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$196+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico

Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$338
(Mytrip)

One-way from

$196
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$672
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico
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One-way flight from Knoxville McGhee Tyson to Mexico
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Highest demand for flights based on searches. 12% potential increase in price ($102 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:43 pmTYS - CUN
2 stops19h 33mMultiple Airlines
Tue 5/1312:18 pmCUN - TYS
1 stop26h 54mMultiple Airlines
Deal found 3/27$338
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/25:37 pmTYS - MEX
1 stop13h 13mMultiple Airlines
Sun 6/811:05 amMEX - TYS
1 stop10h 31mMultiple Airlines
Deal found 3/26$414
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/111:29 pmTYS - MTY
2 stops34h 16mMultiple Airlines
Thu 4/171:50 pmMTY - TYS
2 stops26h 09mMultiple Airlines
Deal found 3/27$429
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:45 amTYS - GDL
2 stops11h 43mDelta
Tue 5/201:00 pmGDL - TYS
1 stop8h 51mDelta
Deal found 3/27$437
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/56:55 pmTYS - CUN
1 stop15h 20mAmerican Airlines
Fri 7/1112:45 pmCUN - TYS
1 stop10h 19mAmerican Airlines
Deal found 3/27$464
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/35:30 amTYS - CUN
1 stop5h 30mDelta
Thu 8/712:30 pmCUN - TYS
2 stops10h 17mDelta
Deal found 3/26$468
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/117:00 amTYS - MTY
1 stop6h 31mDelta
Thu 4/1712:26 pmMTY - TYS
1 stop9h 22mDelta
Deal found 3/27$472
This Aeromexico deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1012:01 pmTYS - CUN
2 stops12h 26mAeromexico
Wed 6/1812:42 pmCUN - TYS
1 stop7h 34mAeromexico
Deal found 3/26$481
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/152:56 pmTYS - GDL
1 stop9h 59mAmerican Airlines
Tue 5/206:00 amGDL - TYS
1 stop15h 58mAmerican Airlines
Deal found 3/27$486
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/105:45 amTYS - MEX
1 stop6h 30mDelta
Wed 4/163:30 pmMEX - TYS
1 stop6h 18mDelta
Deal found 3/27$487
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/197:54 pmTYS - MEX
1 stop17h 41mAmerican Airlines
Fri 5/231:10 pmMEX - TYS
1 stop8h 48mAmerican Airlines
Deal found 3/27$511
This Mytrip deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/156:30 amTYS - GDL
3 stops36h 58mMultiple Airlines
Tue 5/207:07 amGDL - TYS
2 stops30h 20mMultiple Airlines
Deal found 3/27$515

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.

Fly from

Knoxville

Fly to

Mexico

Route

Depart

Return

Price

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Thu 5/8

1:43 pm-8:16 am

2 stops19h 33m

Cancun

Tue 5/13

12:18 pm-4:12 pm

1 stop26h 54m

$338

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 6/2

5:37 pm-4:50 am

1 stop13h 13m

Mexico City Benito Juarez

Sun 6/8

11:05 am-11:36 pm

1 stop10h 31m

$414

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Fri 4/11

1:29 pm-9:45 pm

2 stops34h 16m

Monterrey Gen Mariano Escobedo

Thu 4/17

1:50 pm-5:59 pm

2 stops26h 09m

$429

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/15

5:45 am-3:28 pm

2 stops11h 43m

Guadalajara Miguel Hidal

Tue 5/20

1:00 pm-11:51 pm

1 stop8h 51m

$437

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sat 7/5

6:55 pm-9:15 am

1 stop15h 20m

Cancun

Fri 7/11

12:45 pm-12:04 am

1 stop10h 19m

$464

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 8/3

5:30 am-10:00 am

1 stop5h 30m

Cancun

Thu 8/7

12:30 pm-11:47 pm

2 stops10h 17m

$468

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Fri 4/11

7:00 am-11:31 am

1 stop6h 31m

Monterrey Gen Mariano Escobedo

Thu 4/17

12:26 pm-11:48 pm

1 stop9h 22m

$472

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 6/10

12:01 pm-11:27 pm

2 stops12h 26m

Cancun

Wed 6/18

12:42 pm-9:16 pm

1 stop7h 34m

$481

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/15

2:56 pm-10:55 pm

1 stop9h 59m

Guadalajara Miguel Hidal

Tue 5/20

6:00 am-11:58 pm

1 stop15h 58m

$486

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 4/10

5:45 am-10:15 am

1 stop6h 30m

Mexico City Benito Juarez

Wed 4/16

3:30 pm-11:48 pm

1 stop6h 18m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 30 results
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mexico

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $400). Flying from Knoxville to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MX?

Find hourly flight availability from Knoxville to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

When flying from Knoxville to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated March 28, 2025.
See what other customers who have flown with Delta, Aeromexico and United Airlines from Knoxville to Mexico have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,896 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Aeromexico
7.5
Good
1,701 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,603 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
WestJet
7.2
Good
2,785 reviews
Delta
8.0
Very good
7,896 reviews

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Comfort

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the most popular routes from Knoxville to Mexico?

    The most popular route from Knoxville to Mexico is Knoxville McGhee Tyson - Cancun. You may also consider Knoxville McGhee Tyson - Cozumel or Knoxville McGhee Tyson - Mexico City Benito Juarez.

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $400). Flying from Knoxville to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$442Average$550FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$447Average$716FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$447Average$644FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$467Average$654FlexibilityNo cancel feeOn-time71%
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