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$155+ Cheap flights from Des Moines (DSM) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MEX
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from Des Moines to Mexico

Keep the following information in mind while searching for Des Moines to Mexico flight deals. Data was last updated febrero 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$382
(American Airlines)

One-way from

$155
(Expedia)

Popular in

December

Cheapest in

April

Average price

$655
Provider with most accurate pricing for Des Moines-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Mexico City Benito Juarez flights.
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From Des Moines to Mexico
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One-way flight from Des Moines to Mexico
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Highest demand for flights based on searches. 7% potential increase in price ($56 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Des Moines to Mexico

Cheapest flights from Des Moines to Mexico
Explore the most affordable flight options available from Des Moines to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/92:44 pmDSM - TIJ
1 stop22h 47mAmerican Airlines
vie. 5/2312:12 pmTIJ - DSM
1 stop23h 08mAmerican Airlines
Deal found 2/19$382
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 4/35:29 pmDSM - SJD
1 stop21h 09mAmerican Airlines
jue. 4/102:29 pmSJD - DSM
1 stop19h 38mAmerican Airlines
Deal found 2/19$447
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 3/23:24 pmDSM - GDL
2 stops31h 19mMultiple Airlines
mié. 3/1210:15 amGDL - DSM
2 stops27h 25mMultiple Airlines
Deal found 2/20$448
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 4/46:38 pmDSM - CZM
1 stop21h 12mAmerican Airlines
vie. 4/111:55 pmCZM - DSM
1 stop21h 12mAmerican Airlines
Deal found 2/19$475
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/296:30 pmDSM - CUN
2 stops13h 25mDelta
mié. 12/38:10 amCUN - DSM
1 stop6h 13mDelta
Deal found 2/20$485
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/71:32 pmDSM - CUN
2 stops20h 32mMultiple Airlines
lun. 3/109:08 amCUN - DSM
2 stops14h 07mMultiple Airlines
Deal found 2/20$487
This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/15:45 amDSM - CZM
1 stop8h 15mAeromexico
mar. 4/82:20 pmCZM - DSM
1 stop7h 39mAeromexico
Deal found 2/19$491
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/185:29 pmDSM - GDL
1 stop17h 59mAmerican Airlines
mar. 3/256:30 amGDL - DSM
2 stops16h 21mAmerican Airlines
Deal found 2/20$492
This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/265:45 amDSM - MTY
1 stop6h 51mAeromexico
mar. 6/312:25 pmMTY - DSM
1 stop7h 20mAeromexico
Deal found 2/19$503
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/295:45 amDSM - CUN
2 stops11h 49mAeromexico
sáb. 4/512:40 pmCUN - DSM
1 stop10h 19mAeromexico
Deal found 2/20$513
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/85:00 amDSM - CUN
1 stop14h 48mAmerican Airlines
jue. 3/132:51 pmCUN - DSM
1 stop7h 07mAmerican Airlines
Deal found 2/20$515
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/277:00 amDSM - SJD
2 stops13h 17mDelta
vie. 5/212:15 pmSJD - DSM
1 stop8h 32mDelta
Deal found 2/19$520

Find flights from Des Moines to Mexico within your budget

Customize your flight search to find flights from Des Moines to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

Des Moines

Fly to

Mexico

Route

Depart

Return

Price

Des MoinesTijuana

DSM - TIJ

DSMTIJ

Des Moines

vie. 5/9

2:44 pm-11:31 am

1 stop22h 47m

Tijuana Rodriguez

vie. 5/23

12:12 pm-1:20 pm

1 stop23h 08m

$382

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

dom. 3/2

3:24 pm-10:43 pm

2 stops31h 19m

Guadalajara Miguel Hidal

mié. 3/12

6:02 am-12:51 pm

2 stops29h 49m

$439

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

jue. 4/3

5:29 pm-12:38 pm

1 stop21h 09m

San José del Cabo Los Cabos

jue. 4/10

2:29 pm-12:07 pm

1 stop19h 38m

$447

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

mar. 4/1

6:52 am-8:00 pm

2 stops13h 08m

Cancun

mar. 4/8

8:10 am-8:46 pm

2 stops12h 36m

$485

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

vie. 3/7

1:32 pm-11:04 am

2 stops20h 32m

Cancun

lun. 3/10

9:08 am-11:15 pm

2 stops14h 07m

$487

Des MoinesCozumel

DSM - CZM

DSMCZM

Des Moines

mar. 4/1

5:45 am-1:00 pm

1 stop8h 15m

Cozumel

mar. 4/8

2:20 pm-10:59 pm

1 stop7h 39m

$491

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

mar. 3/18

5:29 pm-10:28 am

1 stop17h 59m

Guadalajara Miguel Hidal

mar. 3/25

6:30 am-11:51 pm

2 stops16h 21m

$492

Des MoinesMonterrey

DSM - MTY

DSMMTY

Des Moines

mié. 3/26

5:45 am-11:36 am

1 stop6h 51m

Monterrey Gen Mariano Escobedo

mar. 6/3

12:25 pm-8:45 pm

1 stop7h 20m

$503

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

sáb. 3/29

5:45 am-5:34 pm

2 stops11h 49m

Cancun

sáb. 4/5

12:40 pm-10:59 pm

1 stop10h 19m

$513

Des MoinesCancún

DSM - CUN

DSMCUN

Des Moines

sáb. 3/8

5:00 am-8:48 pm

1 stop14h 48m

Cancun

jue. 3/13

2:51 pm-9:58 pm

1 stop7h 07m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 58 results
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Best time to book a flight from Des Moines to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Mexico

Get recent, data-driven insights about flights from Des Moines to Mexico including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Des Moines to Mexico?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MX?

Find hourly flight availability from Des Moines to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mexico as you normally would.

Rainfall in Mexico by month

Plan your trip to Mexico by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico when rainfall is around 0.0 in.

Temperature in Mexico by month

Plan your trip to Mexico by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated febrero 20, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta and Aeromexico from Des Moines to Mexico to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,220 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Aeromexico
7.5
Good
1,771 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,766 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Boarding

8.2

Comfort

8.1

Food

7.1

Overall

8.1

Entertainment

7.6

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mexico?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Mexico. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Mexico one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $155. Users have also found prices from $214 and $225 on American Airlines and Delta, respectively.

  • What are the most popular routes from Des Moines to Mexico?

    Most travelers choose Des Moines - Cancun, Des Moines - Cozumel or Des Moines - San José del Cabo Los Cabos when deciding on the best route from Des Moines to Mexico.

  • Can I find deals for flights from Des Moines to Mexico that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mexico.

  • Can I find deals for business class flights from Des Moines to Mexico?

    Yes. Cheapflights offers flight deals from Des Moines to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Mexico (average of $400). Flying from Des Moines to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Des Moines to Mexico

Discover the top 5 airlines that operate flights from Des Moines to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$350Average$494FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$384Average$576FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$388Average$684FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$441Average$608FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$460Average$621FlexibilityNo cancel feeOn-time63%
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