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$265+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Feb 27 — Mar 61
Thu 2/27
Thu 3/6
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico

Keep the following information in mind while searching for Knoxville to Mexico flight deals. Data was last updated February 22, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$400
(Kiwi.com)

One-way from

$265
(Aeromexico)

Popular in

February

Cheapest in

April

Average price

$1,089
Provider with most accurate pricing for Knoxville McGhee Tyson-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Mexico City Benito Juarez flights.
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From Knoxville McGhee Tyson to Mexico
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One-way flight from Knoxville McGhee Tyson to Mexico
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Highest demand for flights based on searches. 17% potential increase in price ($163 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2025.

This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/21:25 pmTYS - MEX
1 stop8h 10mMultiple Airlines
Tue 4/811:05 amMEX - TYS
1 stop28h 50mMultiple Airlines
Deal found 2/21$400
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/189:59 pmTYS - CUN
1 stop11h 14mMultiple Airlines
Wed 3/1912:25 pmCUN - TYS
1 stop6h 27mMultiple Airlines
Deal found 2/21$419
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/266:45 amTYS - CUN
2 stops11h 56mDelta
Fri 8/2912:42 pmCUN - TYS
2 stops10h 05mDelta
Deal found 2/21$449
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:08 amTYS - CUN
1 stop14h 07mAmerican Airlines
Wed 10/82:24 pmCUN - TYS
1 stop7h 48mAmerican Airlines
Deal found 2/21$474
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/257:00 amTYS - CZM
1 stop8h 00mDelta
Tue 4/12:20 pmCZM - TYS
1 stop5h 21mDelta
Deal found 2/20$491
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/712:00 pmTYS - GDL
2 stops12h 36mDelta
Wed 5/2110:08 amGDL - TYS
2 stops11h 38mDelta
Deal found 2/21$495
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/16:18 pmTYS - GDL
1 stop6h 26mAmerican Airlines
Mon 5/56:00 amGDL - TYS
2 stops13h 07mAmerican Airlines
Deal found 2/21$500
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:37 pmTYS - SJD
2 stops19h 32mMultiple Airlines
Thu 6/53:32 pmSJD - TYS
2 stops22h 46mMultiple Airlines
Deal found 2/19$515
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/298:45 amTYS - SJD
1 stop7h 20mDelta
Tue 5/610:54 amSJD - TYS
2 stops9h 54mDelta
Deal found 2/20$516
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/77:00 amTYS - CZM
1 stop7h 19mUnited Airlines
Mon 4/141:21 pmCZM - TYS
2 stops18h 54mUnited Airlines
Deal found 2/21$520
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/106:28 pmTYS - CZM
1 stop20h 32mAmerican Airlines
Sat 5/174:15 pmCZM - TYS
1 stop5h 44mAmerican Airlines
Deal found 2/20$525
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/315:45 amTYS - CZM
1 stop9h 15mAeromexico
Wed 4/22:20 pmCZM - TYS
1 stop7h 22mAeromexico
Deal found 2/20$543

Find flights from Knoxville to Mexico within your budget

Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.

Fly from

Knoxville

Fly to

Mexico

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 4/2

1:25 pm-7:35 pm

1 stop8h 10m

Mexico City Benito Juarez

Tue 4/8

11:05 am-5:55 pm

1 stop28h 50m

$400

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 3/18

9:59 pm-8:13 am

1 stop11h 14m

Cancun

Wed 3/19

12:25 pm-7:52 pm

1 stop6h 27m

$419

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Wed 4/9

2:35 pm-11:55 pm

2 stops10h 20m

Cancun

Wed 4/16

2:03 pm-10:59 pm

1 stop7h 56m

$480

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Tue 3/25

7:00 am-1:00 pm

1 stop8h 00m

Cozumel

Tue 4/1

2:20 pm-9:41 pm

1 stop5h 21m

$491

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Wed 5/7

12:00 pm-10:36 pm

2 stops12h 36m

Guadalajara Miguel Hidal

Wed 5/21

10:08 am-11:46 pm

2 stops11h 38m

$495

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 5/1

6:18 pm-10:44 pm

1 stop6h 26m

Guadalajara Miguel Hidal

Mon 5/5

6:00 am-9:07 pm

2 stops13h 07m

$500

KnoxvilleSan José del Cabo

TYS - SJD

TYSSJD

Knoxville McGhee Tyson

Fri 5/30

5:37 pm-10:09 am

2 stops19h 32m

San José del Cabo Los Cabos

Thu 6/5

3:32 pm-5:18 pm

2 stops22h 46m

$515

KnoxvilleSan José del Cabo

TYS - SJD

TYSSJD

Knoxville McGhee Tyson

Tue 4/29

5:30 am-11:10 am

1 stop8h 40m

San José del Cabo Los Cabos

Tue 5/6

2:10 pm-11:48 pm

1 stop6h 38m

$516

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 5/18

7:55 pm-9:34 am

1 stop14h 39m

Cancun

Fri 5/23

10:40 am-11:54 pm

1 stop12h 14m

$518

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Mon 4/7

7:00 am-12:19 pm

1 stop7h 19m

Cozumel

Mon 4/14

1:21 pm-10:15 am

2 stops18h 54m

$520

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 33 results
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Mexico

Get recent, data-driven insights about flights from Knoxville to Mexico including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $400). Flying from Knoxville to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MX?

Find hourly flight availability from Knoxville to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2025.

When flying from Knoxville to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated February 22, 2025.
See what other customers who have flown with Delta, LATAM Airlines and Aeromexico from Knoxville to Mexico have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,213 reviews
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,793 reviews
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Aeromexico
7.5
Good
1,769 reviews
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,759 reviews
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,213 reviews

Overall

8.0

Boarding

8.2

Entertainment

7.9

Comfort

8.0

Crew

8.5

Food

7.3

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the cheapest airlines to fly from Knoxville to Mexico one-way?

    $265 is the cheapest one-way deal found within the past few days, from Aeromexico. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $296 and $340, respectively.

  • What are the most popular routes from Knoxville to Mexico?

    The most popular route from Knoxville to Mexico is Knoxville McGhee Tyson - Cancun. You may also consider Knoxville McGhee Tyson - Cozumel or Knoxville McGhee Tyson - San José del Cabo Los Cabos.

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $400). Flying from Knoxville to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$443Average$855FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$446Average$723FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$447Average$661FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$466Average$666FlexibilityNo cancel feeOn-time71%
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