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$134+ Cheap flights from Panama City (PTY) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MDE
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Medellín are usually found in July or February, booked 57 days in advance, depart on a Monday or Saturday and return on a Friday

Cheap flight deals from Panama City to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 15, 2025.

Round-trip from

$232
(Copa Airlines)

One-way from

$134
(Copa Airlines)

Popular in

November

Cheapest in

July

Average price

$170
From Panama City Tocumen Intl to Medellín
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One-way flight from Panama City Tocumen Intl to Medellín
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Highest demand for flights based on searches. 10% potential increase in price ($22 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Panama City to Medellín

Cheapest flights from Panama City to Medellín
Explore the most affordable flight options available from Panama City to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This Copa Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/199:04 amPTY - MDE
Nonstop1h 25mCopa Airlines
Thu 5/229:15 amMDE - PTY
Nonstop1h 28mCopa Airlines
Deal found 4/14$232
This Avianca deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/185:25 pmPTY - MDE
1 stop4h 07mAvianca
Sun 4/205:58 amMDE - PTY
1 stop4h 12mAvianca
Deal found 4/15$261
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/273:20 amPTY - MDE
1 stop5h 10mMultiple Airlines
Thu 5/13:01 pmMDE - PTY
2 stops9h 09mMultiple Airlines
Deal found 4/14$412

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Panama City to Medellín that are best for you.

Fly from

Panama City

Fly to

Medellín

Route

Depart

Return

Price

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 5/19

9:04 am-10:29 am

Nonstop1h 25m

Medellín Jose Maria Cordova Intl

Thu 5/22

9:15 am-10:43 am

Nonstop1h 28m

$232

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Mon 8/4

11:20 am-12:30 pm

Nonstop1h 10m

Medellín Jose Maria Cordova Intl

Sun 8/10

1:25 pm-2:40 pm

Nonstop1h 15m

$263

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Sun 4/27

3:20 am-8:30 am

1 stop5h 10m

Medellín Jose Maria Cordova Intl

Thu 5/1

3:01 pm-12:10 am

2 stops9h 09m

$412

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Thu 5/29

10:00 am-9:10 pm

1 stop11h 10m

Medellín Jose Maria Cordova Intl

Wed 6/4

12:15 am-4:12 pm

1 stop15h 57m

$1,583

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Thu 4/24

7:20 am-8:45 am

Nonstop1h 25m

$134

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Wed 4/23

11:20 am-12:30 pm

Nonstop1h 10m

$139

Panama CityMedellín

PTY - MDE

PTYMDE

Panama City Tocumen Intl

Fri 4/25

10:05 pm-8:02 pm

1 stop21h 57m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Best time to book a flight from Panama City to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Medellín

How far ahead should I book a flight from Panama City to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Medellín. Price data was last updated on April 11, 2025.

Booking 57 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Medellín. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Medellín?

Currently, January is the cheapest month in which you can book a flight from Panama City to Medellín (average of $378). Flying from Panama City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MDE?

Find hourly flight availability from Panama City to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

It’s typically best to fly out from Panama City to Medellín at noon. Doing so could potentially save you 43% on the flight price compared to flying in the afternoon, which is usually more expensive.

What is the cheapest day to fly from Panama City to Medellín?

Use this chart to determine the cheapest time to fly round-trip from Panama City to Medellín. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama City to Medellín flight should consider departing on Friday at noon when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Panama City to Medellín

Explore weekly flight availability from Panama City to Medellín. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 15, 2025.

The most flights from PTY to CO1 are scheduled on a Monday (19 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (13 on average).

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 15, 2025.
Copa Airlines
7.6
Good
1,408 reviews

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,408 reviews
Copa Airlines
7.6
Good
1,408 reviews

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
United Airlines
7.4
Good
8,658 reviews
Copa Airlines
7.6
Good
1,408 reviews

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Avianca
6.7
Okay
2,313 reviews
Copa Airlines
7.6
Good
1,408 reviews

Food

6.8

Crew

8.1

Boarding

7.8

Entertainment

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Medellín?

    Panama City Tocumen Intl (PTY), located 11.4 mi from the city center, is the airport you fly out of when you book flights from Panama City to Medellín. 3 airlines have flights from Tocumen Intl to Medellín on a regular basis. Booking flights from Panama City Tocumen Intl to Medellín should not be difficult; the airport handles an average of 15 outbound flights to Medellín per day.

  • What are the cheapest airlines flying from Panama City to Medellín round-trip?

    According to our current data, Copa Airlines ($232), Avianca ($263), and United Airlines ($1,583) offers the cheapest pricing from Panama City to Medellín.

  • What are the most reliable airlines from Panama City to Medellín?

    The top 3 most reliable airlines when flying from Panama City to Medellín are Turkish Airlines (100%), KLM (98%) and Copa Airlines (96%).

  • What are the cheapest flights from Panama City to Medellín?

    On average you can expect to pay $215 for a flight from Panama City to Medellín. The cheapest flight overall is $138 while the most popular route, (Panama City Tocumen Intl - Medellín Jose Maria Cordova Intl) is currently priced at $139.

  • Can I find deals for flights from Panama City to Medellín that include hotel bookings?

    Yes. In addition to deals on Panama City to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Medellín.

  • Can I find deals for business class flights from Panama City to Medellín?

    Yes. Cheapflights offers flight deals from Panama City to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Medellín (average of $378). Flying from Panama City to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Panama City to Medellín

Discover the top 3 airlines that operate flights from Panama City to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$126Average$156FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$142Average$267FlexibilityNo cancel feeOn-time70%
AviancaCheapest$168Average$221FlexibilityNo cancel feeOn-time71%

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