HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

Cheap flights from South Padre Island, TX to Knoxville (TYS)

MFE — TYS
Apr 6 — Apr 131
Sun 4/6
Sun 4/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Padre Island to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Best time to book a flight from South Padre Island to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Padre Island with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Padre Island to Knoxville

What is the cheapest month to book a flight from South Padre Island to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Padre Island to Knoxville (average of $296). Flying from South Padre Island to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Related info for your journey

Find useful and relevant information for your journey from South Padre Island to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South Padre Island?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from South Padre Island to Knoxville. 1 airline have flights to McGhee Tyson from South Padre Island on a regular basis. Booking flights from South Padre Island to Knoxville McGhee Tyson should not be difficult; the airport handles an average of 0 inbound flights from South Padre Island per day.

  • Can I find deals for flights from South Padre Island to Knoxville that include hotel bookings?

    Yes. In addition to deals on South Padre Island to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Padre Island to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Padre Island to Knoxville.

  • Can I find deals for business class flights from South Padre Island to Knoxville?

    Yes. Cheapflights offers flight deals from South Padre Island to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Padre Island to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South Padre Island to Knoxville (average of $296). Flying from South Padre Island to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Padre Island?

Book flights to South Padre Island if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Padre Island to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Nashville flights
Hobby to Nashville flights
Dallas/Fort Worth to Knoxville flights
George Bush Intcntl to Nashville flights
Austin to Nashville flights
Hobby to Knoxville flights
Dallas/Fort Worth to Memphis flights
George Bush Intcntl to Knoxville flights
Love Field to Nashville flights
San Antonio to Nashville flights
Dallas/Fort Worth to Chattanooga flights
Hobby to Memphis flights
Love Field to Memphis flights
San Antonio to Knoxville flights
George Bush Intcntl to Memphis flights
El Paso to Nashville flights
Love Field to Knoxville flights
Hobby to Chattanooga flights
Austin to Memphis flights
San Antonio to Memphis flights
George Bush Intcntl to Chattanooga flights
Austin to Blountville flights
Austin to Knoxville flights
El Paso to Knoxville flights
McAllen to Nashville flights
Amarillo to Knoxville flights
Dallas/Fort Worth to Blountville flights
Hobby to Blountville flights
San Antonio to Chattanooga flights
El Paso to Chattanooga flights
Midland to Knoxville flights
George Bush Intcntl to Blountville flights
Corpus Christi to Knoxville flights
Harlingen to Nashville flights
Love Field to Chattanooga flights
Austin to Chattanooga flights
Corpus Christi to Nashville flights
Lubbock to Chattanooga flights
Midland to Nashville flights
Lubbock to Nashville flights
Love Field to Blountville flights
San Antonio to Blountville flights
Amarillo to Nashville flights
El Paso to Blountville flights
Amarillo to Memphis flights
College Station to Nashville flights
Waco to Nashville flights
Brownsville to Nashville flights
McAllen to Knoxville flights
Wichita Falls to Nashville flights

Top airline flying from South Padre Island to Knoxville

Discover the top airline that operate flights from South Padre Island to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$233Average$348FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.