$45+ Cheap flights from South Carolina to Louisville (SDF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SDF
Apr 6 — Apr 131
1 adult, Economy
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Find cheap flights from South Carolina to Louisville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Louisville
Keep the following information in mind while searching for South Carolina to Louisville flight deals. Data was last updated April 1, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $139 (Priceline) |
One-way from | $45 (FlightHub) |
Popular in | March |
Cheapest in | July |
Average price | $356 |
Find flight deals from South Carolina to Louisville
Cheapest flights from South Carolina to LouisvilleExplore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.
Explore the most affordable flight options available from South Carolina to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2025.
This Priceline deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/97:05 amCHS - SDF
Nonstop1h 47mBreeze Airways
Mon 5/128:35 pmSDF - CHS
Nonstop1h 36mBreeze Airways
Deal found 3/31![Breeze Airways logo]()
$139
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1512:08 pmMYR - SDF
1 stop10h 09mSpirit Airlines
Sat 4/198:41 amSDF - MYR
Nonstop1h 38mSpirit Airlines
Deal found 3/31![Spirit Airlines logo]()
$148
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2810:57 amCLT - SDF
1 stop6h 20mSpirit Airlines
Wed 4/305:05 amSDF - CLT
1 stop11h 33mSpirit Airlines
Deal found 3/30![Spirit Airlines logo]()
$173
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2810:57 amCLT - SDF
1 stop6h 20mMultiple Airlines
Mon 5/56:19 pmSDF - CLT
1 stop22h 19mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/106:34 amCHS - SDF
1 stop5h 07mAmerican Airlines
Tue 5/136:00 amSDF - CHS
1 stop4h 18mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$199
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/298:15 amSAV - SDF
2 stops24h 32mMultiple Airlines
Mon 6/25:23 pmSDF - SAV
Nonstop1h 33mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$201
This Mytrip deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2410:25 amCHS - SDF
1 stop11h 52mSpirit Airlines
Sun 4/276:12 pmSDF - CHS
2 stops15h 24mSpirit Airlines
Deal found 4/1![Spirit Airlines logo]()
$203
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/168:00 amSAV - SDF
2 stops24h 28mAllegiant Air
Mon 8/188:23 pmSDF - SAV
Nonstop1h 33mAllegiant Air
Deal found 3/31![Allegiant Air logo]()
$217
This Mytrip deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/19:59 pmMYR - SDF
1 stop19h 35mMultiple Airlines
Wed 5/72:07 pmSDF - MYR
2 stops30h 58mMultiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$220
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/247:48 pmMYR - SDF
1 stop4h 25mAmerican Airlines
Tue 4/298:58 amSDF - MYR
1 stop5h 13mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$228
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/306:20 pmGSP - SDF
1 stop5h 53mAmerican Airlines
Wed 5/78:15 pmSDF - GSP
1 stop3h 35mAmerican Airlines
Deal found 3/31![American Airlines logo]()
$229
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/264:14 pmCAE - SDF
1 stop6h 01mAmerican Airlines
Wed 4/307:21 pmSDF - CAE
1 stop4h 46mAmerican Airlines
Deal found 4/1![American Airlines logo]()
$229
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
Use the filters below to find and compare flights from South Carolina to Louisville that are best for you.
Fly from
South Carolina
Fly to
Louisville
Route
Depart
Return
Price
CharlestonLouisville
CHS - SDF
CHSSDF
Charleston
Fri 5/9
7:05 am-8:52 am
Nonstop1h 47m
Louisville Intl
Mon 5/12
8:35 pm-10:11 pm
Nonstop1h 36m
$139
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Tue 4/15
12:08 pm-10:17 pm
1 stop10h 09m
Louisville Intl
Sat 4/19
8:41 am-10:19 am
Nonstop1h 38m
$148
CharlotteLouisville
CLT - SDF
CLTSDF
Charlotte Douglas
Mon 4/28
10:57 am-5:17 pm
1 stop6h 20m
Louisville Intl
Wed 4/30
5:05 am-4:38 pm
1 stop11h 33m
$173
CharlotteLouisville
CLT - SDF
CLTSDF
Charlotte Douglas
Mon 4/28
10:57 am-5:17 pm
1 stop6h 20m
Louisville Intl
Mon 5/5
6:19 pm-4:38 pm
1 stop22h 19m
$189
CharlestonLouisville
CHS - SDF
CHSSDF
Charleston
Sat 5/10
6:34 am-11:41 am
1 stop5h 07m
Louisville Intl
Tue 5/13
6:00 am-10:18 am
1 stop4h 18m
$199
SavannahLouisville
SAV - SDF
SAVSDF
Savannah/Hilton Head
Thu 5/29
8:15 am-8:47 am
2 stops24h 32m
Louisville Intl
Mon 6/2
5:23 pm-6:56 pm
Nonstop1h 33m
$201
CharlestonLouisville
CHS - SDF
CHSSDF
Charleston
Fri 4/25
10:32 am-10:17 pm
1 stop11h 45m
Louisville Intl
Sun 4/27
6:12 pm-9:36 am
2 stops15h 24m
$204
SavannahLouisville
SAV - SDF
SAVSDF
Savannah/Hilton Head
Sat 8/16
8:00 am-8:28 am
2 stops24h 28m
Louisville Intl
Mon 8/18
8:23 pm-9:56 pm
Nonstop1h 33m
$217
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Thu 5/1
9:59 pm-5:34 pm
1 stop19h 35m
Louisville Intl
Wed 5/7
2:07 pm-9:05 pm
2 stops30h 58m
$220
Myrtle BeachLouisville
MYR - SDF
MYRSDF
Myrtle Beach Intl
Thu 4/24
7:48 pm-12:13 am
1 stop4h 25m
Louisville Intl
Tue 4/29
8:58 am-2:11 pm
1 stop5h 13m
$228
Showing 1-10 of 52 results
Best time to book a flight from South Carolina to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Louisville
What is the cheapest month to book a flight from South Carolina to Louisville?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Louisville (average of $299). Flying from South Carolina to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SDF?
Find hourly flight availability from South Carolina to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2025.
When flying from South Carolina to Louisville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Rainfall in Louisville by month
Plan your trip to Louisville by taking into account the average rainfall totals by month.
In terms of precipitation, rainfall in Louisville ranges from 3.1 - 5.3 inches per month. May is typically the wettest month, when rainfall can reach 5.3 in. September is typically the driest time to visit Louisville when rainfall is around 3.1 in.
Temperature in Louisville by month
Plan your trip to Louisville by taking into account the average temperature totals by month.
If weather is an important factor for your trip to Louisville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 35.6 F).
Reviews of airlines servicing Louisville
Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated April 1, 2025.
Get a feel of what it's like to fly with Breeze Airways, Southwest and Delta from South Carolina to Louisville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Crew
8.8
Food
6.7
Boarding
8.3
Entertainment
6.6
Overall
8.1
Comfort
8.2
Reviews
1 / 11
10.0
ExcellentDena,Dec 2024
LAS - BDL
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near South Carolina?
Book flights to South Carolina if you plan to visit one of these locationsJeffersonville
Corydon
Elizabethtown
Bardstown
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for South Carolina to Louisville
See prices for flight routes from nearby airports that may be better suited for you.
Top 4 airlines flying from South Carolina to Louisville
Discover the top 4 airlines that operate flights from South Carolina to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$60 | Average$144 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$165 | Average$339 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$175 | Average$335 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$233 | Average$338 | FlexibilityNo cancel fee | On-time69% |