HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico City Federal District

$372+ Cheap flights from Knoxville (TYS) to Mexico City Federal District

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MEX
Jan 21 — Jan 281
Tue 1/21
Tue 1/28
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Mexico City Federal District with Cheapflights

1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”
2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.
3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Mexico City Federal District

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Mexico City Federal District (MXDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 16, 2025.

Round-trip from

$444
(Kiwi.com)

One-way from

$372
(Kiwi.com)
From Knoxville McGhee Tyson to Mexico City Federal District
Search Deals
One-way flight from Knoxville McGhee Tyson to Mexico City Federal District
Search Deals

Find flight deals from Knoxville to Mexico City Federal District

Cheapest flights from Knoxville to Mexico City Federal District
Explore the most affordable flight options available from Knoxville to Mexico City Federal District. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/191:30 pmTYS - MEX
1 stop8h 15mMultiple Airlines
Mon 3/2410:00 pmMEX - TYS
2 stops23h 31mMultiple Airlines
Deal found 1/16$444
This Aeromexico deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/185:45 amTYS - MEX
1 stop6h 30mAeromexico
Tue 3/257:05 amMEX - TYS
1 stop9h 33mAeromexico
Deal found 1/16$538
This Delta deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/175:45 amTYS - MEX
2 stops11h 15mDelta
Mon 3/39:01 amMEX - TYS
2 stops11h 38mDelta
Deal found 1/16$542
This American Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/56:20 amTYS - MEX
1 stop8h 35mAmerican Airlines
Tue 2/118:00 amMEX - TYS
1 stop11h 18mAmerican Airlines
Deal found 1/15$548
This United Airlines deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/177:00 amTYS - MEX
2 stops10h 40mUnited Airlines
Mon 4/212:15 pmMEX - TYS
1 stop7h 29mUnited Airlines
Deal found 1/16$551
This WestJet deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WestJet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1710:05 amTYS - MEX
2 stops31h 25mWestJet
Sat 3/221:15 amMEX - TYS
2 stops30h 05mWestJet
Deal found 1/16$1,112
This CheapOair deal was found by Cheapflights users on 1/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/171:59 pmTYS - MEX
2 stops23h 26mAir Canada
Mon 1/201:10 amMEX - TYS
2 stops14h 49mAir Canada
Deal found 1/16$1,181

Find flights from Knoxville to Mexico City Federal District within your budget

Customize your flight search to find flights from Knoxville to Mexico City Federal District that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 3/19

1:30 pm-7:45 pm

1 stop8h 15m

Mexico City Benito Juarez

Mon 3/24

10:00 pm-11:31 pm

2 stops23h 31m

$444

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Tue 3/18

5:45 am-10:15 am

1 stop6h 30m

Mexico City Benito Juarez

Tue 3/25

7:05 am-6:38 pm

1 stop9h 33m

$538

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 2/17

5:45 am-4:00 pm

2 stops11h 15m

Mexico City Benito Juarez

Mon 3/3

9:01 am-9:39 pm

2 stops11h 38m

$542

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Wed 2/5

6:20 am-1:55 pm

1 stop8h 35m

Mexico City Benito Juarez

Tue 2/11

8:00 am-8:18 pm

1 stop11h 18m

$548

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 4/17

7:00 am-3:40 pm

2 stops10h 40m

Mexico City Benito Juarez

Mon 4/21

2:15 pm-11:44 pm

1 stop7h 29m

$551

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Mon 3/17

10:05 am-3:30 pm

2 stops31h 25m

Mexico City Benito Juarez

Sat 3/22

1:15 am-9:20 am

2 stops30h 05m

$1,112

KnoxvilleMexico City

TYS - MEX

TYSMEX

Knoxville McGhee Tyson

Thu 2/13

5:45 am-12:45 am

2 stops20h 00m

Mexico City Benito Juarez

Mon 2/17

1:10 am-4:54 pm

2 stops14h 44m

$1,486

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/16

Best time to book a flight from Knoxville to Mexico City Federal District

Have a flexible travel schedule? Discover the best time to fly to Mexico City Federal District from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Knoxville to Mexico City Federal District

Get recent, data-driven insights about flights from Knoxville to Mexico City Federal District including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $400). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DF?

Find hourly flight availability from Knoxville to Mexico City Federal District. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 16, 2025.

When flying from Knoxville to Mexico City Federal District, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Mexico City Federal District by month

Plan your trip to Mexico City Federal District by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mexico City Federal District ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City Federal District when rainfall is around 0.0 in.

Temperature in Mexico City Federal District by month

Plan your trip to Mexico City Federal District by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mexico City Federal District, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mexico City Federal District

Get insights into the airlines that provide service to Mexico City Federal District. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City Federal District. Reviews last updated January 16, 2025.
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,511 reviews
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Aeromexico
7.5
Good
1,849 reviews
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,964 reviews
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

WestJet
7.2
Good
2,824 reviews
Delta
8.0
Very good
8,511 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

8.0

Crew

8.6

Boarding

8.2

Reviews

1 / 10

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mexico City Federal District. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mexico City Federal District?

    Knoxville McGhee Tyson (TYS) is the airport you will fly out of if you book a flight from Knoxville to Mexico City Federal District. It is only a 11.3 mi journey to McGhee Tyson (TYS) from Knoxville’s city center.

  • Can I find deals for flights from Knoxville to Mexico City Federal District that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mexico City Federal District flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mexico City Federal District?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mexico City Federal District.

  • Can I find deals for business class flights from Knoxville to Mexico City Federal District?

    Yes. Cheapflights offers flight deals from Knoxville to Mexico City Federal District by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mexico City Federal District?

    Currently, May is the cheapest month in which you can book a flight from Knoxville to Mexico City Federal District (average of $400). Flying from Knoxville to Mexico City Federal District in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Mexico City Federal District

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Cancún flights
Nashville to Cozumel flights
Knoxville to Cancún flights
Memphis to Cancún flights
Nashville to San José del Cabo flights
Knoxville to Cozumel flights
Memphis to Cozumel flights
Nashville to Mexico City flights
Memphis to San José del Cabo flights
Memphis to Tuxtla Gutiérrez flights
Chattanooga to Cancún flights
Nashville to Puerto Vallarta flights
Nashville to Santiago de Querétaro flights
Memphis to Mexico City flights
Chattanooga to Cozumel flights
Nashville to Guadalajara flights
Knoxville to Mexico City flights
Knoxville to Puerto Vallarta flights
Chattanooga to San José del Cabo flights
Knoxville to San José del Cabo flights
Blountville to Cancún flights
Memphis to Puerto Vallarta flights
Memphis to Guadalajara flights
Memphis to San Luis Potosí flights
Nashville to Mérida flights
Nashville to Monterrey flights
Knoxville to Guadalajara flights
Nashville to León flights
Nashville to Mazatlán flights
Memphis to León flights
Nashville to Villahermosa flights
Nashville to Veracruz flights
Chattanooga to Santiago de Querétaro flights
Nashville to Oaxaca flights
Nashville to Morelia flights
Blountville to Mexico City flights
Memphis to Morelia flights
Chattanooga to Puerto Vallarta flights
Memphis to Santiago de Querétaro flights
Nashville to Puebla City flights
Nashville to Hermosillo flights
Nashville to Chihuahua flights
Knoxville to Monterrey flights
Nashville to Acapulco flights
Knoxville to Saltillo flights
Memphis to Zacatecas flights
Memphis to Veracruz flights
Memphis to Tijuana flights
Nashville to Puerto Escondido flights

Top 4 airlines flying from Knoxville to Mexico City Federal District

Discover the top 4 airlines that operate flights from Knoxville to Mexico City Federal District. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$509Average$678FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$523Average$770FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$541Average$694FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$616Average$1,357FlexibilityNo cancel feeOn-timeN/A
100% Free
Cheapflights is completely free to use, so you can start saving the moment you arrive.
Book with Flexibility
Our users can plan ahead with confidence and find flights with no change fees
Travel Smart
Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.