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$321+ Cheap flights from Knoxville (TYS) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CUN
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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Cheap flight deals from Knoxville to Mexico

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico (MX0). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$381
(Kiwi.com)

One-way from

$321
(American Airlines)
From Knoxville McGhee Tyson to Mexico
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One-way flight from Knoxville McGhee Tyson to Mexico
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Find flight deals from Knoxville to Mexico

Cheapest flights from Knoxville to Mexico
Explore the most affordable flight options available from Knoxville to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/29:16 pmTYS - CUN
1 stop14h 55mMultiple Airlines
Sat 3/810:16 amCUN - TYS
1 stop10h 49mMultiple Airlines
Deal found 1/19$381
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/59:20 amTYS - MEX
1 stop13h 45mMultiple Airlines
Wed 3/126:55 amMEX - TYS
2 stops10h 57mMultiple Airlines
Deal found 1/20$425
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/244:00 pmTYS - CUN
1 stop4h 53mDelta
Fri 6/278:10 amCUN - TYS
1 stop9h 07mDelta
Deal found 1/20$440
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/205:28 amTYS - GDL
1 stop19h 21mAmerican Airlines
Thu 2/276:00 amGDL - TYS
1 stop7h 55mAmerican Airlines
Deal found 1/20$444
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/46:08 amTYS - CUN
1 stop14h 07mAmerican Airlines
Fri 10/1010:35 amCUN - TYS
1 stop6h 05mAmerican Airlines
Deal found 1/20$465
This Aeromexico deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/115:45 amTYS - CUN
1 stop5h 20mAeromexico
Tue 3/184:40 pmCUN - TYS
1 stop6h 02mAeromexico
Deal found 1/20$474
This Aeromexico deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/115:45 amTYS - CZM
1 stop9h 15mAeromexico
Tue 3/182:20 pmCZM - TYS
1 stop7h 22mAeromexico
Deal found 1/20$484
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/35:45 amTYS - GDL
1 stop8h 10mDelta
Mon 3/107:58 amGDL - TYS
2 stops13h 44mDelta
Deal found 1/20$488
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/65:51 amTYS - MTY
1 stop17h 24mAmerican Airlines
Thu 3/132:25 pmMTY - TYS
1 stop7h 33mAmerican Airlines
Deal found 1/20$495
This Mytrip deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/111:57 amTYS - MTY
3 stops22h 19mMultiple Airlines
Sat 2/89:00 amMTY - TYS
1 stop8h 16mMultiple Airlines
Deal found 1/20$501
This Kiwi.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:00 amTYS - GDL
2 stops13h 22mMultiple Airlines
Fri 3/710:15 amGDL - TYS
1 stop10h 37mMultiple Airlines
Deal found 1/20$511
This Trip.com deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/512:08 pmTYS - MEX
1 stop8h 47mAeromexico
Wed 3/1211:30 amMEX - TYS
1 stop6h 30mAeromexico
Deal found 1/20$526

Find flights from Knoxville to Mexico within your budget

Customize your flight search to find flights from Knoxville to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

Fly from

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Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 3/2

9:16 pm-12:11 pm

1 stop14h 55m

Cancun

Sat 3/8

10:16 am-9:05 pm

1 stop10h 49m

$381

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 3/5

9:20 am-10:05 pm

1 stop13h 45m

Mexico City Benito Juarez

Wed 3/12

6:55 am-7:52 pm

2 stops10h 57m

$425

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sun 5/4

5:30 am-9:59 am

1 stop5h 29m

Cancun

Wed 5/7

8:10 am-3:06 pm

1 stop5h 56m

$440

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Thu 2/20

5:28 am-11:49 pm

1 stop19h 21m

Guadalajara Miguel Hidal

Thu 2/27

6:00 am-2:55 pm

1 stop7h 55m

$444

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Tue 3/11

5:45 am-6:40 pm

2 stops13h 55m

Cancun

Tue 3/18

4:40 pm-11:42 pm

1 stop6h 02m

$474

KnoxvilleCancún

TYS - CUN

TYSCUN

Knoxville McGhee Tyson

Sat 3/1

7:58 pm-10:25 am

1 stop14h 27m

Cancun

Wed 3/5

1:10 pm-7:10 pm

1 stop6h 00m

$481

KnoxvilleCozumel

TYS - CZM

TYSCZM

Knoxville McGhee Tyson

Tue 3/11

5:45 am-1:00 pm

1 stop9h 15m

Cozumel

Tue 3/18

2:20 pm-11:42 pm

1 stop7h 22m

$484

KnoxvilleGuadalajara

TYS - GDL

TYSGDL

Knoxville McGhee Tyson

Mon 3/3

5:45 am-5:32 pm

2 stops12h 47m

Guadalajara Miguel Hidal

Mon 3/10

9:28 am-11:42 pm

2 stops12h 14m

$488

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Thu 3/6

5:51 am-10:15 pm

1 stop17h 24m

Monterrey Gen Mariano Escobedo

Thu 3/13

2:25 pm-11:58 pm

1 stop7h 33m

$495

KnoxvilleMonterrey

TYS - MTY

TYSMTY

Knoxville McGhee Tyson

Sat 2/1

11:57 am-9:16 am

3 stops22h 19m

Monterrey Gen Mariano Escobedo

Sat 2/8

9:00 am-6:16 pm

1 stop8h 16m

$501

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/19

Showing 1-10 of 30 results
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Best time to book a flight from Knoxville to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Mexico

Get recent, data-driven insights about flights from Knoxville to Mexico including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Mexico?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $360). Flying from Knoxville to Mexico in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MX?

Find hourly flight availability from Knoxville to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

When flying from Knoxville to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated January 21, 2025.
See what other customers who have flown with Delta, Aeromexico and American Airlines from Knoxville to Mexico have to say. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,521 reviews
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Aeromexico
7.5
Good
1,849 reviews
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

WestJet
7.2
Good
2,828 reviews
Delta
8.0
Very good
8,521 reviews

Crew

8.6

Food

7.3

Overall

8.0

Comfort

8.0

Entertainment

7.9

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • What are the most popular routes from Knoxville to Mexico?

    The most popular route from Knoxville to Mexico is Knoxville McGhee Tyson - Cancun. You may also consider Knoxville McGhee Tyson - Cozumel or Knoxville McGhee Tyson - San José del Cabo Los Cabos.

  • Can I find deals for flights from Knoxville to Mexico that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico.

  • Can I find deals for business class flights from Knoxville to Mexico?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Mexico (average of $360). Flying from Knoxville to Mexico in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Knoxville to Mexico

Discover the top 4 airlines that operate flights from Knoxville to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$417Average$746FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$424Average$647FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$441Average$943FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$466Average$664FlexibilityNo cancel feeOn-time69%
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