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$88+ Cheap flights from Des Moines (DSM) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PHX
Mar 31 — Apr 71
Mon 3/31
Mon 4/7
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Mesa are usually found in January or November, booked 50 days in advance, depart on a Tuesday or Wednesday and return on a Saturday

Cheap flight deals from Des Moines to Mesa

Keep the following information in mind while searching for Des Moines to Mesa flight deals. Data was last updated March 26, 2025.

Round-trip from

$179
(Southwest)

One-way from

$90
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$460
From Des Moines to Mesa
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One-way flight from Des Moines to Mesa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in March 2025
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Find flight deals from Des Moines to Mesa

Cheapest flights from Des Moines to Mesa
Explore the most affordable flight options available from Des Moines to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2025.

This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/62:44 pmDSM - PHX
Nonstop3h 08mAmerican Airlines
Tue 5/138:35 amPHX - DSM
Nonstop2h 45mAmerican Airlines
Deal found 3/25$179
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/174:25 pmDSM - PHX
Nonstop3h 05mSouthwest
Tue 5/2011:20 amPHX - DSM
Nonstop2h 40mSouthwest
Deal found 3/25$209
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/148:17 pmDSM - PHX
1 stop5h 40mFrontier
Fri 4/186:00 amPHX - DSM
1 stop11h 17mFrontier
Deal found 3/25$238
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/75:30 pmDSM - PHX
1 stop8h 16mDelta
Mon 5/1211:25 pmPHX - DSM
1 stop9h 16mDelta
Deal found 3/24$247
This Mytrip deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/203:44 pmDSM - PHX
1 stop23h 44mMultiple Airlines
Fri 4/252:34 pmPHX - DSM
2 stops23h 07mMultiple Airlines
Deal found 3/25$291
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/85:45 amDSM - PHX
1 stop5h 01mUnited Airlines
Tue 5/137:00 amPHX - DSM
1 stop8h 50mUnited Airlines
Deal found 3/24$337

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
Use the filters below to find and compare flights from Des Moines to Mesa that are best for you.

Fly from

Des Moines

Fly to

Mesa

Route

Depart

Return

Price

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Tue 5/6

2:44 pm-3:52 pm

Nonstop3h 08m

Phoenix Sky Harbor Intl

Tue 5/13

8:35 am-1:20 pm

Nonstop2h 45m

$179

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 5/17

4:25 pm-5:30 pm

Nonstop3h 05m

Phoenix Sky Harbor Intl

Tue 5/20

11:20 am-4:00 pm

Nonstop2h 40m

$209

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 5/7

7:01 am-12:46 pm

1 stop7h 45m

Phoenix Sky Harbor Intl

Mon 5/12

11:35 pm-9:37 am

1 stop8h 02m

$247

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Fri 4/11

8:17 pm-7:04 am

1 stop12h 47m

Phoenix Sky Harbor Intl

Sun 4/13

9:00 pm-7:19 pm

1 stop20h 19m

$260

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sun 4/20

3:44 pm-1:28 pm

1 stop23h 44m

Phoenix Sky Harbor Intl

Fri 4/25

2:34 pm-3:41 pm

2 stops23h 07m

$291

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Thu 5/8

5:45 am-8:46 am

1 stop5h 01m

Phoenix Sky Harbor Intl

Wed 5/14

6:00 am-2:38 pm

1 stop6h 38m

$337

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sun 4/27

3:44 pm-1:28 pm

1 stop23h 44m

$88

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 4/30

2:37 pm-3:50 pm

Nonstop3h 13m

$90

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Sat 5/24

4:25 pm-5:30 pm

Nonstop3h 05m

$116

Des MoinesPhoenix

DSM - PHX

DSMPHX

Des Moines

Wed 4/30

7:27 pm-11:58 pm

1 stop6h 31m

$117

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/24

Showing 1-10 of 12 results
1
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Best time to book a flight from Des Moines to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Mesa

How far ahead should I book a flight from Des Moines to Mesa?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Mesa. Price data was last updated on March 21, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Mesa, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Mesa?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to MS9?

Find hourly flight availability from Des Moines to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Mesa as you normally would.

What is the cheapest day to fly from Des Moines to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Mesa. Price data was last updated on March 23, 2025.

Travelers seeking maximum savings on their Des Moines to Mesa flight should consider departing on Wednesday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 26, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Mesa. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Southwest
8.1
Very good
4,274 reviews
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Delta
8.0
Very good
7,891 reviews
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
United Airlines
7.4
Good
8,608 reviews
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.
Frontier
6.0
Okay
3,272 reviews
Southwest
8.1
Very good
4,274 reviews

Crew

8.6

Entertainment

7.6

Food

7.1

Boarding

8.2

Overall

8.1

Comfort

8.1

Reviews

1 / 20
8.0
Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Mesa?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Mesa from Des Moines. Booking flights from Des Moines (DSM) to Mesa should be relatively easy as there are 3 daily outbound flights to Mesa from 6 different airlines.

  • What are the cheapest airlines to fly from Des Moines to Mesa one-way?

    $90 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Southwest and Frontier, with prices starting from $116 and $117, respectively.

  • What are the most reliable airlines from Des Moines to Mesa?

    Before booking your flight to Mesa from Des Moines, check out the most reliable airlines to get you to your destination on time: Envoy Air (89%), Alaska Airlines (88%), American Airlines( 86%).

  • What are the cheapest flights from Des Moines to Mesa?

    Looking at all options, your cheapest flight can be booked for $132. While the most popular route (Des Moines - Phoenix Sky Harbor Intl) can be booked for $179 on average our data indicates $721 when flying from Des Moines to Mesa.

  • Can I find deals for flights from Des Moines to Mesa that include hotel bookings?

    Yes. In addition to deals on Des Moines to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Mesa.

  • Can I find deals for business class flights from Des Moines to Mesa?

    Yes. Cheapflights offers flight deals from Des Moines to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Mesa (average of $258). Flying from Des Moines to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Mesa

Discover the top 6 airlines that operate flights from Des Moines to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$93Average$225FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$123Average$242FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$200Average$329FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$217Average$366FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$433FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$461FlexibilityNo cancel feeOn-timeN/A
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