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$142+ Cheap flights from Panama City (PTY) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MDE
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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The best prices from Panama City Tocumen Intl to Medellín are usually found in April or July, booked 78 days in advance, depart on a Monday or Saturday and return on a Friday

Cheap flight deals from Panama City to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 20, 2025.

Round-trip from

$265
(Copa Airlines)

One-way from

$142
(Copa Airlines)

Popular in

November

Cheapest in

April

Average price

$172
From Panama City Tocumen Intl to Medellín
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One-way flight from Panama City Tocumen Intl to Medellín
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Highest demand for flights based on searches. 10% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($2 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from Panama City to Medellín

Cheapest flights from Panama City to Medellín
Explore the most affordable flight options available from Panama City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Copa Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/209:27 pmPTY - MDE
Nonstop1h 24mCopa Airlines
Mon 3/245:05 amMDE - PTY
Nonstop1h 29mCopa Airlines
Deal found 2/19$265
This Priceline deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/253:34 pmPTY - MDE
Nonstop1h 10mAvianca
Wed 2/261:25 pmMDE - PTY
Nonstop1h 15mAvianca
Deal found 2/18$297
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/287:01 amPTY - MDE
Nonstop1h 22mMultiple Airlines
Sun 3/26:00 pmMDE - PTY
Nonstop1h 15mMultiple Airlines
Deal found 2/19$355
This Aeromexico deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/63:02 pmPTY - MDE
1 stop9h 32mAeromexico
Wed 10/82:02 amMDE - PTY
1 stop11h 45mAeromexico
Deal found 2/18$550

Find flights from Panama City to Medellín within your budget

Customize your flight search to find flights from Panama City to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

Panama City

Fly to

Medellín

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 5/7

12:46 pm-2:11 pm

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Tue 5/13

5:06 am-6:34 am

Nonstop1h 28m

$307

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 6/9

3:25 am-8:00 am

1 stop4h 35m

Medellín Jose Maria Cordova Intl

Mon 6/16

7:56 pm-12:10 am

1 stop4h 14m

$308

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Tue 4/1

3:40 pm-4:55 pm

Nonstop1h 15m

Medellín Jose Maria Cordova Intl

Fri 4/4

12:01 am-8:55 am

1 stop8h 54m

$524

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Fri 8/1

3:02 pm-12:34 am

1 stop9h 32m

Medellín Jose Maria Cordova Intl

Mon 8/4

2:02 am-1:47 pm

1 stop11h 45m

$571

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 5/5

3:20 pm-9:10 pm

1 stop29h 50m

Medellín Jose Maria Cordova Intl

Wed 5/14

9:45 am-2:14 pm

1 stop28h 29m

$1,583

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sat 3/15

9:09 am-10:33 am

Nonstop1h 24m

$142

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Fri 3/14

3:19 am-7:41 am

1 stop4h 22m

$161

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/18

Best time to book a flight from Panama City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City to Medellín

Get recent, data-driven insights about flights from Panama City to Medellín including ideal travel times, pricing trends, and more.

How far ahead should I book a flight from Panama City to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Medellín. Price data was last updated on February 14, 2025.

Booking 78 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Medellín?

Currently, January is the cheapest month in which you can book a flight from Panama City to Medellín (average of $378). Flying from Panama City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MDE?

Find hourly flight availability from Panama City to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

It’s typically best to fly out from Panama City to Medellín at noon. Doing so could potentially save you 42% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Panama City to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Panama City to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama City to Medellín flight should consider departing on Friday at noon when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Panama City to Medellín

Explore weekly flight availability from Panama City to Medellín. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 20, 2025.

The most flights from PTY to CO1 are scheduled on a Wednesday (16 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (10 on average).

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Copa Airlines, Aeromexico and United Airlines from Panama City to Medellín by reading reviews from past customers. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,516 reviews

Boarding

7.9

Comfort

7.4

Food

6.9

Entertainment

6.9

Overall

7.6

Crew

8.1

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Copa Airlines
7.6
Good
1,516 reviews
Copa Airlines
7.6
Good
1,516 reviews

Boarding

7.9

Comfort

7.4

Food

6.9

Entertainment

6.9

Overall

7.6

Crew

8.1

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Aeromexico
7.5
Good
1,773 reviews
Copa Airlines
7.6
Good
1,516 reviews

Boarding

7.9

Comfort

7.4

Food

6.9

Entertainment

6.9

Overall

7.6

Crew

8.1

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

United Airlines
7.4
Good
8,768 reviews
Copa Airlines
7.6
Good
1,516 reviews

Boarding

7.9

Comfort

7.4

Food

6.9

Entertainment

6.9

Overall

7.6

Crew

8.1

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Avianca
6.8
Okay
2,437 reviews
Copa Airlines
7.6
Good
1,516 reviews

Boarding

7.9

Comfort

7.4

Food

6.9

Entertainment

6.9

Overall

7.6

Crew

8.1

Reviews

1 / 20

4.0
Okay

Anonymous,Jan 2025

PTY - ORD

Our first flight was good. The return flight is a different story. I picked and paid for seat 11D and then checked in with that same seat assignment. When I boarded the plain I somehow had lost that seat and was stuck in a middle seat that I was not happy with for a 5 hour flight. The food was terrible - I could not even eat the chicken and "cheese" sandwich it was so bad. The difference in the two flights was amazing - the one from the Chicago to Panama City was great - seating and food. The return flight was very different.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Medellín?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Medellín. 3 airlines have flights from Tocumen Intl to Medellín on a regular basis. Booking flights from Panama City Tocumen Intl to Medellín should not be difficult; the airport handles an average of 12 outbound flights to Medellín per day.

  • What are the cheapest airlines flying from Panama City to Medellín round-trip?

    According to our current data, Copa Airlines ($265), Avianca ($302), and Aeromexico ($571) offers the cheapest pricing from Panama City to Medellín.

  • What are the most reliable airlines from Panama City to Medellín?

    The top 3 most reliable airlines when flying from Panama City to Medellín are Turkish Airlines (93%), United Airlines (91%) and Copa Airlines (88%).

  • What are the cheapest flights from Panama City to Medellín?

    On average you can expect to pay $209 for a flight from Panama City to Medellín. The cheapest flight overall is $119 while the most popular route, (Panama City Tocumen Intl - Medellín Jose Maria Cordova Intl) is currently priced at $151.

  • Can I find deals for flights from Panama City to Medellín that include hotel bookings?

    Yes. In addition to deals on Panama City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Medellín.

  • Can I find deals for business class flights from Panama City to Medellín?

    Yes. Cheapflights offers flight deals from Panama City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Medellín (average of $378). Flying from Panama City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Panama City to Medellín

Discover the top 3 airlines that operate flights from Panama City to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$117Average$155FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$139Average$261FlexibilityNo cancel feeOn-time70%
AviancaCheapest$168Average$221FlexibilityNo cancel feeOn-time71%
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