$228+ Cheap flights from Knoxville (TYS) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from Knoxville to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Mexico
Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated April 17, 2025.
Most accurate provider | AranGrant 3 stars |
|---|---|
Most trusted provider | AranGrant 3 stars |
Round-trip from | $473 (American Airlines) |
One-way from | $228 (American Airlines) |
Popular in | December |
Cheapest in | April |
Average price | $487 |
Find flight deals from Knoxville to Mexico
Cheapest flights from Knoxville to MexicoExplore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This SmartFares deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Knoxville to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
KnoxvilleCancún
TYS - CUN
TYSCUN
Knoxville McGhee Tyson
Sat 7/12
8:22 pm-9:40 am
1 stop14h 18m
Cancun
Thu 7/17
4:25 pm-8:34 am
1 stop15h 09m
KnoxvilleCancún
TYS - CUN
TYSCUN
Knoxville McGhee Tyson
Sun 6/29
9:08 pm-11:26 am
1 stop15h 18m
Cancun
Sun 7/6
12:23 pm-4:47 pm
3 stops27h 24m
KnoxvilleCancún
TYS - CUN
TYSCUN
Knoxville McGhee Tyson
Tue 6/10
5:45 am-11:25 am
1 stop6h 40m
Cancun
Wed 6/18
9:55 am-5:12 pm
1 stop6h 17m
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Fri 5/30
9:03 pm-5:55 pm
2 stops22h 52m
Mexico City Benito Juarez
Mon 6/23
11:15 pm-4:08 pm
2 stops14h 53m
KnoxvilleGuadalajara
TYS - GDL
TYSGDL
Knoxville McGhee Tyson
Tue 6/17
2:32 pm-10:34 pm
2 stops10h 02m
Guadalajara Miguel Hidal
Fri 6/20
12:17 pm-11:59 pm
2 stops9h 42m
KnoxvilleMexico City
TYS - MEX
TYSMEX
Knoxville McGhee Tyson
Fri 5/30
12:08 pm-6:40 pm
1 stop8h 32m
Mexico City Benito Juarez
Mon 6/23
3:30 pm-11:59 pm
1 stop6h 29m
KnoxvilleGuadalajara
TYS - GDL
TYSGDL
Knoxville McGhee Tyson
Tue 6/17
6:25 pm-10:18 pm
1 stop5h 53m
Guadalajara Miguel Hidal
Fri 6/20
10:48 am-11:59 pm
1 stop11h 11m
KnoxvilleSan José del Cabo
TYS - SJD
TYSSJD
Knoxville McGhee Tyson
Fri 9/26
5:30 am-11:30 am
1 stop9h 00m
San José del Cabo Los Cabos
Tue 9/30
10:54 am-11:46 pm
2 stops9h 52m
KnoxvillePuerto Vallarta
TYS - PVR
TYSPVR
Knoxville McGhee Tyson
Fri 8/8
7:35 pm-11:14 am
2 stops17h 39m
Puerto Vallarta Ordaz
Fri 8/15
2:56 pm-11:44 pm
1 stop6h 48m
KnoxvilleSan José del Cabo
TYS - SJD
TYSSJD
Knoxville McGhee Tyson
Sat 5/31
6:28 pm-8:15 am
1 stop16h 47m
San José del Cabo Los Cabos
Sat 6/7
8:55 am-11:59 pm
1 stop12h 04m
Best time to book a flight from Knoxville to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Mexico
What is the cheapest month to book a flight from Knoxville to Mexico?
Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $400). Flying from Knoxville to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to MX?
Find hourly flight availability from Knoxville to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.
When flying from Knoxville to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in Mexico by month
Plan your trip to Mexico by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.
Temperature in Mexico by month
Plan your trip to Mexico by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated April 17, 2025.
See what other customers who have flown with Delta, LATAM Airlines and Aeromexico from Knoxville to Mexico have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Food
Comfort
Entertainment
Boarding
Overall
Crew
Reviews
Aaron,Oct 2024
LAX - LHR
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Knoxville to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from Knoxville to Mexico
Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$442 | Average$667 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$447 | Average$701 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$447 | Average$642 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$467 | Average$638 | FlexibilityNo cancel fee | On-time71% |