonstop3h 10mSouthwest

Tue 6/172:30 pmCUN - STL

Nonstop3h 15mSouthwest

Deal found 4/21

$536

Tue 5/135:45 pmSTL - MEX

1 stop26h 50mMultiple Airlines

Thu 5/156:00 amMEX - STL

2 stops14h 05mMultiple Airlines

Deal found 4/21

$423

Sun 6/81:30 pmSTL - SJD

2 stops10h 07mDelta

Thu 6/126:03 amSJD - STL

2 stops15h 48mDelta

Deal found 4/22

$442

Fri 5/95:19 amSTL - GDL

1 stop18h 36mAmerican Airlines

Mon 5/1211:05 amGDL - STL

1 stop21h 49mAmerican Airlines

Deal found 4/21

$451

Last-minute flights from St. Louis to Mexico
Discover last-minute flight deals from St. Louis to Mexico. Data last updated April 22, 2025 and is based on user searches.

Sun 4/276:00 amSTL - CUN

Nonstop3h 28mVolaris

Sun 5/412:37 pmCUN - STL

Nonstop3h 23mVolaris

Deal found 4/22

$459

Sun 4/276:00 amSTL - PVR

2 stops9h 46mDelta

Wed 6/116:01 amPVR - STL

2 stops14h 33mDelta

Deal found 4/20

$513

Mon 4/286:00 amSTL - CUN

Nonstop3h 28mFrontier

Mon 5/512:37 pmCUN - STL

Nonstop3h 23mFrontier

Deal found 4/20

$415

Mon 4/289:55 pmSTL - GDL

1 stop20h 00mMultiple Airlines

Thu 6/125:10 pmGDL - STL

2 stops29h 43mMultiple Airlines

Deal found 4/20

$452

Tue 4/2910:42 amSTL - PVR

2 stops13h 55mAeromexico

Tue 5/66:02 amPVR - STL

2 stops14h 34mAeromexico

Deal found 4/22

$484

Wed 4/306:00 amSTL - CUN

1 stop7h 03mDelta

Wed 5/149:17 amCUN - STL

2 stops14h 21mDelta

Deal found 4/21

$359

Wed 4/306:18 amSTL - CUN

Nonstop3h 28mMultiple Airlines

Wed 5/1412:18 pmCUN - STL

1 stop20h 57mMultiple Airlines

Deal found 4/21

$396

Thu 5/11:30 pmSTL - MEX

1 stop10h 25mMultiple Airlines

Mon 5/56:45 amMEX - STL

1 stop8h 15mMultiple Airlines

Deal found 4/22

$428

Thu 5/11:30 pmSTL - MEX

1 stop10h 25mAir Canada

Tue 6/107:10 amMEX - STL

1 stop11h 48mAir Canada

Deal found 4/20

$430

Thu 5/16:00 amSTL - MEX

1 stop6h 50mDelta

Mon 5/512:45 pmMEX - STL

2 stops10h 57mDelta

Deal found 4/22

$488

Fri 5/26:53 pmSTL - BJX

2 stops29h 27mMultiple Airlines

Thu 6/126:00 amBJX - STL

1 stop9h 02mMultiple Airlines

Deal found 4/20

$504

Fri 5/26:53 pmSTL - PVR

2 stops27h 07mMultiple Airlines

Wed 6/113:30 pmPVR - STL

2 stops23h 32mMultiple Airlines

Deal found 4/20

$506

One-way flights from St. Louis to Mexico
Search for one-way flight options from St. Louis to Mexico. Find affordable one-way fares based on user searches. Data last updated April 22, 2025.

Sat 5/108:15 pmSTL - BJX

2 stops28h 05mMultiple Airlines

Deal found 4/22

$120

Fri 6/206:12 pmSTL - CUN

1 stop14h 43mSpirit Airlines

Deal found 4/22

$131

Wed 5/148:15 pmSTL - GDL

2 stops26h 05mMultiple Airlines

Deal found 4/22

$131

Wed 5/148:15 pmSTL - MEX

2 stops27h 25mMultiple Airlines

Deal found 4/22

$133

Mon 5/195:45 pmSTL - CUN

1 stop14h 31mMultiple Airlines

Deal found 4/20

$149

Wed 5/148:15 pmSTL - PVR

3 stops42h 06mMultiple Airlines

Deal found 4/22

$155

Wed 5/148:15 pmSTL - MZT

2 stops47h 20mMultiple Airlines

Deal found 4/22

$156

Tue 6/31:09 pmSTL - CUN

2 stops11h 18mDelta

Deal found 4/21

$165

Mon 5/196:10 amSTL - CUN

Nonstop3h 12mFrontier

Deal found 4/21

$180

Wed 5/287:55 pmSTL - SJD

3 stops49h 30mMultiple Airlines

Deal found 4/22

$184

Sat 7/197:38 pmSTL - CUN

1 stop16h 22mAmerican Airlines

Deal found 4/22

$186

Thu 5/11:30 pmSTL - MEX

1 stop10h 25mAir Canada

Deal found 4/20

$195

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Thu 6/12

6:12 pm-8:55 am

1 stop14h 43m

Cancun

Thu 6/19

10:00 am-5:04 pm

1 stop7h 04m

$290

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sat 5/17

5:45 pm-8:16 am

1 stop14h 31m

Cancun

Sat 5/24

9:12 am-11:44 pm

1 stop14h 32m

$315

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 6/11

10:48 am-11:32 pm

2 stops12h 44m

Cancun

Wed 6/18

12:39 pm-8:40 pm

1 stop8h 01m

$344

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 5/28

7:05 am-8:24 pm

2 stops13h 19m

Cancun

Wed 6/4

7:06 am-8:39 pm

2 stops13h 33m

$359

St. LouisGuadalajara

STL - GDL

STLGDL

Lambert-St Louis

Wed 5/7

8:15 pm-12:25 am

2 stops29h 10m

Guadalajara Miguel Hidal

Sat 5/10

8:09 am-12:06 am

1 stop14h 57m

$366

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 5/5

6:00 am-1:03 pm

1 stop7h 03m

Cancun

Sun 5/11

12:37 pm-4:00 pm

Nonstop3h 23m

$373

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sun 5/18

7:19 pm-9:53 am

1 stop14h 34m

Cancun

Sun 5/25

10:35 am-10:19 pm

1 stop11h 44m

$404

St. LouisMexico City

STL - MEX

STLMEX

Lambert-St Louis

Tue 5/13

5:45 pm-7:35 pm

1 stop26h 50m

Mexico City Benito Juarez

Thu 5/15

6:00 am-9:05 pm

2 stops14h 05m

$423

St. LouisMexico City

STL - MEX

STLMEX

Lambert-St Louis

Thu 5/1

1:30 pm-10:55 pm

1 stop10h 25m

Mexico City Benito Juarez

Tue 6/10

7:10 am-7:58 pm

1 stop11h 48m

$430

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sat 5/3

8:48 am-7:20 pm

2 stops10h 32m

Cancun

Mon 5/5

3:30 pm-10:03 pm

1 stop6h 33m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/22

Showing 1-10 of 60 results

...

Best time to book a flight from St. Louis to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Mexico

What is the cheapest month to book a flight from St. Louis to Mexico?

Currently, May is the cheapest month in which you can book a flight from St. Louis to Mexico (average of $400). Flying from St. Louis to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to MX?

When flying from St. Louis to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mexico by month

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Read reviews from past customers who have flown Delta, Alaska Airlines and Southwest from St. Louis to Mexico. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,920 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Alaska Airlines

8.0

Very good

9,906 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Southwest

8.0

Very good

4,286 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Aeromexico

7.5

Good

1,700 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,684 reviews

Delta

8.0

Very good

7,920 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from St. Louis to Mexico?
Lambert-St Louis (STL), located 12.7 mi from the city center, is the airport you fly out of when you book flights from St. Louis to Mexico.
What are the cheapest airlines to fly from St. Louis to Mexico one-way?
For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $131. Users have also found prices from $165 and $180 on Delta and Frontier, respectively.
What are the most popular routes from St. Louis to Mexico?
The most popular route from St. Louis to Mexico is Lambert-St Louis - Cancun. You may also consider Lambert-St Louis - Cozumel or Lambert-St Louis - San José del Cabo Los Cabos.
Can I find deals for flights from St. Louis to Mexico that include hotel bookings?
Yes. In addition to deals on St. Louis to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Mexico?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Mexico.
Can I find deals for business class flights from St. Louis to Mexico?
Yes. Cheapflights offers flight deals from St. Louis to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Mexico?
Currently, May is the cheapest month in which you can book a flight from St. Louis to Mexico (average of $400). Flying from St. Louis to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 8 airlines flying from St. Louis to Mexico

Airline	Cheapest	Average	Flexibility	On-time
Volaris	Cheapest$175	Average$378	FlexibilityNo cancel fee	On-time79%
Frontier	Cheapest$302	Average$554	FlexibilityNo cancel fee	On-time62%
Aeromexico	Cheapest$331	Average$509	FlexibilityNo cancel fee	On-timeN/A
Delta	Cheapest$358	Average$545	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$387	Average$613	FlexibilityNo cancel fee	On-time69%
Alaska Airlines	Cheapest$398	Average$528	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$401	Average$586	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$518	Average$739	FlexibilityNo cancel fee	On-time63%

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$120+ Cheap flights from St. Louis (STL) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Mexico with Cheapflights

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Cheap flight deals from St. Louis to Mexico

Keep the following information in mind while searching for St. Louis to Mexico flight deals. Data was last updated April 22, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from St. Louis to Mexico

Cheapest flights from St. Louis to MexicoExplore the most affordable flight options available from St. Louis to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Explore the most affordable flight options available from St. Louis to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Mexico that are best for you.

Best time to book a flight from St. Louis to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Mexico

What is the cheapest month to book a flight from St. Louis to Mexico?

What is the cheapest time of day to fly from STL to MX?

Find hourly flight availability from St. Louis to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 22, 2025.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

Reviews of airlines servicing Mexico

Read reviews from past customers who have flown Delta, Alaska Airlines and Southwest from St. Louis to Mexico. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from St. Louis to Mexico?

What are the cheapest airlines to fly from St. Louis to Mexico one-way?

What are the most popular routes from St. Louis to Mexico?

Can I find deals for flights from St. Louis to Mexico that include hotel bookings?

How can I find direct flights from St. Louis to Mexico?

Can I find deals for business class flights from St. Louis to Mexico?

What is the cheapest month to book a flight from St. Louis to Mexico?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Mexico

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from St. Louis to Mexico

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Cheapest flights from St. Louis to Mexico
Explore the most affordable flight options available from St. Louis to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2025.