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$130+ Cheap flights from South Carolina to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MDE
feb. 25 — mar. 41
mar. 2/25
mar. 3/4
1 adult, Economy
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Cheap flight deals from South Carolina to Medellín

Keep the following information in mind while searching for South Carolina to Medellín flight deals. Data was last updated febrero 20, 2025.

Round-trip from

$331
(Cheapflightsfares)

One-way from

$130
(Mytrip)
From South Carolina to Medellín
Search Deals
One-way flight from South Carolina to Medellín
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Find flight deals from South Carolina to Medellín

Cheapest flights from South Carolina to Medellín
Explore the most affordable flight options available from South Carolina to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on febrero 20, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/176:55 amCLT - MDE
1 stop7h 13mSpirit Airlines
mié. 4/162:14 pmMDE - CLT
1 stop7h 24mSpirit Airlines
Deal found 2/19$331
This Avianca Connect deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 3/157:24 pmCLT - MDE
1 stop22h 21mMultiple Airlines
mar. 3/188:20 amMDE - CLT
1 stop28h 02mMultiple Airlines
Deal found 2/19$361
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/710:28 amCHS - MDE
2 stops33h 31mMultiple Airlines
lun. 4/145:15 amMDE - CHS
2 stops27h 53mMultiple Airlines
Deal found 2/20$402
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 3/2812:35 pmSAV - MDE
1 stop25h 48mMultiple Airlines
vie. 4/42:18 pmMDE - SAV
1 stop7h 55mMultiple Airlines
Deal found 2/19$409
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/186:30 amCLT - MDE
2 stops23h 12mUnited Airlines
vie. 7/49:45 amMDE - CLT
2 stops23h 37mUnited Airlines
Deal found 2/19$419
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/710:28 amCHS - MDE
2 stops27h 29mSpirit Airlines
lun. 4/142:14 pmMDE - CHS
1 stop18h 54mSpirit Airlines
Deal found 2/20$425
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 5/166:00 amGSP - MDE
1 stop15h 15mAmerican Airlines
sáb. 5/246:00 amMDE - GSP
1 stop10h 48mAmerican Airlines
Deal found 2/19$506
This LATAM Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 4/267:10 amCLT - MDE
2 stops15h 40mLATAM Airlines
vie. 5/212:01 amMDE - CLT
2 stops17h 21mLATAM Airlines
Deal found 2/18$512
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 6/217:45 pmSAV - MDE
1 stop17h 55mAmerican Airlines
vie. 6/272:15 amMDE - SAV
1 stop15h 50mAmerican Airlines
Deal found 2/19$535
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 3/256:55 amSAV - MDE
1 stop15h 10mUnited Airlines
mié. 4/29:45 amMDE - SAV
1 stop11h 13mUnited Airlines
Deal found 2/19$551
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/1711:09 amCLT - MDE
2 stops10h 07mAmerican Airlines
mié. 3/1912:20 amMDE - CLT
1 stop15h 58mAmerican Airlines
Deal found 2/19$556
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/2412:33 pmSAV - MDE
2 stops10h 57mDelta
mié. 4/26:31 amMDE - SAV
2 stops13h 47mDelta
Deal found 2/19$562

Find flights from South Carolina to Medellín within your budget

Customize your flight search to find flights from South Carolina to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.

Fly from

South Carolina

Fly to

Medellín

Route

Depart

Return

Price

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

lun. 3/17

6:55 am-1:08 pm

1 stop7h 13m

Medellín Jose Maria Cordova Intl

mié. 4/16

2:14 pm-10:38 pm

1 stop7h 24m

$331

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sáb. 3/15

7:24 pm-4:45 pm

1 stop22h 21m

Medellín Jose Maria Cordova Intl

mar. 3/18

8:20 am-1:22 pm

1 stop28h 02m

$361

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

lun. 4/7

10:28 am-6:59 pm

2 stops33h 31m

Medellín Jose Maria Cordova Intl

lun. 4/14

5:15 am-10:08 am

2 stops27h 53m

$402

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

vie. 3/28

12:35 pm-1:23 pm

1 stop25h 48m

Medellín Jose Maria Cordova Intl

vie. 4/4

2:18 pm-11:13 pm

1 stop7h 55m

$409

CharlestonMedellín

CHS - MDE

CHSMDE

Charleston

lun. 4/7

10:28 am-12:57 pm

2 stops27h 29m

Medellín Jose Maria Cordova Intl

lun. 4/14

2:14 pm-10:08 am

1 stop18h 54m

$425

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sáb. 5/3

10:21 am-9:10 pm

2 stops11h 49m

Medellín Jose Maria Cordova Intl

mar. 5/6

9:45 am-10:21 am

2 stops23h 36m

$426

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

vie. 5/16

6:00 am-8:15 pm

1 stop15h 15m

Medellín Jose Maria Cordova Intl

sáb. 5/24

6:00 am-5:48 pm

1 stop10h 48m

$506

CharlotteMedellín

CLT - MDE

CLTMDE

Charlotte Douglas

sáb. 4/26

7:10 am-9:50 pm

2 stops15h 40m

Medellín Jose Maria Cordova Intl

vie. 5/2

12:01 am-6:22 pm

2 stops17h 21m

$512

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

sáb. 6/21

7:45 pm-12:40 pm

1 stop17h 55m

Medellín Jose Maria Cordova Intl

vie. 6/27

2:15 am-7:05 pm

1 stop15h 50m

$535

SavannahMedellín

SAV - MDE

SAVMDE

Savannah/Hilton Head

mar. 3/25

6:55 am-9:05 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

mié. 4/2

9:45 am-9:58 pm

1 stop11h 13m

$551

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 34 results
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Best time to book a flight from South Carolina to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Medellín

Get recent, data-driven insights about flights from South Carolina to Medellín including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Medellín?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $378). Flying from South Carolina to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MDE?

Find hourly flight availability from South Carolina to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated febrero 20, 2025.

When flying from South Carolina to Medellín, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated febrero 20, 2025.
To help decide which airline to fly from South Carolina to Medellín, see what other customers have to say about Delta, Copa Airlines and LATAM Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta
8.0
Very good
8,219 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines
7.6
Good
1,510 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines
7.5
Good
1,795 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines
7.4
Good
8,765 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,219 reviews

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20

10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Medellín one-way?

    $138 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Avianca and United Airlines, with prices starting from $270 and $300, respectively.

  • What are the most popular routes from South Carolina to Medellín?

    While some choose either Greenville - Medellín Jose Maria Cordova Intl or Savannah/Hilton Head - Medellín Jose Maria Cordova Intl, Charlotte Douglas - Medellín Jose Maria Cordova Intl is the most popular route from South Carolina to Medellín.

  • Can I find deals for flights from South Carolina to Medellín that include hotel bookings?

    Yes. In addition to deals on South Carolina to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Medellín.

  • Can I find deals for business class flights from South Carolina to Medellín?

    Yes. Cheapflights offers flight deals from South Carolina to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Medellín?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Medellín (average of $378). Flying from South Carolina to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Medellín

Discover the top 3 airlines that operate flights from South Carolina to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated febrero 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$199Average$416FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$383Average$684FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$728Average$770FlexibilityNo cancel feeOn-time81%
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