Knoxville

$199+ Cheap flights from South Dakota to Knoxville (TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — TYS
Apr 5 — Apr 121
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Cheap flight deals from South Dakota to Knoxville

Keep the following information in mind while searching for South Dakota to Knoxville flight deals. Data was last updated March 31, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$199
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$393
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flight deals.
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Knoxville McGhee Tyson flights.
From South Dakota to Knoxville McGhee Tyson
Highest demand for flights based on searches. 23% potential increase in price ($126 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($21 potential savings vs. average RT price).
Average for round-trip flights in March 2025

Find flight deals from South Dakota to Knoxville

Cheapest flights from South Dakota to Knoxville
Explore the most affordable flight options available from South Dakota to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 31, 2025.

This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:39 pmFSD - TYS
1 stop5h 10mAmerican Airlines
Sat 9/206:39 pmTYS - FSD
1 stop6h 20mAmerican Airlines
Deal found 3/30$199
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1411:12 amFSD - TYS
1 stop9h 03mAllegiant Air
Fri 4/1811:13 amTYS - FSD
1 stop8h 14mAllegiant Air
Deal found 3/30$239
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1411:12 amFSD - TYS
2 stops25h 26mMultiple Airlines
Fri 4/1811:13 amTYS - FSD
1 stop8h 14mMultiple Airlines
Deal found 3/30$292
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/34:39 pmRAP - TYS
1 stop5h 20mAmerican Airlines
Tue 7/81:54 pmTYS - RAP
1 stop5h 33mAmerican Airlines
Deal found 3/30$304
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/251:38 pmRAP - TYS
1 stop7h 02mUnited Airlines
Tue 7/14:35 pmTYS - RAP
1 stop7h 25mUnited Airlines
Deal found 3/30$384
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2411:45 amFSD - TYS
2 stops10h 20mUnited Airlines
Thu 5/297:00 amTYS - FSD
1 stop4h 45mUnited Airlines
Deal found 3/30$430
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/244:20 pmFSD - TYS
2 stops6h 31mDelta
Fri 5/305:45 amTYS - FSD
2 stops7h 19mDelta
Deal found 3/31$574
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/52:20 pmRAP - TYS
1 stop6h 36mDelta
Sun 9/76:45 amTYS - RAP
1 stop5h 07mDelta
Deal found 3/30$594

Cheapflights Fare Finder

Customize your flight search to find flights from South Dakota to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
Use the filters below to find and compare flights from South Dakota to Knoxville that are best for you.

Fly from

South Dakota

Fly to

Knoxville

Route

Depart

Return

Price

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Tue 9/16

5:39 pm-11:49 pm

1 stop5h 10m

Knoxville McGhee Tyson

Sat 9/20

6:39 pm-11:59 pm

1 stop6h 20m

$199

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Mon 4/14

11:12 am-9:15 pm

1 stop9h 03m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-6:27 pm

1 stop8h 14m

$239

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Mon 4/14

11:12 am-1:38 pm

2 stops25h 26m

Knoxville McGhee Tyson

Fri 4/18

11:13 am-6:27 pm

1 stop8h 14m

$292

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Thu 7/3

4:39 pm-11:59 pm

1 stop5h 20m

Knoxville McGhee Tyson

Tue 7/8

1:54 pm-5:27 pm

1 stop5h 33m

$304

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Wed 6/25

1:38 pm-10:40 pm

1 stop7h 02m

Knoxville McGhee Tyson

Tue 7/1

4:35 pm-10:00 pm

1 stop7h 25m

$384

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 5/24

11:45 am-11:05 pm

2 stops10h 20m

Knoxville McGhee Tyson

Thu 5/29

7:00 am-10:45 am

1 stop4h 45m

$430

Sioux FallsKnoxville

FSD - TYS

FSDTYS

Sioux Falls Joe Foss Field

Sat 5/24

4:20 pm-11:51 pm

2 stops6h 31m

Knoxville McGhee Tyson

Fri 5/30

5:45 am-12:04 pm

2 stops7h 19m

$574

Rapid CityKnoxville

RAP - TYS

RAPTYS

Rapid City

Fri 9/5

2:20 pm-10:56 pm

1 stop6h 36m

Knoxville McGhee Tyson

Sun 9/7

6:45 am-9:52 am

1 stop5h 07m

$594

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/30

Best time to book a flight from South Dakota to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Dakota with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Dakota to Knoxville

What is the cheapest month to book a flight from South Dakota to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SD to TYS?

Find hourly flight availability from South Dakota to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 31, 2025.

When flying from South Dakota to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 31, 2025.
Read reviews from past customers who have flown Delta, United Airlines and Allegiant Air from South Dakota to Knoxville. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good
8.0
Very good

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
8.0
Very good

Comfort

8.0

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from South Dakota to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Knoxville from South Dakota?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Knoxville from South Dakota.

  • Can I find deals for flights from South Dakota to Knoxville that include hotel bookings?

    Yes. In addition to deals on South Dakota to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Dakota to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Dakota to Knoxville.

  • Can I find deals for business class flights from South Dakota to Knoxville?

    Yes. Cheapflights offers flight deals from South Dakota to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Dakota to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South Dakota to Knoxville (average of $296). Flying from South Dakota to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Dakota?

Book flights to South Dakota if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for South Dakota to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from South Dakota to Knoxville

Discover the top 3 airlines that operate flights from South Dakota to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$221Average$343FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$426FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$487FlexibilityNo cancel feeOn-time69%
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