HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Madrid

$507+ Cheap flights from Panama to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
abr. 6 — abr. 131
dom. 4/6
dom. 4/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to Madrid with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to Madrid

Keep the following information in mind while searching for Panama to Madrid flight deals. Data was last updated abril 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$692
(KLM)

One-way from

$507
(SmartFares)

Popular in

July

Cheapest in

March

Average price

$723

Good round-trip deal

$733 or less

Good one-way deal

$526 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Madrid Barajas flights.
Search Deals
From Panama to Madrid Barajas
Search Deals
One-way flight from Panama to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($70 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals
Price to beat on a round-trip flight from Panama to Madrid Barajas.
Search Deals
Price to beat on a one-way flight from Panama to Madrid Barajas.
Search Deals

Find flight deals from Panama to Madrid

Cheapest flights from Panama to Madrid
Explore the most affordable flight options available from Panama to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 1, 2025.

This KLM deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/207:55 pmPTY - MAD
1 stop13h 50mMultiple Airlines
vie. 5/301:05 pmMAD - PTY
1 stop34h 45mMultiple Airlines
Deal found 3/31$692
This KLM deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 6/116:50 pmPTY - MAD
1 stop31h 45mKLM
mar. 9/28:25 pmMAD - PTY
1 stop27h 25mKLM
Deal found 3/31$702
This Gotogate deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 5/105:35 pmPTY - MAD
Nonstop9h 50mIberia
dom. 6/112:00 pmMAD - PTY
Nonstop11h 05mIberia
Deal found 3/31$718
This Air Europa deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/238:25 pmPTY - MAD
Nonstop9h 50mAir Europa
mar. 10/143:05 pmMAD - PTY
Nonstop10h 35mAir Europa
Deal found 3/31$723
This Air France deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/187:55 pmPTY - MAD
1 stop13h 50mAir France
mar. 9/306:00 amMAD - PTY
1 stop18h 45mAir France
Deal found 4/1$747
This Avianca deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/83:20 amPTY - MAD
1 stop13h 10mAvianca
mié. 5/211:10 pmMAD - PTY
1 stop18h 00mAvianca
Deal found 4/1$793
This Turkish Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 4/298:00 pmPTY - MAD
1 stop19h 30mTurkish Airlines
sáb. 5/1012:00 pmMAD - PTY
2 stops37h 20mTurkish Airlines
Deal found 3/31$804
This United Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/19:45 amPTY - MAD
2 stops39h 05mUnited Airlines
mié. 10/2211:15 amMAD - PTY
2 stops34h 04mUnited Airlines
Deal found 3/31$844

Cheapflights Fare Finder

Customize your flight search to find flights from Panama to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 1, 2025.
Use the filters below to find and compare flights from Panama to Madrid that are best for you.

Fly from

Panama

Fly to

Madrid

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mar. 5/20

7:55 pm-4:45 pm

1 stop13h 50m

Madrid Barajas

vie. 5/30

1:05 pm-4:50 pm

1 stop34h 45m

$692

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mié. 6/11

6:50 pm-9:35 am

1 stop31h 45m

Madrid Barajas

mar. 9/2

8:25 pm-4:50 pm

1 stop27h 25m

$702

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mar. 6/3

7:55 pm-11:10 pm

1 stop20h 15m

Madrid Barajas

sáb. 6/21

10:05 am-7:03 pm

1 stop15h 58m

$717

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

sáb. 5/10

5:35 pm-10:25 am

Nonstop9h 50m

Madrid Barajas

dom. 6/1

12:00 pm-4:05 pm

Nonstop11h 05m

$718

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

dom. 5/11

8:25 pm-1:15 pm

Nonstop9h 50m

Madrid Barajas

dom. 5/18

3:05 pm-6:40 pm

Nonstop10h 35m

$723

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

jue. 5/8

3:20 am-11:30 pm

1 stop13h 10m

Madrid Barajas

mié. 5/21

1:10 pm-12:10 am

1 stop18h 00m

$793

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mar. 4/29

8:00 pm-10:30 pm

1 stop19h 30m

Madrid Barajas

sáb. 5/10

12:00 pm-6:20 pm

2 stops37h 20m

$804

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

mié. 5/21

10:55 pm-6:40 am

2 stops24h 45m

Madrid Barajas

mié. 6/4

11:15 am-4:12 pm

2 stops35h 57m

$844

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

jue. 5/8

3:20 am-11:30 pm

1 stop13h 10m

$507

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

lun. 5/12

8:25 pm-1:15 pm

Nonstop9h 50m

$515

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/31

Showing 1-10 of 13 results
1
2

Best time to book a flight from Panama to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Madrid

What is the cheapest month to book a flight from Panama to Madrid?

Currently, November is the cheapest month in which you can book a flight from Panama to Madrid (average of $543). Flying from Panama to Madrid in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to MAD?

Find hourly flight availability from Panama to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 1, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to Madrid at noon. If you’re flexible enough to do this you can expect to save up to 4% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Panama to Madrid?

Use this chart to determine the cheapest time to fly round-trip from Panama to Madrid. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama to Madrid flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Wednesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Madrid by month

Plan your trip to Madrid by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Madrid ranges from 0.4 - 2.4 inches per month. November is typically the wettest month, when rainfall can reach 2.4 in. July is typically the driest time to visit Madrid when rainfall is around 0.4 in.

Temperature in Madrid by month

Plan your trip to Madrid by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated abril 1, 2025.
To help decide which airline to fly from Panama to Madrid, see what other customers have to say about KLM, Air France and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
KLM
7.8
Good
1,323 reviews
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Air France
7.4
Good
1,425 reviews
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
United Airlines
7.4
Good
8,615 reviews
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Turkish Airlines
7.3
Good
3,748 reviews
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.
Iberia
7.0
Good
2,655 reviews
KLM
7.8
Good
1,323 reviews

Overall

7.8

Food

7.3

Boarding

7.8

Comfort

7.7

Crew

8.4

Entertainment

7.2

Reviews

1 / 20
8.0
Excellent

Anonymous,Mar 2025

LBA - AMS

Overall, the flight from Leeds Bradford to Amsterdam was at expected. The crew were efficient at boarding and professional on board. The only issue was extremely slow check in at Leeds Bradford which was very frustrating.

Related info for your journey

Find useful and relevant information for your journey from Panama to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Madrid from Panama?

    Madrid Barajas (MAD), located 8.5 mi from the city center, is the airport you fly into when you book flights from Panama to Madrid.

  • How popular is this Panama to Madrid flight route?

    This flight path from Panama to Madrid Barajas was viewed by 17 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Panama to Madrid one-way?

    $507 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Air Europa and Turkish Airlines, with prices starting from $515 and $553, respectively.

  • What are the most reliable airlines from Panama to Madrid?

    Consider Air Europa (90%), Etihad Airways (90%) or China Eastern (90%) when booking your flight. These represent the most reliable airlines when flying from Panama to Madrid.

  • What are the cheapest flights from Panama to Madrid?

    On average you can expect to pay $2,012 for a flight from Panama to Madrid. The cheapest flight overall is $459 while the most popular route, (Panama City Tocumen Intl - Madrid Barajas) is currently priced at $693.

  • Can I find deals for flights from Panama to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Madrid.

  • Can I find deals for business class flights from Panama to Madrid?

    Yes. Cheapflights offers flight deals from Panama to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Panama to Madrid (average of $543). Flying from Panama to Madrid in June is currently the most expensive (average of $1,101). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama?

Book flights to Panama if you plan to visit one of these locations
Segovia
Fuenlabrada

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 7 airlines flying from Panama to Madrid

Discover the top 7 airlines that operate flights from Panama to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$543Average$677FlexibilityNo cancel feeOn-time71%
Air EuropaCheapest$644Average$777FlexibilityNo cancel feeOn-time83%
IberiaCheapest$651Average$821FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$666Average$776FlexibilityNo cancel feeOn-time77%
KLMCheapest$670Average$796FlexibilityNo cancel feeOn-time75%
United AirlinesCheapest$678Average$774FlexibilityNo cancel feeOn-time69%
Turkish AirlinesCheapest$735Average$800FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.