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$85+ Cheap flights from Knoxville (TYS) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — PHX
Apr 22 — Apr 291
Tue 4/22
Tue 4/29
1 adult, Economy
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Cheapflights Tip: The best prices from Knoxville McGhee Tyson to Mesa are usually found in January or July, booked 59 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Knoxville to Mesa

Keep the following information in mind while searching for Knoxville to Mesa flight deals. Data was last updated April 17, 2025.

Round-trip from

$146
(Mytrip)

One-way from

$85
(Mytrip)

Popular in

February

Cheapest in

January

Average price

$316
From Knoxville McGhee Tyson to Mesa
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One-way flight from Knoxville McGhee Tyson to Mesa
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Knoxville to Mesa

Cheapest flights from Knoxville to Mesa
Explore the most affordable flight options available from Knoxville to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2025.

This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:55 pmTYS - PHX
Nonstop4h 21mAllegiant Air
Sun 5/114:06 pmPHX - TYS
Nonstop3h 22mAllegiant Air
Deal found 4/16$146
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/81:43 pmTYS - PHX
2 stops21h 30mMultiple Airlines
Sun 5/114:06 pmPHX - TYS
Nonstop3h 22mMultiple Airlines
Deal found 4/16$235
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:35 pmTYS - PHX
1 stop7h 38mUnited Airlines
Tue 6/311:39 pmPHX - TYS
1 stop7h 48mUnited Airlines
Deal found 4/16$251
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:20 amTYS - PHX
1 stop8h 02mAmerican Airlines
Sat 5/175:00 amPHX - TYS
1 stop6h 16mAmerican Airlines
Deal found 4/16$270
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/174:31 pmTYS - PHX
1 stop17h 53mFrontier
Sun 4/206:00 amPHX - TYS
1 stop6h 46mFrontier
Deal found 4/16$271
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/811:35 amTYS - PHX
1 stop9h 09mDelta
Mon 5/1211:35 pmPHX - TYS
1 stop7h 48mDelta
Deal found 4/17$289
This Alaska Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/23:09 pmTYS - PHX
2 stops20h 40mAlaska Airlines
Mon 5/59:00 amPHX - TYS
2 stops10h 07mAlaska Airlines
Deal found 4/16$439

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
Use the filters below to find and compare flights from Knoxville to Mesa that are best for you.

Fly from

Knoxville

Fly to

Mesa

Route

Depart

Return

Price

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 5/8

1:55 pm-3:16 pm

Nonstop4h 21m

Phoenix Sky Harbor Intl

Sun 5/11

4:06 pm-10:28 pm

Nonstop3h 22m

$146

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 5/8

1:43 pm-8:13 am

2 stops21h 30m

Phoenix Sky Harbor Intl

Sun 5/11

4:06 pm-10:28 pm

Nonstop3h 22m

$235

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Tue 5/20

5:35 pm-10:13 pm

1 stop7h 38m

Phoenix Sky Harbor Intl

Tue 6/3

11:39 pm-10:27 am

1 stop7h 48m

$251

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 5/15

5:20 am-10:22 am

1 stop8h 02m

Phoenix Sky Harbor Intl

Sat 5/17

5:00 am-2:16 pm

1 stop6h 16m

$270

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 5/29

5:30 pm-11:41 pm

1 stop9h 11m

Phoenix Sky Harbor Intl

Sun 6/1

7:18 am-4:29 pm

1 stop6h 11m

$277

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Thu 5/8

11:35 am-5:44 pm

1 stop9h 09m

Phoenix Sky Harbor Intl

Mon 5/12

11:35 pm-10:23 am

1 stop7h 48m

$289

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Fri 5/2

3:09 pm-8:49 am

2 stops20h 40m

Phoenix Sky Harbor Intl

Mon 5/5

9:00 am-10:07 pm

2 stops10h 07m

$439

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 6/8

6:00 am-6:50 am

Nonstop3h 50m

$85

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Tue 6/24

6:39 pm-10:19 pm

1 stop6h 40m

$126

KnoxvillePhoenix

TYS - PHX

TYSPHX

Knoxville McGhee Tyson

Sun 6/8

9:09 am-8:13 am

2 stops26h 04m

$156

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 13 results
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Best time to book a flight from Knoxville to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Mesa

How far ahead should I book a flight from Knoxville to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to Mesa. Price data was last updated on April 11, 2025.

Booking 59 days in advance of your planned departure date is, on average, the best time to get cheap flights from Knoxville to Mesa. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Knoxville to Mesa?

Currently, January is the cheapest month in which you can book a flight from Knoxville to Mesa (average of $258). Flying from Knoxville to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to MS9?

Find hourly flight availability from Knoxville to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Mesa as you normally would.

What is the cheapest day to fly from Knoxville to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Mesa. Price data was last updated on November 18, 2024.

Travelers seeking maximum savings on their Knoxville to Mesa flight should consider departing on Monday at noon when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated April 17, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Delta and United Airlines from Knoxville to Mesa to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Alaska Airlines
8.0
Very good
9,887 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Delta
8.0
Very good
7,916 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
United Airlines
7.4
Good
8,667 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
Allegiant Air
7.3
Good
734 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,887 reviews

Boarding

8.1

Comfort

7.9

Overall

8.0

Food

7.1

Crew

8.5

Entertainment

7.1

Reviews

1 / 20
4.0
Okay

Anonymous,Apr 2025

LAS - STS

flight was delayed both ways even tho the weather was clear >

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Mesa?

    For a flight from Knoxville to Mesa, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 outbound flights to Mesa per day. 5 airlines have flights to Mesa from Knoxville McGhee Tyson on a regular basis.

  • What are the cheapest airlines to fly from Knoxville to Mesa one-way?

    $85 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $126 and $181, respectively.

  • What are the cheapest flights from Knoxville to Mesa?

    Looking for the cheapest flight from Knoxville to Mesa? While on average our users pay $169, our data indicates the cheapest price to be $85. The most popular route (Knoxville McGhee Tyson - Phoenix Sky Harbor Intl), is priced around $110.

  • Can I find deals for flights from Knoxville to Mesa that include hotel bookings?

    Yes. In addition to deals on Knoxville to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Mesa.

  • Can I find deals for business class flights from Knoxville to Mesa?

    Yes. Cheapflights offers flight deals from Knoxville to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Knoxville to Mesa (average of $258). Flying from Knoxville to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Knoxville to Mesa

Discover the top 5 airlines that operate flights from Knoxville to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$118Average$233FlexibilityNo cancel feeOn-time88%
DeltaCheapest$128Average$466FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$138Average$278FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$284Average$598FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$509FlexibilityNo cancel feeOn-time71%

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