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$274+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
Apr 30 — May 71
Wed 4/30
Wed 5/7
1 adult, Economy
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Cheapflights Tip: The best prices from Greenville to Medellín are usually found in March or January, booked 51 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2025.

Round-trip from

$400
(Kiwi.com)

One-way from

$274
(Copa Airlines)

Popular in

December

Cheapest in

March

Average price

$641
From Greenville to Medellín
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One-way flight from Greenville to Medellín
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Highest demand for flights based on searches. 3% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/192:50 pmGSP - MDE
1 stop23h 08mMultiple Airlines
Sun 5/251:53 pmMDE - GSP
1 stop17h 55mMultiple Airlines
Deal found 4/25$400
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:31 amGSP - MDE
2 stops15h 24mAmerican Airlines
Tue 10/285:50 amMDE - GSP
2 stops14h 32mAmerican Airlines
Deal found 4/25$510
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/115:34 pmGSP - MDE
1 stop12h 08mUnited Airlines
Thu 7/1712:15 amMDE - GSP
1 stop15h 35mUnited Airlines
Deal found 4/24$546
This LATAM Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/217:35 amGSP - MDE
2 stops12h 54mLATAM Airlines
Sat 6/214:22 amMDE - GSP
2 stops27h 38mLATAM Airlines
Deal found 4/25$677
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/277:05 amGSP - MDE
2 stops17h 20mDelta
Mon 5/54:12 amMDE - GSP
2 stops18h 41mDelta
Deal found 4/25$882

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Greenville

Fly to

Medellín

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 5/19

2:50 pm-12:58 pm

1 stop23h 08m

Medellín Jose Maria Cordova Intl

Sun 5/25

1:53 pm-8:48 am

1 stop17h 55m

$400

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

5:31 am-7:55 pm

2 stops15h 24m

Medellín Jose Maria Cordova Intl

Tue 10/28

5:50 am-9:22 pm

2 stops14h 32m

$510

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 7/11

5:34 pm-4:42 am

1 stop12h 08m

Medellín Jose Maria Cordova Intl

Thu 7/17

12:15 am-4:50 pm

1 stop15h 35m

$546

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 5/21

7:35 am-7:29 pm

2 stops12h 54m

Medellín Jose Maria Cordova Intl

Sat 6/21

4:22 am-9:00 am

2 stops27h 38m

$677

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 10/1

10:10 am-9:37 am

2 stops24h 27m

$274

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 7/24

5:34 pm-4:42 am

1 stop12h 08m

$310

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 5/31

7:35 am-5:25 pm

2 stops10h 50m

$621

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

How far ahead should I book a flight from Greenville to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Medellín. Price data was last updated on April 18, 2025.

The best time to book flights from Greenville to Medellín is 50 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, January is the cheapest month in which you can book a flight from Greenville to Medellín (average of $378). Flying from Greenville to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to MDE?

Find hourly flight availability from Greenville to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 25, 2025.

One of the essential ways to save on airfare from Greenville to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 24% on airfare.

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 25, 2025.
Copa Airlines
7.6
Good
1,411 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
Copa Airlines
7.6
Good
1,411 reviews
Copa Airlines
7.6
Good
1,411 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
LATAM Airlines
7.5
Good
1,767 reviews
Copa Airlines
7.6
Good
1,411 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
United Airlines
7.4
Good
8,685 reviews
Copa Airlines
7.6
Good
1,411 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.
American Airlines
7.2
Good
10,000 reviews
Copa Airlines
7.6
Good
1,411 reviews

Entertainment

6.8

Boarding

7.8

Crew

8.1

Food

6.8

Comfort

7.4

Overall

7.6

Reviews

1 / 20
4.0
Okay

Anonymous,Mar 2025

PTY - JFK

There was no chance for me to choose a seat even if I were willing to pay extra for it when I was doing the check-in on line. My seats were the last row on the plane and they didn't have enough food to give me. I had to eat what was left after everybody else had their choice of food. This is unacceptable. Everyone should have a choice. I paid money just like everybody else. Never had this happened on any other airlines even if my seats were last row on the plane.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 2 different airlines.

  • What are the cheapest airlines flying from Greenville to Medellín round-trip?

    American Airlines, at $510, was found to be the cheapest airline from Greenville to Medellín.Alternate airlines to your destination round-trip include United Airlines and LATAM Airlines. Users have found that American Airlines is 25% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Greenville to Medellín one-way?

    $274 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on United Airlines and LATAM Airlines, with prices starting from $310 and $621, respectively.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Medellín (average of $378). Flying from Greenville to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Greenville to Medellín

Discover the top 2 airlines that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$467Average$718FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$565Average$801FlexibilityNo cancel feeOn-time81%

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