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Medellín

$139+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
Apr 8 — Apr 151
Tue 4/8
Tue 4/15
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated April 3, 2025.

Round-trip from

$345
(Mytrip)

One-way from

$139
(Mytrip)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
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Find flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 3, 2025.

This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/310:57 amCLT - MDE
1 stop27h 03mSpirit Airlines
Wed 5/71:53 pmMDE - CLT
1 stop29h 47mSpirit Airlines
Deal found 4/2$345
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/36:58 amCLT - MDE
1 stop7h 17mMultiple Airlines
Wed 5/146:10 amMDE - CLT
2 stops14h 50mMultiple Airlines
Deal found 4/2$393
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/277:00 amCLT - MDE
1 stop15h 10mUnited Airlines
Wed 6/49:45 amMDE - CLT
1 stop11h 31mUnited Airlines
Deal found 4/2$425
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/610:21 pmCLT - MDE
1 stop15h 21mAmerican Airlines
Sat 9/135:50 amMDE - CLT
1 stop12h 40mAmerican Airlines
Deal found 4/1$445
This Mytrip deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/23:55 pmGSP - MDE
1 stop22h 20mMultiple Airlines
Sun 5/111:53 pmMDE - GSP
2 stops24h 12mMultiple Airlines
Deal found 4/2$458
This Delta deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/17:59 pmCLT - MDE
2 stops43h 36mDelta
Sun 6/810:54 pmMDE - CLT
2 stops24h 01mDelta
Deal found 4/1$526
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:20 amMYR - MDE
2 stops13h 40mAmerican Airlines
Wed 10/82:40 pmMDE - MYR
2 stops20h 37mAmerican Airlines
Deal found 4/2$531
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2710:52 amCHS - MDE
1 stop13h 43mAmerican Airlines
Sat 9/65:50 amMDE - CHS
1 stop16h 02mAmerican Airlines
Deal found 4/2$533
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/186:18 pmGSP - MDE
1 stop19h 32mAmerican Airlines
Sat 6/216:00 amMDE - GSP
1 stop15h 11mAmerican Airlines
Deal found 4/2$565
This United deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:30 amCHS - MDE
2 stops15h 40mUnited Airlines
Sat 5/249:45 amMDE - CHS
2 stops23h 51mUnited Airlines
Deal found 4/2$566
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/56:55 pmSAV - MDE
2 stops27h 15mUnited Airlines
Tue 5/139:45 amMDE - SAV
1 stop10h 43mUnited Airlines
Deal found 4/2$567
This Copa Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2110:24 amCLT - MDE
2 stops22h 54mCopa Airlines
Wed 8/612:45 pmMDE - CLT
2 stops20h 03mCopa Airlines
Deal found 4/2$567

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
Use the filters below to find and compare flights from South Carolina to Medellín that are best for you.

Fly from

South Carolina

Fly to

Medellín

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 5/3

10:57 am-1:00 pm

1 stop27h 03m

Medellín Jose Maria Cordova Intl

Wed 5/7

1:53 pm-8:40 pm

1 stop29h 47m

$345

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 5/3

6:58 am-1:15 pm

1 stop7h 17m

Medellín Jose Maria Cordova Intl

Wed 5/14

6:10 am-10:00 pm

2 stops14h 50m

$393

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Tue 5/27

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Wed 6/4

9:45 am-10:16 pm

1 stop11h 31m

$425

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sat 9/6

10:21 pm-12:42 pm

1 stop15h 21m

Medellín Jose Maria Cordova Intl

Sat 9/13

5:50 am-7:30 pm

1 stop12h 40m

$445

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 5/2

3:55 pm-1:15 pm

1 stop22h 20m

Medellín Jose Maria Cordova Intl

Sun 5/11

1:53 pm-3:05 pm

2 stops24h 12m

$458

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Sun 6/1

7:59 pm-2:35 pm

2 stops43h 36m

Medellín Jose Maria Cordova Intl

Sun 6/8

10:54 pm-11:55 pm

2 stops24h 01m

$526

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Wed 8/27

10:52 am-11:35 pm

1 stop13h 43m

Medellín Jose Maria Cordova Intl

Sat 9/6

5:50 am-10:52 pm

1 stop16h 02m

$533

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 5/18

6:18 pm-12:50 pm

1 stop19h 32m

Medellín Jose Maria Cordova Intl

Fri 6/20

12:40 am-11:57 pm

1 stop22h 17m

$565

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

Sat 5/17

6:30 am-9:10 pm

2 stops15h 40m

Medellín Jose Maria Cordova Intl

Sat 5/24

9:45 am-10:36 am

2 stops23h 51m

$566

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

Wed 5/21

10:24 am-8:18 am

2 stops22h 54m

Medellín Jose Maria Cordova Intl

Wed 8/6

12:45 pm-9:48 am

2 stops20h 03m

$567

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/2

Showing 1-10 of 23 results
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Medellín

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $378). Flying from South Carolina to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDE?

Find hourly flight availability from South Carolina to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 3, 2025.

When flying from South Carolina to Medellín, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 3, 2025.
To help decide which airline to fly from South Carolina to Medellín, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,897 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,400 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,754 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,619 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,897 reviews

Food

7.3

Comfort

8.0

Crew

8.5

Boarding

8.2

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Medellín one-way?

    $139 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Copa Airlines and Avianca, with prices starting from $302 and $529, respectively.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Greenville - Medellín Jose Maria Cordova Intl or Charleston - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $378). Flying from South Carolina to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Medellín

Discover the top 3 airlines that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$199Average$416FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$465Average$681FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$565Average$801FlexibilityNo cancel feeOn-time81%

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