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Knoxville

$154+ Cheap flights from South Carolina to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — TYS
des. 27 — jan. 31
fr. 12/27
fr. 1/3
1 adult, Economy
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Cheap flight deals from South Carolina to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from South Carolina (USSC) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated Desember 22, 2024.

Round-trip from

$214
(Mytrip)

One-way from

$154
(Delta)
From South Carolina to Knoxville McGhee Tyson
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One-way flight from South Carolina to Knoxville McGhee Tyson
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Find flight deals from South Carolina to Knoxville

Cheapest flights from South Carolina to Knoxville
Explore the most affordable flight options available from South Carolina to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Desember 22, 2024.

This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 12/225:13 amMYR - TYS
1 stop5h 11mAmerican Airlines
sø. 12/299:08 amTYS - MYR
1 stop5h 00mAmerican Airlines
Deal found 12/20$438
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ti. 12/246:14 pmCLT - TYS
Nonstop1h 13mAmerican Airlines
to. 12/266:01 pmTYS - CLT
Nonstop1h 22mAmerican Airlines
Deal found 12/21$584
This American Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 12/258:58 amSAV - TYS
1 stop5h 08mAmerican Airlines
on. 1/19:08 amTYS - SAV
1 stop5h 06mAmerican Airlines
Deal found 12/20$628
This Mytrip deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 12/228:46 pmCHS - TYS
2 stops24h 26mMultiple Airlines
ti. 12/246:20 amTYS - CHS
2 stops9h 24mMultiple Airlines
Deal found 12/21$668
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 12/225:27 pmCHS - TYS
1 stop4h 44mDelta
on. 12/258:07 amTYS - CHS
1 stop3h 10mDelta
Deal found 12/21$718
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
fr. 12/279:42 amCLT - TYS
1 stop4h 10mDelta
sø. 12/296:36 pmTYS - CLT
1 stop3h 33mDelta
Deal found 12/21$728
This Mytrip deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 12/229:38 pmMYR - TYS
2 stops23h 12mMultiple Airlines
sø. 12/296:46 pmTYS - MYR
2 stops15h 45mMultiple Airlines
Deal found 12/20$736
This Mytrip deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 12/268:49 pmCLT - TYS
2 stops21h 31mMultiple Airlines
sø. 12/299:13 pmTYS - CLT
2 stops22h 28mMultiple Airlines
Deal found 12/21$774
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
to. 12/262:52 pmCLT - TYS
1 stop19h 47mUnited Airlines
sø. 12/299:50 amTYS - CLT
1 stop24h 13mUnited Airlines
Deal found 12/21$892
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
on. 12/252:13 pmSAV - TYS
2 stops20h 26mUnited Airlines
on. 1/15:45 amTYS - SAV
2 stops18h 01mUnited Airlines
Deal found 12/20$1,007
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sø. 12/221:32 pmMYR - TYS
2 stops20h 33mUnited Airlines
sø. 12/295:35 pmTYS - MYR
2 stops19h 02mUnited Airlines
Deal found 12/20$3,386

Find flights from South Carolina to Knoxville within your budget

Customize your flight search to find flights from South Carolina to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Desember 22, 2024.

Fly from

Any airport

Fly to

Any airport

Route

Depart

Return

Price

Myrtle BeachKnoxville

MYR - TYS

MYRTYS

Myrtle Beach Intl

lø. 1/11

9:05 am-8:41 pm

1 stop11h 36m

Knoxville McGhee Tyson

ma. 1/13

9:15 am-3:01 pm

1 stop5h 46m

$214

Myrtle BeachKnoxville

MYR - TYS

MYRTYS

Myrtle Beach Intl

to. 1/23

8:07 pm-11:58 pm

1 stop3h 51m

Knoxville McGhee Tyson

ma. 1/27

6:11 pm-11:51 pm

1 stop5h 40m

$228

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

fr. 1/3

8:46 pm-11:10 am

1 stop14h 24m

Knoxville McGhee Tyson

sø. 1/5

4:58 pm-7:51 pm

2 stops26h 53m

$291

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

sø. 1/19

6:10 am-6:55 pm

1 stop12h 45m

Knoxville McGhee Tyson

sø. 1/26

7:30 am-11:28 pm

2 stops15h 58m

$313

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

on. 2/5

6:00 am-4:09 pm

1 stop10h 09m

Knoxville McGhee Tyson

on. 2/12

11:52 am-8:49 pm

1 stop8h 57m

$343

SavannahKnoxville

SAV - TYS

SAVTYS

Savannah/Hilton Head

fr. 2/21

10:58 am-3:45 pm

1 stop4h 47m

Knoxville McGhee Tyson

ma. 2/24

6:00 pm-9:47 pm

1 stop3h 47m

$398

SavannahKnoxville

SAV - TYS

SAVTYS

Savannah/Hilton Head

fr. 1/17

5:35 am-9:16 am

1 stop3h 41m

Knoxville McGhee Tyson

fr. 1/24

5:45 am-11:07 am

1 stop5h 22m

$408

CharlestonKnoxville

CHS - TYS

CHSTYS

Charleston

fr. 1/17

8:25 pm-11:58 pm

1 stop3h 33m

Knoxville McGhee Tyson

fr. 1/24

6:11 pm-10:03 pm

1 stop3h 52m

$408

CharlotteKnoxville

CLT - TYS

CLTTYS

Charlotte Douglas

fr. 2/7

1:13 pm-9:56 pm

1 stop8h 43m

Knoxville McGhee Tyson

sø. 2/9

7:17 pm-6:42 am

1 stop11h 25m

$437

Hilton Head IslandKnoxville

HHH - TYS

HHHTYS

Hilton Head Island

to. 1/9

2:48 pm-7:35 pm

1 stop4h 47m

Knoxville McGhee Tyson

ma. 1/13

11:02 am-2:18 pm

1 stop3h 16m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/20

Showing 1-10 of 19 results
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Best time to book a flight from South Carolina to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from South Carolina to Knoxville

Get recent, data-driven insights about flights from South Carolina to Knoxville including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from South Carolina to Knoxville?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Knoxville (average of $304). Flying from South Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to TYS?

Find hourly flight availability from South Carolina to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated Desember 22, 2024.

When flying from South Carolina to Knoxville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated Desember 22, 2024.
Get a feel of what it's like to fly with Delta, American Airlines and United Airlines from South Carolina to Knoxville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
8,594 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Delta
8.0
Very good
8,594 reviews
Delta
8.0
Very good
8,594 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

United Airlines
7.4
Good
9,028 reviews
Delta
8.0
Very good
8,594 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
8,594 reviews

Comfort

8.0

Food

7.3

Boarding

8.2

Crew

8.6

Entertainment

7.9

Overall

8.0

Reviews

1 / 10

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from South Carolina?

    For a flight from South Carolina to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • What are the cheapest airlines to fly from South Carolina to Knoxville one-way?

    The cheapest airlines for a one-way flight from South Carolina to Knoxville are Delta ($154), American Airlines ($185), and United Airlines ($338).

  • What are the most popular routes from South Carolina to Knoxville?

    Most travelers choose Charlotte Douglas - Knoxville McGhee Tyson, Charleston - Knoxville McGhee Tyson or Savannah/Hilton Head - Knoxville McGhee Tyson when deciding on the best route from South Carolina to Knoxville.

  • Can I find deals for flights from South Carolina to Knoxville that include hotel bookings?

    Yes. In addition to deals on South Carolina to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Knoxville.

  • Can I find deals for business class flights from South Carolina to Knoxville?

    Yes. Cheapflights offers flight deals from South Carolina to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Knoxville (average of $304). Flying from South Carolina to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Knoxville

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Top 2 airlines flying from South Carolina to Knoxville

Discover the top 2 airlines that operate flights from South Carolina to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Desember 22, 2024.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$253Average$518FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$254Average$493FlexibilityNo cancel feeOn-time71%
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