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$236+ Cheap flights from Panama City (PTY) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MEX
Mar 10 — Mar 171
Mon 3/10
Mon 3/17
1 adult, Economy
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The best prices from Panama City Tocumen Intl to Mexico City Benito Juarez are usually found in February or January, booked 84 days in advance, depart on a Thursday or Monday and return on a Thursday

Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 5, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$391
(Cheapflightsfares)

One-way from

$236
(Cheapflightsfares)

Popular in

June

Cheapest in

February

Average price

$441

Good round-trip deal

$417 or less

Good one-way deal

$450 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Mexico City Benito Juarez flights.
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From Panama City Tocumen Intl to Mexico City Benito Juarez
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One-way flight from Panama City Tocumen Intl to Mexico City Benito Juarez
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Highest demand for flights based on searches. 5% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Mexico City Benito Juarez.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Mexico City Benito Juarez.
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Find flight deals from Panama City to Mexico City

Cheapest flights from Panama City to Mexico City
Explore the most affordable flight options available from Panama City to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 5, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/318:10 pmPTY - MEX
1 stop15h 45mAvianca
Mon 4/72:00 pmMEX - PTY
1 stop9h 10mAvianca
Deal found 3/4$391
This Copa Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/229:34 pmPTY - MEX
Nonstop3h 41mCopa Airlines
Sun 6/295:50 amMEX - PTY
Nonstop3h 44mCopa Airlines
Deal found 3/4$402
This Mytrip deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1210:05 pmPTY - MEX
2 stops24h 40mMultiple Airlines
Sun 5/1812:55 pmMEX - PTY
2 stops10h 15mMultiple Airlines
Deal found 3/4$562

Find flights from Panama City to Mexico City within your budget

Customize your flight search to find flights from Panama City to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2025.

Fly from

Panama City

Fly to

Mexico City

Route

Depart

Return

Price

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Mon 3/31

8:10 pm-10:55 am

1 stop15h 45m

Mexico City Benito Juarez

Sun 4/6

12:40 am-4:30 pm

1 stop14h 50m

$391

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Fri 5/9

9:58 pm-1:00 am

Nonstop4h 02m

Mexico City Benito Juarez

Sun 5/11

1:40 am-6:18 am

Nonstop3h 38m

$417

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Mon 5/12

10:05 pm-9:45 pm

2 stops24h 40m

Mexico City Benito Juarez

Sun 5/18

12:55 pm-12:10 am

2 stops10h 15m

$562

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 4/2

3:50 pm-12:10 pm

2 stops21h 20m

Mexico City Benito Juarez

Mon 4/14

1:10 pm-12:15 pm

2 stops22h 05m

$917

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 5/1

3:20 am-6:05 pm

1 stop15h 45m

$236

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Thu 3/27

3:19 am-6:50 pm

2 stops16h 31m

$285

Panama CityMexico City

PTY - MEX

PTYMEX

Panama City Tocumen Intl

Wed 3/12

9:58 pm-1:00 am

Nonstop4h 02m

$473

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Compare providers for flights from Panama City to Mexico City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Mexico City in March.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Mexico City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Mexico City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Mexico City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Mexico City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Mexico City

Get recent, data-driven insights about flights from Panama City to Mexico City including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Mexico City. Price data was last updated on February 28, 2025.

The price you pay for your flight from Panama City to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 67 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Panama City to Mexico City (average of $400). Flying from Panama City to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MEX?

Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 5, 2025.

It’s typically best to fly out from Panama City to Mexico City in the afternoon. Doing so could potentially save you 20% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Panama City to Mexico City

Explore weekly flight availability from Panama City to Mexico City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 5, 2025.

The most flights from PTY to MEX are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Rainfall in Mexico City by month

Plan your trip to Mexico City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

Temperature in Mexico City by month

Plan your trip to Mexico City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated March 5, 2025.
Copa Airlines
7.6
Good
1,454 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,454 reviews
Copa Airlines
7.6
Good
1,454 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,454 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,341 reviews
Copa Airlines
7.6
Good
1,454 reviews

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Food

6.8

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Mexico City?

    Booking a flight from Panama City Tocumen Intl (PTY) to Mexico City Benito Juarez (MEX) is your only option if you wish to fly from Panama City to Mexico City. On a typical day, there are 6 flights from Tocumen Intl to Benito Juarez, all of which are around 3h 41m for a nonstop flight. You can also purchase a plane ticket from 2 airlines when you book a flight from Tocumen Intl to Mexico City.

  • How popular is this Panama City to Mexico City flight route?

    The Panama City Tocumen Intl to Mexico City Benito Juarez flight path was viewed by 6 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Mexico City round-trip?

    Cheapflights users have booked flights from Panama City to Mexico City round-trip from $391. Other airlines that can offer you cheap pricing are Copa Airlines, from $417, and American Airlines, from $917. Avianca is 17% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Panama City to Mexico City?

    Looking for the cheapest flight from Panama City to Mexico City? While on average our users pay $501, our data indicates the cheapest price to be $417. The most popular route (Panama City Tocumen Intl - Mexico City Benito Juarez), is priced around $387.

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Mexico City?

    Currently, May is the cheapest month in which you can book a flight from Panama City to Mexico City (average of $400). Flying from Panama City to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Valle de Bravo
Taxco

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Top 2 airlines flying from Panama City to Mexico City

Discover the top 2 airlines that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$339Average$417FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$390Average$510FlexibilityNo cancel feeOn-time70%
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