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$54+ Cheap flights from Des Moines (DSM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Jan 26 — Feb 21
Sun 1/26
Sun 2/2
1 adult, Economy
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The best prices from Des Moines to Mesa are usually found in November or October, booked 60 days in advance, depart on a Tuesday or Wednesday and return on a Wednesday

Cheap flight deals from Des Moines to Mesa

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Mesa (MS9). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 21, 2025.

Round-trip from

$218
(American Airlines)

One-way from

$54
(Frontier)

Popular in

March

Cheapest in

November

Average price

$327
From Des Moines to Mesa
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One-way flight from Des Moines to Mesa
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Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in January 2025
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Find flight deals from Des Moines to Mesa

Cheapest flights from Des Moines to Mesa
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 21, 2025.

This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/165:05 amDSM - PHX
Nonstop3h 04mAmerican Airlines
Wed 4/238:32 amPHX - DSM
Nonstop2h 47mAmerican Airlines
Deal found 1/21$218
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/23:12 pmDSM - PHX
1 stop9h 31mUnited Airlines
Tue 4/84:40 pmPHX - DSM
1 stop5h 02mUnited Airlines
Deal found 1/20$219
This Frontier deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:20 pmDSM - PHX
1 stop6h 35mFrontier
Fri 5/169:35 amPHX - DSM
1 stop6h 55mFrontier
Deal found 1/20$220
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/185:59 pmDSM - PHX
1 stop7h 38mDelta
Wed 3/261:44 pmPHX - DSM
1 stop7h 12mDelta
Deal found 1/20$237
This eDestinos deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/66:30 amDSM - PHX
2 stops33h 51mMultiple Airlines
Thu 3/137:28 pmPHX - DSM
2 stops25h 47mMultiple Airlines
Deal found 1/20$284
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/183:45 pmDSM - PHX
Nonstop3h 15mSouthwest
Tue 2/259:50 amPHX - DSM
Nonstop2h 50mSouthwest
Deal found 1/19$285

Find flights from Des Moines to Mesa within your budget

Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.

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Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 4/16

5:05 am-6:09 am

Nonstop3h 04m

Phoenix Sky Harbor Intl

Wed 4/23

8:32 am-1:19 pm

Nonstop2h 47m

$218

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 4/2

5:10 pm-9:34 pm

1 stop6h 24m

Phoenix Sky Harbor Intl

Mon 4/7

12:45 am-10:40 am

1 stop7h 55m

$219

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 5/9

7:20 pm-11:55 pm

1 stop6h 35m

Phoenix Sky Harbor Intl

Fri 5/16

9:35 am-6:30 pm

1 stop6h 55m

$220

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 3/18

5:59 pm-11:37 pm

1 stop7h 38m

Phoenix Sky Harbor Intl

Wed 3/26

1:44 pm-10:56 pm

1 stop7h 12m

$237

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 2/27

5:50 pm-12:25 am

1 stop7h 35m

Phoenix Sky Harbor Intl

Mon 3/3

7:05 am-4:05 pm

1 stop8h 00m

$282

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 3/6

6:30 am-3:21 pm

2 stops33h 51m

Phoenix Sky Harbor Intl

Thu 3/13

7:28 pm-11:15 pm

2 stops25h 47m

$284

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 4/23

7:27 pm-11:58 pm

1 stop6h 31m

$54

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 3/18

5:59 pm-9:55 pm

1 stop5h 56m

$119

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 3/11

3:30 pm-4:40 pm

Nonstop3h 10m

$140

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 2/26

2:37 pm-4:59 pm

Nonstop3h 22m

$143

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Des Moines to Mesa

Get recent, data-driven insights about flights from Des Moines to Mesa including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Des Moines to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Mesa. Price data was last updated on January 17, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Mesa, you should look to book at least 60 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Mesa?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MS9?

Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mesa as you normally would.

What is the cheapest day to fly from Des Moines to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Mesa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Mesa flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Des Moines to Mesa

Explore weekly flight availability from Des Moines to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 21, 2025.

The most flights from DSM to MS9 are scheduled on a Monday (6 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated January 21, 2025.
Read reviews from past customers who have flown American Airlines, United Airlines and Delta from Des Moines to Mesa. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Southwest
8.1
Very good
4,662 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Delta
8.0
Very good
8,521 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

United Airlines
7.4
Good
8,984 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Frontier
6.1
Okay
3,443 reviews
Southwest
8.1
Very good
4,662 reviews

Comfort

8.1

Crew

8.7

Food

7.2

Overall

8.1

Boarding

8.2

Entertainment

7.7

Reviews

1 / 10

We BARELY made the connection and when we got onboard we were treated like disobedient children who should have arrived earlier because we had to ask other passengers to move so we could sit with our kids. The flight attendants on the first flight were nice but the second one, they were snippy and fairly rude.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mesa?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Mesa from Des Moines. Booking flights from Des Moines (DSM) to Mesa should be relatively easy as there are 4 daily outbound flights to Mesa from 6 different airlines.

  • What are the cheapest airlines to fly from Des Moines to Mesa one-way?

    $54 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $119 and $140, respectively.

  • What are the most reliable airlines from Des Moines to Mesa?

    Before booking your flight to Mesa from Des Moines, check out the most reliable airlines to get you to your destination on time: Alaska Airlines (94%), Southwest (94%), Envoy Air( 93%).

  • What are the cheapest flights from Des Moines to Mesa?

    Looking at all options, your cheapest flight can be booked for $133. While the most popular route (Des Moines - Phoenix Sky Harbor Intl) can be booked for $184 on average our data indicates $951 when flying from Des Moines to Mesa.

  • Can I find deals for flights from Des Moines to Mesa that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mesa.

  • Can I find deals for business class flights from Des Moines to Mesa?

    Yes. Cheapflights offers flight deals from Des Moines to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Mesa

Discover the top 6 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$90Average$203FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$124Average$278FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$197Average$316FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$223Average$378FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$244Average$447FlexibilityNo cancel feeOn-time69%
DeltaCheapest$270Average$461FlexibilityNo cancel feeOn-timeN/A
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