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$370+ Cheap flights from Columbia, MO (COU) to Mesa, AZ

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
COU — PHX
Apr 2 — Apr 91
Wed 4/2
Wed 4/9
1 adult, Economy
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Cheap flight deals from Columbia to Mesa

Keep the following information in mind while searching for Columbia to Mesa flight deals. Data was last updated March 28, 2025.

Round-trip from

$370
(American Airlines)

Popular in

June

Cheapest in

April

Average price

$579
From Columbia Regional to Mesa
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2025
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Find flight deals from Columbia to Mesa

Cheapest flights from Columbia to Mesa
Explore the most affordable flight options available from Columbia to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 28, 2025.

This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:29 pmCOU - PHX
1 stop8h 27mAmerican Airlines
Tue 4/2910:25 amPHX - COU
1 stop8h 12mAmerican Airlines
Deal found 3/26$370

Cheapflights Fare Finder

Customize your flight search to find flights from Columbia to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
Use the filters below to find and compare flights from Columbia to Mesa that are best for you.

Fly from

Columbia

Fly to

Mesa

Route

Depart

Return

Price

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 4/26

4:29 pm-10:56 pm

1 stop8h 27m

Phoenix Sky Harbor Intl

Tue 4/29

10:25 am-8:37 pm

1 stop8h 12m

$370

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Best time to book a flight from Columbia to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mesa

What is the cheapest month to book a flight from Columbia, Missouri to Mesa?

Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Mesa (average of $258). Flying from Columbia, Missouri to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from COU to MS9?

Find hourly flight availability from Columbia to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 28, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbia, Missouri to Mesa as you normally would.

Rainfall in Mesa by month

Plan your trip to Mesa by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

Temperature in Mesa by month

Plan your trip to Mesa by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 28, 2025.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Overall

7.2

Food

6.5

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
6.0
Good

sheila,Mar 2025

DFW - MSP

We were delayed for 3 hours with no real reason or offer for compensation

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mesa?

    For a flight from Columbia to Mesa, you will be flying from Columbia Regional. Columbia Regional (COU) is just 11.1 mi from the center of the city. Columbia Regional is the only Columbia airport and it handles 0 outbound flights to Mesa per day. 1 airline has flights to Mesa from Columbia Regional on a regular basis.

  • Can I find deals for flights from Columbia to Mesa that include hotel bookings?

    Yes. In addition to deals on Columbia to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mesa.

  • Can I find deals for business class flights from Columbia to Mesa?

    Yes. Cheapflights offers flight deals from Columbia to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia, Missouri to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Columbia, Missouri to Mesa (average of $258). Flying from Columbia, Missouri to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Columbia to Mesa

Discover the top airline that operate flights from Columbia to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$370Average$530FlexibilityNo cancel feeOn-time71%
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