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$155+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/21. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated March 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$337
(Kiwi.com)

One-way from

$155
(Mytrip)

Popular in

December

Cheapest in

February

Average price

$674
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
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From Des Moines to Mexico
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One-way flight from Des Moines to Mexico
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Highest demand for flights based on searches. 7% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/131:27 pmDSM - MTY
1 stop9h 18mMultiple Airlines
Sat 4/197:35 pmMTY - DSM
1 stop22h 19mMultiple Airlines
Deal found 3/27$337
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/11:27 pmDSM - MEX
1 stop9h 33mMultiple Airlines
Wed 5/73:45 pmMEX - DSM
1 stop26h 09mMultiple Airlines
Deal found 3/27$359
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/115:27 pmDSM - MTY
1 stop18h 22mAmerican Airlines
Sun 5/185:00 amMTY - DSM
1 stop10h 37mAmerican Airlines
Deal found 3/27$429
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/111:12 pmDSM - BJX
1 stop21h 33mAmerican Airlines
Sun 5/185:08 amBJX - DSM
1 stop6h 13mAmerican Airlines
Deal found 3/27$450
This SmartFares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:35 amDSM - MTY
1 stop6h 37mAeromexico
Sat 5/177:25 amMTY - DSM
2 stops14h 05mAeromexico
Deal found 3/26$450
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:15 amDSM - GDL
1 stop10h 13mAmerican Airlines
Sat 5/176:00 amGDL - DSM
1 stop9h 37mAmerican Airlines
Deal found 3/27$461
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/147:01 amDSM - BJX
2 stops10h 28mDelta
Thu 5/297:37 amBJX - DSM
2 stops13h 53mDelta
Deal found 3/27$469
This Delta deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/147:01 amDSM - GDL
2 stops11h 34mDelta
Thu 5/299:22 amGDL - DSM
2 stops12h 08mDelta
Deal found 3/27$469
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:01 amDSM - CUN
2 stops10h 27mDelta
Wed 5/1412:30 pmCUN - DSM
1 stop8h 16mDelta
Deal found 3/26$475
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/192:25 pmDSM - GDL
1 stop11h 30mMultiple Airlines
Thu 5/298:38 amGDL - DSM
1 stop11h 53mMultiple Airlines
Deal found 3/27$476
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/105:35 amDSM - MTY
1 stop6h 37mDelta
Sat 5/1712:22 pmMTY - DSM
1 stop9h 08mDelta
Deal found 3/26$476
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/96:45 amDSM - CUN
1 stop6h 55mAmerican Airlines
Fri 5/167:50 amCUN - DSM
1 stop8h 47mAmerican Airlines
Deal found 3/27$476

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Des Moines to Mexico that are best for you.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Sun 4/13

1:27 pm-9:45 pm

1 stop9h 18m

Monterrey Gen Mariano Escobedo

Sat 4/19

7:35 pm-6:54 pm

1 stop22h 19m

$337

Des MoinesMexico City

DSM - MEX

DSMMEX

Des Moines

Thu 5/1

1:27 pm-10:00 pm

1 stop9h 33m

Mexico City Benito Juarez

Wed 5/7

3:45 pm-6:54 pm

1 stop26h 09m

$359

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Sun 5/11

5:27 pm-10:49 am

1 stop18h 22m

Monterrey Gen Mariano Escobedo

Sun 5/18

5:00 am-4:37 pm

1 stop10h 37m

$429

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

Sat 5/10

5:35 am-11:12 am

1 stop6h 37m

Monterrey Gen Mariano Escobedo

Sat 5/17

7:25 am-10:30 pm

2 stops14h 05m

$450

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Sun 5/11

1:12 pm-9:45 am

1 stop21h 33m

León Del Bajio

Sun 5/18

5:08 am-12:21 pm

1 stop6h 13m

$450

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sat 5/10

5:15 am-2:28 pm

1 stop10h 13m

Guadalajara Miguel Hidal

Sat 5/17

6:00 am-4:37 pm

1 stop9h 37m

$461

Des MoinesLeón

DSM - BJX

DSMBJX

Des Moines

Wed 5/14

7:01 am-4:29 pm

2 stops10h 28m

León Del Bajio

Thu 5/29

7:37 am-10:30 pm

2 stops13h 53m

$469

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Wed 5/14

7:01 am-5:35 pm

2 stops11h 34m

Guadalajara Miguel Hidal

Thu 5/29

9:22 am-10:30 pm

2 stops12h 08m

$469

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

Fri 5/9

7:01 am-5:28 pm

2 stops10h 27m

Cancun

Wed 5/14

12:30 pm-8:46 pm

1 stop8h 16m

$475

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 5/19

2:25 pm-12:55 am

1 stop11h 30m

Guadalajara Miguel Hidal

Thu 5/29

8:38 am-9:31 pm

1 stop11h 53m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/28

Showing 1-10 of 44 results
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mexico

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico as you normally would.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated March 28, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and Aeromexico from Des Moines to Mexico to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,273 reviews
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,896 reviews
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Aeromexico
7.5
Good
1,701 reviews
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,603 reviews
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,273 reviews

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Comfort

8.1

Overall

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $233. Users have also found prices from $256 and $278 on Delta and United Airlines, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - Mexico City Benito Juarez when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$350Average$507FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$402Average$575FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$421Average$684FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$616FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$460Average$633FlexibilityNo cancel feeOn-time63%
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