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$48+ Cheap flights from South Carolina to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
Feb 25 — Mar 41
Tue 2/25
Tue 3/4
1 adult, Economy
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Cheap flight deals from South Carolina to Louisville

Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated February 20, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$148
(Mytrip)

One-way from

$48
(Booking.com)

Popular in

March

Cheapest in

July

Average price

$296
Provider with most accurate pricing for Myrtle Beach Intl-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Louisville Intl flights.
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From South Carolina to Louisville Intl
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One-way flight from South Carolina to Louisville Intl
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Highest demand for flights based on searches. 12% potential increase in price ($47 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in February 2025
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Find flight deals from South Carolina to Louisville

Cheapest flights from South Carolina to Louisville
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2025.

This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1510:48 amCHS - SDF
1 stop7h 33mSpirit Airlines
Mon 3/177:16 pmSDF - CHS
2 stops18h 48mSpirit Airlines
Deal found 2/20$148
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2410:07 amCLT - SDF
1 stop3h 42mDelta
Mon 5/267:30 pmSDF - CLT
1 stop4h 26mDelta
Deal found 2/20$157
This FlightHub deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/195:35 pmCLT - SDF
1 stop5h 23mSpirit Airlines
Thu 3/206:00 amSDF - CLT
1 stop10h 30mSpirit Airlines
Deal found 2/19$165
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/710:37 pmMYR - SDF
1 stop19h 44mSpirit Airlines
Tue 3/117:16 pmSDF - MYR
1 stop22h 20mSpirit Airlines
Deal found 2/20$177
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2411:14 amCHS - SDF
1 stop11h 03mMultiple Airlines
Sun 4/276:12 pmSDF - CHS
1 stop14h 15mMultiple Airlines
Deal found 2/20$198
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/87:59 pmCHS - SDF
1 stop3h 57mDelta
Sat 5/102:59 pmSDF - CHS
1 stop3h 55mDelta
Deal found 2/19$232
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/75:46 pmSAV - SDF
1 stop6h 40mAmerican Airlines
Wed 3/195:00 amSDF - SAV
1 stop5h 22mAmerican Airlines
Deal found 2/20$232
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/87:35 pmCHS - SDF
1 stop4h 45mSouthwest
Wed 3/1212:55 pmSDF - CHS
2 stops7h 55mSouthwest
Deal found 2/20$237
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/77:15 amSAV - SDF
1 stop6h 16mUnited Airlines
Wed 3/192:15 pmSDF - SAV
2 stops9h 50mUnited Airlines
Deal found 2/20$238
This Lucky2Go deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lucky2Go is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/137:05 amCHS - SDF
2 stops31h 40mBreeze Airways
Mon 3/1711:03 amSDF - CHS
1 stop11h 56mBreeze Airways
Deal found 2/19$239
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/77:20 pmGSP - SDF
1 stop4h 38mDelta
Tue 3/1111:05 amSDF - GSP
1 stop5h 29mDelta
Deal found 2/20$262
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/273:02 pmGSP - SDF
1 stop17h 31mAllegiant Air
Mon 3/310:43 amSDF - GSP
1 stop9h 55mAllegiant Air
Deal found 2/20$268

Find flights from South Carolina to Louisville within your budget

Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.

Fly from

South Carolina

Fly to

Louisville

Route

Depart

Return

Price

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Sat 3/15

10:48 am-6:21 pm

1 stop7h 33m

Louisville Intl

Mon 3/17

7:16 pm-2:04 pm

2 stops18h 48m

$148

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Sat 5/24

10:07 am-1:49 pm

1 stop3h 42m

Louisville Intl

Mon 5/26

7:30 pm-11:56 pm

1 stop4h 26m

$157

CharlotteLouisville

CLT - SDF

CLTSDF

Charlotte Douglas

Wed 3/19

5:35 pm-10:58 pm

1 stop5h 23m

Louisville Intl

Thu 3/20

6:00 am-4:30 pm

1 stop10h 30m

$165

Myrtle BeachLouisville

MYR - SDF

MYRSDF

Myrtle Beach Intl

Fri 3/7

10:37 pm-6:21 pm

1 stop19h 44m

Louisville Intl

Tue 3/11

7:16 pm-5:36 pm

1 stop22h 20m

$177

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 4/24

11:14 am-10:17 pm

1 stop11h 03m

Louisville Intl

Sun 4/27

6:12 pm-8:27 am

1 stop14h 15m

$198

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Fri 3/7

5:46 pm-12:26 am

1 stop6h 40m

Louisville Intl

Wed 3/19

5:00 am-10:22 am

1 stop5h 22m

$232

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 5/8

7:59 pm-11:56 pm

1 stop3h 57m

Louisville Intl

Sat 5/10

2:59 pm-6:54 pm

1 stop3h 55m

$232

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Sat 3/8

7:35 pm-12:20 am

1 stop4h 45m

Louisville Intl

Wed 3/12

12:55 pm-8:50 pm

2 stops7h 55m

$237

SavannahLouisville

SAV - SDF

SAVSDF

Savannah/Hilton Head

Fri 3/7

7:15 am-1:31 pm

1 stop6h 16m

Louisville Intl

Wed 3/19

2:15 pm-12:05 am

2 stops9h 50m

$238

CharlestonLouisville

CHS - SDF

CHSSDF

Charleston

Thu 3/13

7:05 am-2:45 pm

2 stops31h 40m

Louisville Intl

Mon 3/17

11:03 am-10:59 pm

1 stop11h 56m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/20

Showing 1-10 of 50 results
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Best time to book a flight from South Carolina to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Louisville

Get recent, data-driven insights about flights from South Carolina to Louisville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Louisville?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $299). Flying from South Carolina to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to SDF?

Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 20, 2025.

When flying from South Carolina to Louisville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Louisville by month

Plan your trip to Louisville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.

Temperature in Louisville by month

Plan your trip to Louisville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated February 20, 2025.
Get a feel of what it's like to fly with Southwest, Breeze Airways and Delta from South Carolina to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Southwest
8.1
Very good
4,411 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Breeze Airways
8.1
Very good
150 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Delta
8.0
Very good
8,219 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

United Airlines
7.4
Good
8,765 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Allegiant Air
7.3
Good
765 reviews
Southwest
8.1
Very good
4,411 reviews

Crew

8.7

Overall

8.1

Boarding

8.2

Entertainment

7.6

Food

7.1

Comfort

8.1

Reviews

1 / 20

2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from South Carolina?

    Louisville Intl (SDF) is the airport you will fly into if you book a flight from South Carolina to Louisville. It is only a 5.3 mi journey from Louisville Intl (SDF) to Louisville’s city center.

  • How popular is this South Carolina to Louisville flight route?

    Within the past month, 3 users have taken a look at flights from South Carolina to Louisville Intl.

  • What are the cheapest airlines to fly from South Carolina to Louisville one-way?

    For one-way options, check prices for Allegiant Air. According to our data, you can fly for as low as $48. Users have also found prices from $76 and $84 on Spirit Airlines and Delta, respectively.

  • What are the most popular routes from South Carolina to Louisville?

    Most travelers choose Charlotte Douglas - Louisville Intl, Charleston - Louisville Intl or Columbia Metropolitan - Louisville Intl when deciding on the best route from South Carolina to Louisville.

  • Can I find deals for flights from South Carolina to Louisville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Louisville.

  • Can I find deals for business class flights from South Carolina to Louisville?

    Yes. Cheapflights offers flight deals from South Carolina to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Louisville?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $299). Flying from South Carolina to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Jeffersonville
Corydon
Elizabethtown
Bardstown

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Top 4 airlines flying from South Carolina to Louisville

Discover the top 4 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$70Average$143FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$165Average$343FlexibilityNo cancel feeOn-time71%
DeltaCheapest$175Average$339FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$233Average$338FlexibilityNo cancel feeOn-time69%
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