HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisiana

$102+ Cheap flights from Knoxville (TYS) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Apr 20 — Apr 271
Sun 4/20
Sun 4/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Louisiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Knoxville to Louisiana

Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated April 15, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$199
(American Airlines)

One-way from

$102
(Mytrip)

Popular in

October

Cheapest in

September

Average price

$413
Provider with most accurate pricing for Knoxville McGhee Tyson-New Orleans Louis Armstrong flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-New Orleans Louis Armstrong flights.
Search Deals
From Knoxville McGhee Tyson to Louisiana
Search Deals
One-way flight from Knoxville McGhee Tyson to Louisiana
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($23 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Knoxville to Louisiana

Cheapest flights from Knoxville to Louisiana
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 15, 2025.

This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:28 pmTYS - MSY
1 stop6h 47mAmerican Airlines
Wed 5/285:23 amMSY - TYS
1 stop4h 05mAmerican Airlines
Deal found 4/15$199
This Mytrip deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/309:03 pmTYS - MSY
1 stop12h 22mMultiple Airlines
Fri 6/68:05 pmMSY - TYS
1 stop11h 29mMultiple Airlines
Deal found 4/15$223
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:45 amTYS - BTR
1 stop4h 49mDelta
Sun 6/16:59 pmBTR - TYS
1 stop3h 52mDelta
Deal found 4/15$243
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/227:25 pmTYS - MSY
1 stop4h 57mDelta
Sun 8/249:57 amMSY - TYS
1 stop4h 11mDelta
Deal found 4/14$249
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/109:05 amTYS - BTR
1 stop4h 20mAmerican Airlines
Sun 5/115:30 amBTR - TYS
1 stop5h 11mAmerican Airlines
Deal found 4/15$254
This United deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2110:56 amTYS - MSY
2 stops11h 46mUnited Airlines
Sun 8/245:25 pmMSY - TYS
1 stop4h 54mUnited Airlines
Deal found 4/14$377
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/25:24 amTYS - AEX
1 stop5h 37mAmerican Airlines
Mon 5/56:28 pmAEX - TYS
1 stop4h 30mAmerican Airlines
Deal found 4/14$456
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/107:00 amTYS - BTR
2 stops13h 45mUnited Airlines
Sun 5/115:05 amBTR - TYS
2 stops16h 40mUnited Airlines
Deal found 4/15$548
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/275:24 amTYS - LFT
1 stop5h 45mAmerican Airlines
Thu 5/16:22 pmLFT - TYS
1 stop4h 33mAmerican Airlines
Deal found 4/14$683

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.

Fly from

Knoxville

Fly to

Louisiana

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 5/24

6:28 pm-12:15 am

1 stop6h 47m

New Orleans Louis Armstrong

Wed 5/28

5:23 am-10:28 am

1 stop4h 05m

$199

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 5/30

9:03 pm-8:25 am

1 stop12h 22m

New Orleans Louis Armstrong

Fri 6/6

8:05 pm-8:34 am

1 stop11h 29m

$223

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Thu 5/29

5:45 am-9:34 am

1 stop4h 49m

Baton Rouge Ryan

Sun 6/1

6:59 pm-11:51 pm

1 stop3h 52m

$243

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 8/22

7:25 pm-11:22 pm

1 stop4h 57m

New Orleans Louis Armstrong

Sun 8/24

9:57 am-3:08 pm

1 stop4h 11m

$249

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 5/10

9:05 am-12:25 pm

1 stop4h 20m

Baton Rouge Ryan

Sun 5/11

5:30 am-11:41 am

1 stop5h 11m

$254

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 8/21

10:56 am-9:42 pm

2 stops11h 46m

New Orleans Louis Armstrong

Sun 8/24

5:25 pm-11:19 pm

1 stop4h 54m

$377

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Fri 5/2

5:24 am-10:01 am

1 stop5h 37m

Alexandria

Mon 5/5

6:28 pm-11:58 pm

1 stop4h 30m

$456

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Sat 5/10

7:00 am-7:45 pm

2 stops13h 45m

Baton Rouge Ryan

Sun 5/11

5:05 am-10:45 pm

2 stops16h 40m

$548

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sun 4/27

5:24 am-10:09 am

1 stop5h 45m

Lafayette Regional

Thu 5/1

6:22 pm-11:55 pm

1 stop4h 33m

$683

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 5/23

12:45 pm-12:30 am

1 stop12h 45m

$102

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/15

Showing 1-10 of 15 results
1
2

Best time to book a flight from Knoxville to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Louisiana

What is the cheapest month to book a flight from Knoxville to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to LA?

Find hourly flight availability from Knoxville to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 15, 2025.

When flying from Knoxville to Louisiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Louisiana by month

Plan your trip to Louisiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Louisiana ranges from 3.3 - 6.4 inches per month. June is typically the wettest month, when rainfall can reach 6.4 in. October is typically the driest time to visit Louisiana when rainfall is around 3.3 in.

Temperature in Louisiana by month

Plan your trip to Louisiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Louisiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated April 15, 2025.
Read through reviews of airlines operating flights from Knoxville to Louisiana, such as Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,918 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,918 reviews
Delta
8.0
Very good
7,918 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,658 reviews
Delta
8.0
Very good
7,918 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,918 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.9

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Louisiana?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Louisiana from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to Louisiana one-way?

    $126 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $201 and $408, respectively.

  • What are the most popular routes from Knoxville to Louisiana?

    The most popular flight routes from Knoxville to Louisiana are Knoxville McGhee Tyson - New Orleans Louis Armstrong, Knoxville McGhee Tyson - Baton Rouge Ryan and Knoxville McGhee Tyson - Lafayette Regional.

  • Can I find deals for flights from Knoxville to Louisiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Louisiana.

  • Can I find deals for business class flights from Knoxville to Louisiana?

    Yes. Cheapflights offers flight deals from Knoxville to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Knoxville to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Seattle flights
Nashville to LaGuardia flights
Nashville to John F Kennedy Intl flights
Nashville to Las Vegas flights
Nashville to Los Angeles flights
Nashville to Denver flights
Nashville to Newark flights
Memphis to Los Angeles flights
Nashville to Dallas/Fort Worth flights
Nashville to Fort Lauderdale flights
Memphis to Las Vegas flights
Nashville to Orlando flights
Memphis to O'Hare Intl flights
Nashville to Miami flights
Chattanooga to LaGuardia flights
Nashville to Sky Harbor Intl flights
Memphis to Miami flights
Memphis to Newark flights
Memphis to LaGuardia flights
Nashville to Boston flights
Nashville to San Francisco flights
Memphis to Seattle flights
Knoxville to LaGuardia flights
Memphis to Hobby flights
Memphis to Dallas/Fort Worth flights
Nashville to Honolulu flights
Memphis to John F Kennedy Intl flights
Nashville to Dulles Intl flights
Nashville to Hobby flights
Memphis to Orlando flights
Memphis to Denver flights
Chattanooga to John F Kennedy Intl flights
Knoxville to O'Hare Intl flights
Nashville to Reagan-National flights
Knoxville to Denver flights
Nashville to Tampa flights
Nashville to O'Hare Intl flights
Memphis to Baltimore flights
Nashville to Portland flights
Memphis to George Bush Intcntl flights
Memphis to Reagan-National flights
Knoxville to John F Kennedy Intl flights
Nashville to George Bush Intcntl flights
Chattanooga to O'Hare Intl flights
Memphis to Boston flights
Nashville to Salt Lake City flights
Knoxville to Dulles Intl flights
Memphis to Dulles Intl flights
Nashville to Baltimore flights
Nashville to Raleigh flights

Top 3 airlines flying from Knoxville to Louisiana

Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$171Average$330FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$226Average$349FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$247Average$378FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.